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List of works by Stephan Menne

AIC649 Induces a Bi-Phasic Treatment Response in the Woodchuck Model of Chronic Hepatitis B.

scientific article published on 14 December 2015

Antiviral Efficacy and Host Immune Response Induction during Sequential Treatment with SB 9200 Followed by Entecavir in Woodchucks.

scientific article

Antiviral Efficacy and Host Innate Immunity Associated with SB 9200 Treatment in the Woodchuck Model of Chronic Hepatitis B

scientific article

Antiviral effect of oral administration of tenofovir disoproxil fumarate in woodchucks with chronic woodchuck hepatitis virus infection

scientific article

Antiviral effect of orally administered (-)-beta-D-2-aminopurine dioxolane in woodchucks with chronic woodchuck hepatitis virus infection

scientific article

Antiviral effects of lamivudine, emtricitabine, adefovir dipivoxil, and tenofovir disoproxil fumarate administered orally alone and in combination to woodchucks with chronic woodchuck hepatitis virus infection

scientific article published on August 2008

Assessment of peripheral blood mononuclear cell proliferation by [2-3H]adenine uptake in the woodchuck model

scientific article published on 01 March 1996

Capacity of a natural strain of woodchuck hepatitis virus, WHVNY, to induce acute infection in naive adult woodchucks

scientific article published on 12 May 2015

Characterization and genotyping of the DRB1 gene of the major histocompatibility complex (MHC) in the Marmota monax, animal model of hepatitis B.

scientific article published on February 2015

Characterization of T-cell response to woodchuck hepatitis virus core protein and protection of woodchucks from infection by immunization with peptides containing a T-cell epitope.

scientific article

Chemoimmunotherapy of chronic hepatitis B virus infection in the woodchuck model overcomes immunologic tolerance and restores T-cell responses to pre-S and S regions of the viral envelope protein

scientific article

Clevudine therapy with vaccine inhibits progression of chronic hepatitis and delays onset of hepatocellular carcinoma in chronic woodchuck hepatitis virus infection

scientific article published in December 2004

Correction: Intrahepatic Transcriptional Signature Associated with Response to Interferon-α Treatment in the Woodchuck Model of Chronic Hepatitis B.

scientific article published on 29 March 2016

Correlation of virus and host response markers with circulating immune complexes during acute and chronic woodchuck hepatitis virus infection

scientific article published on 03 December 2008

Cryo-EM structures of human hepatitis B and woodchuck hepatitis virus small spherical subviral particles

scientific article published in 2022

Deficiencies in the acute-phase cell-mediated immune response to viral antigens are associated with development of chronic woodchuck hepatitis virus infection following neonatal inoculation

scientific article

Determination of peripheral blood mononuclear cell responses to mitogens and woodchuck hepatitis virus core antigen in woodchucks by 5-bromo-2′-deoxyuridine or 2[3H]adenine incorporation ⬇️

scientific article published on January 1, 1997

Dose-Dependent Sorafenib-Induced Immunosuppression Is Associated with Aberrant NFAT Activation and Expression of PD-1 in T Cells

scientific article published on 16 May 2019

Down-regulation of hepatitis delta virus super-infection in the woodchuck model

scientific article published on 04 March 2019

Efficacy of an Inhibitor of Hepatitis B Virus Expression in Combination With Entecavir and Interferon-α in Woodchucks Chronically Infected With Woodchuck Hepatitis Virus

scientific article published on 22 April 2020

Electroporation enhances immunogenicity of a DNA vaccine expressing woodchuck hepatitis virus surface antigen in woodchucks

scientific article

Envelope proteins derived from naturally integrated hepatitis B virus DNA support assembly and release of infectious hepatitis delta virus particles.

scientific article published on 12 March 2014

Expression of matrix metalloproteinases and their inhibitors in the woodchuck model of hepatocellular carcinoma

scientific article published on 17 April 2013

Gene therapy for HCV/HBV-induced hepatocellular carcinoma

scientific article published on December 1, 2010

Glucosidase inhibition enhances presentation of de-N-glycosylated hepatitis B virus epitopes by major histocompatibility complex class I in vitro and in woodchucks

scientific article published on October 2010

Hepatitis delta virus infects the cells of hepadnavirus-induced hepatocellular carcinoma in woodchucks.

scientific article

Hepatocellular carcinoma in the woodchuck model of hepatitis B virus infection

scientific article published in November 2004

Identification of CD4+ and CD8+ T cell epitopes of woodchuck hepatitis virus core and surface antigens in BALB/c mice.

scientific article published on July 2010

Identification of an intrahepatic transcriptional signature associated with self-limiting infection in the woodchuck model of hepatitis B ⬇️

scientific article published on January 1, 2013

Immunization with surface antigen vaccine alone and after treatment with 1-(2-fluoro-5-methyl-beta-L-arabinofuranosyl)-uracil (L-FMAU) breaks humoral and cell-mediated immune tolerance in chronic woodchuck hepatitis virus infection

scientific article

Immunogenic effects of woodchuck hepatitis virus surface antigen vaccine in combination with antiviral therapy: breaking of humoral and cellular immune tolerance in chronic woodchuck hepatitis virus infection

scientific article

Immunogenicity in mice and rabbits of DNA vaccines expressing woodchuck hepatitis virus antigens

scientific article published on 2 June 2008

Immunomodulation as an option for the treatment of chronic hepatitis B virus infection: preclinical studies in the woodchuck model

scientific article published on June 2007

Immunosuppression reactivates viral replication long after resolution of woodchuck hepatitis virus infection

scientific article published in March 2007

Induction of antibodies to the PreS region of surface antigens of woodchuck hepatitis virus (WHV) in chronic carrier woodchucks by immunizations with WHV surface antigens

scientific article published in September 2003

Infection Patterns Induced in Naive Adult Woodchucks by Virions of Woodchuck Hepatitis Virus Collected during either the Acute or Chronic Phase of Infection.

scientific article

Innate and adaptive immunity associated with resolution of acute woodchuck hepatitis virus infection in adult woodchucks

scientific article published on 23 December 2019

Interferon-gamma-associated responses to woodchuck hepatitis virus infection in neonatal woodchucks and virus-infected hepatocytes

scientific article published in September 2004

Intrahepatic Transcriptional Signature Associated with Response to Interferon-α Treatment in the Woodchuck Model of Chronic Hepatitis B

scientific article (publication date: September 2015)

Kinetics of viremia and acute liver injury in relation to outcome of neonatal woodchuck hepatitis virus infection

scientific article published in March 2004

Liver-Targeted Toll-Like Receptor 7 Agonist Combined With Entecavir Promotes a Functional Cure in the Woodchuck Model of Hepatitis B Virus

scientific article published on 08 July 2019

Liver-directed gene therapy of chronic hepadnavirus infection using interferon alpha tethered to apolipoprotein A-I.

scientific article published on 12 March 2015

Measurement of Antiviral Effect and Innate Immune Response During Treatment of Primary Woodchuck Hepatocytes

scientific article published on January 2017

Measurement of cell-mediated immune response in woodchucks.

scientific article

Modulation of regulatory T-cell activity in combination with interleukin-12 increases hepatic tolerogenicity in woodchucks with chronic hepatitis B.

scientific article

Modulators of innate immunity as novel therapeutics for treatment of chronic hepatitis B.

scientific article published on 11 February 2018

Prevention of liver tumor formation in woodchucks with established hepatocellular carcinoma by treatment with cationic liposome-DNA complexes

scientific article

Rapid immunity to vaccination with woodchuck hepatitis virus surface antigen using cationic liposome-DNA complexes as adjuvant

scientific article published in October 2009

Real-time polymerase chain reaction assays for leukocyte CD and cytokine mRNAs of the Eastern woodchuck (Marmota monax)

scientific article published on 01 August 2002

Role of type 1 versus type 2 immune responses in liver during the onset of chronic woodchuck hepatitis virus infection

scientific article published on April 2003

Safety and efficacy of anti-PD-L1 therapy in the woodchuck model of HBV infection.

scientific article published on 14 February 2018

Semliki forest virus expressing interleukin-12 induces antiviral and antitumoral responses in woodchucks with chronic viral hepatitis and hepatocellular carcinoma.

scientific article published on 09 September 2009

Small Animal Models for Human Immunodeficiency Virus (HIV), Hepatitis B, and Tuberculosis: Proceedings of an NIAID Workshop

scientific article published on 01 January 2020

Subset of Suz12/PRC2 target genes is activated during hepatitis B virus replication and liver carcinogenesis associated with HBV X protein

scientific article published on October 2012

Suitability of the woodchuck HCC as a preclinical model for evaluation of intra-arterial therapies

scientific article published on 09 February 2020

Superinfection with woodchuck hepatitis virus strain WHVNY of livers chronically infected with strain WHV7

scientific article

Support of the infectivity of hepatitis delta virus particles by the envelope proteins of different genotypes of hepatitis B virus

scientific article

Sustained efficacy and seroconversion with the Toll-like receptor 7 agonist GS-9620 in the Woodchuck model of chronic hepatitis B

scientific article

T-Cell Response to Woodchuck Hepatitis Virus (WHV) Antigens during Acute Self-Limited WHV Infection and Convalescence and after Viral Challenge ⬇️

scientific article published on July 1, 1998

The Genome Sequence of the Eastern Woodchuck (Marmota monax) - A Preclinical Animal Model for Chronic Hepatitis B

scientific article published on 03 December 2019

The woodchuck as an animal model for pathogenesis and therapy of chronic hepatitis B virus infection

scientific article

Thymidine utilization abnormality in proliferating lymphocytes and hepatocytes of the woodchuck

scientific article published on February 2001

Toll-Like Receptor 8 Agonist GS-9688 Induces Sustained Efficacy in the Woodchuck Model of Chronic Hepatitis B

scientific article published on 04 April 2020

Transcriptomic analysis of the woodchuck model of chronic hepatitis B ⬇️

scientific article published on July 12, 2012

Treatment of Chronic Viral Hepatitis in Woodchucks by Prolonged Intrahepatic Expression of Interleukin-12.

scientific article

Treatment of chronic viral hepatitis in woodchucks by prolonged intrahepatic expression of interleukin-12.

scientific article published on 30 December 2008

Unraveling hepatitis B virus infection of mice and men (and woodchucks and ducks)

scientific article published in October 1999

Woodchuck dendritic cells generated from peripheral blood mononuclear cells and transduced with recombinant human adenovirus serotype 5 induce antigen-specific cellular immune responses

scientific article published in May 2007

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