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List of works by Atsushi Manabe

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NUDT15 polymorphisms alter thiopurine metabolism and hematopoietic toxicity

scientific journal article
Expansion of human NOD/SCID-repopulating cells by stem cell factor, Flk2/Flt3 ligand, thrombopoietin, IL-6, and soluble IL-6 receptor

scientific article published on April 2000
Diagnosis and classification of myelodysplastic syndrome: International Working Group on Morphology of myelodysplastic syndrome (IWGM-MDS) consensus proposals for the definition and enumeration of myeloblasts and ring sideroblasts

scientific article
Clinical outcome of children with newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia treated between 1995 and 2005.

scientific article
Generation of definitive hematopoietic stem cells from murine early yolk sac and paraaortic splanchnopleures by aorta-gonad-mesonephros region-derived stromal cells

scientific article published in July 2001
Bone marrow-derived stromal cells prevent apoptotic cell death in B-lineage acute lymphoblastic leukemia

scientific article published in May 1992
Acute lymphoblastic leukemia in children with Down syndrome: a retrospective analysis from the Ponte di Legno study group

scientific article
Mutations of an E3 ubiquitin ligase c-Cbl but not TET2 mutations are pathogenic in juvenile myelomonocytic leukemia

scientific article
Susceptibility to 6-MP toxicity conferred by a NUDT15 variant in Japanese children with acute lymphoblastic leukaemia

scientific article
No advantage of dexamethasone over prednisolone for the outcome of standard- and intermediate-risk childhood acute lymphoblastic leukemia in the Tokyo Children's Cancer Study Group L95-14 protocol

scientific article published in September 2005
CD34 expression on long-term repopulating hematopoietic stem cells changes during developmental stages

scientific article published in January 2001
Spontaneous improvement of hematologic abnormalities in patients having juvenile myelomonocytic leukemia with specific RAS mutations

scientific article published on 01 March 2007
Significance of the complete clearance of peripheral blasts after 7 days of prednisolone treatment in children with acute lymphoblastic leukemia: the Tokyo Children's Cancer Study Group Study L99-15.

scientific article published on 2 June 2008
Clinical significance of early T‐cell precursor acute lymphoblastic leukaemia: results of the Tokyo Children’s Cancer Study Group Study L99‐15

scientific article published on November 30, 2011
Evidence for the presence of murine primitive megakaryocytopoiesis in the early yolk sac.

scientific article
Allogeneic hematopoietic stem cell transplantation for 27 children with juvenile myelomonocytic leukemia diagnosed based on the criteria of the International JMML Working Group

scientific article published in April 2002
Long-term results of Tokyo Children's Cancer Study Group trials for childhood acute lymphoblastic leukemia, 1984-1999.

scientific article published on 24 December 2009
Six months of maintenance chemotherapy after intensified treatment for acute lymphoblastic leukemia of childhood

scientific article published on 01 April 2000
Correlation of clinical features with the mutational status of GM-CSF signaling pathway-related genes in juvenile myelomonocytic leukemia

scientific article
Natural killer cell depletion by anti-asialo GM1 antiserum treatment enhances human hematopoietic stem cell engraftment in NOD/Shi-scid mice

scientific article published on 01 December 2000
Characterization of pediatric Philadelphia-negative B-cell precursor acute lymphoblastic leukemia with kinase fusions in Japan

scientific article published on 13 May 2016
ZNF384-related fusion genes define a subgroup of childhood B-cell precursor acute lymphoblastic leukemia with a characteristic immunotype

scientific article published on 15 September 2016
Stimulation of mouse and human primitive hematopoiesis by murine embryonic aorta-gonad-mesonephros-derived stromal cell lines

scientific article published on September 15, 1998
Adhesion-dependent survival of normal and leukemic human B lymphoblasts on bone marrow stromal cells

scientific article published on 01 February 1994
CBL mutation in chronic myelomonocytic leukemia secondary to familial platelet disorder with propensity to develop acute myeloid leukemia (FPD/AML).

scientific article
Prolonged survival of B-lineage acute lymphoblastic leukemia cells is accompanied by overexpression of bcl-2 protein.

scientific article
A novel recurrent EP300-ZNF384 gene fusion in B-cell precursor acute lymphoblastic leukemia.

scientific article published on 6 May 2015
Incidence and survival rates of hematological malignancies in Japanese children and adolescents (2006–2010): based on registry data from the Japanese Society of Pediatric Hematology

scientific article published on May 24, 2013
Myelodysplastic syndrome in childhood: a retrospective study of 189 patients in Japan

scientific article published on 01 November 2001
Spectrum of molecular defects in juvenile myelomonocytic leukaemia includes ASXL1 mutations

scientific article published on 12 April 2010
Treatment and biology of pediatric acute lymphoblastic leukemia

scientific article published on 16 November 2017
Recurrent SPI1 (PU.1) fusions in high-risk pediatric T cell acute lymphoblastic leukemia.

scientific article
AML1/RUNX1 mutations are infrequent, but related to AML-M0, acquired trisomy 21, and leukemic transformation in pediatric hematologic malignancies

scientific article
Clinical utility of next-generation sequencing for inherited bone marrow failure syndromes.

scientific article published on 19 January 2017
Hyperdiploid acute lymphoblastic leukemia with 51 to 65 chromosomes: a distinct biological entity with a marked propensity to undergo apoptosis

scientific article published on 01 January 1999
Interleukin-4 induces programmed cell death (apoptosis) in cases of high-risk acute lymphoblastic leukemia

scientific article published on April 1994
A conditioning regimen of busulfan, fludarabine, and melphalan for allogeneic stem cell transplantation in children with juvenile myelomonocytic leukemia

scientific article published on 6 April 2008
Wiskott-Aldrich syndrome presenting with a clinical picture mimicking juvenile myelomonocytic leukaemia

scientific article
Long-term follow-up of childhood acute lymphoblastic leukemia in Tokyo Children's Cancer Study Group 1981-1995

scientific article published on 01 December 2000
Validation of the Japanese version of the Pediatric Quality of Life Inventory (PedsQL) Cancer Module

scientific article published on April 10, 2011
Flash survey on severe acute respiratory syndrome coronavirus-2 infections in paediatric patients on anticancer treatment

scientific article published on 07 April 2020
The effects of inherited NUDT15 polymorphisms on thiopurine active metabolites in Japanese children with acute lymphoblastic leukemia

scientific article published on 25 April 2017
Aggressive Transformation of Juvenile Myelomonocytic Leukemia Associated with Duplication of Oncogenic KRAS due to Acquired Uniparental Disomy

Preclinical evaluation of NUDT15-guided thiopurine therapy and its effects on toxicity and anti-leukemic efficacy.

scientific article published on 23 March 2018
Multidrug resistance protein 4 (MRP4) polymorphisms impact the 6-mercaptopurine dose tolerance during maintenance therapy in Japanese childhood acute lymphoblastic leukemia

scientific article published on November 18, 2014
Prevalence and growth characteristics of malignant stem cells in B-lineage acute lymphoblastic leukemia

scientific article published on 01 May 1997
Clinical and genetic characteristics of congenital sideroblastic anemia: comparison with myelodysplastic syndrome with ring sideroblast (MDS-RS)

scientific article published on September 16, 2012
Current evidence for an inherited genetic basis of childhood acute lymphoblastic leukemia

scientific article published on December 13, 2012
Methylation status of the p15 and p16 genes in paediatric myelodysplastic syndrome and juvenile myelomonocytic leukaemia

scientific article
The activity of the inosine triphosphate pyrophosphatase affects toxicity of 6-mercaptopurine during maintenance therapy for acute lymphoblastic leukemia in Japanese children

scientific article published on December 24, 2011

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