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List of works by Hidewaki Nakagawa

12 new susceptibility loci for prostate cancer identified by genome-wide association study in Japanese population

scientific article published on 27 September 2019

A Comprehensive Peptidome Profiling Technology for the Identification of Early Detection Biomarkers for Lung Adenocarcinoma ⬇️

scientific article (publication date: 12 April 2011)

A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing.

scientific article

A comprehensive multicenter comparison of whole genome sequencing pipelines using a uniform tumor-normal sample pair

A functional variant in NKX3.1 associated with prostate cancer susceptibility down-regulates NKX3.1 expression

scientific article

A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer

scientific article published on 14 September 2014

A practical method to detect SNVs and indels from whole genome and exome sequencing data

scientific article

Allele separation facilitates interpretation of potential splicing alterations and genomic rearrangements

scientific article published on 01 August 2002

Antibody-coupled monolithic silica microtips for highthroughput molecular profiling of circulating exosomes

scientific article

Association of a novel long non-coding RNA in 8q24 with prostate cancer susceptibility

scientific article published on 28 September 2010

C12orf48, termed PARP‐1 binding protein, enhances poly(ADP‐ribose) polymerase‐1 (PARP‐1) activity and protects pancreatic cancer cells from DNA damage ⬇️

scientific article published on January 1, 2011

CLCA2 as a p53-inducible senescence mediator

scientific article published in February 2012

Characterization of HBV integration patterns and timing in liver cancer and HBV-infected livers.

scientific article published on 18 May 2018

Circulating Tumor DNA Analysis for Liver Cancers and Its Usefulness as a Liquid Biopsy

scientific article published on 17 June 2015

Clinical significance of the mutational landscape and fragmentation of circulating tumor DNA in renal cell carcinoma

scientific article published on 25 January 2019

Common variants at 11q12, 10q26 and 3p11.2 are associated with prostate cancer susceptibility in Japanese ⬇️

scientific article published on February 26, 2012

Common variants on 14q32 and 13q12 are associated with DLBCL susceptibility

scientific journal article

Comprehensive genome sequencing of the liver cancer genome ⬇️

scientific article published on November 8, 2012

Correction: Characterization of HBV integration patterns and timing in liver cancer and HBV-infected livers

Deglycosylation and label-free quantitative LC-MALDI MS applied to efficient serum biomarker discovery of lung cancer ⬇️

scientific article published on April 8, 2011

Down-regulation of RAB6KIFL/KIF20A, a kinesin involved with membrane trafficking of discs large homologue 5, can attenuate growth of pancreatic cancer cell

scientific article

Duodenal cancer in a patient with Peutz-Jeghers syndrome: molecular analysis

scientific article

EphA4 receptor, overexpressed in pancreatic ductal adenocarcinoma, promotes cancer cell growth

scientific article

Erratum: Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer

scientific article published on 01 May 2016

Evaluating genetic risk for prostate cancer among Japanese and Latinos

scientific article

Exome Analyses of Long QT Syndrome Reveal Candidate Pathogenic Mutations in Calmodulin-Interacting Genes

scientific article published in 2015

Expression of novel molecules, MICAL2-PV (MICAL2 prostate cancer variants), increases with high Gleason score and prostate cancer progression

scientific article published in May 2006

Genome-wide association study identifies a susceptibility locus for HCV-induced hepatocellular carcinoma

scientific article published on 17 April 2011

Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population

scientific journal article

Genome-wide cDNA microarray analysis of gene expression profiles in pancreatic cancers using populations of tumor cells and normal ductal epithelial cells selected for purity by laser microdissection

scientific article

Genomic Characterization of Biliary Tract Cancers Identifies Driver Genes and Predisposing Mutations.

scientific article published on 19 January 2018

Genomic analysis of pancreatic juice DNA assesses malignant risk of intraductal papillary mucinous neoplasm of pancreas

scientific article published on 21 June 2019

Genomic landscape of colitis-associated cancer indicates the impact of chronic inflammation and its stratification by mutations in the Wnt signaling

scientific article published on 12 December 2017

Germline Pathogenic Variants in 7636 Japanese Patients With Prostate Cancer and 12 366 Controls

scientific article published on 01 April 2020

IRX4 at 5p15 suppresses prostate cancer growth through the interaction with vitamin D receptor, conferring prostate cancer susceptibility

scientific article published on 8 February 2012

Identification and characterization of genomic rearrangements of MSH2 and MLH1 in Lynch syndrome (HNPCC) by novel techniques

scientific article

Identification of C2orf18, termed ANT2BP (ANT2-binding protein), as one of the key molecules involved in pancreatic carcinogenesis

scientific article

Identification of STAG1 as a key mediator of a p53-dependent apoptotic pathway

scientific article

Integrated analysis of whole genome and transcriptome sequencing reveals diverse transcriptomic aberrations driven by somatic genomic changes in liver cancers

scientific article

Integration of multiethnic fine-mapping and genomic annotation to prioritize candidate functional SNPs at prostate cancer susceptibility regions

scientific article

Involvement of the tubulin tyrosine ligase-like family member 4 polyglutamylase in PELP1 polyglutamylation and chromatin remodeling in pancreatic cancer cells

scientific article

Large-scale association analysis in Asians identifies new susceptibility loci for prostate cancer

scientific article

Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases

scientific article published on 08 June 2020

Loss-of-function mutations in Zn-finger DNA-binding domain of HNF4A cause aberrant transcriptional regulation in liver cancer.

scientific article published on 25 May 2018

Mismatch repair gene PMS2: disease-causing germline mutations are frequent in patients whose tumors stain negative for PMS2 protein, but paralogous genes obscure mutation detection and interpretation

scientific article

Molecular analysis of hereditary nonpolyposis colorectal cancer in the United States: high mutation detection rate among clinically selected families and characterization of an American founder genomic deletion of the MSH2 gene

scientific article

Molecular features of hormone-refractory prostate cancer cells by genome-wide gene expression profiles

scientific article

Molecular features of the transition from prostatic intraepithelial neoplasia (PIN) to prostate cancer: genome-wide gene-expression profiles of prostate cancers and PINs

scientific article

Mutational signatures associated with tobacco smoking in human cancer

scientific article (publication date: 3 November 2016)

Nonsyndromic cleft lip with or without cleft palate and cancer: Evaluation of a possible common genetic background through the analysis of GWAS data

scientific article

Novel 5 alpha-steroid reductase (SRD5A3, type-3) is overexpressed in hormone-refractory prostate cancer

scientific article

Novel calmodulin mutations associated with congenital arrhythmia susceptibility

scientific article published on 10 June 2014

Novel lipogenic enzyme ELOVL7 is involved in prostate cancer growth through saturated long-chain fatty acid metabolism

scientific article

Novel tumor marker REG4 detected in serum of patients with resectable pancreatic cancer and feasibility for antibody therapy targeting REG4.

scientific article

Oncogenic role of KIAA0101 interacting with proliferating cell nuclear antigen in pancreatic cancer

scientific article published on March 2007

Preapoptotic protease calpain-2 is frequently suppressed in adult T-cell leukemia ⬇️

scientific article published on March 28, 2013

Prostate cancer genomics, biology, and risk assessment through genome‐wide association studies ⬇️

scientific article published on January 29, 2012

Proteomic profiling of HTLV-1 infected T-cells for the identification of potential biomarkers and therapeutic targets for HTLV-1 associated myelopathy/ tropical spastic paraparesis and adult T-cell leukemia

scientific article published on 6 June 2011

Quantitative structural characterization of local N-glycan microheterogeneity in therapeutic antibodies by energy-resolved oxonium ion monitoring

scientific article

Regulation of protein Citrullination through p53/PADI4 network in DNA damage response

scientific article published on 20 October 2009

Reproducibility, performance, and clinical utility of a genetic risk prediction model for prostate cancer in Japanese

scientific article

Screening for the Lynch syndrome (hereditary nonpolyposis colorectal cancer).

scientific article

Systematic analysis of mutation distribution in three dimensional protein structures identifies cancer driver genes

scientific article

The Transcriptional Landscape of p53 Signalling Pathway

scientific article published on 18 May 2017

Whole Genome Sequencing Analysis for Cancer Genomics and Precision Medicine.

scientific article published on 18 January 2018

Whole genome sequencing and mutation rate analysis of trios with paternal dioxin exposure

scientific article published on 16 July 2018

Whole genome sequencing discriminates hepatocellular carcinoma with intrahepatic metastasis from multi-centric tumors

scientific article

Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer.

scientific article published on 11 April 2016

Whole-genome mutational landscape of liver cancers displaying biliary phenotype reveals hepatitis impact and molecular diversity

scientific article published on 30 January 2015

Whole-genome sequencing and comprehensive variant analysis of a Japanese individual using massively parallel sequencing

article

Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators

scientific article

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