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List of works by Sascha Weggen

A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity

scientific article published on November 8, 2001

APP dimer formation is initiated in the endoplasmic reticulum and differs between APP isoforms

scientific article published on November 22, 2011

Amyloid precursor-like protein 1 accumulates in neuritic plaques in Alzheimer's disease

scientific article published on December 1, 1997

Autoreactive‐Aβ antibodies promote APP β‐secretase processing

scientific article published on January 23, 2012

Discovery and Biological Evaluation of Potent and Selective N-Methylene Saccharin-Derived Inhibitors for Rhomboid Intramembrane Proteases.

scientific article published on 29 November 2017

LRP1 is critical for the surface distribution and internalization of the NR2B NMDA receptor subtype

scientific article published on July 17, 2013

No improvement after chronic ibuprofen treatment in the 5XFAD mouse model of Alzheimer's disease

scientific article published on September 22, 2011

Presenilin Is the Molecular Target of Acidic γ-Secretase Modulators in Living Cells

scientific article published on January 6, 2012

Presenilin-1 but not amyloid precursor protein mutations present in mouse models of Alzheimer’s disease attenuate the response of cultured cells to γ-secretase modulators regardless of their potency and structure

scientific article published on December 13, 2010

SAR studies of acidic dual γ-secretase/PPARγ modulators

scientific article published on August 6, 2011

Stx5 is a novel interactor of VLDL-R to affect its intracellular trafficking and processing

scientific article published on May 20, 2013

Substrate sequence influences γ-secretase modulator activity, role of the transmembrane domain of the amyloid precursor protein

scientific article published on August 25, 2011

Synthesis of a potent photoreactive acidic γ-secretase modulator for target identification in cells

scientific article published on August 31, 2012

The metalloprotease ADAMTS4 generates N-truncated Aβ4-x species and marks oligodendrocytes as a source of amyloidogenic peptides in Alzheimer's disease

scientific article published on 13 November 2018