List of works - Michael Fenech

A comparison of folic acid and 5-methyltetrahydrofolate for prevention of DNA damage and cell death in human lymphocytes in vitro

scientific article published in January 2003

A method for non-invasive genotyping of APCmin/+ mice using fecal samples

scientific article published on 30 January 2012

A possible link between iron deficiency and gastrointestinal carcinogenesis

scientific article

A quantitative PCR method for measuring absolute telomere length ⬇️

scientific article published on January 31, 2011

A review of genome mutation and Alzheimer's disease

scientific article published on 8 December 2006

A review of methionine dependency and the role of methionine restriction in cancer growth control and life-span extension ⬇️

scientific article published on February 17, 2012

Altered cytological parameters in buccal cells from individuals with mild cognitive impairment and Alzheimer's disease.

scientific article

An increased micronucleus frequency in peripheral blood lymphocytes predicts the risk of cancer in humans

scientific article published on 14 September 2006

Automation of the buccal micronucleus cytome assay using laser scanning cytometry.

scientific article

Automation of the cytokinesis-block micronucleus cytome assay by laser scanning cytometry and its potential application in radiation biodosimetry.

scientific article published on December 2014

Biomarkers of Alzheimer's disease risk in peripheral tissues; focus on buccal cells.

scientific article

Biomarkers of Nutrition for Development-Folate Review

scientific article

Biomarkers of genetic damage for cancer epidemiology

scientific article

Buccal micronucleus cytome assay: results of an intra- and inter-laboratory scoring comparison

scientific article published on 20 March 2015

Chromosomal biomarkers of genomic instability relevant to cancer

scientific article

Chronic alcohol exposure induces genome damage measured using the cytokinesis-block micronucleus cytome assay and aneuploidy in human B lymphoblastoid cell lines

scientific article

Consensus statement understanding health and malnutrition through a systems approach: the ENOUGH program for early life

scientific article (publication date: 2014)

Consumption of grape seed extract prevents amyloid-beta deposition and attenuates inflammation in brain of an Alzheimer's disease mouse

scientific article

Cortisol is not associated with telomere shortening or chromosomal instability in human lymphocytes cultured under low and high folate conditions

scientific article

Current state of saliva biomarkers for aging and Alzheimer's disease

scientific article published on 01 January 2019

Cytokinesis-block micronucleus assay evolves into a "cytome" assay of chromosomal instability, mitotic dysfunction and cell death

scientific article published on 5 July 2006

Cytokinesis-blocked micronucleus cytome assay biomarkers identify lung cancer cases amongst smokers

scientific article

Effect of smoking habit on the frequency of micronuclei in human lymphocytes: results from the Human MicroNucleus project

scientific article published in March 2003

Erratum to “Intra and inter-laboratory variation in the scoring of micronucici and nucleoplasmic bridges in binucleated human lymphocytes Results of an international slide-scoring exercise by the HUMN project” [Mutat. Res. 534 (2002) 45–64]

scholarly article published in Mutation Research

Estimating the lowest detectable dose of ionizing radiation by the cytokinesis-block micronucleus assay

scientific article

Evaluation of GammaH2AX in Buccal Cells as a Molecular Biomarker of DNA Damage in Alzheimer's Disease in the AIBL Study of Ageing

scientific article published on 06 August 2020

Exposure of insect cells to ionising radiation in vivo induces persistent phosphorylation of a H2AX homologue (H2AvB) ⬇️

scientific article published on June 22, 2013

Folate (vitamin B9) and vitamin B12 and their function in the maintenance of nuclear and mitochondrial genome integrity ⬇️

scientific article published on November 7, 2011

Folate and methionine metabolism in autism: a systematic review

scientific article

Folate deficiency and DNA-methyltransferase inhibition modulate G-quadruplex frequency.

scientific article published on 11 January 2016

G-quadruplexes: A possible epigenetic target for nutrition.

scientific article published on 07 April 2015

Genome health nutrigenomics and nutrigenetics--diagnosis and nutritional treatment of genome damage on an individual basis

scientific article published on 5 July 2007

Genomic stability: a new paradigm for recommended dietary allowances (RDAs).

scientific article

Guanine-quadruplexes are increased in mild cognitive impairment and correlate with cognitive function and chromosomal DNA damage.

scientific article published on 2 August 2016

Health benefits of herbs and spices: the past, the present, the future

scientific article

High Content, Multi-Parameter Analyses in Buccal Cells to Identify Alzheimer's Disease.

scientific article

Human population studies with the exfoliated buccal micronucleus assay: statistical and epidemiological issues

scientific article

Inflammatory cytokine storms severity may be fueled by interactions of micronuclei and RNA viruses such as COVID-19 virus SARS-CoV-2. A hypothesis

scientific article published in 2021

Inter-laboratory consistency and variability in the buccal micronucleus cytome assay depends on biomarker scored and laboratory experience: results from the HUMNxl international inter-laboratory scoring exercise.

scientific article published on 26 September 2016

Intra- and inter-laboratory variation in the scoring of micronuclei and nucleoplasmic bridges in binucleated human lymphocytes. Results of an international slide-scoring exercise by the HUMN project

scientific article published on January 2003

Iron and genome stability: An update ⬇️

scientific article published on February 13, 2012

Laser scanning cytometry for automation of the micronucleus assay

scientific article

Low intake of calcium, folate, nicotinic acid, vitamin E, retinol, beta-carotene and high intake of pantothenic acid, biotin and riboflavin are significantly associated with increased genome instability--results from a dietary intake and micronucleu

scientific article published on 10 February 2005

Low-grade inflammation, diet composition and health: current research evidence and its translation

scientific article (publication date: 14 October 2015)

Mental health literacy, folic acid and vitamin B12, and physical activity for the prevention of depression in older adults: randomised controlled trial

scientific article published in July 2010

Micronuclei, inflammation and auto-immune disease

scientific article published on 15 September 2020

Micronucleus assay with urine derived cells (UDC): a review of its application in human studies investigating genotoxin exposure and bladder cancer risk

scientific article published on 09 May 2014

Molecular mechanisms by which in vivo exposure to exogenous chemical genotoxic agents can lead to micronucleus formation in lymphocytes in vivo and ex vivo in humans

scientific article

No clear potentiation of antidepressant medication effects by folic acid+vitamin B12 in a large community sample

scientific article

Nutrigenetics and nutrigenomics: viewpoints on the current status and applications in nutrition research and practice

scientific article

Nutrition and genome health

scientific article published on January 2007

Occupational Exposure to Pesticides in Tobacco Fields: The Integrated Evaluation of Nutritional Intake and Susceptibility on Genomic and Epigenetic Instability.

scientific article

Smoking causes induction of micronuclei and other nuclear anomalies in cervical cells

scientific article published on 20 February 2020

Sunlight and vitamin D affect DNA damage, cell division and cell death in human lymphocytes: a cross-sectional study in South Australia

scientific article

The Genome Health Clinic and Genome Health Nutrigenomics concepts: diagnosis and nutritional treatment of genome and epigenome damage on an individual basis

scientific article

The HUMN and HUMNxL international collaboration projects on human micronucleus assays in lymphocytes and buccal cells--past, present and future

scientific article

The HUMNxl scoring criteria for different cell types and nuclear anomalies in the buccal micronucleus cytome assay - an update and expanded photogallery

scientific article published on 11 August 2013

The HUman MicroNucleus project on eXfoLiated buccal cells (HUMN(XL)): the role of life-style, host factors, occupational exposures, health status, and assay protocol.

scientific article published on 08 July 2011

The Micronutrient Genomics Project: a community-driven knowledge base for micronutrient research

scientific article

The Role of Genetic Polymorphisms as Related to One-Carbon Metabolism, Vitamin B6, and Gene-Nutrient Interactions in Maintaining Genomic Stability and Cell Viability in Chinese Breast Cancer Patients.

scientific article

The case for strategic international alliances to harness nutritional genomics for public and personal health

scientific article published in November 2005

The potential role of the antioxidant and detoxification properties of glutathione in autism spectrum disorders: a systematic review and meta-analysis ⬇️

scientific article published on April 24, 2012

Use of the lymphocyte cytokinesis-block micronucleus assay in occupational biomonitoring of genome damage caused by in vivo exposure to chemical genotoxins: Past, present and future

scientific article

Zinc deficiency or excess within the physiological range increases genome instability and cytotoxicity, respectively, in human oral keratinocyte cells ⬇️

scientific article published on September 21, 2011

n-3 Fatty Acid Supplementation and Leukocyte Telomere Length in Patients with Chronic Kidney Disease

scientific article published on 19 March 2016

γH2AX is increased in peripheral blood lymphocytes of Alzheimer's disease patients in the South Australian Neurodegeneration, Nutrition and DNA Damage (SAND) study of aging

article

γH2AX responses in human buccal cells exposed to ionizing radiation

scientific article published on 16 December 2014

List of works by Michael Fenech

A comparison of folic acid and 5-methyltetrahydrofolate for prevention of DNA damage and cell death in human lymphocytes in vitro

A method for non-invasive genotyping of APCmin/+ mice using fecal samples

A possible link between iron deficiency and gastrointestinal carcinogenesis

A quantitative PCR method for measuring absolute telomere length ⬇️

A review of genome mutation and Alzheimer's disease

A review of methionine dependency and the role of methionine restriction in cancer growth control and life-span extension ⬇️

Altered cytological parameters in buccal cells from individuals with mild cognitive impairment and Alzheimer's disease.

An increased micronucleus frequency in peripheral blood lymphocytes predicts the risk of cancer in humans

Automation of the buccal micronucleus cytome assay using laser scanning cytometry.

Automation of the cytokinesis-block micronucleus cytome assay by laser scanning cytometry and its potential application in radiation biodosimetry.

Biomarkers of Alzheimer's disease risk in peripheral tissues; focus on buccal cells.

Biomarkers of Nutrition for Development-Folate Review

Biomarkers of genetic damage for cancer epidemiology

Buccal micronucleus cytome assay: results of an intra- and inter-laboratory scoring comparison

Chromosomal biomarkers of genomic instability relevant to cancer

Chronic alcohol exposure induces genome damage measured using the cytokinesis-block micronucleus cytome assay and aneuploidy in human B lymphoblastoid cell lines

Consensus statement understanding health and malnutrition through a systems approach: the ENOUGH program for early life

Consumption of grape seed extract prevents amyloid-beta deposition and attenuates inflammation in brain of an Alzheimer's disease mouse

Cortisol is not associated with telomere shortening or chromosomal instability in human lymphocytes cultured under low and high folate conditions

Current state of saliva biomarkers for aging and Alzheimer's disease

Cytokinesis-block micronucleus assay evolves into a "cytome" assay of chromosomal instability, mitotic dysfunction and cell death

Cytokinesis-blocked micronucleus cytome assay biomarkers identify lung cancer cases amongst smokers

Effect of smoking habit on the frequency of micronuclei in human lymphocytes: results from the Human MicroNucleus project

Erratum to “Intra and inter-laboratory variation in the scoring of micronucici and nucleoplasmic bridges in binucleated human lymphocytes Results of an international slide-scoring exercise by the HUMN project” [Mutat. Res. 534 (2002) 45–64]

Estimating the lowest detectable dose of ionizing radiation by the cytokinesis-block micronucleus assay

Evaluation of GammaH2AX in Buccal Cells as a Molecular Biomarker of DNA Damage in Alzheimer's Disease in the AIBL Study of Ageing

Exposure of insect cells to ionising radiation in vivo induces persistent phosphorylation of a H2AX homologue (H2AvB) ⬇️

Folate (vitamin B9) and vitamin B12 and their function in the maintenance of nuclear and mitochondrial genome integrity ⬇️

Folate and methionine metabolism in autism: a systematic review

Folate deficiency and DNA-methyltransferase inhibition modulate G-quadruplex frequency.

G-quadruplexes: A possible epigenetic target for nutrition.

Genome health nutrigenomics and nutrigenetics--diagnosis and nutritional treatment of genome damage on an individual basis

Genomic stability: a new paradigm for recommended dietary allowances (RDAs).

Guanine-quadruplexes are increased in mild cognitive impairment and correlate with cognitive function and chromosomal DNA damage.

Health benefits of herbs and spices: the past, the present, the future

High Content, Multi-Parameter Analyses in Buccal Cells to Identify Alzheimer's Disease.

Human population studies with the exfoliated buccal micronucleus assay: statistical and epidemiological issues

Inflammatory cytokine storms severity may be fueled by interactions of micronuclei and RNA viruses such as COVID-19 virus SARS-CoV-2. A hypothesis

Inter-laboratory consistency and variability in the buccal micronucleus cytome assay depends on biomarker scored and laboratory experience: results from the HUMNxl international inter-laboratory scoring exercise.

Intra- and inter-laboratory variation in the scoring of micronuclei and nucleoplasmic bridges in binucleated human lymphocytes. Results of an international slide-scoring exercise by the HUMN project

Iron and genome stability: An update ⬇️

Laser scanning cytometry for automation of the micronucleus assay

Low intake of calcium, folate, nicotinic acid, vitamin E, retinol, beta-carotene and high intake of pantothenic acid, biotin and riboflavin are significantly associated with increased genome instability--results from a dietary intake and micronucleu

Low-grade inflammation, diet composition and health: current research evidence and its translation

Mental health literacy, folic acid and vitamin B12, and physical activity for the prevention of depression in older adults: randomised controlled trial

Micronuclei, inflammation and auto-immune disease

Micronucleus assay with urine derived cells (UDC): a review of its application in human studies investigating genotoxin exposure and bladder cancer risk

Molecular mechanisms by which in vivo exposure to exogenous chemical genotoxic agents can lead to micronucleus formation in lymphocytes in vivo and ex vivo in humans

No clear potentiation of antidepressant medication effects by folic acid+vitamin B12 in a large community sample

Nutrigenetics and nutrigenomics: viewpoints on the current status and applications in nutrition research and practice

Nutrition and genome health

Occupational Exposure to Pesticides in Tobacco Fields: The Integrated Evaluation of Nutritional Intake and Susceptibility on Genomic and Epigenetic Instability.

Smoking causes induction of micronuclei and other nuclear anomalies in cervical cells

Sunlight and vitamin D affect DNA damage, cell division and cell death in human lymphocytes: a cross-sectional study in South Australia

The Genome Health Clinic and Genome Health Nutrigenomics concepts: diagnosis and nutritional treatment of genome and epigenome damage on an individual basis

The HUMN and HUMNxL international collaboration projects on human micronucleus assays in lymphocytes and buccal cells--past, present and future

The HUMNxl scoring criteria for different cell types and nuclear anomalies in the buccal micronucleus cytome assay - an update and expanded photogallery

The HUman MicroNucleus project on eXfoLiated buccal cells (HUMN(XL)): the role of life-style, host factors, occupational exposures, health status, and assay protocol.

The Micronutrient Genomics Project: a community-driven knowledge base for micronutrient research

The Role of Genetic Polymorphisms as Related to One-Carbon Metabolism, Vitamin B6, and Gene-Nutrient Interactions in Maintaining Genomic Stability and Cell Viability in Chinese Breast Cancer Patients.

The case for strategic international alliances to harness nutritional genomics for public and personal health

The potential role of the antioxidant and detoxification properties of glutathione in autism spectrum disorders: a systematic review and meta-analysis ⬇️

Use of the lymphocyte cytokinesis-block micronucleus assay in occupational biomonitoring of genome damage caused by in vivo exposure to chemical genotoxins: Past, present and future

Zinc deficiency or excess within the physiological range increases genome instability and cytotoxicity, respectively, in human oral keratinocyte cells ⬇️

n-3 Fatty Acid Supplementation and Leukocyte Telomere Length in Patients with Chronic Kidney Disease

γH2AX is increased in peripheral blood lymphocytes of Alzheimer's disease patients in the South Australian Neurodegeneration, Nutrition and DNA Damage (SAND) study of aging

γH2AX responses in human buccal cells exposed to ionizing radiation