List of works by Takashi Shimizu

A Proinflammatory Response of Bovine Endometrial Epithelial Cells to Active Sperm In Vitro.

scientific article published on 16 January 2018

Acceleration of follicular development by administration of vascular endothelial growth factor in cycling female rats

scientific article

Accumulation of eosinophils in the infundibulum of the bovine oviduct just after ovulation

scientific article

An acute-phase protein as a regulator of sperm survival in the bovine oviduct: alpha 1-acid-glycoprotein impairs neutrophil phagocytosis of sperm in vitro

scientific article

Angiogenesis and microvasculature in the female reproductive organs: physiological and pathological implications

scientific article published on January 2012

Angiotensin II increases sperm phagocytosis by neutrophils in vitro: A possible physiological role in the bovine oviduct.

scientific article published on 14 July 2016

Apelin and APJ receptor expression in granulosa and theca cells during different stages of follicular development in the bovine ovary: Involvement of apoptosis and hormonal regulation

scientific article published on 24 January 2009

Association among endometrial hyperemia, uterine bacterial infection, and characteristics of large ovarian follicles in dairy cows

scientific article published on 25 July 2019

Association of rumen fill score and energy status during the close-up dry period with conception at first artificial insemination in dairy cows

scientific article published on 25 January 2016

BMP-4 suppresses progesterone production by inhibiting histone H3 acetylation of StAR in bovine granulosa cells in vitro ⬇️

scientific article published on November 12, 2010

Bone morphogenetic protein (BMP)-4 and BMP-7 suppress granulosa cell apoptosis via different pathways: BMP-4 via PI3K/PDK-1/Akt and BMP-7 via PI3K/PDK-1/PKC.

scientific article

Bone morphogenetic protein 4 (BMP-4) and BMP-7 induce vascular endothelial growth factor expression in bovine granulosa cells

scientific article published on 27 June 2012

Caffeine promotes premature chromosome condensation formation and in vitro development in porcine reconstructed embryos via a high level of maturation promoting factor activity during nuclear transfer.

scientific article published in September 2005

Changes in plasma metabolic hormone concentrations during the ovarian cycles of Japanese black and holstein cattle

scientific article published on 29 November 2006

Changes in the messenger RNA expressions of the endothelin-1 and angiotensin systems in mature follicles of the superovulated bovine ovary

scientific article published on 14 March 2007

Changes of leukocyte counts and expression of pro- and anti-inflammatory cytokines in peripheral leukocytes in periparturient dairy cows with retained fetal membranes

scientific article published on 29 June 2018

Changes of mRNA expression of vascular endothelial growth factor, angiopoietins and their receptors during the periovulatory period in eCG/hCG-treated immature female rats

scientific journal article

Changes of messenger RNA expression of angiogenic factors and related receptors during follicular development in gilts

scientific article published on 01 December 2002

Circadian Clock genes Per2 and clock regulate steroid production, cell proliferation, and luteinizing hormone receptor transcription in ovarian granulosa cells

scientific article published on 27 July 2011

Comparison of bacterial endotoxin lipopolysaccharide concentrations in the blood, ovarian follicular fluid and uterine fluid: a clinical case of bovine metritis

scientific article

Comparison of cadherin and integrin localization in bovine cystic and healthy follicles

scientific article published on 3 December 2012

Differential expression of bone morphogenetic protein 4-6 (BMP-4, -5, and -6) and growth differentiation factor-9 (GDF-9) during ovarian development in neonatal pigs.

scientific article published in November 2004

Distribution of arteriolovenous vessels, capillaries and eNOS expression in the bovine corpus luteum during the estrous cycle: a possible implication of different sensitivity by luteal phase to PGF(2alpha) in the increase of luteal blood flow

scientific article published on 5 November 2009

Effect in dedicator of cytokinesis 6 (DOCK6) on steroid production in theca cells of follicular cysts.

scientific article

Effect of Lipopolysaccharide on Progesterone Production during Luteinization of Granulosa and Theca cells In Vitro

scientific article published on 05 January 2016

Effect of Single Nucleotide Polymorphisms of Toll-Like Receptor 4 (TLR 4) on Reproductive Performance and Immune Function in Dairy Cows

scientific article published on 16 January 2017

Effect of VEGF (vascular endothelial growth factor) on expression of IL-8 (interleukin-8), IL-1beta and their receptors in bovine theca cells

scientific article

Effect of direct ovarian injection of vascular endothelial growth factor gene fragments on follicular development in immature female rats

scientific article published in November 2007

Effect of lipopolysaccharide on developmental competence of oocytes

scientific article published on 10 April 2017

Effect of local neutralization of basic fibroblast growth factor or vascular endothelial growth factor by a specific antibody on the development of the corpus luteum in the cow.

scientific article published in September 2008

Effect of suckling on the reproductive performance and metabolic status of obese Japanese black cattle during the early postpartum period

scientific article published on 13 November 2007

Effects of interleukin-8 on estradiol and progesterone production by bovine granulosa cells from large follicles and progesterone production by luteinizing granulosa cells in culture

scientific article published on 29 November 2011

Emerging roles of immune cells in luteal angiogenesis

scientific article published on January 2013

Endothelin-1 downregulates sperm phagocytosis by neutrophils in vitro: A physiological implication in bovine oviduct immunity

scientific article published on 18 January 2016

Evidence that polymorphonuclear neutrophils infiltrate into the developing corpus luteum and promote angiogenesis with interleukin-8 in the cow.

scientific article

Evidence that the dominant follicle of the first wave is more active than that of the second wave in terms of its growth rate, blood flow supply and steroidogenic capacity in cows

scientific article published on 21 January 2014

Expression and glycosylation with polylactosamine of CD44 antigen on macrophages during follicular atresia in pig ovaries

scientific article published on 23 November 2005

Expression and localization of apelin and its receptor APJ in the bovine corpus luteum during the estrous cycle and prostaglandin F2alpha-induced luteolysis

scientific article published in April 2008

Expression of Pin1, a peptidyl-prolyl isomerase, in the ovaries of eCG/hCG-treated immature female mice.

scientific article published on 28 December 2005

Expression of fibroblast growth factor 1 (FGF1) and FGF7 in mature follicles during the periovulatory period after GnRH in the cow

scientific article published on 16 January 2006

Expression of mRNA for cell adhesion molecules in the bovine corpus luteum during the estrous cycle and PGF2alpha-induced luteolysis

scientific article published on 04 September 2007

Follicle-stimulating hormone (FSH) stimulates the expression of Pin1, a peptidyl-prolyl isomerase, in the bovine granulosa cells.

scientific article

Follicular microvasculature and angiogenic factors in the ovaries of domestic animals

scientific article published on June 2003

Gene injections of vascular endothelial growth factor and growth differentiation factor-9 stimulate ovarian follicular development in immature female rats

scientific article published in October 2007

Heat stress diminishes gonadotropin receptor expression and enhances susceptibility to apoptosis of rat granulosa cells

scientific article published in April 2005

Histone H3 acetylation of StAR and decrease in DAX-1 is involved in the luteinization of bovine granulosa cells during in vitro culture

scientific article published on 15 March 2009

Impact of angiogenic and innate immune systems on the corpus luteum function during its formation and maintenance in ruminants

scientific article published on 12 October 2013

Impact of metritis on the generation of reactive oxygen species by circulating phagocytes and plasma lipopolysaccharide concentration in peripartum dairy cows

scientific article published on 16 June 2016

In vivo evidence that local cortisol production increases in the preovulatory follicle of the cow.

scientific article published on 10 June 2005

Increased ovarian follicular angiogenesis and dynamic changes of follicular vascular plexuses induced by equine chorionic gonadotropin in the gilt

scientific article published on 24 April 2004

Induction of follicular development by direct single injection of vascular endothelial growth factor gene fragments into the ovary of miniature gilts

scientific article

Interleukin-8 stimulates progesterone production via the MEK pathway in ovarian theca cells

scientific article

Involvement of Ad4BP/SF-1, DAX-1, and COUP-TFII transcription factor on steroid production and luteinization in ovarian theca cells

scientific article published on 13 April 2008

Involvement of insulin and growth hormone (GH) during follicular development in the bovine ovary.

scientific article published on 18 April 2007

Involvement of lipopolysaccharide in ovarian cystic follicles in dairy cow: Expressions of LPS receptors and steroidogenesis-related genes in follicular cells of cystic follicles

scientific article published on 22 May 2018

Involvement of the luteinizing hormone surge in the regulation of ovary and oviduct clock gene expression in mice

scientific article published on 19 June 2018

Lipopolysaccharide (LPS) inhibits steroid production in theca cells of bovine follicles in vitro: distinct effect of LPS on theca cell function in pre- and post-selection follicles

scientific article

Lipopolysaccharide in ovarian follicular fluid influences the steroid production in large follicles of dairy cows

scientific article published on 22 November 2013

Long-term impact of puerperal metritis on the profiles of peripheral blood leukocytes in peripartum dairy cows

scientific article published on 21 September 2015

Luteinizing hormone (LH) regulates production of androstenedione and progesterone via control of histone acetylation of StAR and CYP17 promoters in ovarian theca cells

scientific article published on 2 December 2011

Manipulation of ovarian follicle development by injecting vascular endothelial growth factor (VEGF) gene.

scientific article

Messenger ribonucleic acid expressions of hepatocyte growth factor, angiopoietins and their receptors during follicular development in gilts

scientific article published in June 2003

Molecular cloning of porcine growth differentiation factor 9 (GDF-9) cDNA and its role in early folliculogenesis: direct ovarian injection of GDF-9 gene fragments promotes early folliculogenesis

scientific article published on November 2004

Nutritional factors that regulate ovulation of the dominant follicle during the first follicular wave postpartum in high-producing dairy cows

scientific article published on January 2012

Positive association, in local release, of luteal oxytocin with endothelin 1 and prostaglandin F2alpha during spontaneous luteolysis in the cow: a possible intermediatory role for luteolytic cascade within the corpus luteum

scientific article

Possible involvement of IFNT in lymphangiogenesis in the corpus luteum during the maternal recognition period in the cow.

scientific article published on 20 September 2011

Progesterone induces the expression of vascular endothelial growth factor (VEGF) 120 and Flk-1, its receptor, in bovine granulosa cells

scientific article published on 24 November 2006

Prostaglandin F2alpha differentially affects mRNA expression relating to angiogenesis, vasoactivation and prostaglandins in the early and mid corpus luteum in the cow.

scientific article published on 19 May 2010

Prostaglandin F2alpha increases endothelial nitric oxide synthase in the periphery of the bovine corpus luteum: the possible regulation of blood flow at an early stage of luteolysis

scientific article

Recent patents of TGF-beta family and VEGF associated with ovarian follicular development in mammals

scientific article published on January 2007

Regulation of innate immune function in bovine oviduct epithelial cells in culture: the homeostatic role of epithelial cells in balancing Th1/Th2 response

scientific article published on 21 June 2013

Relationship between metabolic hormones and ovulation of dominant follicle during the first follicular wave post-partum in high-producing dairy cows

scientific article published on 01 January 2007

Relationship between the degree of insulin resistance during late gestation and postpartum performance in dairy cows and factors that affect growth and metabolic status of their calves

scientific article published on 15 January 2016

Relationships Between the First Ovulation Postpartum and Polymorphism in Genes Relating to Function of Immunity, Metabolism and Reproduction in High-producing Dairy Cows ⬇️

scientific article published on 06 November 2010

Role of the hyaluronan receptor CD44 during porcine oocyte maturation.

scientific article published on 30 November 2006

Sperm Binding to Oviduct Epithelial Cells Enhances TGFB1 and IL10 Expressions in Epithelial Cells as Well as Neutrophils In Vitro: Prostaglandin E2 As a Main Regulator of Anti-Inflammatory Response in the Bovine Oviduct

scientific article

The absence of corpus luteum formation alters the endocrine profile and affects follicular development during the first follicular wave in cattle

scientific article

The differential pathways of bone morphogenetic protein (BMP)-4 and -7 in the suppression of the bovine granulosa cell apoptosis

scientific article published on 16 December 2008

The effect of single nucleotide polymorphisms in the tumor necrosis factor-α gene on reproductive performance and immune function in dairy cattle

scientific article

Upregulation of interferon-stimulated genes and interleukin-10 in peripheral blood immune cells during early pregnancy in dairy cows

scientific article published on 4 November 2011

Vascular endothelial growth factor (VEGF) suppresses ovarian granulosa cell apoptosis in vitro

scientific article published on 24 September 2007

Zearalenone (ZEN) disrupts the anti-inflammatory response of bovine oviductal epithelial cells to sperm in vitro

scientific article published on 28 September 2017

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