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Authors whose works are in public domain in at least one jurisdiction

List of works by Patrick Hwu

1-50 of 255 results

Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer

scientific article (publication date: 28 June 2012)

A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer

scientific article published on July 2003

Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes

scientific article

Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma

scientific article

Gut microbiome modulates response to anti-PD-1 immunotherapy in melanoma patients.

scientific article published on 2 November 2017

A phase I study on adoptive immunotherapy using gene-modified T cells for ovarian cancer

scientific article

BRAF inhibition is associated with enhanced melanoma antigen expression and a more favorable tumor microenvironment in patients with metastatic melanoma.

scientific article published on 10 January 2013

gp100 peptide vaccine and interleukin-2 in patients with advanced melanoma

scientific article

T helper 17 cells promote cytotoxic T cell activation in tumor immunity

scientific article

Regulation of B cell differentiation and plasma cell generation by IL-21, a novel inducer of Blimp-1 and Bcl-6

scientific article

Loss of PTEN Promotes Resistance to T Cell-Mediated Immunotherapy.

scientific article published on 8 December 2015

Randomized study of high-dose and low-dose interleukin-2 in patients with metastatic renal cancer

scientific article

Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy

scientific article published on 09 September 2016

PD-L1 Expression in Triple-Negative Breast Cancer

scientific article published on January 10, 2014

NRAS mutation status is an independent prognostic factor in metastatic melanoma

scientific article

Chimeric antigen receptor T-cell therapy - assessment and management of toxicities.

scientific article

Analysis of Immune Signatures in Longitudinal Tumor Samples Yields Insight into Biomarkers of Response and Mechanisms of Resistance to Immune Checkpoint Blockade

scientific article published on 14 June 2016

Phase I study of the intravenous administration of attenuated Salmonella typhimurium to patients with metastatic melanoma

scientific article

Phase II study of the MEK1/MEK2 inhibitor Trametinib in patients with metastatic BRAF-mutant cutaneous melanoma previously treated with or without a BRAF inhibitor

scientific article published on 17 December 2012

Persistent antigen at vaccination sites induces tumor-specific CD8⁺ T cell sequestration, dysfunction and deletion

scientific article published on 3 March 2013

PD-1 blockade enhances T-cell migration to tumors by elevating IFN-γ inducible chemokines

scientific article

A phase I study of nonmyeloablative chemotherapy and adoptive transfer of autologous tumor antigen-specific T lymphocytes in patients with metastatic melanoma

scientific article

Specific lymphocyte subsets predict response to adoptive cell therapy using expanded autologous tumor-infiltrating lymphocytes in metastatic melanoma patients

scientific article

Prognostic factors for survival in melanoma patients with brain metastases

scientific article published on October 19, 2010

BRAF Inhibition Increases Tumor Infiltration by T cells and Enhances the Antitumor Activity of Adoptive Immunotherapy in Mice

scientific article published on November 30, 2012

Epithelial-Mesenchymal Transition Is Associated with a Distinct Tumor Microenvironment Including Elevation of Inflammatory Signals and Multiple Immune Checkpoints in Lung Adenocarcinoma

scientific article published on 5 February 2016

Integrated molecular analysis of tumor biopsies on sequential CTLA-4 and PD-1 blockade reveals markers of response and resistance.

scientific article

Oncogenic BRAF(V600E) promotes stromal cell-mediated immunosuppression via induction of interleukin-1 in melanoma

scientific article

Visualizing fewer than 10 mouse T cells with an enhanced firefly luciferase in immunocompetent mouse models of cancer

scholarly article

Plasmacytoid dendritic cells induce NK cell-dependent, tumor antigen-specific T cell cross-priming and tumor regression in mice

scientific article published in March 2008

Redirecting migration of T cells to chemokine secreted from tumors by genetic modification with CXCR2

scientific article published on 01 November 2002

A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade

article

STING activation of tumor endothelial cells initiates spontaneous and therapeutic antitumor immunity

scientific article

Activity of dasatinib against L576P KIT mutant melanoma: molecular, cellular, and clinical correlates

scientific article

Defining the critical hurdles in cancer immunotherapy

scientific article published on 14 December 2011

Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma

scientific article published on 8 October 2018

Association of body-mass index and outcomes in patients with metastatic melanoma treated with targeted therapy, immunotherapy, or chemotherapy: a retrospective, multicohort analysis.

scientific article published on 12 February 2018

Adoptive T-cell therapy using autologous tumor-infiltrating lymphocytes for metastatic melanoma: current status and future outlook

scientific article

Pathways and therapeutic targets in melanoma

scientific article published on April 15, 2014

Transduction of tumor-specific T cells with CXCR2 chemokine receptor improves migration to tumor and antitumor immune responses

scientific article

IL-2 therapy promotes suppressive ICOS+ Treg expansion in melanoma patients

scientific article published on January 1, 2014

Reduced adenosine-to-inosine miR-455-5p editing promotes melanoma growth and metastasis

scientific article

Dendritic cells strongly boost the antitumor activity of adoptively transferred T cells in vivo.

scientific article

Suppression of Type I IFN Signaling in Tumors Mediates Resistance to Anti-PD-1 Treatment That Can Be Overcome by Radiotherapy

scientific article published on 7 November 2016

In vivo antitumor activity of interleukin 21 mediated by natural killer cells

scientific article published on 01 December 2003

Correlation of NRAS Mutations With Clinical Response to High-dose IL-2 in Patients With Advanced Melanoma

scientific article published on January 1, 2012

Beyond BRAF(V600): clinical mutation panel testing by next-generation sequencing in advanced melanoma

scientific article

Radiologic manifestations of immune-related adverse events in patients with metastatic melanoma undergoing anti-CTLA-4 antibody therapy

scientific article published in December 2011

Increased Tumor Glycolysis Characterizes Immune Resistance to Adoptive T Cell Therapy

scientific article published on 05 April 2018

Immunization of patients with metastatic melanoma using both class I- and class II-restricted peptides from melanoma-associated antigens

scientific article