Search filters

List of works by Karl Swann

7 A Novel Protein for Ca2+ Signaling at Fertilization

scientific article published on January 1, 1998

Activation of Ca(2+)-dependent currents in cultured rat dorsal root ganglion neurones by a sperm factor and cyclic ADP-ribose ⬇️

scientific article published on December 1, 1992

An endogenous green fluorescent protein-photoprotein pair in Clytia hemisphaerica eggs shows co-targeting to mitochondria and efficient bioluminescence energy transfer

scientific article

Antigen unmasking enhances visualization efficacy of the oocyte activation factor, phospholipase C zeta, in mammalian sperm.

scientific article published on 08 December 2016

Binding of phosphoinositide-specific phospholipase C-zeta (PLC-zeta) to phospholipid membranes: potential role of an unstructured cluster of basic residues

scientific article published on 12 April 2007

Ca(2+) dynamics in oocytes from naturally-aged mice

scientific article published on 20 January 2016

Ca(2+) oscillations and sperm factors at fertilization in mammals

scientific article

Ca2+ oscillations stimulate an ATP increase during fertilization of mouse eggs.

scientific article

Cell cycle-dependent Ca2+ oscillations in mouse embryos are regulated by nuclear targeting of PLCzeta.

scientific article

Chimeras of sperm PLCζ reveal disparate protein domain functions in the generation of intracellular Ca2+ oscillations in mammalian eggs at fertilization

scientific article published on 23 October 2013

Cloning of a novel phospholipase C-delta isoform from pacific purple sea urchin (Strongylocentrotus purpuratus) gametes and its expression during early embryonic development

scientific article published on January 2004

Composition of sea urchin egg homogenate determines its potency to inositol trisphosphate and cyclic ADPRibose-induced Ca2+ release

scientific article published on 5 July 2007

Divergent effect of mammalian PLCζ in generating Ca²⁺ oscillations in somatic cells compared with eggs

scientific article

Dynamic label-free imaging of lipid droplets and their link to fatty acid and pyruvate oxidation in mouse eggs

scientific article published on 05 July 2019

Dynamic shapes of the zygote and two-cell mouse and human

scientific article published on 15 December 2021

Egg Activation at Fertilization by a Soluble Sperm Protein.

scientific article

Electrical-assisted microinjection for analysis of fertilization and cell division in mammalian oocytes and early embryos ⬇️

scientific article published on 01 January 2018

Essential Role of the EF-hand Domain in Targeting Sperm Phospholipase Cζ to Membrane Phosphatidylinositol 4,5-Bisphosphate (PIP2).

scientific article

Fertilization differently affects the levels of cyclin B1 and M-phase promoting factor activity in maturing and metaphase II mouse oocytes.

scientific article

Follicle-stimulating hormone induces a gap junction-dependent dynamic change in [cAMP] and protein kinase a in mammalian oocytes.

scientific article

Functional disparity between human PAWP and PLCζ in the generation of Ca2+ oscillations for oocyte activation

scientific article

Human PLCζ exhibits superior fertilization potency over mouse PLCζ in triggering the Ca(2+) oscillations required for mammalian oocyte activation

scientific article

Internal calcium release and activation of sea urchin eggs by cGMP are independent of the phosphoinositide signaling pathway ⬇️

scientific article published on March 1, 1992

Is PAWP the "real" sperm factor?

scientific article published on May 2015

Male infertility-linked point mutation disrupts the Ca2+ oscillation-inducing and PIP(2) hydrolysis activity of sperm PLCζ.

scientific article

Male infertility-linked point mutation reveals a vital binding role for the C2 domain of sperm PLCζ.

scientific article published on 7 March 2017

Measuring Ca2+ Oscillations in Mammalian Eggs ⬇️

scientific article published on January 1, 2013

Mitochondria and lipid metabolism in mammalian oocytes and early embryos

scientific article published on 01 January 2019

Molecular triggers of egg activation at fertilization in mammals

scientific article

Novel regulation of PLCζ activity via its XY-linker

scientific journal article

PLC zeta: a sperm-specific trigger of Ca(2+) oscillations in eggs and embryo development

scientific journal article

PLC? and the initiation of Ca2+ oscillations in fertilizing mammalian eggs ⬇️

scientific article published on 05 December 2012

PLCzeta, a sperm-specific PLC and its potential role in fertilization

scientific article

PLCζ Induced Ca2+ Oscillations in Mouse Eggs Involve a Positive Feedback Cycle of Ca2+ Induced InsP3 Formation From Cytoplasmic PIP2.

scientific article published on 3 April 2018

PLCζ causes Ca(2+) oscillations in mouse eggs by targeting intracellular and not plasma membrane PI(4,5)P(2).

scientific article

PLCζ or PAWP: revisiting the putative mammalian sperm factor that triggers egg activation and embryogenesis

scientific article

Phospholipase C-ζ-induced Ca2+ oscillations cause coincident cytoplasmic movements in human oocytes that failed to fertilize after intracytoplasmic sperm injection

scientific article

Phospholipase Cζ binding to PtdIns(4,5)P2 requires the XY-linker region

scientific article

Phospholipase Cζ rescues failed oocyte activation in a prototype of male factor infertility

scientific article published on 21 September 2012

Phospholipid binding properties and functional characterization of a sea urchin phospholipase Cdelta in urchin and mouse eggs

scientific article published on 18 April 2007

Presence and localization of oscillin in human spermatozoa in relation to the integrity of the sperm membrane ⬇️

scientific article published on February 27, 1998

Quantitative imaging of lipids in live mouse oocytes and early embryos using CARS microscopy

scientific article

Redistribution of mitochondria leads to bursts of ATP production during spontaneous mouse oocyte maturation.

scientific article

Regulation of cytosolic and mitochondrial ATP levels in mouse eggs and zygotes.

scientific article

Regulation of diacylglycerol production and protein kinase C stimulation during sperm- and PLCzeta-mediated mouse egg activation

scientific article

Rescue of failed oocyte activation after ICSI in a mouse model of male factor infertility by recombinant phospholipase Cζ

scientific article

Rhythmic actomyosin-driven contractions induced by sperm entry predict mammalian embryo viability

scientific article

Role of phospholipase C-zeta domains in Ca2+-dependent phosphatidylinositol 4,5-bisphosphate hydrolysis and cytoplasmic Ca2+ oscillations

scientific article published on 6 July 2005

Soluble sperm factors and Ca2+ release in eggs at fertilization

scientific article published on January 1, 1996

Sperm PLCζ: from structure to Ca2+ oscillations, egg activation and therapeutic potential.

scientific article published on 21 October 2013

Sperm-induced Ca2+ release during egg activation in mammals.

scientific article published on 21 April 2014

Sperm-induced currents at fertilization in sea urchin eggs injected with EGTA and neomycin

scientific article published on June 1, 1992

Sperm-specific post-acrosomal WW-domain binding protein (PAWP) does not cause Ca2+ release in mouse oocytes.

scientific article

Sperm-triggered [Ca2+] oscillations and Ca2+ homeostasis in the mouse egg have an absolute requirement for mitochondrial ATP production.

scientific article

Starting a new life: sperm PLC-zeta mobilizes the Ca2+ signal that induces egg activation and embryo development: an essential phospholipase C with implications for male infertility.

scientific article

Stimulation of repetitive calcium transients in mouse eggs ⬇️

scientific article published on March 1, 1995

The dynamics of MAPK inactivation at fertilization in mouse eggs.

scientific article

The dynamics of PKC-induced phosphorylation triggered by Ca2+ oscillations in mouse eggs

scientific article published on January 2013

The dynamics of calcium oscillations that activate mammalian eggs

scientific article published on January 2008

The dynamics of plasma membrane PtdIns(4,5)P(2) at fertilization of mouse eggs.

scientific article published in May 2002

The effects of a Ca2+ chelator and heavy-metal-ion chelators upon Ca2+ oscillations and activation at fertilization in mouse eggs suggest a role for repetitive Ca2+ increases ⬇️

scientific article published on October 15, 1998

The role of ATP in the differential ability of Sr2+ to trigger Ca2+ oscillations in mouse and human eggs

scientific article published on 05 January 2021

The role of Ca2+ in oocyte activation during In Vitro fertilization: Insights into potential therapies for rescuing failed fertilization

scientific article published on 08 May 2018

The soluble sperm factor that activates the egg: PLCzeta and beyond

scientific article published on 01 July 2020

The sperm phospholipase C-ζ and Ca2+ signalling at fertilization in mammals.

scientific article published on February 2016

Use of luciferase chimaera to monitor PLCzeta expression in mouse eggs

scientific article

Paulina is supported by:

About Paulina

Help