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List of works by Michael Hummel

A Mouse Model of CMV Transmission Following Kidney Transplantation ⬇️

scientific article published on January 6, 2012

A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling

scientific article published in June 2006

A membrane protein encoded by Epstein-Barr virus in latent growth-transforming infection ⬇️

scientific article published on November 1, 1984

A modular transcriptome map of mature B cell lymphomas

article

A new method to prevent carry-over contaminations in two-step PCR NGS library preparations

scientific article published on 7 July 2015

A novel approach to detect resistance mechanisms reveals FGR as a factor mediating HDAC inhibitor SAHA resistance in B-cell lymphoma

scientific article published on 9 June 2016

A novel fusion of the MALT1 gene and the microtubule-associated protein 4 (MAP4) gene occurs in diffuse large B-cell lymphoma

scientific article published on 01 September 2006

A novel interleukin-12 p40-related protein induced by latent Epstein-Barr virus infection in B lymphocytes

scientific article

A recurrent 11q aberration pattern characterizes a subset of MYC-negative high-grade B-cell lymphomas resembling Burkitt lymphoma

scientific article

A roadmap of constitutive NF-κB activity in Hodgkin lymphoma: Dominant roles of p50 and p52 revealed by genome-wide analyses.

scientific article published on 17 March 2016

Aberrant expression of Notch1 interferes with the B-lymphoid phenotype of neoplastic B cells in classical Hodgkin lymphoma.

scientific article

Activity-based probes for detection of active MALT1 paracaspase in immune cells and lymphomas

scientific article

Advanced patient age at diagnosis of diffuse large B-cell lymphoma is associated with molecular characteristics including ABC-subtype and high expression of MYC.

scientific article published on 25 August 2017

Age and cellular composition influence overall survival in a collective of non-immunocompromised patients with EBV-positive diffuse large B-cell lymphoma from a German lymphoma center

scientific article published on 27 April 2016

Algorithms for differential splicing detection using exon arrays: a comparative assessment

scientific article

Allogeneic transplantation induces expression of cytomegalovirus immediate-early genes in vivo: a model for reactivation from latency

scientific article

Alterations of microRNA and microRNA-regulated messenger RNA expression in germinal center B-cell lymphomas determined by integrative sequencing analysis

scientific article

An Epstein-Barr virus DNA fragment encodes messages for the two major envelope glycoproteins (gp350/300 and gp220/200)

scientific article published on February 1984

Biological characterization of adult MYC-translocation-positive mature B-cell lymphomas other than molecular Burkitt lymphoma

scientific article

Burkitt's and Burkitt-like lymphoma. Molecular definition and value of the World Health Organisation's diagnostic criteria

scientific article published in February 2007

CD30-induced signaling is absent in Hodgkin's cells but present in anaplastic large cell lymphoma cells

scientific article published on 10 January 2008

Cellular Localization of Latent Murine Cytomegalovirus ⬇️

scientific article published on January 1, 1998

Characterization of genomic imbalances in diffuse large B-cell lymphoma by detailed SNP-chip analysis

scientific article published on 22 July 2014

Classical Hodgkin lymphoma is characterized by high constitutive expression of activating transcription factor 3 (ATF3), which promotes viability of Hodgkin/Reed-Sternberg cells

scientific article

Classical Hodgkin's disease and follicular lymphoma originating from the same germinal center B cell

scientific article published on December 1999

Classical Hodgkin's lymphoma shows epigenetic features of abortive plasma cell differentiation ⬇️

scientific article published on March 10, 2011

Classification and pathogenesis of malignant lymphomas

scientific article published in April 2007

Clinical Impact of the Cell-of-Origin Classification and the MYC/ BCL2 Dual Expresser Status in Diffuse Large B-Cell Lymphoma Treated Within Prospective Clinical Trials of the German High-Grade Non-Hodgkin's Lymphoma Study Group

scientific article published on 19 May 2017

Clonal T cell receptor gamma-chain gene rearrangement by PCR-based GeneScan analysis in the skin and blood of patients with parapsoriasis and early-stage mycosis fungoides

scientific article published on 01 July 2002

Cloning and expression of an inhibitor of microbial metalloproteinases from insects contributing to innate immunity

scientific article published on August 2004

Common clonal T-cell origin in a patient with T-prolymphocytic leukaemia and associated cutaneous T-cell lymphomas.

scientific article

Common clonal origin of an acute B-lymphoblastic leukemia and a Langerhans' cell sarcoma: evidence for hematopoietic plasticity

scientific article published on 26 April 2010

Comparative assessment of differential network analysis methods

scientific article published on 29 July 2016

Comprehensive Metaboproteomics of Burkitt's and Diffuse Large B-Cell Lymphoma Cell Lines and Primary Tumor Tissues Reveals Distinct Differences in Pyruvate Content and Metabolism

scientific article published on 06 February 2017

Cutaneous T cell lymphoma and classic Hodgkin lymphoma of the B cell type within a single lymph node: composite lymphoma

scientific article published on March 2004

Cutaneous involvement in prelymphomatous angioimmunoblastic lymphadenopathy

scientific article published on 01 February 1997

DCLRE1C (ARTEMIS) mutations causing phenotypes ranging from atypical severe combined immunodeficiency to mere antibody deficiency.

scientific article

Deep Sequencing of MYC DNA-Binding Sites in Burkitt Lymphoma ⬇️

scientific article published on November 10, 2011

Defective octamer-dependent transcription is responsible for silenced immunoglobulin transcription in Reed-Sternberg cells.

scientific article published on May 2001

Derepression of an endogenous long terminal repeat activates the CSF1R proto-oncogene in human lymphoma

scientific article published on 2 May 2010

Detection of genomic aberrations in molecularly defined Burkitt's lymphoma by array-based, high resolution, single nucleotide polymorphism analysis

scientific article

Different biological risk factors in young poor-prognosis and elderly patients with diffuse large B-cell lymphoma

scientific article

Differential micro-RNA expression in primary CNS and nodal diffuse large B-cell lymphomas ⬇️

scientific article published on July 29, 2011

Differential regulation of miR-21 and miR-146a by Epstein-Barr virus-encoded EBNA2.

scientific article published on 19 April 2012

Donor CD4 T Cell Diversity Determines Virus Reactivation in Patients After HLA-Matched Allogeneic Stem Cell Transplantation

scientific article

Early TCR-beta and TCR-gamma PCR detection of T-cell clonality indicates minimal tumor disease in lymph nodes of cutaneous T-cell lymphoma: diagnostic and prognostic implications

scientific article published on 30 September 2004

Effect of ionizing radiation on cellular procoagulability and co-ordinated gene alterations

scientific article

Epigenetic silencing of the immunoglobulin heavy-chain gene in classical Hodgkin lymphoma-derived cell lines contributes to the loss of immunoglobulin expression

scientific article published on 29 July 2004

Epstein-Barr virus RNA. VIII. Viral RNA in permissively infected B95-8 cells ⬇️

scientific article published on July 1, 1982

Epstein-Barr virus in Kikuchi-Fujimoto disease

scientific article published in April 1993

Epstein-Barr virus infection in Western European pediatric non-Hodgkin lymphomas ⬇️

scientific article published on December 1, 2003

Epstein-Barr virus-associated Hodgkin's disease: epidemiologic characteristics in international data.

scientific article published on February 1997

Epstein-barr virus infection of monocytoid B-cell proliferates: an early feature of primary viral infection?

scientific article published in May 2005

FOXM1: A novel drug target in gastroenteropancreatic neuroendocrine tumors

scientific article

Frequency of clonal intraepithelial T lymphocyte proliferations in enteropathy-type intestinal T cell lymphoma, coeliac disease, and refractory sprue ⬇️

scientific article published on December 1, 2001

Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphoma

scientific article published on 26 September 2016

Frequent expression of the B-cell-specific activator protein in Reed-Sternberg cells of classical Hodgkin's disease provides further evidence for its B-cell origin

scientific article published on 01 November 1999

Gain of chromosome region 18q21 including the MALT1 gene is associated with the activated B-cell-like gene expression subtype and increased BCL2 gene dosage and protein expression in diffuse large B-cell lymphoma

scientific article published on 26 March 2008

Gene deregulation and spatial genome reorganization near breakpoints prior to formation of translocations in anaplastic large cell lymphoma

scholarly article

Gene expression profiling reveals a close relationship between follicular lymphoma grade 3A and 3B, but distinct profiles of follicular lymphoma grade 1 and 2.

scientific article published on 22 March 2018

Global gene expression changes of in vitro stimulated human transformed germinal centre B cells as surrogate for oncogenic pathway activation in individual aggressive B cell lymphomas

scientific article published on 20 December 2012

Heterogeneous Epstein-Barr virus infection patterns in peripheral T-cell lymphoma of angioimmunoblastic lymphadenopathy type

scientific article (publication date: October 1992)

High myc activity is an independent negative prognostic factor for diffuse large B cell lymphomas ⬇️

scientific article published on October 23, 2011

Histone acetylation and DNA demethylation of B cells result in a Hodgkin-like phenotype

scientific article published on 7 February 2008

Histone acetylation and DNA demethylation of T cells result in an anaplastic large cell lymphoma-like phenotype ⬇️

scientific article published on August 16, 2012

Histopathological features and their prognostic impact in nodular lymphocyte-predominant Hodgkin lymphoma--a matched pair analysis from the German Hodgkin Study Group (GHSG).

scientific article published on 26 June 2014

Hypermutation of the inactive X chromosome is a frequent event in cancer

scientific article published on 17 October 2013

Identification of ADGRE5 as discriminating MYC target between Burkitt lymphoma and diffuse large B-cell lymphoma

scholarly article by Karsten Kleo et al published 5 April 2019 in BMC Cancer

Identification of polypeptide components of the Epstein-Barr virus early antigen complex with monoclonal antibodies ⬇️

scientific article published on July 1, 1983

Ig rearrangements in isolated Reed-Sternberg cells: conclusions from four different studies

scientific article published on January 1996

Immune modulation by non-hodgkin lymphoma in a patient with two primary intestinal T-cell lymphomas and long-standing celiac disease

scientific article published on 29 January 2010

Immunoblastic morphology but not the immunohistochemical GCB/nonGCB classifier predicts outcome in diffuse large B-cell lymphoma in the RICOVER-60 trial of the DSHNHL.

scientific article published on 24 August 2010

Immunoglobulin receptor evolution in follicular lymphoma and a review of literature

scientific article published on 01 October 2007

Immunosuppression is not required for reactivation of latent murine cytomegalovirus

scientific article published on 01 February 1999

Inactivating I kappa B epsilon mutations in Hodgkin/Reed-Sternberg cells

scientific article

Influence of antigen on the development of MALT lymphoma

scientific article published on 4 October 2005

Intestinal T-cell lymphoma: a reassessment of cytomorphological and phenotypic features in relation to patterns of small bowel remodelling

scientific article published on September 1996

Intratumoral morphological heterogeneity can be an indicator of genetic heterogeneity in colorectal cancer

scientific article published on 11 January 2018

IκB-ζ controls the constitutive NF-κB target gene network and survival of ABC DLBCL

scientific article

Loss of HLA-DR expression and immunoblastic morphology predict adverse outcome in diffuse large B-cell lymphoma - analyses of cases from two prospective randomized clinical trials

scientific article

Low frequency of p53 gene mutation and protein expression in mucinous colorectal carcinomas

scientific article published on 01 June 1996

MINCR is a MYC-induced lncRNA able to modulate MYC's transcriptional network in Burkitt lymphoma cells

scientific article

MYC status in concert with BCL2 and BCL6 expression predicts outcome in diffuse large B-cell lymphoma ⬇️

scientific article published on January 18, 2013

Macrophage development from HSCs requires PU.1-coordinated microRNA expression.

scientific article published on 5 July 2011

Mapping of polypeptides encoded by the Epstein-Barr virus genome in productive infection

scientific article

Mapping of transcription factor motifs in active chromatin identifies IRF5 as key regulator in classical Hodgkin lymphoma

scientific article

Massive transcriptional perturbation in subgroups of diffuse large B-cell lymphomas

scientific article

MicroRNA‐142 is mutated in about 20% of diffuse large B‐cell lymphoma ⬇️

scientific article published on September 18, 2012

Microarray-based genomic profiling reveals novel genomic aberrations in follicular lymphoma which associate with patient survival and gene expression status

article

Molecular profiles and clinical outcome of stage UICC II colon cancer patients

scientific article published on 05 April 2011

Molecular profiling of pediatric mature B-cell lymphoma treated in population-based prospective clinical trials

scientific article published on 28 May 2008

Multicenter validation of cancer gene panel-based next-generation sequencing for translational research and molecular diagnostics.

scientific article

Mutational frequencies of CD79B and MYD88 vary greatly between primary testicular DLBCL and gastrointestinal DLBCL.

scientific article published on 3 September 2017

New insights into the biology and origin of mature aggressive B-cell lymphomas by combined epigenomic, genomic, and transcriptional profiling

scientific article

Novel IGH and MYC Translocation Partners in Diffuse Large B-Cell Lymphomas

scientific article published on 29 June 2016

Nucleotide sequences of mRNAs encoding Epstein-Barr virus nuclear proteins: a probable transcriptional initiation site

scientific article published on July 1986

Opposing roles of NF-κB in anti-cancer treatment outcome unveiled by cross-species investigations

scientific article

Origin of primary gastric T-cell lymphomas from intraepithelial T-lymphocytes: report of two cases

scientific article published on 01 January 1999

PAX5 overexpression is not enough to reestablish the mature B-cell phenotype in classical Hodgkin lymphoma

scientific article published on 11 July 2013

PTEN loss defines a PI3K/AKT pathway-dependent germinal center subtype of diffuse large B-cell lymphoma

scientific article published on 09 July 2013

Pathway activation patterns in diffuse large B-cell lymphomas.

scientific article

Patient age at diagnosis is associated with the molecular characteristics of diffuse large B-cell lymphoma

scientific article published on 11 January 2012

Poorly Differentiated Medullary Phenotype Predicts Poor Survival in Early Lymph Node-Negative Gastro-Esophageal Adenocarcinomas

scientific article

Procarbazine-free OEPA-COPDAC chemotherapy in boys and standard OPPA-COPP in girls have comparable effectiveness in pediatric Hodgkin's lymphoma: the GPOH-HD-2002 study

scientific article

Proximal weakness in a patient with MALT lymphoma: a case report and discussion of possible pathogenesis.

scientific article published on 19 May 2015

RIP1 expression is necessary for CD30-mediated cell death induction in anaplastic large-cell lymphoma cells ⬇️

scientific article published on April 1, 2013

RNA encoded by the IR1-U2 region of Epstein-Barr virus DNA in latently infected, growth-transformed cells ⬇️

scientific article published on May 1, 1983

Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing

scientific article

Refractory human papillomavirus-associated oral warts treated topically with 1-3% cidofovir solutions in human immunodeficiency virus type 1-infected patients

scientific article published in March 2005

Refractory sprue syndrome with clonal intraepithelial lymphocytes evolving into overt enteropathy-type intestinal T-cell lymphoma

scientific article published in January 2000

Report: workshop on mediastinal grey zone lymphoma

scientific article published in July 2005

Report: workshop on mediastinal grey zone lymphoma

article by Sibrand Poppema et al published 6 June 2005 in European Journal of Haematology

Silencing of APAF-1 in B-CLL results in poor prognosis in the case of concomitant p53 mutation

scientific article published in May 2006

Similar clinical features in follicular lymphomas with and without breaks in the BCL2 locus.

scientific article published on December 2015

Single-cell analysis of CD30+ cells in lymphomatoid papulosis demonstrates a common clonal T-cell origin

scientific article published on 01 July 2002

Synergy of interleukin 10 and toll-like receptor 9 signalling in B cell proliferation: Implications for lymphoma pathogenesis.

scientific article published on 26 September 2016

Synthetic lethal metabolic targeting of cellular senescence in cancer therapy.

scientific article published on 14 August 2013

T-cell clonality of undetermined significance

scientific article published on 01 July 2001

T-cell clonality of undetermined significance

scientific article published on 01 March 2006

The AP-1-BATF and -BATF3 module is essential for growth, survival and TH17/ILC3 skewing of anaplastic large cell lymphoma.

scientific article published on 28 March 2018

The IL-15 cytokine system provides growth and survival signals in Hodgkin lymphoma and enhances the inflammatory phenotype of HRS cells

scientific article published on 9 December 2014

The PCBP1 gene encoding poly(rC) binding protein I is recurrently mutated in Burkitt lymphoma

scientific article published on 14 July 2015

The different epidemiologic subtypes of Burkitt lymphoma share a homogenous micro RNA profile distinct from diffuse large B-cell lymphoma

scientific article published on 24 June 2011

The diversity of rearranged immunoglobulin heavy chain variable region genes in peripheral blood B cells of preterm infants is restricted by short third complementarity-determining regions but not by limited gene segment usage

scientific article (publication date: March 2001)

The glucosinolate metabolite 1-methoxy-3-indolylmethyl alcohol induces a gene expression profile in mouse liver similar to the expression signature caused by known genotoxic hepatocarcinogens.

scientific article published on 9 February 2015

The prognostic impact of variant histology in nodular lymphocyte-predominant Hodgkin lymphoma: a report from the German Hodgkin Study Group (GHSG)

scientific article published on 07 October 2013

Three coexisting lymphomas in one patient: genetically related or only a coincidence?

scientific article published on December 2006

Transition of Sézary syndrome into mycosis fungoides after complete clinical and molecular remission under extracorporeal photophoresis

scientific article

Translocations activating IRF4 identify a subtype of germinal center-derived B-cell lymphoma affecting predominantly children and young adults

scientific article published on 12 April 2011

Uniform Expression of Cytotoxic Molecules in Anaplastic Large Cell Lymphoma of Null/T Cell Phenotype and in Cell Lines Derived from Anaplastic Large Cell Lymphoma ⬇️

scientific article published on January 1, 1997

Unusual relapse of an angioimmunoblastic T cell lymphoma 11 years after initial manifestation

Validation and comparison of two NGS assays for the detection of EGFR T790M resistance mutation in liquid biopsies of NSCLC patients

scientific article published on 6 April 2018

[Chances and risks of blood-based molecular pathological analysis of circulating tumor cells (CTC) and cell-free DNA (cfDNA) in personalized cancer therapy: positional paper from the study group on liquid biopsy of the working group for molecular pa

scientific article published in February 2015

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