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List of works by Shigeru Morinobu

A case of myclonus, resembling epileptic seizure, induced by short-term sulpiride treatment

scientific article published on 01 January 2002

A case of venous thromboembolism probably associated with hyperprolactinemia after the addition of olanzapine to typical antipsychotics.

scientific article published in November 2004

Alterations in the hippocampal glycinergic system in an animal model of posttraumatic stress disorder

scientific article published on 27 April 2010

Antidepressant drugs and cytokines in mood disorders

scientific article

Antidepressant-like effect of sodium butyrate (HDAC inhibitor) and its molecular mechanism of action in the rat hippocampus ⬇️

scientific article published on August 3, 2011

Antidepressive effect of sodium butyrate and its effect on gene expression in rat hippocampus

scientific article published on 01 April 2011

Association of Typical versus Atypical Antipsychotics with Symptoms and Quality of Life in Schizophrenia ⬇️

scientific article published on May 16, 2012

Asymmetric alternation of the hemodynamic response at the prefrontal cortex in patients with schizophrenia during electroconvulsive therapy: A near-infrared spectroscopy study ⬇️

scientific article published on June 29, 2011

Blood diagnostic biomarkers for major depressive disorder using multiplex DNA methylation profiles: discovery and validation

scientific article

Chemogenetic activation of the mPFC alleviates impaired fear memory extinction in an animal model of PTSD

scientific article published on 04 September 2020

Combined brain-derived neurotrophic factor with extinction training alleviate impaired fear extinction in an animal model of post-traumatic stress disorder

scientific article published on 09 October 2018

Cortical activation changes and sub-threshold affective symptoms are associated with social functioning in a non-clinical population: A multi-channel near-infrared spectroscopy study

scientific article published on 4 January 2016

DNA methylation profiles of the brain-derived neurotrophic factor (BDNF) gene as a potent diagnostic biomarker in major depression

scientific article

Decreased levels of ghrelin, cortisol, and fasting blood sugar, but not n-octanoylated ghrelin, in Japanese schizophrenic inpatients treated with olanzapine

scientific article published on 22 May 2008

Decreased levels of whole blood glial cell line-derived neurotrophic factor (GDNF) in remitted patients with mood disorders

scientific article published on 28 September 2005

EPRI to estimate the in vivo intracerebral reducing ability in adolescent rats subjected to neonatal isolation

scientific article published in May 2006

Effect of neonatal isolation on the noradrenergic transduction system in the rat hippocampal slice

scientific article published in December 2004

Effect of paroxetine on enhanced contextual fear induced by single prolonged stress in rats

scientific article published on 10 October 2006

Effect of risperidone on sleep in schizophrenia: a comparison with haloperidol

scientific article

Effect of switching to atypical antipsychotics on memory in patients with chronic schizophrenia

scientific article

Effects of changing from typical to atypical antipsychotic drugs on subjective sleep quality in patients with schizophrenia in a Japanese population.

scientific article published in November 2004

Effects of single prolonged stress and D-cycloserine on contextual fear extinction and hippocampal NMDA receptor expression in a rat model of PTSD.

scientific article published on 24 October 2007

Electroconvulsive seizure induces thrombospondin-1 in the adult rat hippocampus

scientific article published on 11 October 2013

Electroconvulsive seizure, but not imipramine, rapidly up-regulates pro-BDNF and t-PA, leading to mature BDNF production, in the rat hippocampus ⬇️

scientific article published on February 6, 2012

Enhanced hippocampal BDNF/TrkB signaling in response to fear conditioning in an animal model of posttraumatic stress disorder ⬇️

scientific article published on September 21, 2010

Epigenetic mechanism of depression

scientific article published on January 1, 2010

Epigenetic regulation of BDNF gene in response to stress

scientific article published on 13 December 2010

Histone Acetylation in the Hippocampus and Fear Extinction ⬇️

scientific article published on July 1, 2012

Imipramine, but not lithium, induces the serine/threonine phosphatase activity of calcineurin without affecting its mRNA expression in the rat brain

scientific article

Importance of early environment in the development of post-traumatic stress disorder-like behaviors

scientific article published on 24 July 2006

Importance of early lighting conditions in maternal care by dam as well as anxiety and memory later in life of offspring

scientific article

Influence of aging on the improvement of subjective sleep quality by atypical antipsychotic drugs in patients with schizophrenia: comparison of middle-aged and older adults

scientific article published in May 2005

Influence of immobilization stress on the expression and phosphatase activity of protein phosphatase 2A in the rat brain

scientific article published in November 2003

Influence of immobilization stress on the levels of CaMKII and phospho-CaMKII in the rat hippocampus

scientific article published on 26 April 2004

Influence of stress on the activation of CaMKII in the brain

scientific article published in August 2006

Maternal postpartum learned helplessness (LH) affects maternal care by dams and responses to the LH test in adolescent offspring

scientific article

Neonatal isolation changes the expression of IGF-IR and IGFBP-2 in the hippocampus in response to adulthood restraint stress

scientific article published on 19 July 2006

Novel therapeutic approach for the treatment of post-traumatic stress disorder (PTSD): facilitating fear extinction

scientific article published on August 1, 2012

Obsessive-compulsive disorder with non-24-hour sleep-wake syndrome

scientific article published in September 2002

PS257. The effects of brain-derived neurotrophic factor (BDNF) micro-infusion on the impaired fear extinction of the animal model of PTSD.

scientific article

Predictors of quality of life in inpatients with schizophrenia ⬇️

scientific article published on February 26, 2012

Prior neonatal isolation reduces induction of NGF mRNA and decreases GDNF mRNA in the hippocampus of juvenile and adult rodents subjected to immobilization stress

scientific article published on April 2008

Resting state low-frequency fluctuations in prefrontal cortex reflect degrees of harm avoidance and novelty seeking: an exploratory NIRS study

scientific article published on 17 December 2013

Single immobilization stress differentially alters the expression profile of transcripts of the brain-derived neurotrophic factor (BDNF) gene and histone acetylation at its promoters in the rat hippocampus

scientific article published on 11 June 2008

Single prolonged stress increases contextual freezing and the expression of glycine transporter 1 and vesicle-associated membrane protein 2 mRNA in the hippocampus of rats

scientific article

Single prolonged stress: toward an animal model of posttraumatic stress disorder

scientific article published on January 2009

Structural variation in the glycogen synthase kinase 3β and brain-derived neurotrophic factor genes in Japanese patients with bipolar disorders

scientific article published on 26 November 2019

The Degree of Early Life Stress Predicts Decreased Medial Prefrontal Activations and the Shift from Internally to Externally Guided Decision Making: An Exploratory NIRS Study during Resting State and Self-Oriented Task

scientific article

The effects of antidepressant drug treatments on activator protein-1 binding activity in the rat brain

scientific article published in February 2002

The influence of aging on the methylation status of brain-derived neurotrophic factor gene in blood

scientific article published on 28 June 2018

The potential of SLC6A4 gene methylation analysis for the diagnosis and treatment of major depression

scientific article published on 21 February 2014

The potential use of histone deacetylase inhibitors in the treatment of depression

scientific article

The role of glucocorticoid receptors in the induction and prevention of hippocampal abnormalities in an animal model of posttraumatic stress disorder

scientific article published on 24 April 2020

The tolerability of oral-loaded valproate after remission of acute mania in Japanese patients with bipolar disorder

scientific article published on January 2007

Visual emotional stimuli modulation of auditory sensory gating studied by magnetic P50 suppression

scientific article published on 12 November 2004

Vorinostat ameliorates impaired fear extinction possibly via the hippocampal NMDA-CaMKII pathway in an animal model of posttraumatic stress disorder ⬇️

scientific article published on April 13, 2013

Vorinostat, a histone deacetylase inhibitor, facilitates fear extinction and enhances expression of the hippocampal NR2B-containing NMDA receptor gene ⬇️

scientific article published on February 25, 2012

beta-estradiol, dehydroepiandrosterone, and dehydroepiandrosterone sulfate protect against N-methyl-D-aspartate-induced neurotoxicity in rat hippocampal neurons by different mechanisms

scientific article

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