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List of works by Andrzej Mackiewicz

A Clinical Outcome of the Anti-PD-1 Therapy of Melanoma in Polish Patients Is Mediated by Population-Specific Gut Microbiome Composition

A designer hyper interleukin 11 (H11) is a biologically active cytokine.

scientific article

A high proportion of founder BRCA1 mutations in Polish breast cancer families

scientific article

Adjuvant vemurafenib in resected, BRAFV600 mutation-positive melanoma (BRIM8): a randomised, double-blind, placebo-controlled, multicentre, phase 3 trial

scientific article published on 21 February 2018

Adult stem cells and their trans-differentiation potential--perspectives and therapeutic applications

scientific article

Analysis of mutations in the p16/CDKN2A gene in sporadic and familial melanoma in the Polish population

scientific article published on 01 January 2002

Analysis of sequence variants in the 3'UTR of CDKN2A gene in melanoma patients

scientific article published on 28 September 2015

Anticancer drugs of tomorrow: apoptotic pathways as targets for drug design

scientific article

Anticancer immunotherapy by CTLA-4 blockade: obligatory contribution of IL-2 receptors and negative prognostic impact of soluble CD25.

scientific article

BNIP3L Is a New Autophagy Related Prognostic Biomarker for Melanoma Patients Treated With AGI-101H

scientific article published on 01 July 2020

BRAF and MEK inhibitors in the era of immunotherapy in melanoma patients

scientific article

BRCA2 mutations and androgen receptor expression as independent predictors of outcome of male breast cancer patients.

scientific article published in October 2003

Bioengineering the spider silk sequence to modify its affinity for drugs

Blending two bioengineered spider silks to develop cancer targeting spheres

scientific article published on 05 April 2017

Cancer immunotherapy using cells modified with cytokine genes

scientific article published on January 1, 2003

Captopril, an angiotensin-converting enzyme inhibitor, promotes growth of immunogenic tumors in mice.

scientific article published on July 2006

Cellular Vaccines Modified with Hyper IL6 or Hyper IL11 Combined with Docetaxel in an Orthotopic Prostate Cancer Model

scientific article published on 01 June 2015

Cellular uptake, intracellular distribution and degradation of Her2-targeting silk nanospheres

scientific article published on 26 August 2019

Clinical trials of active cancer immunotherapy

scientific article published on 01 August 2007

Comparison of dabrafenib and trametinib combination therapy with vemurafenib monotherapy on health-related quality of life in patients with unresectable or metastatic cutaneous BRAF Val600-mutation-positive melanoma (COMBI-v): results of a phase 3, o

article

Complete tumour regressions induced by vaccination with IL-12 gene-transduced tumour cells in combination with IL-15 in a melanoma model in mice

scientific article published on 07 November 2003

Composite spheres made of bioengineered spider silk and iron oxide nanoparticles for theranostics applications.

scientific article published on 15 July 2019

CpG immunostimulatory oligodeoxynucleotide 1826 enhances antitumor effect of interleukin 12 gene-modified tumor vaccine in a melanoma model in mice

scientific article published on June 2004

Cyclosporine A and its non-immunosuppressive derivative NIM811 induce apoptosis of malignant melanoma cells in in vitro and in vivo studies

scientific article published in October 2005

Delivery of chemotherapeutics using spheres made of bioengineered spider silks derived from MaSp1 and MaSp2 proteins

scientific article published on 17 January 2018

Design of clinical trials for therapeutic cancer vaccines development

scientific article published on 14 October 2009

Designer cytokine hyper interleukin 11 (H11) is a megakaryopoietic factor

scientific article

Development of a new, simple and cost-effective diagnostic tool for genetic screening of hereditary colorectal cancer--the DNA microarray assay

scientific article published on June 6, 2013

Diagnostics of Mutations in MMR/EPCAM Genes and Their Role in the Treatment and Care of Patients with Lynch Syndrome

scientific article published on 05 October 2020

Drug affinity and targeted delivery: double functionalization of silk spheres for controlled doxorubicin delivery into Her2-positive cancer cells

scientific article published on 30 March 2020

EPR Study of Iron Ion Complexes in Human Blood ⬇️

scientific article published on April 5, 2011

Effects of Designer Hyper-Interleukin 11 (H11) on Hematopoiesis in Myelosuppressed Mice

scientific article

Efficacy and safety of ipilimumab therapy in patients with metastatic melanoma: a retrospective multicenter analysis

scientific article published on 28 June 2013

Engineered spider silk: the intelligent biomaterial of the future. Part I

scientific article published on 17 June 2011

Engineered spider silk: the intelligent biomaterial of the future. Part II

scientific article published on 17 June 2011

Erratum: anticancer immunotherapy by CTLA-4 blockade: obligatory contribution of IL-2 receptors and negative prognostic impact of soluble CD25.

scientific article published in March 2015

Expression of PiT1 and PiT2 retroviral receptors and transduction efficiency of tumor cells.

scientific article published in January 2002

Expression of p16 in sporadic primary uveal melanoma

scientific article published on 01 January 2002

Expression of soluble recombinant TGF-beta type II receptor fused with the Fc portion of human IgG1 (sTbetaRII-Fc) in NS0 cells.

scientific article published on 30 May 2006

Five-Year Outcomes with Dabrafenib plus Trametinib in Metastatic Melanoma.

scientific article

Functional T Cell Reactivity to Melanocyte Antigens Is Lost during the Progression of Malignant Melanoma, but Is Restored by Immunization

Functionalized bioengineered spider silk spheres improve nuclease resistance and activity of oligonucleotide therapeutics providing a strategy for cancer treatment.

scientific article

Functionalized silk spheres selectively and effectively deliver a cytotoxic drug to targeted cancer cells in vivo

scientific article published on 01 December 2020

Functionalized spider silk spheres as drug carriers for targeted cancer therapy

scientific article

Gene modified tumor vaccines in therapy of malignant melanoma

scientific article published in January 2002

Health-related quality of life in patients with fully resected BRAFV600 mutation-positive melanoma receiving adjuvant vemurafenib.

scientific article

Hereditary ovarian cancer in Poland.

scientific article published in October 2003

Heterotypic breast cancer model based on a silk fibroin scaffold to study the tumor microenvironment.

scientific article published on 22 December 2017

How Do Machines Learn? Artificial Intelligence as a New Era in Medicine

Hyper-interleukin-11 novel designer molecular adjuvant targeting gp130 for whole cell cancer vaccines.

scientific article published on 14 October 2011

Immunotargeting of cancer stem cells

scientific article

Immunotherapy Bridge 2017 and Melanoma Bridge 2017: meeting abstracts

scientific article published on 15 January 2018

Implementation of a dynamic culture condition to the heterotypic 3D breast cancer model

scientific article published on 16 August 2019

Improved overall survival in melanoma with combined dabrafenib and trametinib

scientific article

Interleukin 12-based immunotherapy improves the antitumor effectiveness of a low-dose 5-Aza-2'-deoxycitidine treatment in L1210 leukemia and B16F10 melanoma models in mice

scientific article published in August 2003

Interleukin 15 augments antitumor activity of cytokine gene-modified melanoma cell vaccines in a murine model.

scientific article published in May 2008

Intratumoral induction of CD103 triggers tumor-specific CTL function and CCR5-dependent T-cell retention

scientific article

Ipilimumab 10 mg/kg versus ipilimumab 3 mg/kg in patients with unresectable or metastatic melanoma: a randomised, double-blind, multicentre, phase 3 trial

scientific article published on 27 March 2017

Is AJCC 8th Edition useful in qualifying melanoma patients to adjuvant therapy?

scientific article published on 01 July 2020

It Runs in the Bromodomain Family: Speckled Proteins (SP) Play a Role in the Antitumor Immune Response in Solid Tumors

scientific article published in 2022

Large randomized study of thymosin alpha 1, interferon alfa, or both in combination with dacarbazine in patients with metastatic melanoma

scientific article published in March 2010

Liquid lncRNA Biopsy for the Evaluation of Locally Advanced and Metastatic Squamous Cell Carcinomas of the Head and Neck

scientific article published on 16 September 2020

Long-term survival of high-risk melanoma patients immunized with a Hyper-IL-6-modified allogeneic whole-cell vaccine after complete resection

scientific article published on 01 June 2012

Low Levels of TRIM28-Interacting KRAB-ZNF Genes Associate with Cancer Stemness and Predict Poor Prognosis of Kidney Renal Clear Cell Carcinoma Patients

Melanoma Stem Cell-Like Phenotype and Significant Suppression of Immune Response within a Tumor Are Regulated by TRIM28 Protein

scientific article published on 15 October 2020

Mining Transcriptomic Data to Uncover the Association between CBX Family Members and Cancer Stemness

scientific article published in 2022

Murine GFP-Mx1 forms nuclear condensates and associates with cytoplasmic intermediate filaments: novel antiviral activity against VSV

scientific article published on 19 October 2020

Myeloid-Derived Suppressor Cells (MDSC) in Melanoma Patients Treated with Anti-PD-1 Immunotherapy

Natural T cell autoreactivity to melanoma antigens: clonally expanded melanoma-antigen specific CD8 + memory T cells can be detected in healthy humans

scientific article published on 19 February 2019

Novel Genetic Melanoma Vaccines Based on Induced Pluripotent Stem Cells or Melanosphere-Derived Stem-Like Cells Display High Efficacy in a Murine Tumor Rejection Model

scientific article published on 26 March 2020

Oncogenic BRAF mutations and p16 expression in melanocytic nevi and melanoma in the Polish population

scientific article published on 31 October 2017

Oncogenic Role of ZFAS1 lncRNA in Head and Neck Squamous Cell Carcinomas

scientific article published on 21 April 2019

Optimization of a retroviral vector for transduction of human CD34 positive cells.

scientific article published on 11 December 2006

Optimization of spider silk sphere formation processing conditions to obtain carriers with controlled characteristics

scientific article published on 22 September 2018

Overall survival at 5 years of follow-up in a phase III trial comparing ipilimumab 10 mg/kg with 3 mg/kg in patients with advanced melanoma

scientific article published on 01 June 2020

P53 and P16 gene mutations in non-small cell lung cancer

scientific article published in January 2002

PRINS lncRNA Is a New Biomarker Candidate for HPV Infection and Prognosis of Head and Neck Squamous Cell Carcinomas

scientific article published on 28 September 2020

Plasma lncRNA expression profile as a prognostic tool in BRAF-mutant metastatic melanoma patients treated with BRAF inhibitor.

scientific article published on 11 June 2019

Primary resistance to docetaxel-based chemotherapy in metastatic breast cancer patients correlates with a high frequency of BRCA1 mutations

scientific article published in July 2008

Programmed cell death 1 checkpoint inhibitors in the treatment of patients with advanced melanoma

scientific article published on 22 March 2017

Purification and cytotoxicity of tag-free bioengineered spider silk proteins

scientific article published on 3 August 2012

Re-induction using whole cell melanoma vaccine genetically modified to melanoma stem cells-like beyond recurrence extends long term survival of high risk resected patients - updated results

scientific article published on 29 November 2018

Recent advances in melanoma treatment - American Society of Clinical Oncology (ASCO) 2012 perspective

scientific article published on July 6, 2012

SARS-CoV-2: Pathogenesis, and Advancements in Diagnostics and Treatment

scientific article published on 06 October 2020

Screening with Magnetic Resonance Imaging in women at low and intermediate risk of breast Cancer

Screening with magnetic resonance imaging, mammography and ultrasound in women at average and intermediate risk of breast cancer

scientific article published on March 2017

Silk as an innovative biomaterial for cancer therapy

scientific article

Somatic mutations in the BRCA2 gene and high frequency of allelic loss of BRCA2 in sporadic male breast cancer

scientific article published on April 2002

TRIM28 epigenetic corepressor is indispensable for stable induced pluripotent stem cell formation.

scientific article

TRIM28 multi-domain protein regulates cancer stem cell population in breast tumor development.

scientific article

Targeted therapy of renal cell cancer

scientific article published on June 2008

The Association between TIF1 Family Members and Cancer Stemness in Solid Tumors

The CDKN2a common variants: 148 Ala/Thr and 500 C/G in 3' UTR, and their association with clinical course of melanoma

scientific article published on 09 March 2007

The Landscape of Transmembrane Protein Family Members in Head and Neck Cancers: Their Biological Role and Diagnostic Utility

The Oncogenic Roles of PTTG1 and PTTG2 Genes and Pseudogene PTTG3P in Head and Neck Squamous Cell Carcinomas

scientific article published on 18 August 2020

The Tumor and Host Immune Signature, and the Gut Microbiota as Predictive Biomarkers for Immune Checkpoint Inhibitor Response in Melanoma Patients

scientific article published on 25 September 2020

The anti-cancer actions of O6-methylguanine-DNA-methyltransferase in relation to colon polyps

scientific article published on 8 July 2014

The expression signature of cancer-associated KRAB-ZNF factors identified in TCGA pan-cancer transcriptomic data

scientific article published on 16 February 2019

The method of purifying bioengineered spider silk determines the silk sphere properties.

scientific article published on 17 June 2016

The mystery of let-7d - a small RNA with great power

scientific article

The role of NEAT1 lncRNA in squamous cell carcinoma of the head and neck is still difficult to define

scientific article published on 03 July 2020

The role of TRIM family proteins in the regulation of cancer stem cell self-renewal

scientific article published on 09 November 2019

Therapeutic gene modified cell based cancer vaccines

scientific article published on 06 April 2013

Therapeutic melanoma vaccine with cancer stem cell phenotype represses exhaustion and maintains antigen-specific T cell stemness by up-regulating BCL6

scientific article published on 11 January 2020

Three-year pooled analysis of factors associated with clinical outcomes across dabrafenib and trametinib combination therapy phase 3 randomised trials

scientific article

Whole Cell Therapeutic Vaccine Modified With Hyper-IL6 for Combinational Treatment of Nonresected Advanced Melanoma

scientific article

Wound fluids affect miR-21, miR-155 and miR-221 expression in breast cancer cell lines, and this effect is partially abrogated by intraoperative radiation therapy treatment

scientific article published on 3 August 2017

lncRNA Expression after Irradiation and Chemoexposure of HNSCC Cell Lines

scientific article published on 14 November 2018

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