List of works by Jay T Groves

A Mechanism for Tunable Autoinhibition in the Structure of a Human Ca2+/Calmodulin- Dependent Kinase II Holoenzyme

scientific article

A Microbead Supported Membrane-Based Fluorescence Imaging Assay Reveals Intermembrane Receptor-Ligand Complex Dimension with Nanometer Precision.

scientific article published on 4 June 2016

A chemical approach to unraveling the biological function of the glycosylphosphatidylinositol anchor.

scholarly article

A fluid membrane-based soluble ligand-display system for live-cell assays

scientific article published on March 2006

A molecular assembly phase transition and kinetic proofreading modulate Ras activation by SOS.

scientific article published on 7 March 2019

A nanocube plasmonic sensor for molecular binding on membrane surfaces

scientific article published on May 2009

Activation-triggered subunit exchange between CaMKII holoenzymes facilitates the spread of kinase activity

scientific article published on January 2013

Allosteric Modulation of Grb2 Recruitment to the Intrinsically Disordered Scaffold Protein, LAT, by Remote Site Phosphorylation.

scientific article published on 28 November 2017

Altered TCR signaling from geometrically repatterned immunological synapses

scientific article published in November 2005

Altered actin centripetal retrograde flow in physically restricted immunological synapses

scientific article (publication date: 2010)

Analysis of shape, fluctuations, and dynamics in intermembrane junctions

scientific article

Architecture and function of membrane proteins in planar supported bilayers: a study with photosynthetic reaction centers

scientific article published on 01 November 1996

Author Correction: Single-cell analysis of EphA clustering phenotypes to probe cancer cell heterogeneity

scientific article published on 07 September 2020

Author Correction: Single-cell analysis of EphA clustering phenotypes to probe cancer cell heterogeneity

scientific article published on 06 November 2020

Bending mechanics and molecular organization in biological membranes

scientific article published on January 2007

Breakage of the oligomeric CaMKII hub by the regulatory segment of the kinase

scientific article published on 09 September 2020

Cell membrane array fabrication and assay technology

scientific article

Cell membranes: Glycans' imprints

scientific article published in February 2013

Characterization of dynamic actin associations with T-cell receptor microclusters in primary T cells.

scientific article

Chemistry. Unveiling the membrane domains

scientific article

Chiral discrimination in two dimensions

scientific article published on April 1996

Cholesterol-Enriched Domain Formation Induced by Viral-Encoded, Membrane-Active Amphipathic Peptide.

scientific article published on January 2016

Cluster size regulates protein sorting in the immunological synapse

scientific article

Colorimetric bio-barcode amplification assay for cytokines.

scientific article

Conformational coupling across the plasma membrane in activation of the EGF receptor

scientific article

Control of antigen presentation with a photoreleasable agonist peptide

scientific article published in December 2006

Correction: Activation-triggered subunit exchange between CaMKII holoenzymes facilitates the spread of kinase activity

scientific article published on 11 February 2014

Correlation of a dynamic model for immunological synapse formation with effector functions: two pathways to synapse formation.

scientific article

Coupled Membrane Lipid Miscibility and Phosphotyrosine-Driven Protein Condensation Phase Transitions

scientific article published on 24 September 2020

Coupled membrane fluctuations and protein mobility in supported intermembrane junctions

scientific article published in April 2006

Covalent Ras Dimerization on Membrane Surfaces through Photosensitized Oxidation.

scientific article published on 26 January 2016

Curvature and spatial organization in biological membranes

scientific article published in 2007

Curvature-modulated phase separation in lipid bilayer membranes

scientific article published in May 2006

DNA-mediated assembly of protein heterodimers on membrane surfaces

scientific article published on 26 March 2013

Detection of molecular interactions at membrane surfaces through colloid phase transitions

scientific article published in January 2004

Detection of proteins using a colorimetric bio-barcode assay

scientific article published in January 2007

Diffusion of GPI-anchored proteins is influenced by the activity of dynamic cortical actin.

scientific article

Direct single molecule measurement of TCR triggering by agonist pMHC in living primary T cells

scientific article published on 03 July 2013

Discrete arrays of liquid-crystal-supported proteolipid monolayers as phantom cell surfaces

scientific article published in August 2008

Dynamic Cellular Interactions with Extracellular Matrix Triggered by Biomechanical Tuning of Low-Rigidity, Supported Lipid Membranes.

scientific article published on 30 March 2017

Dynamic Organization of Myristoylated Src in the Live Cell Plasma Membrane

scientific article published on 15 January 2016

Dynamic Scaling Analysis of Molecular Motion within the LAT:Grb2:SOS Protein Network on Membranes

scientific article published in October 2017

E-cadherin junction formation involves an active kinetic nucleation process.

scientific article

EGFR family and Src family kinase interactions: mechanics matters?

scientific article published on 28 December 2017

Early T cell receptor signals globally modulate ligand:receptor affinities during antigen discrimination

scientific article published on 30 October 2017

Effect of support corrugation on silica xerogel--supported phase-separated lipid bilayers

scientific article

Electric field-induced concentration gradients in planar supported bilayers

scientific article published on November 1995

Electric field-induced critical demixing in lipid bilayer membranes

scientific article published on February 1998

Electric field-induced reorganization of two-component supported bilayer membranes

scientific article

Electrical manipulation of glycan-phosphatidyl inositol-tethered proteins in planar supported bilayers

scientific article published on November 1996

Electrical manipulation of supported lipid membranes by embedded electrodes

scientific article

Electrostatic readout of DNA microarrays with charged microspheres

scientific article

Electrostatically Driven Spatial Patterns in Lipid Membrane Composition

scientific article published on 22 July 2005

Engineering of a synthetic electron conduit in living cells ⬇️

scientific article published on October 18, 2010

Engineering supported membranes for cell biology

scientific article

EphA2 receptor activation by monomeric Ephrin-A1 on supported membranes

scientific article published in December 2011

EphrinB2 clustering by Nipah virus G is required to activate and trap F intermediates at supported lipid bilayer-cell interfaces

scientific article

Fabrication of Multicomponent, Spatially Segregated DNA and Protein-Functionalized Supported Membrane Microarray

scientific article published on 09 August 2018

Flexible linkers in CaMKII control the balance between activating and inhibitory autophosphorylation

scientific article published on 09 March 2020

Fluorescence imaging of membrane dynamics

scientific article published on January 2008

Formation and spatio-temporal evolution of periodic structures in lipid bilayers

scientific article published in January 2005

Graphene-Templated Supported Lipid Bilayer Nanochannels.

scientific article published on 30 June 2016

H-Ras forms dimers on membrane surfaces via a protein-protein interface.

scientific article

Hierarchical assembly of model cell surfaces: synthesis of mucin mimetic polymers and their display on supported bilayers

scientific article published on 11 April 2007

How the T cell signaling network processes information to discriminate between self and agonist ligands

scientific article published on 05 October 2020

Hybrid Live Cell-Supported Membrane Interfaces for Signaling Studies

scientific article published on 03 April 2019

Hybrid protein-lipid patterns from aluminum templates

scientific article

Hydrodynamic damping of membrane thermal fluctuations near surfaces imaged by fluorescence interference microscopy

scientific article published on 20 March 2006

Importin-β modulates the permeability of the nuclear pore complex in a Ran-dependent manner

scientific article

Interfacial Forces Dictate the Pathway of Phospholipid Vesicle Adsorption onto Silicon Dioxide Surfaces

scientific article published on 27 December 2017

Interrogating the T cell synapse with patterned surfaces and photoactivated proteins

scientific article published on 20 August 2007

Investigating cell surface galectin-mediated cross-linking on glycoengineered cells

scientific article

Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding

article

K-Ras4B Remains Monomeric on Membranes over a Wide Range of Surface Densities and Lipid Compositions.

scientific article published in January 2018

Kinetic control of histidine-tagged protein surface density on supported lipid bilayers

scientific article published on 28 February 2008

Kinetic pathways of phase ordering in lipid raft model systems

scientific article published in April 2006

Learning the chemical language of cell-surface interactions

scientific article

Like-charge interactions between colloidal particles are asymmetric with respect to sign.

scientific article

Lipid lateral mobility and membrane phase structure modulation by protein binding.

scientific article published in November 2006

Lipid mobility and molecular binding in fluid lipid membranes

scientific article published in March 2005

Live cell plasma membranes do not exhibit a miscibility phase transition over a wide range of temperatures

scientific article published on 18 March 2015

Many-particle tracking with nanometer resolution in three dimensions by reflection interference contrast microscopy

scientific article

Mapping the stochastic sequence of individual ligand-receptor binding events to cellular activation: T cells act on the rare events.

scientific article published on 15 January 2019

Mechanism of SOS PR-domain autoinhibition revealed by single-molecule assays on native protein from lysate.

scientific article

Membrane Mechanics in Living Cells

scientific article published on 01 January 2019

Membrane Reconstitution of Monoamine Oxidase Enzymes on Supported Lipid Bilayers

scientific article published on 31 August 2018

Membrane array technology for drug discovery.

scientific article

Membrane-dependent signal integration by the Ras activator Son of sevenless

scientific article published on 4 May 2008

Membrane-protein binding measured with solution-phase plasmonic nanocube sensors

scientific article

Micropattern formation in supported lipid membranes

scientific article

Micropatterning fluid lipid bilayers on solid supports

scientific article published on 01 January 1997

Modulation of T cell signaling by the actin cytoskeleton.

scientific article published on March 2013

Molecular kinetics. Ras activation by SOS: allosteric regulation by altered fluctuation dynamics

scientific article

Molecular mechanisms in signal transduction at the membrane

scientific article published on 23 May 2010

Molecular organization and signal transduction at intermembrane junctions

scientific article

Molecular orientation of membrane-anchored mucin glycoprotein mimics

scientific article

Molecular topography imaging by intermembrane fluorescence resonance energy transfer

scientific article

Monitoring lipid anchor organization in cell membranes by PIE-FCCS

scientific article published on 14 June 2012

Monitoring the Waiting Time Sequence of Single Ras GTPase Activation Events Using Liposome Functionalized Zero-Mode Waveguides.

scientific article

Myosin IIA modulates T cell receptor transport and CasL phosphorylation during early immunological synapse formation

scientific article

Nanoscale obstacle arrays frustrate transport of EphA2-Ephrin-A1 clusters in cancer cell lines

scientific article

Negative membrane curvature catalyzes nucleation of endosomal sorting complex required for transport (ESCRT)-III assembly

scientific article

Neuronal activation by GPI-linked neuroligin-1 displayed in synthetic lipid bilayer membranes

scientific article

Neuronal synapse interaction reconstituted between live cells and supported lipid bilayers

scientific article

Noncovalent cell surface engineering: incorporation of bioactive synthetic glycopolymers into cellular membranes

scientific article

Nonequilibrium Adhesion Patterns at Lipid Bilayer Junctions

scientific article published in January 2004

Nonequilibrium patterns of cholesterol-rich chemical heterogenieties within single fluid supported phospholipid bilayer membranes.

scientific article

One-way membrane trafficking of SOS in receptor-triggered Ras activation

scientific article

Optical techniques for imaging membrane topography

scientific article

Patterned two-photon photoactivation illuminates spatial reorganization in live cells

scientific article published on 10 March 2011

Phase segregation on different length scales in a model cell membrane system

scientific article published in October 2005

Phosphotyrosine-mediated LAT assembly on membranes drives kinetic bifurcation in recruitment dynamics of the Ras activator SOS.

scientific article

Protein patterns at lipid bilayer junctions

scholarly article

Quantitative fluorescence microscopy using supported lipid bilayer standards

scientific article published on 30 May 2008

Ratiometric imaging of the T-cell actin cytoskeleton reveals the nature of receptor-induced cytoskeletal enrichment

scientific article published on August 2013

Receptor signaling clusters in the immune synapse

scientific article published on 23 February 2012

Restriction of receptor movement alters cellular response: physical force sensing by EphA2.

scientific article

Roles of the cytoskeleton in regulating EphA2 signals

scientific article

Scanning probe lithography on fluid lipid membranes

scientific article published in November 2004

Signaling clusters in the cell membrane

scientific article published on 12 June 2011

Single molecule kinetics of ENTH binding to lipid membranes.

scientific article

Single-cell analysis of EphA clustering phenotypes to probe cancer cell heterogeneity

scientific article published on 06 August 2020

Size-based chromatography of signaling clusters in a living cell membrane

scientific article

Size-dependent, stochastic nature of lipid exchange between nano-vesicles and model membranes

scientific article

Spatial mutation of the T cell immunological synapse

scientific article published on 27 October 2006

Spatial organization and signal transduction at intercellular junctions

scientific article published on 31 March 2010

Spatial organization of EphA2 at the cell-cell interface modulates trans-endocytosis of ephrinA1.

scientific article

Spatially modulated ephrinA1:EphA2 signaling increases local contractility and global focal adhesion dynamics to promote cell motility

scientific article published on 04 June 2018

Spatiomechanical Modulation of EphB4-Ephrin-B2 Signaling in Neural Stem Cell Differentiation

scientific article published on 23 July 2018

Stochastic geometry sensing and polarization in a lipid kinase-phosphatase competitive reaction

scientific article published on 05 July 2019

Structure and dynamics of supported intermembrane junctions

scientific article

Substrate−Membrane Interactions: Mechanisms for Imposing Patterns on a Fluid Bilayer Membrane

Supported membrane formation, characterization, functionalization, and patterning for application in biological science and technology

scientific article

Supported membranes embedded with fixed arrays of gold nanoparticles

scientific article published on 11 October 2011

Supported membranes in structural biology

scientific article

Supported planar bilayers in studies on immune cell adhesion and communication.

scientific article

Surface binding affinity measurements from order transitions of lipid membrane-coated colloidal particles

scientific article published in January 2006

Sustained α-catenin Activation at E-cadherin Junctions in the Absence of Mechanical Force.

scientific article published on September 2016

Switch-like activation of Bruton's tyrosine kinase by membrane-mediated dimerization

scientific article published on 10 May 2019

Synthesis of lipidated green fluorescent protein and its incorporation in supported lipid bilayers.

scientific article published in October 2005

Synthetic analogues of glycosylphosphatidylinositol-anchored proteins and their behavior in supported lipid bilayers

scientific article

T cell receptor microcluster transport through molecular mazes reveals mechanism of translocation

scientific article

T-cell triggering thresholds are modulated by the number of antigen within individual T-cell receptor clusters

scientific article

TCR and Lat are expressed on separate protein islands on T cell membranes and concatenate during activation.

scientific article published on 13 December 2009

The membrane environment can promote or suppress bistability in cell signaling networks

scientific article published on 13 March 2012

The physical chemistry of membrane curvature

scientific article published on 01 November 2009

The synapse assembly model.

scientific article

Two-step membrane binding by the bacterial SRP receptor enable efficient and accurate Co-translational protein targeting

scientific article published on 28 July 2017

Using patterned supported lipid membranes to investigate the role of receptor organization in intercellular signaling

scientific article

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