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List of works by Adrian J Wolstenholme

120nm resolution in thick samples with structured illumination and adaptive optics

2-Aminoethoxydiphenylborane is an acute inhibitor of directly photosensitive retinal ganglion cell activity in vitro and in vivo.

scientific article published on April 2007

ACR-26: a novel nicotinic receptor subunit of parasitic nematodes.

scientific article

Altered avr-14B gene transcription patterns in ivermectin-resistant isolates of the cattle parasites, Cooperia oncophora and Ostertagia ostertagi ⬇️

scientific article published on August 1, 2011

Altered drug resistance and recovery from paralysis in Drosophila melanogaster with a deficient histamine-gated chloride channel

scientific article published in October 2002

Altered ivermectin pharmacology and defective visual system in Drosophila mutants for histamine receptor HCLB.

scientific article published on 7 October 2008

Alternative splicing of a Caenorhabditis elegans gene produces two novel inhibitory amino acid receptor subunits with identical ligand binding domains but different ion channels ⬇️

scientific article published on November 12, 1997

An ivermectin-sensitive glutamate-gated chloride channel from the parasitic nematode Haemonchus contortus

scientific article published on 31 March 2009

An ivermectin-sensitive glutamate-gated chloride channel subunit from Dirofilaria immitis.

scientific article

Anthelmintics - From Discovery to Resistance III (Indian Rocks Beach, FL, 2018)

scientific article published on 05 November 2018

Anthelmintics - from discovery to resistance

scientific article

Anthelmintics: From discovery to resistance II (San Diego, 2016)

scientific article

Caenorhabditis elegans ivermectin receptors regulate locomotor behaviour and are functional orthologues of Haemonchus contortus receptors

scientific article published on 24 February 2006

Candidate anthelmintic resistance-associated gene expression and sequence polymorphisms in a triple-resistant field isolate of Haemonchus contortus.

scientific article published on 16 September 2011

Characterization of a nicotinic acetylcholine receptor from the insect Manduca sexta ⬇️

scientific article published on March 1, 1998

Characterization of the Ca2+-gated and voltage-dependent K+-channel Slo-1 of nematodes and its interaction with emodepside

scientific article (publication date: December 2014)

Cloning of a putative inhibitory amino acid receptor subunit from the parasitic nematode Haemonchus contortus

scientific article published on January 1, 1994

Comparative sequences of the Wolbachia genomes of drug-sensitive and resistant isolates of Dirofilaria immitis

scientific article published on 05 September 2020

Deciphering the molecular determinants of cholinergic anthelmintic sensitivity in nematodes: When novel functional validation approaches highlight major differences between the model Caenorhabditis elegans and parasitic species.

scientific article published on 2 May 2018

Detection and measurement of benzimidazole resistance alleles in Haemonchus contortus using real-time PCR with locked nucleic acid Taqman probes

scientific article published on 28 November 2006

Development of an in vitro bioassay for measuring susceptibility to macrocyclic lactone anthelmintics in Dirofilaria immitis

scientific article published on 6 June 2013

Dirofilaria immitis: identification of a novel ligand-gated ion channel-related polypeptide

scientific article

Distribution of glutamate-gated chloride channel subunits in the parasitic nematode Haemonchus contortus

scientific article

Does evaluation of in vitro microfilarial motility reflect the resistance status of Dirofilaria immitis isolates to macrocyclic lactones?

scientific article published on 9 November 2017

Drug resistance in veterinary helminths

scientific article published in October 2004

EAT-18 is an essential auxiliary protein interacting with the non-alpha nAChR subunit EAT-2 to form a functional receptor

scientific article published on 03 April 2020

Efficacy and side effects of doxycycline versus minocycline in the three-dose melarsomine canine adulticidal heartworm treatment protocol

scholarly article published by Molly D Savadelis in 2018

Enhanced resolution through thick tissue with structured illumination and adaptive optics

scientific article published on February 2015

Evaluation of the in vitro susceptibility of various filarial nematodes to emodepside

scientific article published on 28 July 2021

Evaluation of the larval migration inhibition assay for detecting macrocyclic lactone resistance in Dirofilaria immitis.

scientific article published on 8 September 2017

Evolution. Surviving in a toxic world

scientific article published on February 2012

Expression of nicotinic acetylcholine receptor subunits from parasitic nematodes in Caenorhabditis elegans

scientific article

Expression of wild-type and mutated Drosophila melanogaster xanthine dehydrogenases in Aspergillus nidulans ⬇️

scientific article published on August 1, 1997

FGT-1 is the major glucose transporter in C. elegans and is central to aging pathways

scientific article published on December 2013

Frontiers in parasite neurobiology: parasite genomics, neural signalling and new targets for control

scientific article published on 01 December 2007

Functional Characterization of a Novel Class of Morantel-Sensitive Acetylcholine Receptors in Nematodes

scientific article

Functional consequences of mutations in the Drosophila histamine receptor HCLB.

scientific article published on January 2010

Global Change and Helminth Infections in Grazing Ruminants in Europe: Impacts, Trends and Sustainable Solutions

scientific article published on 26 August 2013

Glutamate-gated Chloride Channels ⬇️

scientific article published on October 4, 2012

Glutamate-gated Cl- channels in Caenorhabditis elegans and parasitic nematodes ⬇️

scientific article published on August 1, 1997

Glutamate-gated chloride channels of Haemonchus contortus restore drug sensitivity to ivermectin resistant Caenorhabditis elegans

scientific article

How do the macrocyclic lactones kill filarial nematode larvae?

scientific article

Human Leukocytes Kill Brugia malayi Microfilariae Independently of DNA-Based Extracellular Trap Release.

scientific article

Human peripheral blood mononuclear cells express GABAA receptor subunits.

scientific article published on 4 October 2005

Immunocytochemical localization of a putative inhibitory amino acid receptor subunit in the parasitic nematodes Haemonchus contortus and Ascaris suum ⬇️

scientific article published on July 1, 1998

Increasing the expression of calcium-permeable TRPC3 and TRPC7 channels enhances constitutive secretion

scientific journal article

Ion channels and receptor as targets for the control of parasitic nematodes

scientific article published on 14 October 2011

Ivermectin-dependent attachment of neutrophils and peripheral blood mononuclear cells to Dirofilaria immitis microfilariae in vitro.

scientific article published on 12 February 2014

Macrocyclic lactone anthelmintic-induced leukocyte binding to Dirofilaria immitis microfilariae: Influence of the drug resistance status of the parasite

scientific article published on 26 April 2019

Molecular basis for convergent evolution of glutamate recognition by pentameric ligand-gated ion channels

scientific article published on 24 February 2015

Nematode parasite genes: what's in a name?

scientific article published on 17 May 2010

Phylogenetic shadowing of a histamine-gated chloride channel involved in insect vision

scientific article published on 25 October 2005

Recent advances in candidate-gene and whole-genome approaches to the discovery of anthelmintic resistance markers and the description of drug/receptor interactions.

scientific article

Recent progress in understanding the interaction between avermectins and ligand-gated ion channels: putting the pests to sleep ⬇️

scientific article published on October 15, 2010

Recognition and killing of Brugia malayi microfilariae by human immune cells is dependent on the parasite sample and is not altered by ivermectin treatment

scientific article published on 22 September 2018

Refugia and anthelmintic resistance: Concepts and challenges

scientific article published on 17 May 2019

Resistance to macrocyclic lactones

scientific article published on May 2012

Sequence and level of endogenous expression of calcium channel beta subunits in Schistosoma mansoni displaying different susceptibilities to praziquantel

scientific article published in August 2003

Structure-activity studies of bicyclic and tricyclic analogues of methyllycaconitine ⬇️

scientific article published on August 1, 1997

TRP channels in parasites

scientific article published on January 2011

The avermectin receptors of Haemonchus contortus and Caenorhabditis elegans.

scientific article

The cys-loop ligand-gated ion channel gene family of Brugia malayi and Trichinella spiralis: a comparison with Caenorhabditis elegans.

scientific article

The emergence of macrocyclic lactone resistance in the canine heartworm, Dirofilaria immitis

scientific article published on 04 June 2015

The genome and transcriptome of Haemonchus contortus, a key model parasite for drug and vaccine discovery

scientific article

The genome of the heartworm, Dirofilaria immitis, reveals drug and vaccine targets

scientific article

The nicotinic acetylcholine receptors of the parasitic nematode Ascaris suum: formation of two distinct drug targets by varying the relative expression levels of two subunits

scientific article

Transcription and replication of influenza virus RNA

scientific article published on October 15, 1979

Transient effects of levamisole on Brugia malayi microfilariae.

scientific article published on 18 July 2015

Using population genetics to examine relationships of Dirofilaria immitis based on both macrocyclic lactone-resistance status and geography

scientific article published on 23 May 2020

Utilization of computer processed high definition video imaging for measuring motility of microscopic nematode stages on a quantitative scale: "The Worminator".

scientific article

Xanthine oxidoreductase in human mammary epithelial cells: activation in response to inflammatory cytokines ⬇️

scientific article published on July 23, 1998

Xanthine oxidoreductase: dehydrogenase to oxidase conversion ⬇️

scientific article published on 01 August 1997

Xenopus laevis RIC-3 enhances the functional expression of the C. elegans homomeric nicotinic receptor, ACR-16, in Xenopus oocytes.

scientific article

Zinc binding by retroviral integrase

scientific article published on December 15, 1992

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