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List of works by Luke A Gilbert

A Bounty of New Challenging Targets in Oncology for Chemical Discovery

scientific article published on 25 July 2019

A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response

scientific article

A pan-CRISPR analysis of mammalian cell specificity identifies ultra-compact sgRNA subsets for genome-scale experiments

scientific article published on 02 February 2022

A senescence secretory switch mediated by PI3K/AKT/mTOR activation controls chemoprotective endothelial secretory responses

scientific article published on 26 August 2016

An integrated functional and clinical genomics approach reveals genes driving aggressive metastatic prostate cancer

scientific article published on 29 July 2021

Bcl-2 Family Genetic Profiling Reveals Microenvironment-Specific Determinants of Chemotherapeutic Response ⬇️

scientific article published on July 22, 2011

CRISPR interference (CRISPRi) for sequence-specific control of gene expression

scientific article

Cellular response to small molecules that selectively stall protein synthesis by the ribosome

scientific article published on 15 March 2019

Exploration of Benzothiazole Rhodacyanines as Allosteric Inhibitors of Protein-Protein Interactions with Heat Shock Protein 70 (Hsp70)

scientific article published on 13 July 2018

Exploring genetic interaction manifolds constructed from rich single-cell phenotypes

scientific article published on 08 August 2019

Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer

KRASG12C inhibition produces a driver-limited state revealing collateral dependencies

scientific article published on 28 May 2019

Mapping cancer genetics at single-cell resolution

scientific article published on 01 August 2020

Parallel shRNA and CRISPR-Cas9 screens enable antiviral drug target identification

scientific article

The DNA methylation landscape of advanced prostate cancer

scientific article published on 13 July 2020

The Promise and Challenge of In Vivo Delivery for Genome Therapeutics.

scientific article published on 11 October 2017

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