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List of works by John F Hancock

14-3-3 Facilitates Ras-Dependent Raf-1 Activation In Vitro and In Vivo ⬇️

scientific article published on July 1, 1998

Activity of Plasma Membrane-recruited Raf-1 Is Regulated by Ras via the Raf Zinc Finger ⬇️

scientific article published on 01 August 1997

Acylpeptide hydrolase is a novel regulator of KRAS plasma membrane localization and function

scientific article published on 31 July 2019

An oxanthroquinone derivative that disrupts RAS plasma membrane localization inhibits cancer cell growth

scientific article published on 03 July 2018

Andrographolide derivatives inhibit guanine nucleotide exchange and abrogate oncogenic Ras function ⬇️

scientific article published on 04 June 2013

COS Cell Expression

scientific article published on January 1, 1992

Caveolae regulate the nanoscale organization of the plasma membrane to remotely control Ras signaling

scientific article published on 24 February 2014

Clathrin-independent carriers form a high capacity endocytic sorting system at the leading edge of migrating cells

scientific article

Co-regulation of cell polarization and migration by caveolar proteins PTRF/Cavin-1 and caveolin-1

scientific article

Consensus on the RAS dimerization hypothesis: Strong evidence for lipid-mediated clustering but not for G-domain-mediated interactions

scientific article published in 2023

Evolutionary analysis and molecular dissection of caveola biogenesis

scientific article

Fendiline Inhibits K-Ras Plasma Membrane Localization and Blocks K-Ras Signal Transmission ⬇️

scientific article published on November 5, 2012

Inhibitors of K-Ras plasma membrane localization

scientific article published on 08 August 2013

Lipid modifications and function of the ras superfamily of proteins

scientific article published on May 1, 1992

MURC/Cavin-4 and cavin family members form tissue-specific caveolar complexes

scientific article

Nonsteroidal Anti-inflammatory Drugs Alter the Spatiotemporal Organization of Ras Proteins on the Plasma Membrane ⬇️

scientific article published on March 19, 2012

Nucleophosmin and nucleolin regulate K-Ras plasma membrane interactions and MAPK signal transduction

scientific article published on 06 August 2009

Ras Isoforms Vary in Their Ability to Activate Raf-1 and Phosphoinositide 3-Kinase ⬇️

scientific article published on September 11, 1998

Ras trafficking, localization and compartmentalized signalling ⬇️

scientific article published on September 8, 2011

Reassessing the role of phosphocaveolin-1 in cell adhesion and migration.

scientific article published on 7 October 2007

Signal integration by lipid-mediated spatial cross talk between Ras nanoclusters

scientific article

Sphingomyelin metabolism is a regulator of KRAS function.

scientific article published on 20 November 2017

Targeting plasma membrane phosphatidylserine content to inhibit oncogenic KRAS function

scientific article published on 26 August 2019

The Anti-inflammatory Drug Indomethacin Alters Nanoclustering in Synthetic and Cell Plasma Membranes ⬇️

scientific article published on September 7, 2010

Therapeutic levels of the hydroxmethylglutaryl-coenzyme A reductase inhibitor lovastatin activate ras signaling via phospholipase D2.

scientific article

VPS35 binds farnesylated N-Ras in the cytosol to regulate N-Ras trafficking

scientific article published on 08 August 2016

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