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List of works by Sarah E Harris

A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure

scientific article

A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure

scientific article published on 10 April 2019

A pilot study of urinary peptides as biomarkers for intelligence in old age

article

APOE/TOMM40 genetic loci, white matter hyperintensities, and cerebral microbleeds

scientific article published on 26 August 2015

Age-associated cognitive decline

scientific article published in January 2009

Alzheimer's disease susceptibility genes APOE and TOMM40, and brain white matter integrity in the Lothian Birth Cohort 1936.

scientific article published on 08 January 2014

Alzheimer's disease susceptibility genes APOE and TOMM40, and hippocampal volumes in the Lothian birth cohort 1936.

scientific article

An epigenetic predictor of death captures multi-modal measures of brain health

scientific article published on 03 December 2019

Apolipoprotein E is not related to memory abilities at 70 years of age.

scientific article published on 23 October 2008

Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism.

scientific article published on 18 December 2017

Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach

scientific article

Association of existing and new candidate genes for anxiety, depression and personality traits in older people

scientific article

Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits

article

Associations of autozygosity with a broad range of human phenotypes

scientific article published on 31 October 2019

Author Correction: Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism

scientific article published on 01 March 2019

Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

scientific article published on 01 June 2019

Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function ⬇️

scientific article published on 01 May 2019

Cognitive ability at age 11 and 70 years, information processing speed, and APOE variation: the Lothian Birth Cohort 1936 study

scientific article published in March 2009

Common variants of large effect in F12, KNG1, and HRG are associated with activated partial thromboplastin time

scientific article

DNA Methylation and Protein Markers of Chronic Inflammation and Their Associations With Brain and Cognitive Aging

scientific article published on 7 December 2021

Directional dominance on stature and cognition in diverse human populations

scientific article published in July 2015

Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

scientific article published on 23 November 2020

Epigenetic scores for the circulating proteome as tools for disease prediction

scientific article published in 2022

Epigenetic signatures of smoking associate with cognitive function, brain structure, and mental and physical health outcomes in the Lothian Birth Cohort 1936

scientific article published on 07 October 2019

Erratum to: Post-mortem brain analyses of the Lothian Birth Cohort 1936: extending lifetime cognitive and brain phenotyping to the level of the synapse.

scientific article published on 9 December 2015

Evidence for large-scale gene-by-smoking interaction effects on pulmonary function.

scientific article

Evolutionary conserved longevity genes and human cognitive abilities in elderly cohorts

scientific article published on 2 November 2011

Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci

scientific article published on 05 May 2020

Genes from a translational analysis support a multifactorial nature of white matter hyperintensities

scientific article

Genetic Associations Between Fibrinogen and Cognitive Performance in Three Scottish Cohorts

article

Genetic Variants Associated With Altered Plasma Levels of C-Reactive Protein are not Associated With Late-Life Cognitive Ability in Four Scottish Samples

article

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scientific article published on 17 September 2018

Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Genetic basis of a cognitive complexity metric

scientific article

Genetic contributions to stability and change in intelligence from childhood to old age.

scientific article

Genetic contributions to trail making test performance in UK Biobank

article published in 2017

Genetic copy number variation and general cognitive ability

scientific article

Genetic predictors of fibrin D-dimer levels in healthy adults

scientific article

Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation

scientific article published in Nature Communications

Genome-wide analysis of gene dosage in 24,092 individuals estimates that 10,000 genes modulate cognitive ability

scientific article published on 07 January 2021

Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets

scientific article published on 6 February 2017

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.

scientific article

Genome-wide association study identifies 74 loci associated with educational attainment

scientific article published on 11 May 2016

Improved precision of epigenetic clock estimates across tissues and its implication for biological ageing

scientific article published on 23 August 2019

Increased ultra-rare variant load in an isolated Scottish population impacts exonic and regulatory regions

scientific article published on 25 November 2019

Interaction of APOE e4 and poor glycemic control predicts white matter hyperintensity growth from 73 to 76

scientific article

KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference

scientific article

Longevity candidate genes and their association with personality traits in the elderly

scientific article

Longitudinal serum S100β and brain aging in the Lothian Birth Cohort 1936

Longitudinal telomere length shortening and cognitive and physical decline in later life: The Lothian Birth Cohorts 1936 and 1921.

scientific article published on 10 February 2016

Meta-analysis of epigenome-wide association studies of cognitive abilities

scientific article published on 8 January 2018

Meta-analysis of exome array data identifies six novel genetic loci for lung function

scientific article published on 12 January 2018

Meta-analysis of exome array data identifies six novel genetic loci for lung function

Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci

scientific article published on 07 January 2019

Modulation of genetic associations with serum urate levels by body-mass-index in humans

scientific article

Molecular Genetic Contributions to Social Deprivation and Household Income in UK Biobank.

scientific article published on 31 October 2016

Molecular genetic contributions to self-rated health.

scientific article published on 17 November 2016

Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions

Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids

article

Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity

scientific article published in Nature Communications

Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease

scientific article (publication date: 17 September 2013)

Neurology-related protein biomarkers are associated with cognitive ability and brain volume in older age

scientific article published on 10 February 2020

New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals

scientific article published in October 2017

New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

scientific article published on 25 February 2019

New genetic signals for lung function highlight pathways and pleiotropy, and chronic obstructive pulmonary disease associations across multiple ancestries

scholarly article published 12 June 2018

Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

scientific article

Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.

scientific article published on 18 June 2018

Personality Polygenes, Positive Affect, and Life Satisfaction

scientific article published on 22 August 2016

Polygenic risk for coronary artery disease is associated with cognitive ability in older adults

scientific article published on 28 January 2016

Polygenic risk for schizophrenia is associated with cognitive change between childhood and old age.

scientific article published on 16 February 2013

Polygenic risk of ischemic stroke is associated with cognitive ability

scientific article

Post-mortem brain analyses of the Lothian Birth Cohort 1936: extending lifetime cognitive and brain phenotyping to the level of the synapse

scientific article

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scholarly article published in Nature Genetics

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

erratum

Rare and low-frequency variants and their association with plasma levels of fibrinogen, FVII, FVIII, and vWF

scientific article

Reversal of endothelial dysfunction reduces white matter vulnerability in cerebral small vessel disease in rats

scientific article published on 01 July 2018

Seventy-five genetic loci influencing the human red blood cell

scientific article published on 5 December 2012

Shared genetic aetiology between cognitive functions and physical and mental health in UK Biobank (N = 112 151) and 24 GWAS consortia

article

Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation

scientific article

Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function ⬇️

scientific article published on 29 May 2018

The role of variation at AβPP, PSEN1, PSEN2, and MAPT in late onset Alzheimer's disease

scientific article

Trajectories of inflammatory biomarkers over the eighth decade and their associations with immune cell profiles and epigenetic ageing

article by Anna J Stevenson et al published 20 December 2018 in Clinical epigenetics

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

scientific article

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

scientific article published on 12 September 2016

Using regulatory variants to detect gene-gene interactions identifies networks of genes linked to cell immortalisation

scientific article published on 17 January 2020

Variants in doublecortin- and calmodulin kinase like 1, a gene up-regulated by BDNF, are associated with memory and general cognitive abilities

scientific article published on 21 October 2009

Variation in the uric acid transporter gene (SLC2A9) and memory performance

scientific article published on 2 March 2010

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