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List of works by Sandro Santagata

A case of molecularly profiled extraneural medulloblastoma metastases in a child

scientific article published on 17 January 2018

A prognostic cytogenetic scoring system to guide the adjuvant management of patients with atypical meningioma

scientific article

ARID1A and TERT promoter mutations in dedifferentiated meningioma

scientific article published on 18 March 2015

Adjuvant radiation therapy, local recurrence, and the need for salvage therapy in atypical meningioma

scientific article

An update on the CNS manifestations of neurofibromatosis type 2

scientific article published on 04 June 2019

Anaplastic variant of medulloblastoma mimicking a vestibular schwannoma

scientific article published on 5 December 2006

Angiomatous meningiomas have a distinct genetic profile with multiple chromosomal polysomies including polysomy of chromosome 5.

scientific article published in November 2014

Antigen dominance hierarchies shape TCF1+ progenitor CD8 T cell phenotypes in tumors

scientific article published on 16 September 2021

Application of desorption electrospray ionization mass spectrometry imaging in breast cancer margin analysis

scientific article

Artifacts to avoid while taking advantage of top-down mass spectrometry based detection of protein S-thiolation

scientific article published on 17 April 2014

Author Correction: Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer

scientific article published on 18 May 2020

Author Correction: Mitochondrial metabolism promotes adaptation to proteotoxic stress

scientific article published on 01 July 2019

BAP1 mutations in high-grade meningioma: implications for patient care

scientific article published on 8 May 2017

BM-07GENOMIC CHARACTERIZATION OF BRAIN METASTASES REVEALS BRANCHED EVOLUTION AND METASTASIS-SPECIFIC MUTATIONS

BMET-04LEPTOMENINGEAL CARCINOMATOSIS IN MELANOMA.

scientific article published on 9 November 2015

BRAF V600E mutations are common in pleomorphic xanthoastrocytoma: diagnostic and therapeutic implications

scientific article

CRAN-11. MULTIPLEXED IMMUNOFLUORESCENCE REVEALS POTENTIAL PD-1/PD-L1 PATHWAY VULNERABILITIES IN CRANIOPHARYNGIOMA

CRX is a diagnostic marker of retinal and pineal lineage tumors

scientific article

Case-Based Review: meningioma

scientific article published on 13 January 2016

Chaperones as thermodynamic sensors of drug-target interactions reveal kinase inhibitor specificities in living cells

scientific article published on 30 June 2013

Checkpoint inhibition in meningiomas

scientific article published on June 2016

Clinical and radiographic response following targeting of BCAN-NTRK1 fusion in glioneuronal tumor.

scientific article published on 20 March 2017

Clinical identification of oncogenic drivers and copy number alterations in pituitary tumors.

scientific article published on 08 May 2017

Clinical implementation of integrated whole-genome copy number and mutation profiling for glioblastoma

scientific article

Clinical multiplexed exome sequencing distinguishes adult oligodendroglial neoplasms from astrocytic and mixed lineage gliomas

scientific article published on September 2014

Clinical targeted exome-based sequencing in combination with genome-wide copy number profiling: precision medicine analysis of 203 pediatric brain tumors.

scientific article published on 19 January 2017

Comparative analysis of germ cell transcription factors in CNS germinoma reveals diagnostic utility of NANOG

scientific article

Comprehensive Study of the Clinical Phenotype of Germline BAP1 Variant-Carrying Families Worldwide

scientific article published on 01 December 2018

Compromising the 19S proteasome complex protects cells from reduced flux through the proteasome

scientific article

Controlled enzymatic production of astrocytic hydrogen peroxide protects neurons from oxidative stress via an Nrf2-independent pathway

scientific article

Correction to: An update on the CNS manifestations of neurofibromatosis type 2

scientific article published on 01 April 2020

Correction: Profiling Critical Cancer Gene Mutations in Clinical Tumor Samples

Correction: Profiling Critical Cancer Gene Mutations in Clinical Tumor Samples.

scientific article published in September 2010

Cross-reactivity of the BRAF VE1 antibody with epitopes in axonemal dyneins leads to staining of cilia

scientific article published on 21 November 2014

DMD genomic deletions characterize a subset of progressive/higher-grade meningiomas with poor outcome

scientific article published on 19 August 2018

DNA fragmentation simulation method (FSM) and fragment size matching improve aCGH performance of FFPE tissues

scientific article

Decreased FOXJ1 expression and its ciliogenesis programme in aggressive ependymoma and choroid plexus tumours

scientific article published on 22 December 2015

Detection of KIAA1549-BRAF fusion transcripts in formalin-fixed paraffin-embedded pediatric low-grade gliomas.

scientific article published on 30 August 2011

Diagnosis and management of craniopharyngiomas in the era of genomics and targeted therapy.

scientific article published on December 2016

Distinct genomic subclasses of high-grade/progressive meningiomas: NF2-associated, NF2-exclusive, and NF2-agnostic

scientific article published on 21 October 2020

Distinct patterns of primary and motile cilia in Rathke's cleft cysts and craniopharyngioma subtypes

scientific article published on 26 August 2016

Dramatic Response of BRAF V600E Mutant Papillary Craniopharyngioma to Targeted Therapy.

scientific article published on 23 October 2015

ENDOCRINE TUMORS: BRAF V600E mutations in papillary craniopharyngioma

scientific article

Embryonic stem cell transcription factor signatures in the diagnosis of primary and metastatic germ cell tumors.

scientific article published on June 2007

Erratum: Genomic landscape of high-grade meningiomas.

scientific article published on 4 September 2017

Exome sequencing identifies BRAF mutations in papillary craniopharyngiomas

scientific article

Expression profiles of 151 pediatric low-grade gliomas reveal molecular differences associated with location and histological subtype

scientific article

Frequent inactivating mutations of the PBAF complex gene PBRM1 in meningioma with papillary features

scientific article published on 13 May 2020

GE-05EXOME SEQUENCING REVEALS BRAF MUTATIONS IN PAPILLARY CRANIOPHARYNGIOMAS.

scientific article

GENE-09. PRECISION MEDICINE ANALYSIS OF 203 PEDIATRIC BRAIN TUMORS REVEALS CLINICALLY RELEVANT GENOMIC ALTERATIONS.

scientific article published on 31 May 2017

GENO-09LANDSCAPE OF GENOMIC ALTERATIONS IN PITUITARY ADENOMAS.

scientific article

Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets

scientific article published on 26 September 2015

Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1

scientific article published on 30 April 2013

Genomic characterization of human brain metastases identifies drivers of metastatic lung adenocarcinoma

scientific article published on 23 March 2020

Genomic landscape of high-grade meningiomas.

scientific article published on 26 April 2017

Genomic landscape of intracranial meningiomas

scientific article published on 15 January 2016

Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations

scientific article published on 20 January 2013

Germline and somatic BAP1 mutations in high-grade rhabdoid meningiomas

scientific article published on 9 November 2016

HAND1 and BARX1 Act as Transcriptional and Anatomic Determinants of Malignancy in Gastrointestinal Stromal Tumor ⬇️

scientific article published on 15 January 2021

HSF1 drives a transcriptional program distinct from heat shock to support highly malignant human cancers

scientific article

HSF1 phase transition mediates stress adaptation and cell fate decisions

scientific article published on 03 February 2020

HSF2 cooperates with HSF1 to drive a transcriptional program critical for the malignant state

scientific article published on 16 March 2022

HSP90 empowers evolution of resistance to hormonal therapy in human breast cancer models

scientific article

High levels of nuclear heat-shock factor 1 (HSF1) are associated with poor prognosis in breast cancer

scientific article published on 31 October 2011

Highly multiplexed immunofluorescence images and single-cell data of immune markers in tonsil and lung cancer

scientific article published on 17 December 2019

Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes

scientific article published on 11 July 2018

Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes

INNV-13. ALLELE: A CONSORTIUM FOR PROSPECTIVE GENOMICS AND FUNCTIONAL DIAGNOSTICS TO GUIDE PATIENT CARE AND TRIAL ANALYSIS IN NEWLY-DIAGNOSED GLIOBLASTOMA

Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer

scientific article published on 19 March 2020

Increased expression of programmed death ligand 1 (PD-L1) in human pituitary tumors

scientific article published on 15 September 2016

Increased expression of the immune modulatory molecule PD-L1 (CD274) in anaplastic meningioma

scientific article published on March 2015

Individualized Screening Trial of Innovative Glioblastoma Therapy (INSIGhT): A Bayesian Adaptive Platform Trial to Develop Precision Medicines for Patients With Glioblastoma

scientific article published on 27 March 2019

Inhibiting HSP90 to Treat Cancer: A Strategy in Evolution ⬇️

scientific article published on November 1, 2012

Integrating Genomics Into Neuro-Oncology Clinical Trials and Practice

scientific article published on 01 May 2018

Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome

scientific article

Intraoperative Magnetic Resonance Imaging in Intracranial Glioma Resection: A Single-Center, Retrospective Blinded Volumetric Study

scientific article

JAGGED1 expression is associated with prostate cancer metastasis and recurrence

scientific article

LG-02MYB-QKI REARRANGEMENTS IN ANGIOCENTRIC GLIOMA DRIVE TUMORIGENICITY THROUGH A TRIPARTITE MECHANISM.

scientific article published on 30 May 2016

Label-Free Neurosurgical Pathology with Stimulated Raman Imaging.

scientific article published on 12 April 2016

Landscape of Genomic Alterations in Pituitary Adenomas.

scientific article

Localized Metabolomic Gradients in Patient-Derived Xenograft Models of Glioblastoma

scientific article published on 25 November 2019

Loss of tumor suppressor NF1 activates HSF1 to promote carcinogenesis

scientific article

MALDI mass spectrometry imaging analysis of pituitary adenomas for near-real-time tumor delineation

scientific article published on 27 July 2015

MBRS-01. A CASE OF MOLECULARLY PROFILED EXTRANEURAL MEDULLOBLASTOMA METASTASES IN A CHILD

MCMICRO: a scalable, modular image-processing pipeline for multiplexed tissue imaging

scientific article published on 25 November 2021

MEDU-37. NEURONAL DIFFERENTIATION AND CELL-CYCLE PROGRAMS MEDIATE RESPONSE AND RESISTANCE TO BET-BROMODOMAIN INHIBITION IN MYC-DRIVEN MEDULLOBLASTOMA

MITI minimum information guidelines for highly multiplexed tissue images

scientific article published on 01 March 2022

MNGO-01A PROGNOSTIC CYTOGENETIC SCORING SYSTEM TO GUIDE THE ADJUVANT MANAGEMENT OF PATIENTS WITH ATYPICAL MENINGIOMA.

scientific article

MNGO-16ESTABLISHMENT OF A PATIENT - DERIVED ORTHOTOPIC MALIGNANT MENINGIOMA MODEL FOR THE DEVELOPMENT OF TARGETED THERAPY.

scientific article

MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism

scientific article

Mass spectrometry imaging as a tool for surgical decision-making

scientific article

Mechanisms and therapeutic implications of hypermutation in gliomas

scientific article published on 15 April 2020

Meningioma transcription factors link cell lineage with systemic metabolic cues

scientific article published on 01 September 2018

Minerva: a light-weight, narrative image browser for multiplexed tissue images

scientific article published on 15 October 2020

Mismatch repair deficiency in high-grade meningioma: a rare but recurrent event associated with dramatic immune activation and clinical response to PD-1 blockade

scientific article published on 27 November 2018

Mitochondrial metabolism promotes adaptation to proteotoxic stress

scientific article published on 27 May 2019

Molecular imaging of drug transit through the blood-brain barrier with MALDI mass spectrometry imaging

scientific article

Molecular typing of Meningiomas by Desorption Electrospray Ionization Mass Spectrometry Imaging for Surgical Decision-Making

scientific article

Multiplex Amplification Coupled with COLD-PCR and High Resolution Melting Enables Identification of Low-Abundance Mutations in Cancer Samples with Low DNA Content ⬇️

scientific article published on March 1, 2011

Multiplexed Immunofluorescence Reveals Potential PD-1/PD-L1 Pathway Vulnerabilities in Craniopharyngioma.

scientific article published on 2 March 2018

Mycosis fungoides with leptomeningeal involvement

scientific article published on December 2007

Narrative online guides for the interpretation of digital-pathology images and tissue-atlas data

scientific article published on 08 November 2021

Neuronal differentiation and cell-cycle programs mediate response to BET-bromodomain inhibition in MYC-driven medulloblastoma

scientific article published on 03 June 2019

Neuropathology of a Case With Fatal CAR T-Cell-Associated Cerebral Edema

scientific article published on 01 October 2018

New molecular targets in meningiomas: the present and the future

scientific article published on 01 December 2018

Normal cell phenotypes of breast epithelial cells provide the foundation of a breast cancer taxonomy

scientific article

Nuclear CRX and FOXJ1 Expression Differentiates Non-Germ Cell Pineal Region Tumors and Supports the Ependymal Differentiation of Papillary Tumor of the Pineal Region.

scientific article

Oncogenic PI3K mutations are as common as AKT1 and SMO mutations in meningioma

scientific article published on 28 January 2016

Osteoglycin promotes meningioma development through downregulation of NF2 and activation of mTOR signaling

scientific article published on 18 September 2017

PATH-16. MOLECULAR PATHOLOGY AND CLINICAL CHARACTERISTICS OF MMR DEFICIENCY (MMRd) IN DIFFUSE GLIOMAS

PATH-30. GENOMIC LANDSCAPE OF CENTRAL NERVOUS SYSTEM TUMORS

Phase I/II study of erlotinib and temsirolimus for patients with recurrent malignant gliomas: North American Brain Tumor Consortium trial 04-02

scientific article published on 26 January 2014

Phase II study of protracted daily temozolomide for low-grade gliomas in adults

scientific article

Potential evolution of neurosurgical treatment paradigms for craniopharyngioma based on genomic and transcriptomic characteristics

scientific article published on December 2016

Pre- and Postoperative Neratinib for HER2-Positive Breast Cancer Brain Metastases: Translational Breast Cancer Research Consortium 022

scientific article published on 22 August 2019

Profiling critical cancer gene mutations in clinical tumor samples

scientific article

Profiling of adrenocorticotropic hormone and arginine vasopressin in human pituitary gland and tumor thin tissue sections using droplet-based liquid-microjunction surface-sampling-HPLC-ESI-MS-MS

scientific article published on 18 June 2015

Qualifying antibodies for image-based immune profiling and multiplexed tissue imaging

scientific article published on 18 September 2019

RARE-08. GRADING CONSIDERATIONS FOR MENINGEAL SOLITARY FIBROUS TUMOR/HEMANGIOPERICYTOMA

article published in 2018

Radiographic prediction of meningioma grade by semantic and radiomic features

scientific article published on 16 November 2017

Rapid Mass Spectrometry Imaging to Assess the Biochemical Profile of Pituitary Tissue for Potential Intraoperative Usage

scientific article

Rapid discrimination of pediatric brain tumors by mass spectrometry imaging

scientific article published on 20 August 2018

Rapid selection of cyclic peptides that reduce alpha-synuclein toxicity in yeast and animal models

scientific article

Rapid, label-free detection of brain tumors with stimulated Raman scattering microscopy

scientific article

Rebalancing Protein Homeostasis Enhances Tumor Antigen Presentation

scientific article published on 18 June 2019

Relapsing tumefactive lesion in an adult with medulloblastoma previously treated with chemoradiotherapy and stem cell transplant.

scientific article published on 28 September 2011

Response and mechanisms of resistance to larotrectinib and selitrectinib in metastatic undifferentiated sarcoma harboring oncogenic fusion of NTRK1

scientific article published on 14 February 2020

SYLARAS: A Platform for the Statistical Analysis and Visual Display of Systemic Immunoprofiling Data and Its Application to Glioblastoma

scientific article published on 03 September 2020

Scope2Screen: Focus+Context Techniques for Pathology Tumor Assessment in Multivariate Image Data

scientific article published on 24 December 2021

Single cell spatial analysis reveals the topology of immunomodulatory purinergic signaling in glioblastoma

scientific article published in 2022

Single-cell tumor-immune microenvironment of BRCA1/2 mutated high-grade serous ovarian cancer

scientific article published in 2022

Sporadic hemangioblastomas are characterized by cryptic VHL inactivation

scientific article

Structure-activity relationships for withanolides as inducers of the cellular heat-shock response

scientific article published on 25 March 2014

Successful Treatment of a Progressive BRAF V600E-Mutated Anaplastic Pleomorphic Xanthoastrocytoma With Vemurafenib Monotherapy

scientific article published on 4 August 2014

Suppression of 19S proteasome subunits marks emergence of an altered cell state in diverse cancers.

scientific article published on 27 December 2016

Susan Lindquist (1949-2016).

scientific article

Targeted sequencing of SMO and AKT1 in anterior skull base meningiomas

scientific article published on 25 November 2016

Targeted treatment of papillary craniopharyngiomas harboring BRAF V600E mutations

scientific article published on 17 July 2019

Targeting immunosuppressive macrophages overcomes PARP inhibitor resistance in BRCA1-associated triple-negative breast cancer

scientific article published on 14 December 2020

Taxonomy of breast cancer based on normal cell phenotype predicts outcome.

scientific article published on 27 January 2014

Telomere length alterations and ATRX/DAXX loss in pituitary adenomas

scientific article published on 18 March 2020

The Effect of Me2+ Cofactors at the Initial Stages of V(D)J Recombination ⬇️

scientific article published on June 26, 1998

The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution

scientific article published on 01 April 2020

The Spatial Landscape of Progression and Immunoediting in Primary Melanoma at Single-Cell Resolution

scientific article published in 2022

The impact of histopathology and NAB2-STAT6 fusion subtype in classification and grading of meningeal solitary fibrous tumor/hemangiopericytoma

scientific article published on 24 December 2018

The master regulator of the cellular stress response (HSF1) is critical for orthopoxvirus infection

scientific article (publication date: February 2014)

The reprogramming of tumor stroma by HSF1 is a potent enabler of malignancy

scientific article

Tight coordination of protein translation and HSF1 activation supports the anabolic malignant state

scientific article

Treatment of brain metastases in the modern genomic era.

scientific article

Uncovering the links between systemic hormones and oncogenic signaling in the pathogenesis of meningioma

scientific article published on 15 January 2018

Updates in prognostic markers for gliomas

scientific article published on 01 November 2018

Using the heat-shock response to discover anticancer compounds that target protein homeostasis

scientific article published on 30 November 2011

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