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List of works by Patrick Hwu

18F-fluorodeoxyglucose positron emission tomography correlates with tumor immunometabolic phenotypes in resected lung cancer

scientific article published on 16 April 2020

2E8 binds to the high affinity I-domain in a metal ion-dependent manner: a second generation monoclonal antibody selectively targeting activated LFA-1.

scientific article published on 19 August 2010

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): late breaking abstracts: National Harbor, MD, USA. 9-13 November 2016.

scientific article published on 8 December 2016

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

scientific article (publication date: November 2016)

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two: National Harbor, MD, USA. 9-13 November 2016

scientific article published oln 16 November 2016

4-1BB Agonist Focuses CD8+ Tumor-Infiltrating T-Cell Growth into a Distinct Repertoire Capable of Tumor Recognition in Pancreatic Cancer.

scientific article

A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade

article

A Critical Assessment of Adjuvant Radiotherapy for Inguinal Lymph Node Metastases from Melanoma

scientific article published on 01 December 2004

A First-in-Human Study and Biomarker Analysis of NKTR-214, a Novel IL2Rβγ-Biased Cytokine, in Patients with Advanced or Metastatic Solid Tumors

scientific article published on 15 April 2019

A Novel Method to Generate and Expand Clinical-Grade, Genetically Modified, Tumor-Infiltrating Lymphocytes

scientific article published on 2 August 2017

A Phase 1b Study Evaluating the Safety, Tolerability, and Immunogenicity of CMB305, a Lentiviral-Based Prime-Boost Vaccine Regimen, in Patients with Locally Advanced, Relapsed, or Metastatic Cancer Expressing NY-ESO-1

scientific article published on 19 November 2020

A case report of Grover's disease from immunotherapy-a skin toxicity induced by inhibition of CTLA-4 but not PD-1.

scientific article published on 20 September 2016

A new approach to simultaneously quantify both TCR α- and β-chain diversity after adoptive immunotherapy

scientific article published on 03 July 2012

A novel strategy for rapid and efficient isolation of human tumor-specific CD4(+) and CD8(+) T-cell clones

scientific article

A peptidoglycan monomer with the glutamine to serine change and basic peptides bind in silico to TLR-2 (403–455) ⬇️

scientific article published on December 28, 2010

A phase I study of TPI 287 in combination with temozolomide for patients with metastatic melanoma

scientific article published on 18 August 2016

A phase I study of nonmyeloablative chemotherapy and adoptive transfer of autologous tumor antigen-specific T lymphocytes in patients with metastatic melanoma

scientific article

A phase I study on adoptive immunotherapy using gene-modified T cells for ovarian cancer

scientific article

A phase IB trial of intravenous INO-1001 plus oral temozolomide in subjects with unresectable stage-III or IV melanoma.

scientific article published in August 2009

A phase II study of gefitinib in patients with metastatic melanoma ⬇️

scientific article published on August 1, 2011

A phase II study of ipilimumab plus temozolomide in patients with metastatic melanoma

scientific article published on 13 June 2017

A randomized phase II study of cilengitide (EMD 121974) in patients with metastatic melanoma.

scientific article published on August 2012

A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer

scientific article published on July 2003

A-to-I RNA Editing Contributes to Proteomic Diversity in Cancer

scientific article published on 26 April 2018

AACR Cancer Progress Report 2016

scientific article published on 01 October 2016

Activation and propagation of tumor-infiltrating lymphocytes on clinical-grade designer artificial antigen-presenting cells for adoptive immunotherapy of melanoma

scientific article

Activity of dasatinib against L576P KIT mutant melanoma: molecular, cellular, and clinical correlates

scientific article

Adjuvant Ipilimumab in High-Risk Uveal Melanoma

scientific article published on 29 January 2019

Adoptive T-cell therapy using autologous tumor-infiltrating lymphocytes for metastatic melanoma: current status and future outlook

scientific article

Advances in the development of cancer immunotherapies ⬇️

scientific article published on September 30, 2012

Advances in the treatment of metastatic melanoma: adoptive T-cell therapy

scientific article

Altered decamer and nonamer from an HLA-A0201-restricted epitope of Survivin differentially stimulate T-cell responses in different individuals ⬇️

scientific article published on February 12, 2011

Analysis of Immune Signatures in Longitudinal Tumor Samples Yields Insight into Biomarkers of Response and Mechanisms of Resistance to Immune Checkpoint Blockade

scientific article published on 14 June 2016

Analysis of the intratumoral adaptive immune response in well differentiated and dedifferentiated retroperitoneal liposarcoma

scientific article published on 29 January 2015

Antagonist antibodies to PD-1 and B7-H1 (PD-L1) in the treatment of advanced human cancer--letter

scientific article

Anti-OX40 Antibody Directly Enhances The Function of Tumor-Reactive CD8+ T Cells and Synergizes with PI3Kβ Inhibition in PTEN Loss Melanoma

scientific article published on 01 August 2019

Antitumor T-cell responses contribute to the effects of dasatinib on c-KIT mutant murine mastocytoma and are potentiated by anti-OX40 ⬇️

scientific article published on August 30, 2012

Assessment of Image-Guided Intratumoral Delivery of Immunotherapeutics in Patients With Cancer

scientific article published on 01 July 2020

Association between melanoma and renal-cell carcinoma for sequential diagnoses: A single-center retrospective study

scientific article published on 19 October 2018

Association of body-mass index and outcomes in patients with metastatic melanoma treated with targeted therapy, immunotherapy, or chemotherapy: a retrospective, multicohort analysis.

scientific article published on 12 February 2018

Atezolizumab plus cobimetinib and vemurafenib in BRAF-mutated melanoma patients

scientific article published on 06 June 2019

Aurora kinase inhibition sensitizes melanoma cells to T-cell-mediated cytotoxicity

scientific article published on 29 October 2020

Author Correction: Bone morphogenetic protein 7 promotes resistance to immunotherapy

scientific article published on 08 October 2020

Author Correction: Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma

scientific article published on 01 December 2018

B cells and tertiary lymphoid structures promote immunotherapy response

scientific article published on 15 January 2020

BRAF Inhibition Increases Tumor Infiltration by T cells and Enhances the Antitumor Activity of Adoptive Immunotherapy in Mice ⬇️

scientific article published on November 30, 2012

BRAF inhibition is associated with enhanced melanoma antigen expression and a more favorable tumor microenvironment in patients with metastatic melanoma.

scientific article published on 10 January 2013

BRAF, NRAS and KIT sequencing analysis of spindle cell melanoma

scientific article published on 19 July 2012

BRAFV600E Co-opts a Conserved MHC Class I Internalization Pathway to Diminish Antigen Presentation and CD8+ T-cell Recognition of Melanoma

scientific article published on 20 March 2015

BTLA marks a less-differentiated tumor-infiltrating lymphocyte subset in melanoma with enhanced survival properties

scientific article

Bempegaldesleukin (NKTR-214) plus Nivolumab in Patients with Advanced Solid Tumors: Phase I Dose-Escalation Study of Safety, Efficacy, and Immune Activation (PIVOT-02)

scientific article published on 21 May 2020

Bempegaldesleukin selectively depletes intratumoral Tregs and potentiates T cell-mediated cancer therapy

scientific article published on 31 January 2020

Beyond BRAF(V600): clinical mutation panel testing by next-generation sequencing in advanced melanoma

scientific article

Biochemotherapy in patients with advanced head and neck mucosal melanoma

scientific article

Blockade of the PD-1 pathway enhances the efficacy of adoptive cell therapy against cancer ⬇️

scientific article published on February 1, 2013

Bone morphogenetic protein 7 promotes resistance to immunotherapy

scientific article published on 24 September 2020

Broad cross-presentation of the hematopoietically derived PR1 antigen on solid tumors leads to susceptibility to PR1-targeted immunotherapy.

scientific article

Bypassing STAT3-mediated inhibition of the transcriptional regulator ID2 improves the antitumor efficacy of dendritic cells

scientific article published on 27 September 2016

CD40 ligand and lipopolysaccharide enhance the in vitro generation of melanoma-reactive T-cells ⬇️

scientific article published on 01 January 2002

Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes

scientific article

Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma

scientific article

Cell transfer therapy for cancer: lessons from sequential treatments of a patient with metastatic melanoma

scientific article published on September 2003

Cervical Cancer Neoantigen Landscape and Immune Activity is Associated with Human Papillomavirus Master Regulators

scientific article

Challenges of chemosensitivity testing

scientific article published on 01 September 2006

Characterizing the clinical benefit of ipilimumab in patients who progressed on high-dose IL-2

Chemical Castration of Melanoma Patients Does Not Increase the Frequency of Tumor-specific CD4 and CD8 T Cells After Peptide Vaccination ⬇️

scientific article published on May 1, 2013

Chimeric antigen receptor T-cell therapy - assessment and management of toxicities.

scientific article

Circulating Tumor Cells and Early Relapse in Node-positive Melanoma

scientific article published on 03 February 2020

Clinical characteristics and outcomes with specific BRAF and NRAS mutations in patients with metastatic melanoma

scientific article published on 6 August 2013

Clinical, Molecular, and Immune Analysis of Dabrafenib-Trametinib Combination Treatment for BRAF Inhibitor-Refractory Metastatic Melanoma: A Phase 2 Clinical Trial

scientific article published on 28 April 2016

Clinicopathological features and clinical outcomes associated with TP53 and BRAFNon-V600 mutations in cutaneous melanoma patients

scientific article published on 2 December 2016

Co-Stimulation through 4-1BB/CD137 Improves the Expansion and Function of CD8+ Melanoma Tumor-Infiltrating Lymphocytes for Adoptive T-Cell Therapy ⬇️

scientific article published on January 1, 2013

Combined-modality therapy for patients with regional nodal metastases from melanoma

scientific article published on 22 September 2005

Comparison of two dosing schedules of palonosetron for the prevention of nausea and vomiting due to interleukin-2-based biochemotherapy ⬇️

scientific article published on January 25, 2012

Complementing T-cell Function: An Inhibitory Role of the Complement System in T-cell-Mediated Antitumor Immunity

scientific article

Complete loss of PTEN protein expression correlates with shorter time to brain metastasis and survival in stage IIIB/C melanoma patients with BRAFV600 mutations

scientific article

Complete response of stage IV anal mucosal melanoma expressing KIT Val560Asp to the multikinase inhibitor sorafenib

scientific article

Comprehensive T cell repertoire characterization of non-small cell lung cancer

scientific article published on 30 January 2020

Correction to: Infliximab associated with faster symptom resolution compared with corticosteroids alone for the management of immune-related enterocolitis

scholarly article by Daniel H Johnson et al published 17 April 2019 in Journal for Immunotherapy of Cancer

Correlation of BRAF Mutation Status in Circulating-Free DNA and Tumor and Association with Clinical Outcome across Four BRAFi and MEKi Clinical Trials.

scientific article published on 7 October 2015

Correlation of NRAS Mutations With Clinical Response to High-dose IL-2 in Patients With Advanced Melanoma ⬇️

scientific article published on January 1, 2012

Costimulation Through the CD137/4-1BB Pathway Protects Human Melanoma Tumor-infiltrating Lymphocytes From Activation-induced Cell Death and Enhances Antitumor Effector Function ⬇️

scientific article published on April 1, 2011

Cumulative Incidence and Predictors of CNS Metastasis for Patients With American Joint Committee on Cancer 8th Edition Stage III Melanoma

scientific article published on 28 January 2020

Cutaneous squamous cell carcinoma and inflammation of actinic keratoses associated with sorafenib

scientific article published on January 2009

De-Risking Immunotherapy: Report of a Consensus Workshop of the Cancer Immunotherapy Consortium of the Cancer Research Institute.

scientific article published on April 2016

Defective STAT1 activation associated with impaired IFN-γ production in NK and T lymphocytes from metastatic melanoma patients treated with IL-2.

scientific article published on 11 April 2016

Defining the critical hurdles in cancer immunotherapy

scientific article published on 14 December 2011

Dendritic cells strongly boost the antitumor activity of adoptively transferred T cells in vivo.

scientific article

Detection and Characterization of a Novel Subset of CD8+CD57+ T Cells in Metastatic Melanoma with an Incompletely Differentiated Phenotype ⬇️

scientific article published on February 3, 2012

Development of novel combinations of targeted and immunotherapies by understanding immune resistance using a high throughput assay of T cell mediated cytotoxicity

scientific article published on 7 November 2013

Differential expression of the G-protein-coupled formyl Peptide receptor in melanoma associates with aggressive phenotype.

scientific article published in April 2013

Distinct clinical patterns and immune infiltrates are observed at time of progression on targeted therapy versus immune checkpoint blockade for melanoma

scientific article published on 2 February 2016

Does complete response to systemic therapy in patients with stage IV melanoma translate into long-term survival?

scientific article published on February 1, 2011

Dual-specific T cells combine proliferation and antitumor activity

scientific article published on 4 November 2002

Effective innate and adaptive antimelanoma immunity through localized TLR7/8 activation

scientific article

Epithelial-Mesenchymal Transition Is Associated with a Distinct Tumor Microenvironment Including Elevation of Inflammatory Signals and Multiple Immune Checkpoints in Lung Adenocarcinoma

scientific article published on 5 February 2016

Erratum to: A case report of Grover's disease from immunotherapy-a skin toxicity induced by inhibition of CTLA-4 but not PD-1.

scientific article published on 18 January 2017

Exploiting the neoantigen landscape for immunotherapy of pancreatic ductal adenocarcinoma

scientific article published on 20 October 2016

Expression of a "self-"antigen by human tumor cells enhances tumor antigen-specific CD4(+) T-cell function.

scientific article

First-in-Class, First-in-Human Study Evaluating LV305, a Dendritic-Cell Tropic Lentiviral Vector, in Sarcoma and Other Solid Tumors Expressing NY-ESO-1

scientific article published on 21 June 2019

Forging a link between oncogenic signaling and immunosuppression in melanoma ⬇️

scientific article published on February 1, 2013

GNA11 Mutation in a Patient With Cutaneous Origin Melanoma: A Case Report

scientific article published on January 2016

GPNMB expression in uveal melanoma: a potential for targeted therapy.

scientific article published on June 2010

Genetically modified artificial antigen-presenting cells (aAPC) for expansion of melanoma tumor infiltrating lymphocytes with optimal properties for adoptive cell therapy

scientific article published on 7 November 2013

Genomic and immune heterogeneity are associated with differential responses to therapy in melanoma.

scientific article

Genomic profiling of dedifferentiated liposarcoma compared to matched well-differentiated liposarcoma reveals higher genomic complexity and a common origin.

scientific article published on 2 April 2018

Gut microbiome modulates response to anti-PD-1 immunotherapy in melanoma patients.

scientific article published on 2 November 2017

HLA-A0201 positive pancreatic cell lines: new findings and discrepancies

scientific article published on September 2006

HSP90 inhibition enhances cancer immunotherapy by upregulating interferon response genes

scientific article published on 6 September 2017

Harnessing the Power of the Immune System to Target Cancer ⬇️

scientific article published on October 22, 2012

High-Throughput Screening of Myxoid Liposarcoma Cell Lines: Survivin Is Essential for Tumor Growth

scientific article published on 24 June 2017

Higher mortality in men from COVID19 infection-understanding the factors that drive the differences between the biological sexes

scientific article published on 24 April 2020

Hypoxia-Driven Mechanism of Vemurafenib Resistance in Melanoma

scientific article published on 25 July 2016

IFN-alpha enhances peptide vaccine-induced CD8+ T cell numbers, effector function, and antitumor activity

scientific article published on June 2009

IL-2 analogues: novel agents circumventing the expansion of T regulatory cells while promoting NK cell activation during IL-2 therapy

scientific article published on 7 November 2013

IL-2 therapy promotes suppressive ICOS+ Treg expansion in melanoma patients

scientific article published on January 2014

IL-21 synergizes with IL-7 to augment expansion and anti-tumor function of cytotoxic T cells

scientific article

IL17A Blockade Successfully Treated Psoriasiform Dermatologic Toxicity from Immunotherapy

scientific article published on 17 April 2019

IL2 Variant Circumvents ICOS+ Regulatory T-cell Expansion and Promotes NK Cell Activation

scientific article published on 3 October 2016

IMCT-07THERAPEUTIC OUTCOMES OF INTRATHECAL INTERLEUKIN-2 IN METASTATIC MELANOMA PATIENTS WITH LEPTOMENINGEAL DISEASE (LMD).

scientific article

Identification of predictive biomarker signatures in melanoma tumors associated with response to tumor-infiltrating lymphocyte (TIL) therapy

scientific article published on 7 November 2013

Immediate triggering of 4-1BB co-stimulation during initiation of tumor-infiltrating lymphocyte (TIL) expansion from melanoma tumors accelerates CD8+ T-cell outgrowth and tumor specificity

scientific article published on 7 November 2013

Immune profiling of uveal melanoma identifies a potential signature associated with response to immunotherapy

scientific article published on 01 November 2020

Immunization of patients with metastatic melanoma using both class I- and class II-restricted peptides from melanoma-associated antigens

scientific article

Immuno-genomic landscape of osteosarcoma

scientific article published on 21 February 2020

Immunosuppression in melanoma immunotherapy: potential opportunities for intervention

scientific article

Immunotherapy of melanoma: an update

scientific article published on January 2011

Impact of clinical and pathologic features on tumor-infiltrating lymphocyte expansion from surgically excised melanoma metastases for adoptive T-cell therapy

scientific article

Improving antitumor immune responses by circumventing immunoregulatory cells and mechanisms

scientific article published on August 2006

In vivo antitumor activity of interleukin 21 mediated by natural killer cells

scientific article published on 01 December 2003

Inability to immunize patients with metastatic melanoma using plasmid DNA encoding the gp100 melanoma-melanocyte antigen.

scientific article

Incidence, patterns of progression, and outcomes of preexisting and newly discovered brain metastases during treatment with anti-PD-1 in patients with metastatic melanoma

scientific article published on 09 August 2019

Increased Tumor Glycolysis Characterizes Immune Resistance to Adoptive T Cell Therapy

scientific article published on 05 April 2018

Induction of CD4(+) T cell-dependent antitumor immunity by TAT-mediated tumor antigen delivery into dendritic cells

scientific article

Induction of NKG2D Ligands on Solid Tumors Requires Tumor-Specific CD8+ T Cells and Histone Acetyltransferases

scientific article published on 21 February 2017

Induction of systemic anti-melanoma immunity through intratumoral TLR-7/8 activation.

scientific article published on 6 November 2014

Infliximab associated with faster symptom resolution compared with corticosteroids alone for the management of immune-related enterocolitis

scholarly article by Daniel H Johnson et al published 11 October 2018 in Journal for Immunotherapy of Cancer

Inhibition of the B7-H3 immune checkpoint limits tumor growth by enhancing cytotoxic lymphocyte function

scientific article

Initiative for Molecular Profiling and Advanced Cancer Therapy (IMPACT): An MD Anderson Precision Medicine Study

scientific article published on 08 September 2017

Innovations and challenges in melanoma: summary statement from the first Cambridge conference

scientific article published on 01 April 2006

Insights from immuno-oncology: the Society for Immunotherapy of Cancer Statement on access to IL-6-targeting therapies for COVID-19

scientific article published on 01 April 2020

Integrated molecular analysis of tumor biopsies on sequential CTLA-4 and PD-1 blockade reveals markers of response and resistance.

scientific article

Intralymphatic dendritic cell vaccination induces tumor antigen-specific, skin-homing T lymphocytes

scientific article

Intrathecal Administration of Tumor-Infiltrating Lymphocytes Is Well Tolerated in a Patient with Leptomeningeal Disease from Metastatic Melanoma: A Case Report

scientific article published on 27 July 2015

Intratumoral CD40 activation and checkpoint blockade induces T cell-mediated eradication of melanoma in the brain.

scientific article published on 13 November 2017

Less yin, more yang: confronting the barriers to cancer immunotherapy

scientific article published on September 2007

Long-term outcome in BRAF(V600E) melanoma patients treated with vemurafenib: Patterns of disease progression and clinical management of limited progression

scientific article published on 13 May 2015

Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy

scientific article published on 09 September 2016

Loss of PTEN Promotes Resistance to T Cell-Mediated Immunotherapy.

scientific article published on 8 December 2015

Lovastatin Inhibits T-cell Proliferation While Preserving the Cytolytic Function of EBV, CMV, and MART-1-specific CTLs ⬇️

scientific article published on November 1, 2010

Lymphocyte-specific kinase expression is a prognostic indicator in ovarian cancer and correlates with a prominent B cell transcriptional signature

scientific article published on 12 September 2019

MAGE-A3 is a Clinically Relevant Target in Undifferentiated Pleomorphic Sarcoma/Myxofibrosarcoma

scientific article published on 15 May 2019

MART-1-specific melanoma tumor-infiltrating lymphocytes maintaining CD28 expression have improved survival and expansion capability following antigenic restimulation in vitro

scientific article published on 30 November 2009

MHC class I and class II presentation of tumor antigen in retrovirally and adenovirally transduced dendritic cells

scientific article published on November 2002

Macrophage depletion through colony stimulating factor 1 receptor pathway blockade overcomes adaptive resistance to anti-VEGF therapy.

scientific article published on 24 August 2017

Manipulating the tumor microenvironment ex vivo for enhanced expansion of tumor-infiltrating lymphocytes for adoptive cell therapy.

scientific article published on 3 December 2014

Melanoma and immunotherapy bridge 2015 : Naples, Italy. 1-5 December 2015

scientific article

Melanoma cells express ICOS ligand to promote the activation and expansion of T-regulatory cells ⬇️

scientific article published on November 23, 2010

Metastatic Melanoma Patient Had a Complete Response with Clonal Expansion after Whole Brain Radiation and PD-1 Blockade.

scientific article published on 6 January 2017

Minicircle DNA is Superior to Plasmid DNA in Eliciting Antigen-specific CD8+ T-cell Responses ⬇️

scientific article published on May 21, 2013

Mobilization of dendritic cell precursors in patients with cancer by flt3 ligand allows the generation of higher yields of cultured dendritic cells

scientific article published on May 2002

Modification of BTLA signaling motifs in TIL exhibits positive signals that mediate anti-tumor control

scientific article published on 4 November 2015

Molecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases

scientific article published on 20 February 2019

Multifaceted role of BTLA in the control of CD8+ T cell fate after antigen encounter

scientific article

NRAS mutation status is an independent prognostic factor in metastatic melanoma

scientific article

Nanoparticle formulated alpha-galactosylceramide activates NKT cells without inducing anergy

scientific article

Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma

scientific article published on 8 October 2018

Neoadjuvant plus adjuvant dabrafenib and trametinib versus standard of care in patients with high-risk, surgically resectable melanoma: a single-centre, open-label, randomised, phase 2 trial

scientific article

New insights on the role of CD8+CD57+T-cells in cancer ⬇️

scientific article published on September 1, 2012

Nivolumab and Ipilimumab in Metastatic Uveal Melanoma: Results From a Single-Arm Phase II Study

scientific article published on 30 October 2020

Novel Treatments in Development for Melanoma.

scientific article

Novel algorithmic approach predicts tumor mutation load and correlates with immunotherapy clinical outcomes using a defined gene mutation set.

scientific article

Oncogenic BRAF(V600E) promotes stromal cell-mediated immunosuppression via induction of interleukin-1 in melanoma

scientific article

Overexpressed PRAME is a potential immunotherapy target in sarcoma subtypes

scientific article

Overexpression of interleukin 21 induces expansion of hematopoietic progenitor cells

scientific article published on 01 October 2006

PD-1 blockade enhances T-cell migration to tumors by elevating IFN-γ inducible chemokines

scientific article

PD-L1 expression in triple-negative breast cancer

scientific article published on 10 January 2014

Parallel profiling of immune infiltrate subsets in uveal melanoma versus cutaneous melanoma unveils similarities and differences: A pilot study.

scientific article

Pathways and therapeutic targets in melanoma

scientific article

Pelvic computed tomography scans for surveillance in patients with primary melanoma in the head and neck ⬇️

scientific article published on 01 April 2011

Persistent antigen at vaccination sites induces tumor-specific CD8⁺ T cell sequestration, dysfunction and deletion

scientific article published on 3 March 2013

Perspectives in melanoma: meeting report from the "Melanoma Bridge" (December 5th-7th, 2019, Naples, Italy)

scientific article published on 07 September 2020

Pharmacokinetics and Safety of Marqibo (Vincristine Sulfate Liposomes Injection) in Cancer Patients With Impaired Liver Function ⬇️

scientific article published on October 26, 2010

Phase 2 open-label study of weekly docosahexaenoic acid-paclitaxel in cutaneous and mucosal metastatic melanoma patients.

scientific article

Phase 2 open-label study of weekly docosahexaenoic acid–paclitaxel in patients with metastatic uveal melanoma ⬇️

scientific article published on December 1, 2010

Phase I Study of the BRAF Inhibitor Vemurafenib in Combination With the Mammalian Target of Rapamycin Inhibitor Everolimus in Patients With BRAF-Mutated Malignancies

scientific article published on 13 September 2018

Phase I safety study of lenalidomide and dacarbazine in patients with metastatic melanoma previously untreated with systemic chemotherapy ⬇️

scientific article published on December 1, 2010

Phase I study of the combination of docetaxel, temozolomide and cisplatin in patients with metastatic melanoma

scientific article

Phase I study of the combination of sorafenib and temsirolimus in patients with metastatic melanoma

scientific article

Phase I study of the intravenous administration of attenuated Salmonella typhimurium to patients with metastatic melanoma

scientific article

Phase I trial of biochemotherapy with cisplatin, temozolomide, and dose escalation of nab-paclitaxel combined with interleukin-2 and interferon-α in patients with metastatic melanoma

scientific article

Phase I/II Study of Hepatic Arterial Infusion of Nab-paclitaxel in Patients With Metastatic Melanoma to the Liver

scientific article published on 05 March 2018

Phase I/II study of a cisplatin-taxol-dacarbazine regimen in metastatic melanoma.

scientific article

Phase I/II study of the antibody-drug conjugate glembatumumab vedotin in patients with advanced melanoma

scientific article published on 29 September 2014

Phase II study of the MEK1/MEK2 inhibitor Trametinib in patients with metastatic BRAF-mutant cutaneous melanoma previously treated with or without a BRAF inhibitor

scientific article published on 17 December 2012

Pilot study of intratumoral (IT) cryoablation (cryo) in combination with systemic checkpoint blockade in patients with metastatic melanoma (MM).

scientific article published on 4 November 2015

Plasmacytoid dendritic cells induce NK cell-dependent, tumor antigen-specific T cell cross-priming and tumor regression in mice

scientific article published in March 2008

Plasmacytoid dendritic cells synergize with myeloid dendritic cells in the induction of antigen-specific antitumor immune responses

scientific article published on 01 February 2007

Potential clinical application of tumor-infiltrating lymphocyte therapy for ovarian epithelial cancer prior or post-resistance to chemotherapy

scientific article published on 10 October 2019

Preclinical development of tumor-infiltrating lymphocyte therapy for ovarian cancer.

scientific article published on 4 November 2015

Predictive Factors for the Development of Brain Metastasis in Advanced Unresectable Metastatic Melanoma ⬇️

scientific article published on 01 December 2011

Predictive immune biomarker signatures in the tumor microenvironment of melanoma metastases associated with tumor-infiltrating lymphocyte (TIL) therapy

scientific article published on 6 November 2014

Presentation of tumor antigens by dendritic cells genetically modified with viral and nonviral vectors

scientific article

Prognostic and biologic significance of high LCK expression in ovarian cancer

scientific article published on 4 November 2015

Prognostic factors for survival in melanoma patients with brain metastases ⬇️

scientific article published on October 19, 2010

Prognostic factors that determine the long-term survival of patients with unresectable metastatic melanoma

scientific article published in July 2008

Prospective Analysis of Adoptive TIL Therapy in Patients with Metastatic Melanoma: Response, Impact of Anti-CTLA4, and Biomarkers to Predict Clinical Outcome

Publisher Correction: Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma

scientific article published on 01 December 2018

RNA editing derived epitopes function as cancer antigens to elicit immune responses

scientific article published in Nature Communications

Radiation Followed by OX40 Stimulation Drives Local and Abscopal Antitumor Effects in an Anti-PD1-Resistant Lung Tumor Model.

scientific article published on 21 May 2018

Radiologic manifestations of immune-related adverse events in patients with metastatic melanoma undergoing anti-CTLA-4 antibody therapy

scientific article published in December 2011

Randomized study of high-dose and low-dose interleukin-2 in patients with metastatic renal cancer

scientific article

Rapid tumor regression in an Asian lung cancer patient following personalized neo-epitope peptide vaccination

scientific article

Recombinant fowlpox viruses encoding the anchor-modified gp100 melanoma antigen can generate antitumor immune responses in patients with metastatic melanoma

scientific article

Redirecting migration of T cells to chemokine secreted from tumors by genetic modification with CXCR2

scientific article published on 01 November 2002

Reduced adenosine-to-inosine miR-455-5p editing promotes melanoma growth and metastasis

scientific article

Regulation of B cell differentiation and plasma cell generation by IL-21, a novel inducer of Blimp-1 and Bcl-6

scientific article

Retrospective review of metastatic melanoma patients with leptomeningeal disease treated with intrathecal interleukin-2.

scientific article published on 24 January 2018

Risk of intracranial hemorrhage with anticoagulation therapy in melanoma patients with brain metastases ⬇️

scientific article published on August 1, 2012

SLC45A2: A Melanoma Antigen with High Tumor Selectivity and Reduced Potential for Autoimmune Toxicity.

scientific article

STING activation of tumor endothelial cells initiates spontaneous and therapeutic antitumor immunity

scientific article

Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer

scientific article (publication date: 28 June 2012)

Selective inhibition of autoimmune exacerbation while preserving the anti-tumor clinical benefit using IL-6 blockade in a patient with advanced melanoma and Crohn's disease: a case report

scientific article published on 5 September 2016

Single-cell motility and gene expression signature as predictors of the overall survival of act in melanoma patients.

scientific article published on 4 November 2015

Spatially resolved analyses link genomic and immune diversity and reveal unfavorable neutrophil activation in melanoma

scientific article published on 15 April 2020

Specific lymphocyte subsets predict response to adoptive cell therapy using expanded autologous tumor-infiltrating lymphocytes in metastatic melanoma patients

scientific article

Strategies for improving the management of immune-related adverse events

scientific article published on 01 December 2020

Strong emerging rationale for combining oncogene-targeted agents with immunotherapy ⬇️

scientific article published on February 1, 2013

Successful treatment of arthritis induced by checkpoint inhibitors with tocilizumab: a case series.

scientific article published on 22 August 2017

Summary of the primer on tumor immunology and the biological therapy of cancer

scientific article published on 28 January 2009

Suppression of Type I IFN Signaling in Tumors Mediates Resistance to Anti-PD-1 Treatment That Can Be Overcome by Radiotherapy

scientific article published on 7 November 2016

Survivin DNA vaccine generated specific antitumor effects in pancreatic carcinoma and lymphoma mouse models

scientific article

Synthetic Poly(L-Glutamic Acid)-conjugated CpG Exhibits Antitumor Efficacy With Increased Retention in Tumor and Draining Lymph Nodes After Intratumoral Injection in a Mouse Model of Melanoma

scientific article published on 27 September 2016

Systemic therapy for unresectable metastatic melanoma: impact of biochemotherapy on long-term survival

scientific article published in April 2008

T cell homing therapy for reducing regulatory T cells and preserving effector T cell function in large solid tumors

scientific article

T cells and T cell tumors efficiently generate antigen-specific cytotoxic T cell immunity when modified with an NKT ligand ⬇️

scientific article published on March 1, 2012

T helper 17 cells promote cytotoxic T cell activation in tumor immunity

scientific article

TGF-beta1 induces preferential rapid expansion and persistence of tumor antigen-specific CD8+ T cells for adoptive immunotherapy

scientific article published on 01 May 2010

Targeted next generation sequencing of well-differentiated/dedifferentiated liposarcoma reveals novel gene amplifications and mutations.

scientific article published on 13 April 2018

The Effect of Topoisomerase I Inhibitors on the Efficacy of T-Cell-Based Cancer Immunotherapy.

scientific article published on 18 December 2017

The RNA-binding protein MEX3B mediates resistance to cancer immunotherapy by downregulating HLA-A expression

scientific article published in March 2018

The beneficial effects of a gas-permeable flask for expansion of Tumor-Infiltrating lymphocytes as reflected in their mitochondrial function and respiration capacity

scientific article published on 5 June 2015

The clinical efficacy of combination of docetaxel and temozolomide in previously treated patients with stage IV melanoma

scientific article

The iSBTc/SITC primer on tumor immunology and biological therapy of cancer: a summary of the 2010 program ⬇️

scientific article published on January 31, 2011

The role of transcription factor Runx2 in tumor infiltrating T cells

scientific article published on 7 November 2013

Toxicity management after chimeric antigen receptor T cell therapy: one size does not fit 'ALL'.

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Transduction of tumor-specific T cells with CXCR2 chemokine receptor improves migration to tumor and antitumor immune responses

scientific article

Tumor-infiltrating lymphocyte therapy for melanoma: rationale and issues for further clinical development

scientific article published on October 2014

Uncovering a novel function of BTLA on tumor-infiltrating CD8+ T cells

scientific article published on 7 November 2013

Utilizing T-cell Activation Signals 1, 2, and 3 for Tumor-infiltrating Lymphocytes (TIL) Expansion: The Advantage Over the Sole Use of Interleukin-2 in Cutaneous and Uveal Melanoma

scientific article published on 01 November 2018

Vestigial-like 1 is a shared targetable cancer-placenta antigen expressed by pancreatic and basal-like breast cancers

scientific article published on 21 October 2020

Visualizing fewer than 10 mouse T cells with an enhanced firefly luciferase in immunocompetent mouse models of cancer

scholarly article

White Paper on Adoptive Cell Therapy for Cancer with Tumor-Infiltrating Lymphocytes: A Report of the CTEP Subcommittee on Adoptive Cell Therapy ⬇️

scientific article published on February 15, 2011

You can run but you can't hide: tracking T cells in metastatic melanoma patients treated with tumor-infiltrating lymphocytes

scientific article published on 4 November 2015

gp100 peptide vaccine and interleukin-2 in patients with advanced melanoma

scientific article

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