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List of works by Shunji Takahashi

A crotonyl-CoA reductase-carboxylase independent pathway for assembly of unusual alkylmalonyl-CoA polyketide synthase extender units

scientific article published on 21 December 2016

A new enzyme involved in the control of the stereochemistry in the decalin formation during equisetin biosynthesis

scientific article published on 11 March 2015

A point mutation in ftmD blocks the fumitremorgin biosynthetic pathway in Aspergillus fumigatus strain Af293.

scientific article published on 7 May 2013

Alkyldihydropyrones, new polyketides synthesized by a type III polyketide synthase from Streptomyces reveromyceticus. ⬇️

scientific article

An integrated screening system for the selection of exemplary substrates for natural and engineered cytochrome P450s

scientific article published on 02 December 2019

Aturanosides A and B, Glycosylated Anthraquinones with Antiangiogenic Activity from a Soil-Derived Streptomyces Species

scientific article published on 12 September 2018

Biochemical characterization of a novel indole prenyltransferase from Streptomyces sp. SN-593 ⬇️

scientific article

Biosynthesis and Structure-Activity Relationship Studies of Okaramines That Target Insect Glutamate-Gated Chloride Channels

scientific article published on 31 January 2018

Biosynthesis of Quinolidomicin, the Largest Known Macrolide of Terrestrial Origin: Identification and Heterologous Expression of a Biosynthetic Gene Cluster over 200 kb

scientific article published on 13 December 2018

Biosynthesis of natural products from microbes

scientific article published in October 2007

Catenulisporolides, Glycosylated Triene Macrolides from the Chemically Underexploited Actinomycete Catenulispora Species

scientific article published on 31 October 2018

Characterization of Giant Modular PKSs Provides Insight into Genetic Mechanism for Structural Diversification of Aminopolyol Polyketides

scientific article

ChemInform Abstract: Furaquinocins I and J: Novel Polyketide Isoprenoid Hybrid Compounds from Streptomyces Reveromyceticus SN-593.

scientific article published on 10 November 2011

Construction of a microbial natural product library for chemical biology studies ⬇️

scientific article published on March 8, 2012

Control of the Stereochemical Course of [4+2] Cycloaddition during trans-Decalin Formation by Fsa2-Family Enzymes

scientific article published on 04 July 2018

Creation of novel reveromycin derivatives by alcohol-added fermentation.

scientific article published on 12 December 2012

Detection of cytochrome P450 substrates by using a small-molecule droplet array on an NADH-immobilized solid surface

scientific article published on 07 November 2011

Development of a Terpenoid-Production Platform in Streptomyces reveromyceticus SN-593.

scientific article published on 11 October 2017

Eighth Korea-Japan Chemical Biology symposium: chemical biology notes from a small island

scientific article published on 01 June 2016

Eremophilane sesquiterpenes from capsidiol

scientific article published in October 2004

Establishment and characterization of GSA-1, a human cell line highly susceptible to apoptosis after free-fall

scientific article published on December 2002

Functional analyses of cytochrome P450 genes responsible for the early steps of brassicicene C biosynthesis

scientific article published on 08 August 2009

Functional characterization of premnaspirodiene oxygenase, a cytochrome P450 catalyzing regio- and stereo-specific hydroxylations of diverse sesquiterpene substrates

scientific article

Furaquinocins I and J: novel polyketide isoprenoid hybrid compounds from Streptomyces reveromyceticus SN-593 ⬇️

scientific article published on 25 May 2011

Gene disruption and biochemical characterization of verruculogen synthase of Aspergillus fumigatus.

scientific article published on 18 February 2011

Genetic safeguard against mycotoxin cyclopiazonic acid production in Aspergillus oryzae

scientific article published on 23 May 2011

Haenamindole, an unusual diketopiperazine derivative from a marine-derived Penicillium sp. KCB12F005.

scientific article

Heterologous Expression of the Biosynthetic Gene Cluster for Verticilactam and Identification of Analogues

scientific article published on 20 November 2020

Identification of Middle Chain Fatty Acyl-CoA Ligase Responsible for the Biosynthesis of 2-Alkylmalonyl-CoAs for Polyketide Extender Unit. ⬇️

scientific article published on 16 September 2015

Identification of a gene cluster for telomestatin biosynthesis and heterologous expression using a specific promoter in a clean host.

scientific article published on 13 June 2017

Identification of a novel sesquiterpene biosynthetic machinery involved in astellolide biosynthesis

scientific article published on 15 September 2016

Identification of cytochrome P450s required for fumitremorgin biosynthesis in Aspergillus fumigatus.

scientific article published in March 2009

Identification of the kinanthraquinone biosynthetic gene cluster by expression of an atypical response regulator ⬇️

scientific article published on 6 February 2021

Improvement of Transformation Efficiency by Strategic Circumvention of Restriction Barriers in Streptomyces griseus

scientific article published on July 1, 2011

Increased expression of GRP94 protein is associated with decreased sensitivity to X-rays in cervical cancer cell lines

scientific article published on September 2005

Increased levels of UV‐induced protease activity in human UVAP‐1 cells exposed to gravity‐changing stress: involvement of E‐64‐sensitive proteases in suppression of UV mutagenicity ⬇️

scientific article published on 01 January 2003

Induction of uPA release in human peripheral blood lymphocytes by [deamino-Cysl,D-Arg8]-vasopressin (dDAVP).

scientific article

Kinanthraquinone, a new anthraquinone carboxamide isolated from Streptomyces reveromyceticus SN-593-44. ⬇️

scientific article published on 6 February 2018

Kinetic and molecular analysis of 5-epiaristolochene 1,3-dihydroxylase, a cytochrome P450 enzyme catalyzing successive hydroxylations of sesquiterpenes

scientific article

Leupeptin-sensitive proteases involved in cell survival after X-ray irradiation in human RSa cells

scientific article published in August 2005

Metabolic engineering of sesquiterpene metabolism in yeast

scientific article

Molecular cloning and characterization of a broad substrate terpenoid oxidoreductase from Artemisia annua

scientific article

New Cyclic Lipopeptides of the Iturin Class Produced by Saltern-Derived Bacillus sp. KCB14S006. ⬇️

scientific article published on 2 April 2016

Novel squalene-producing thraustochytrids found in mangrove water.

scientific article

Octaminomycins A and B, Cyclic Octadepsipeptides Active against Plasmodium falciparum.

scientific article

Opantimycin A, a new metabolite isolated from Streptomyces sp. RK88-1355 ⬇️

scientific article published on 07 September 2016

Penidioxolanes A and B, 1,3-Dioxolane Containing Azaphilone Derivatives from Marine-derivedPenicilliumsp. KCB12C078 ⬇️

scientific article

Pentaminomycins A and B, Hydroxyarginine-Containing Cyclic Pentapeptides from Streptomyces sp. RK88-1441.

scientific article published on 7 March 2018

Probing sesquiterpene hydroxylase activities in a coupled assay with terpene synthases

scientific article

Protective role of HSP27 against UVC-induced cell death in human cells

scientific article published on August 2004

Pyrrolizilactone, a new pyrrolizidinone metabolite produced by a fungus.

scientific article published on 29 May 2013

RK-1355A and B, novel quinomycin derivatives isolated from a microbial metabolites fraction library based on NPPlot screening

scientific article published on 5 February 2014

RK-144171, a new benadrostin derivative produced by Streptomyces sp. RK88-1441

scientific article published on 08 June 2016

RK-270A-C, new oxindole derivatives isolated from a microbial metabolites fraction library of Streptomyces sp. RK85-270. ⬇️

scientific article

Reveromycin A biosynthesis uses RevG and RevJ for stereospecific spiroacetal formation.

scientific article published on 5 June 2011

Spirotoamides A and B, novel 6,6-spiroacetal polyketides isolated from a microbial metabolite fraction library ⬇️

scientific article published on December 21, 2011

Stachybotrysin, an Osteoclast Differentiation Inhibitor from the Marine-Derived Fungus Stachybotrys sp. KCB13F013.

scientific article

Structure-function analyses of cytochrome P450revI involved in reveromycin A biosynthesis and evaluation of the biological activity of its substrate, reveromycin T.

scientific article published on 25 September 2014

Structures and biological activities of azaphilones produced by Penicillium sp. KCB11A109 from a ginseng field

scientific article published in February 2016

Surrogate splicing for functional analysis of sesquiterpene synthase genes

scientific article

The Conserved <i>Colletotrichum</i> spp. Effector Candidate CEC3 Induces Nuclear Expansion and Cell Death in Plants

scientific article published on 03 September 2021

Unantimycin A, a new neoantimycin analog isolated from a microbial metabolite fraction library ⬇️

scientific article published on 9 December 2015

Verticilactam, a New Macrolactam Isolated from a Microbial Metabolite Fraction Library ⬇️

scientific article published on October 15, 2010

Wakodecalines A and B, new decaline metabolites isolated from a fungus Pyrenochaetopsis sp. RK10-F058.

scientific article

β-carboline biomediators induce reveromycin production in Streptomyces sp. SN-593 ⬇️

scientific article published on 09 April 2019

β-carboline chemical signals induce reveromycin production through a LuxR family regulator in Streptomyces sp. SN-593

scientific article published on 23 June 2020

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