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List of works by Yuan-Tsong Chen

A common SCN5A polymorphism attenuates a severe cardiac phenotype caused by a nonsense SCN5A mutation in a Chinese family with an inherited cardiac conduction defect

scientific article published on 17 May 2006

A comparison of major histocompatibility complex SNPs in Han Chinese residing in Taiwan and Caucasians

scientific article published on 17 March 2006

A genome-wide association study identifies a novel susceptibility locus for the immunogenicity of polyethylene glycol

scientific article published on 12 September 2017

A genome-wide association study identifies susceptibility variants for type 2 diabetes in Han Chinese

scientific journal article

A genome-wide association study reveals a quantitative trait locus of adiponectin on CDH13 that predicts cardiometabolic outcomes

scientific article

A genome-wide survey of copy number variations in Han Chinese residing in Taiwan

scientific article published on 25 June 2009

A large kindred of early-onset osteoarthritis of the knee and hip: excluding the link to COL2A1 gene

scientific article published on 17 February 2009

A large-scale survey of genetic copy number variations among Han Chinese residing in Taiwan

scientific article

A new analysis tool for individual-level allele frequency for genomic studies

scientific article

A new nucleic acid–based agent inhibits cytotoxic T lymphocyte–mediated immune disorders ⬇️

scientific article published on June 19, 2013

A novel functional VKORC1 promoter polymorphism is associated with inter-individual and inter-ethnic differences in warfarin sensitivity.

scientific article

A prospective study of HLA*B-5801 genotyping in preventing allopurinol- induced severe cutaneous adverse reactions

scientific article

A recent update of pharmacogenomics in drug-induced severe skin reactions

scientific article

AAV vector-mediated reversal of hypoglycemia in canine and murine glycogen storage disease type Ia.

scientific article published on 11 March 2008

Alglucosidase alfa enzyme replacement therapy as a therapeutic approach for glycogen storage disease type III.

scientific article published on 27 December 2012

Alternative Splicing in Acad8 Resulting a Mitochondrial Defect and Progressive Hepatic Steatosis in Mice ⬇️

scientific article published on 01 July 2011

An integrated analysis tool for analyzing hybridization intensities and genotypes using new-generation population-optimized human arrays

scientific article

Antimicrobial Properties of an Immunomodulator - 15 kDa Human Granulysin

scientific article

Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels

scientific article

Association of circadian genes with diurnal blood pressure changes and non-dipper essential hypertension: a genetic association with young-onset hypertension

scientific article

Carbamazepine-Induced Toxic Effects and HLA-B*1502 Screening in Taiwan ⬇️

scientific article published on March 24, 2011

Chromosomal and genetic alterations in human hepatocellular adenomas associated with type Ia glycogen storage disease.

scientific article

Common risk allele in aromatic antiepileptic-drug induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Han Chinese

scientific article

Comparison of maltose and acarbose as inhibitors of maltase-glucoamylase activity in assaying acid alpha-glucosidase activity in dried blood spots for the diagnosis of infantile Pompe disease

scientific article published on 01 May 2006

Correlations between the enantio- and regio-selective metabolisms of warfarin

scientific article published on 20 December 2016

Cyclic Alopecia and Abnormal Epidermal Cornification in Zdhhc13-Deficient Mice Reveal the Importance of Palmitoylation in Hair and Skin Differentiation

scientific article published on 29 June 2015

De novo MECP2 duplication derived from paternal germ line result in dysmorphism and developmental delay

scientific article published on 12 October 2013

Determinants of the over-anticoagulation response during warfarin initiation therapy in Asian patients based on population pharmacokinetic-pharmacodynamic analyses

scientific article

Direct interaction between HLA-B and carbamazepine activates T cells in patients with Stevens-Johnson syndrome.

scientific article published on 8 February 2012

ENU mutagenesis identifies mice with cardiac fibrosis and hepatic steatosis caused by a mutation in the mitochondrial trifunctional protein beta-subunit

scientific journal article

ENU mutagenesis identifies mice with mitochondrial branched-chain aminotransferase deficiency resembling human maple syrup urine disease

scientific journal article

FASTSNP: an always up-to-date and extendable service for SNP function analysis and prioritization.

scientific article

Filamin B Loss-of-Function Mutation in Dimerization Domain Causes Autosomal-Recessive Spondylocarpotarsal Synostosis Syndrome with Rib Anomalies

scientific article published in February 2017

Functional analysis of novel SNPs and mutations in human and mouse genomes

scientific article

Garlic accelerates red blood cell turnover and splenic erythropoietic gene expression in mice: evidence for erythropoietin-independent erythropoiesis

scientific article

Genetic determinants of warfarin dosing in the Han-Chinese population

scientific article published in December 2009

Genetic polymorphisms of metabolic enzymes and the pharmacokinetics of indapamide in Taiwanese subjects

scientific article published on 20 December 2013

Genetic predisposition of life-threatening antiepileptic-induced skin reactions.

scientific article published on January 2010

Genetic susceptibility to carbamazepine-induced cutaneous adverse drug reactions.

scientific article

GenoWatch: a disease gene mining browser for association study

scientific article published on 25 April 2008

Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis

scientific article published on 19 December 2016

Genome-wide analysis of copy number variations identifies PARK2 as a candidate gene for autism spectrum disorder

scientific article published on April 2016

Genome-wide association studies in East Asians identify new loci for waist-hip ratio and waist circumference

scientific article published on 20 January 2016

Genome-wide association study identifies novel susceptibility loci for migraine in Han Chinese resided in Taiwan

scientific article

Genome-wide association study in NSAID-induced acute urticaria/angioedema in Spanish and Han Chinese populations

scientific article published in November 2013

Genome-wide association study of treatment refractory schizophrenia in Han Chinese

scientific journal article

Genome-wide association study of young-onset hypertension in the Han Chinese population of Taiwan

scientific article

Genome-wide expression profiles of subchondral bone in osteoarthritis

scientific article published on January 2013

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

scientific article

Genome-wide transcriptome analysis to further understand neutrophil activation and lncRNA transcript profiles in Kawasaki disease

scientific article published in Scientific Reports

Glucose tetrasaccharide as a biomarker for monitoring the therapeutic response to enzyme replacement therapy for Pompe disease

scientific article published in August 2005

Glycogen storage disease type IV: novel mutations and molecular characterization of a heterogeneous disorder

scientific article published on 8 January 2010

Glycogen-branching enzyme deficiency leads to abnormal cardiac development: novel insights into glycogen storage disease IV.

scientific article published on 12 November 2010

Granulysin is a key mediator for disseminated keratinocyte death in Stevens-Johnson syndrome and toxic epidermal necrolysis

article

HLA-B*1502-bound peptides: implications for the pathogenesis of carbamazepine-induced Stevens-Johnson syndrome.

scientific article

HLA-B*5801 allele as a genetic marker for severe cutaneous adverse reactions caused by allopurinol

scientific article

Han Chinese cell and genome bank in Taiwan: purpose, design and ethical considerations

article

Homozygosity Mapping and Whole-Genome Sequencing Links a Missense Mutation in POMGNT1 to Autosomal Recessive Retinitis Pigmentosa

scientific journal article

Human leukocyte antigens and drug hypersensitivity

scientific article (publication date: August 2007)

Identification of PTCSC3 as a Novel Locus for Large-Vessel Ischemic Stroke: A Genome-Wide Association Study

scientific article published on 29 March 2016

Identification of differentially expressed microRNAs in human hepatocellular adenoma associated with type I glycogen storage disease: a potential utility as biomarkers

scientific article published on 16 October 2013

Identification of functional single nucleotide polymorphisms in the branchpoint site

scientific article published on 9 November 2017

Identification of novel susceptibility Loci for kawasaki disease in a Han chinese population by a genome-wide association study

scientific journal article

Identification of susceptibility gene associated with female primary Sjögren's syndrome in Han Chinese by genome-wide association study

scientific article published on 8 August 2016

Inter-Individual Differences in Baseline Coagulation Activities and Their Implications for International Normalized Ratio Control During Warfarin Initiation Therapy ⬇️

scientific article published on December 1, 2012

Intragenic microdeletion of RUNX2 is a novel mechanism for cleidocranial dysplasia

scientific article published on January 2008

Knock-in human FGFR3 achondroplasia mutation as a mouse model for human skeletal dysplasia

scientific article published on 23 February 2017

Long contiguous stretches of homozygosity in the human genome

scientific article published on 01 November 2006

Loss of GPNMB Causes Autosomal-Recessive Amyloidosis Cutis Dyschromica in Humans

scientific article published on 9 January 2018

MPDA: microarray pooled DNA analyzer

scientific article

Mapping human genetic diversity in Asia

scientific article

Measurement of Pre-Existing IgG and IgM Antibodies against Polyethylene Glycol in Healthy Individuals

scientific article published on 11 October 2016

Medical genetics: a marker for Stevens-Johnson syndrome

scientific article

Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations

scientific article published on 15 July 2012

Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians

scientific article

Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians

scientific article

Mice with alopecia, osteoporosis, and systemic amyloidosis due to mutation in Zdhhc13, a gene coding for palmitoyl acyltransferase

scientific article

Mitochondrial GLUT10 facilitates dehydroascorbic acid import and protects cells against oxidative stress: mechanistic insight into arterial tortuosity syndrome

scientific article

Molecular profile and copy number analysis of sporadic colorectal cancer in Taiwan

scientific article

Mouse model of glycogen storage disease type III.

scientific article published on 18 February 2014

Mutations in the SLC2A10 gene cause arterial abnormalities in mice

scientific article published on 21 November 2008

Novel DNA sequence variations of cytochrome P450 genes in the Han Chinese population

scientific article

Novel susceptibility gene for nonfamilial hypokalemic periodic paralysis

scientific article published on 02 March 2016

Outer membrane protein I of Pseudomonas aeruginosa is a target of cationic antimicrobial peptide/protein

scientific article

Over-expression of AURKA, SKA3 and DSN1 contributes to colorectal adenoma to carcinoma progression

scientific article published on 13 June 2016

Palmitoyl acyltransferase, Zdhhc13, facilitates bone mass acquisition by regulating postnatal epiphyseal development and endochondral ossification: a mouse model

scientific article

Pharmacogenetic dosing of warfarin in the Han-Chinese population: a randomized trial

scientific article published on 23 January 2017

Pharmacogenetics of toxic epidermal necrolysis.

scientific article published on September 2010

Pharmacogenomics for personalized pain medicine

scientific article

Pharmacogenomics of adverse drug reactions: implementing personalized medicine

scientific article published on 19 August 2012

Population structure of Han Chinese in the modern Taiwanese population based on 10,000 participants in the Taiwan Biobank project

scientific article published on 18 October 2016

Predicting HLA genotypes using unphased and flanking single-nucleotide polymorphisms in Han Chinese population

scientific article published on 29 January 2014

PrimerZ: streamlined primer design for promoters, exons and human SNPs

scientific article published on 30 May 2007

Protein Palmitoylation by ZDHHC13 Protects Skin against Microbial-Driven Dermatitis

scientific article published on 22 December 2016

Replication and meta-analysis of GWAS identified susceptibility loci in Kawasaki disease confirm the importance of B lymphoid tyrosine kinase (BLK) in disease susceptibility

scientific article

Replication of genome-wide association signals of type 2 diabetes in Han Chinese in a prospective cohort

scientific article published in March 2012

SAQC: SNP array quality control

scientific article

SLC2A10 genetic polymorphism predicts development of peripheral arterial disease in patients with type 2 diabetes. SLC2A10 and PAD in type 2 diabetes

scientific article

Shared and restricted T-cell receptor use is crucial for carbamazepine-induced Stevens-Johnson syndrome

scientific article published on 14 September 2011

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

scientific article

Two new susceptibility loci for Kawasaki disease identified through genome-wide association analysis

scientific article

Type II collagen gene variants and inherited osteonecrosis of the femoral head

scientific article published in June 2005

Use of HLA-B*58:01 genotyping to prevent allopurinol induced severe cutaneous adverse reactions in Taiwan: national prospective cohort study

scientific article

Use of the Biopharmaceutics Drug Disposition Classification System (BDDCS) to Help Predict the Occurrence of Idiosyncratic Cutaneous Adverse Drug Reactions Associated with Antiepileptic Drug Usage

scientific article published on 7 March 2016

VKORC1 haplotypes in five East-Asian populations and Indians

scientific article

Variant GADL1 and response to lithium therapy in bipolar I disorder

scientific article published on 25 December 2013

VarioWatch: providing large-scale and comprehensive annotations on human genomic variants in the next generation sequencing era ⬇️

scientific article published on May 22, 2012

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