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List of works by Jason A Koutcher

1H magnetic resonance spectroscopy of prostate cancer: biomarkers for tumor characterization

scientific article published on January 2008

31P MR spectroscopic imaging detects regenerative changes in human liver stimulated by portal vein embolization

scientific article

31P NMR spectra of extremity sarcomas: diversity of metabolic profiles and changes in response to chemotherapy

scientific article published on 01 October 1990

A birdcage resonator for intracavitary MR imaging

scientific article published on 01 January 1993

A dual-tuned resonator for proton-decoupled phosphorus-31 chemical shift imaging of the brain

scientific article

A fluorine-labeled methotrexate as a probe for monitoring tumor antifolate pharmacokinetics: synthesis, in vitro cytotoxicity, and pilot in vivo 19F magnetic resonance spectra ⬇️

scientific article published on October 1, 2003

A quantitative assessment of liver metabolites during jaundice using three dimensional phosphorus chemical shift imaging

scientific article published on 01 February 2000

Accuracy and reproducibility of tumor positioning during prolonged and multi-modality animal imaging studies

scientific article published on 30 September 2008

An 19F magnetic resonance-based in vivo assay of solid tumor methotrexate resistance: proof of principle.

scientific article published on February 2005

An Exploratory Study of Endorectal Magnetic Resonance Imaging and Spectroscopy of the Prostate as Preoperative Predictive Biomarkers of Biochemical Relapse After Radical Prostatectomy ⬇️

scientific article published on October 16, 2010

An analysis of the intrinsic resonance offset dependence of magnetization generated by stimulated echo pulse sequences for noncoupled spins

scientific article published in January 1991

Anatomic segmentation improves prostate cancer detection with artificial neural networks analysis of 1H magnetic resonance spectroscopic imaging.

scientific article

Atrasentan (ABT-627) enhances perfusion and reduces hypoxia in a human tumor xenograft model

scientific article published on 22 October 2009

Automation of pattern recognition analysis of dynamic contrast-enhanced MRI data to characterize intratumoral vascular heterogeneity

scientific article published on 20 July 2017

Average arterial input function for quantitative dynamic contrast enhanced magnetic resonance imaging of neck nodal metastases

scientific article

Changes in radiation sensitization induced by Fluosol-DA as measured by 31P nuclear magnetic resonance spectroscopy

Chronic prostatitis: MR imaging and 1H MR spectroscopic imaging findings--initial observations

scientific article

Correlation of proton MR spectroscopic imaging with gleason score based on step-section pathologic analysis after radical prostatectomy

scientific article

Corrigendum to "Noninvasive Multimodality Imaging of the Tumor Microenvironment: Registered Dynamic Magnetic Resonance Imaging and Positron Emission Tomography Studies of a Preclinical Tumor Model of Tumor Hypoxia" [Neoplasia 11 (2009) 247-259]

scientific article published on December 2016

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

scientific article

DNA and protein changes caused by disease in human breast tissues probed by the Kubelka-Munk spectral functional

scientific article

Detection and quantitative analysis of early stage orthotopic murine bladder tumor using in vivo magnetic resonance imaging.

scientific article

Detection of prostate cancer with MR spectroscopic imaging: an expanded paradigm incorporating polyamines

scientific article published on 21 September 2007

Development of a new reporter gene system--dsRed/xanthine phosphoribosyltransferase-xanthine for molecular imaging of processes behind the intact blood-brain barrier

scientific article published on April 2003

Development of new mouse lung tumor models expressing EGFR T790M mutants associated with clinical resistance to kinase inhibitors

scientific article

Diagnostic usefulness of water-to-fat ratio and choline concentration in malignant and benign breast lesions and normal breast parenchyma: an in vivo (1) H MRS study

scientific article

Differential p53-independent outcomes of p19(Arf) loss in oncogenesis

scientific article

Discrimination of benign and malignant breast lesions by using shutter-speed dynamic contrast-enhanced MR imaging

scientific article

Distinguishing Metastatic Triple Negative Breast Cancer from Non-metastatic Breast Cancer using SHG Imaging and Resonance Raman Spectroscopy

scientific article published on 26 March 2020

Dose-dependent effects of platelet-derived growth factor-B on glial tumorigenesis

scientific article published on July 2004

Doubly tuned solenoidal resonators for small animal imaging and spectroscopy at 1.5 Tesla

scientific article published on 01 March 1989

Dual targeting of EGFR can overcome a major drug resistance mutation in mouse models of EGFR mutant lung cancer

scientific article published on 14 September 2009

Dynamic contrast-enhanced magnetic resonance imaging as a predictor of outcome in head-and-neck squamous cell carcinoma patients with nodal metastases

scientific article

ETV4 promotes metastasis in response to activation of PI3-kinase and Ras signaling in a mouse model of advanced prostate cancer.

scientific article published on 05 August 2013

Effect of 6-aminonicotinamide on the pentose phosphate pathway: 31P NMR and tumor growth delay studies

scientific article published on 01 December 1996

Effect of radiotherapy and chemotherapy on composition of tumor membrane phospholipids

scientific article published on 01 January 1997

Evaluation of chemotherapy and radiation enhancement and 31P NMR spectral changes induced by biochemical modulation

scientific article published on 01 January 1997

Evidence for shutter-speed variation in CR bolus-tracking studies of human pathology.

scientific article

Expression of the bifunctional suicide gene CDUPRT increases radiosensitization and bystander effect of 5-FC in prostate cancer cells

scientific article

Extension of the intravoxel incoherent motion model to non‐gaussian diffusion in head and neck cancer ⬇️

scientific article published on July 23, 2012

Fat-free MRI based on magnetization exchange

scientific article

Feasibility of using limited-population-based arterial input function for pharmacokinetic modeling of osteosarcoma dynamic contrast-enhanced MRI data

scientific article

Feasibility of using limited-population-based average R10 for pharmacokinetic modeling of osteosarcoma dynamic contrast-enhanced magnetic resonance imaging data

scientific article

High-field small animal magnetic resonance oncology studies.

scientific article

High-resolution imaging of bone precursor cells within the intact bone marrow cavity of living mice.

scientific article published in July 2005

Hypoxia targeted bifunctional suicide gene expression enhances radiotherapy in vitro and in vivo ⬇️

scientific article published on August 29, 2012

Identification of a tumour suppressor network opposing nuclear Akt function

scientific article

Identification of prognostic markers in bone sarcomas using proton-decoupled phosphorus magnetic resonance spectroscopy.

scientific article published in December 2003

Image-fusion of MR spectroscopic images for treatment planning of gliomas.

scientific article published in January 2006

Imaging endogenous macrophage iron deposits reveals a metabolic biomarker of polarized tumor macrophage infiltration and response to CSF1R breast cancer immunotherapy

scientific article published in Scientific Reports

Imaging intratumoral convection: pressure-dependent enhancement in chemotherapeutic delivery to solid tumors

scientific article published on January 2009

Imaging of alkaline phosphatase activity in bone tissue

scientific article

Imaging of dihydrofolate reductase fusion gene expression in xenografts of human liver metastases of colorectal cancer in living rats.

scientific article published on 27 March 2003

Imaging transgene activity in vivo.

scientific article

In vivo 19F magnetic resonance spectroscopy and chemical shift imaging of tri-fluoro-nitroimidazole as a potential hypoxia reporter in solid tumors

scientific article published on 01 June 2007

In vivo 31P MR spectral patterns and reproducibility in cancer patients studied in a multi-institutional trial.

scientific article published on June 2006

In vivo 5-fluorouracil and fluoronucleotide T1 relaxation time measurements using the variable nutation angle method

scientific article published in July 2004

In vivo detection by 31P NMR of pentose phosphate pathway block secondary to biochemical modulation

scientific article published on 01 May 1996

In vivo measurements of bone marrow cellularity using volume-localized proton NMR spectroscopy.

scientific article published in May 1991

In vivo multiple-mouse imaging at 1.5 T.

scientific article published in March 2003

In vivo tumor lactate relaxation measurements by selective multiple-quantum-coherence (Sel-MQC) transfer

scientific article

Inhibition of prostate cancer proliferation by Deferiprone.

scientific article

Investigation of native fluorescence spectral difference among prostate cancer cell lines with different risk levels

Iron deposition is associated with differential macrophage infiltration and therapeutic response to iron chelation in prostate cancer

scientific article published on 14 September 2017

Iron imaging reveals tumor and metastasis macrophage hemosiderin deposits in breast cancer

scientific article published on 12 September 2017

J-difference lactate editing at 3.0 Tesla in the presence of strong lipids

scientific article

LDH-A regulates the tumor microenvironment via HIF-signaling and modulates the immune response

scientific article published in PLoS ONE

Lactate Dehydrogenase A Depletion Alters MyC-CaP Tumor Metabolism, Microenvironment, and CAR T Cell Therapy

scientific article published on 21 July 2020

Lactate is a mediator of metabolic cooperation between stromal carcinoma associated fibroblasts and glycolytic tumor cells in the tumor microenvironment.

scientific article

Liver regeneration in humans is characterized by significant changes in cellular phosphorus metabolism: assessment using proton-decoupled 31P-magnetic resonance spectroscopic imaging

scientific article published in August 2005

MRI of mouse models for gliomas shows similarities to humans and can be used to identify mice for preclinical trials

scientific article published on November 2002

Magnetic resonance spectroscopy and clinical cancer prognosis

scientific article published in April 2004

Magnetic resonance spectroscopy and imaging in radiology

scientific article published on November 1995

Mapping Tumor Hypoxia In Vivo Using Pattern Recognition of Dynamic Contrast-enhanced MRI Data

scientific article

Measurements of tumor tissue oxygen tension using a time-resolved luminescence-based optical oxylite probe: comparison with a paired survival assay

scientific article published in August 2002

Metabolic imaging: a link between lactate dehydrogenase A, lactate, and tumor phenotype

scientific article

Metabolic plasticity of metastatic breast cancer cells: adaptation to changes in the microenvironment.

scientific article

Metabolic response of the CWR22 prostate tumor xenograft after 20 Gy of radiation studied by 1H spectroscopic imaging.

scientific article

Metabolic signatures associated with a NAD synthesis inhibitor-induced tumor apoptosis identified by 1H-decoupled-31P magnetic resonance spectroscopy

scientific article published in May 2005

Methodological standardization for a multi-institutional in vivo trial of localized 31P MR spectroscopy in human cancer research. In vitro and normal volunteer studies.

scientific article published in October 2004

Multimodality Registration without a Dedicated Multimodality Scanner

scientific article published on 01 March 2007

Murine S factors for liver, spleen, and kidney.

scientific article published in May 2003

Native fluorescence spectroscopy reveals spectral differences among prostate cancer cell lines with different risk levels

scientific article published on August 2013

Non-invasive imaging of angiogenesis in head and neck squamous cell carcinoma

scientific article

Non-invasive molecular and functional imaging of cytosine deaminase and uracil phosphoribosyltransferase fused with red fluorescence protein

scientific article

Noninvasive assessment of tumor microenvironment using dynamic contrast-enhanced magnetic resonance imaging and 18F-fluoromisonidazole positron emission tomography imaging in neck nodal metastases.

scientific article

Noninvasive multimodality imaging of the tumor microenvironment: registered dynamic magnetic resonance imaging and positron emission tomography studies of a preclinical tumor model of tumor hypoxia.

scientific article published on March 2009

Noninvasive phosphorus magnetic resonance spectroscopic imaging predicts outcome to first-line chemotherapy in newly diagnosed patients with diffuse large B-cell lymphoma

scientific article published on September 2013

Osteogenic and Ewing sarcomas: estimation of necrotic fraction during induction chemotherapy with dynamic contrast-enhanced MR imaging

scientific article published in July 2003

Pharmacokinetics and Biodistribution of (86)Y-Trastuzumab for (90)Y dosimetry in an ovarian carcinoma model: correlative MicroPET and MRI.

scientific article published in July 2003

Phosphorus Magnetic Resonance Spectroscopy Predicts Outcome to Chemotherapy In Patients with Diffuse Large B-Cell Lymphoma: A Prospective International Multicenter Analysis of a Pretreatment Metabolic Biomarker of Response ⬇️

scholarly article

Potentiation of a three drug chemotherapy regimen by radiation

scientific article published on 01 August 1993

Preclinical evaluation of tumor microvascular response to a novel antiangiogenic/antitumor agent RO0281501 by dynamic contrast-enhanced MRI at 1.5 T

scientific article published in August 2006

Preclinical study of treatment response in HCT-116 cells and xenografts with (1) H-decoupled (31) P MRS.

scientific article

Prediction of treatment response of head and neck cancers with P-31 MR spectroscopy from pretreatment relative phosphomonoester levels

scientific article published on 01 June 2002

Preliminary assessment of magnetic resonance spectroscopic imaging in predicting treatment outcome in patients with prostate cancer at high risk for relapse

scientific article published in December 2004

Prostate cancer: correlation of MR imaging and MR spectroscopy with pathologic findings after radiation therapy-initial experience

scientific article published on 21 June 2005

Prostate cancer: identification with combined diffusion-weighted MR imaging and 3D 1H MR spectroscopic imaging--correlation with pathologic findings

scientific article published on February 2008

Prostate tumor volume measurement with combined T2-weighted imaging and diffusion-weighted MR: correlation with pathologic tumor volume

scientific article published on August 2009

Proton MRS detects metabolic changes in hormone sensitive and resistant human prostate cancer models CWR22 and CWR22r

scientific article published on November 2009

Proton magnetic resonance spectroscopy in immunocompetent patients with primary central nervous system lymphoma.

scientific article published in January 2005

Pten dose dictates cancer progression in the prostate

scientific article

Quantitation of total metastatic tumor volume in the rat liver: correlation of MR and histologic measurements

scientific article published on 01 May 1992

Quantitative assessment of bone marrow hematopoiesis using parametric magnetic resonance imaging ⬇️

scientific article published on May 1, 1998

Radiation impairs perineural invasion by modulating the nerve microenvironment.

scientific article

Radiosynthesis of the tumor hypoxia marker [18F]TFMISO via O-[18F]trifluoroethylation reveals a striking difference between trifluoroethyl tosylate and iodide in regiochemical reactivity toward oxygen nucleophiles

scientific article

Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer

scientific article published on May 2011

Regarding the focal treatment of prostate cancer: inference of the Gleason grade from magnetic resonance spectroscopic imaging

scientific article published on 5 November 2008

Registration of planar bioluminescence to magnetic resonance and x-ray computed tomography images as a platform for the development of bioluminescence tomography reconstruction algorithms

scientific article

Relationship of changes in pH and energy status to hypoxic cell fraction and hyperthermia sensitivity

Relationships between LDH-A, lactate, and metastases in 4T1 breast tumors.

scientific article published on 05 July 2013

Resolution enhanced NMR spectroscopy in biological systems via magnetic susceptibility matched sample immersion chambers

scientific article published on 01 December 1993

Response of HT29 colorectal xenograft model to cediranib assessed with 18 F-fluoromisonidazole positron emission tomography, dynamic contrast-enhanced and diffusion-weighted MRI.

scientific article

Semi-automatic deformable registration of prostate MR images to pathological slices

scientific article

Serial measurement of hepatic lipids during chemotherapy in patients with colorectal cancer: a 1 H MRS study

scientific article

Single-dose radiotherapy disables tumor cell homologous recombination via ischemia/reperfusion injury

Spatial mapping of the percentage cellularity in human bone marrow using magnetic resonance imaging.

scientific article published on February 1996

Targeted elimination of prostate cancer by genetically directed human T lymphocytes

scientific article

Temporal/spatial resolution improvement of in vivo DCE-MRI with compressed sensing-optimized FLASH

scientific article

The utility of magnetic resonance imaging and spectroscopy for predicting insignificant prostate cancer: an initial analysis

article

Therapeutic strategy for acute spinal cord contusion injury: cell elimination combined with microsurgical intervention ⬇️

scientific article

Transition zone prostate cancer: metabolic characteristics at 1H MR spectroscopic imaging--initial results

scientific article published on 14 August 2003

Tumor metabolism and perfusion in head and neck squamous cell carcinoma: pretreatment multimodality imaging with 1H magnetic resonance spectroscopy, dynamic contrast-enhanced MRI, and [18F]FDG-PET.

scientific article

Tumor stroma interaction is mediated by monocarboxylate metabolism.

scientific article published on 26 January 2017

Understanding the pharmacological properties of a metabolic PET tracer in prostate cancer

scientific article

VEGF expression in osteosarcoma correlates with vascular permeability by dynamic MRI

scientific article published in September 2004

Visualizing the antivascular effect of bortezomib on the hypoxic tumor microenvironment

scientific article published on 23 September 2015

mTOR promotes survival and astrocytic characteristics induced by Pten/AKT signaling in glioblastoma

scientific article published on April 2005

β4 Integrin signaling induces expansion of prostate tumor progenitors

scientific article published on 25 January 2013

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