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List of works by Ernesto Fattorusso

1H-NMR studies of the interactions of two distamycin analogues with the dodecamer d(CGCGAATTCGCG)2

scientific article published in 1992

A 4-decade-long (and still ongoing) hunt for palytoxins chemical architecture

scientific article published on 29 September 2010

A New Iodinated Metabolite and a New Alkyl Sulfate from the Senegalese SpongePtilocaulisspiculifer

A biosynthetically significant new bacteriohopanoid present in large amounts in the Caribbean sponge Plakortis simplex

A new aspect of the reactivity of sodium dithionite provides a facile route to 2-deoxy-α-glycosides

A new class of antimalarial dioxanes obtained through a simple two-step synthetic approach: rational design and structure-activity relationship studies

scientific article

A new cytotoxic polychlorinated sulfolipid from contaminated Adriatic mussels

A prenylbisabolane with NF-kappaB inhibiting properties from Cascarilla (Croton eluteria).

scientific article published in July 2005

ADP-ribosyl cyclases generate two unusual adenine homodinucleotides with cytotoxic activity on mammalian cells

scientific article

Activity against Plasmodium falciparum of cycloperoxide compounds obtained from the sponge Plakortis simplex.

scientific article published on December 2002

Acyclic polyhalogenated monoterpenes from four marine hydroids

scientific article published in 1984

Amino acids, sugars and sterols of some Mediterranean brown algae

scientific article published in 1976

Amphiceramide A and B, Novel Glycosphingolipids from the Marine SpongeAmphimedon compressa

An unusual ether glycolipid from the Senegalese sponge Trikentrion loeve Carter

Antimalarial Polyketide Cycloperoxides from the Marine SpongePlakortis simplex

Antimalarials based on the dioxane scaffold of plakortin. A concise synthesis and SAR studies

scientific article published on 11 November 2010

Antiplasmodial triterpenoids from the fruits of neem, Azadirachta indica.

scientific article published on August 2010

Antispasmodic saponins from bulbs of red onion, Allium cepa L. var. Tropea

scientific article published in February 2005

Antitumor effects of two novel naturally occurring terpene quinones isolated from the Mediterranean ascidian Aplidium conicum.

scientific article

Aplidiasterols A and B, two new cytotoxic 9,11-secosterols from the Mediterranean ascidian Aplidium conicum

scientific article published on October 2003

Aplisulfamines, New Sulfoxide-Containing Metabolites from an Aplidium Tunicate: Absolute Stereochemistry at Chiral Sulfur and Carbon Atoms Assigned Through an Original Combination of Spectroscopic and Computational Methods

scientific article published on January 4, 2012

Artarborol, a nor-caryophyllane sesquiterpene alcohol from Artemisia arborescens. stereostructure assignment through concurrence of NMR data and computational analysis

scientific article

Assignment of the absolute stereochemistry of oxazinin-1: application of the 9-AMA shift-correlation method for β-chiral primary alcohols

Aurantoside J: a new tetramic acid glycoside from Theonella swinhoei. Insights into the antifungal potential of aurantosides

scientific article published on 20 December 2011

Biogeographic effects of the Gulf of Mexico red tide dinoflagellate Karenia brevis on Mediterranean copepods

scholarly article by Jefferson T. Turner et al published April 2012 in Harmful Algae

Bisnorsesquiterpenoids from Euphorbia resinifera Berg. and an Expeditious Procedure to Obtain Resiniferatoxin from Its Fresh Latex

Brominaed β-carbolines from the marine hydroid aglaophenia pluma linnaeus

Bromopyrrole alkaloids as lead compounds against protozoan parasites

scientific article

Caulerpenyne, an unusual sequiterpenoid from the green alga caulerpa prolifera

Cellular localisation of secondary metabolites isolated from the Caribbean sponge Plakortis simplex

scientific article published in 2007

Chapter 1 Recent Developments in Mediterranean Harmful Algal Events

Characterization of 27-hydroxy-13-desmethyl spirolide C and 27-oxo-13,19-didesmethyl spirolide C. Further insights into the complex Adriatic Alexandrium ostenfeldii toxin profile

scientific article published on 30 July 2010

ChemInform Abstract: Lobozoanthamine, a New Zoanthamine-Type Alkaloid from the Indonesian Soft Coral Lobophytum sp

ChemInform Abstract: Oxygenated Cembranoids of the Decaryiol Type from the Indonesian Soft Coral Lobophytum sp

ChemInform Abstract: Sinularioside, a Triacetylated Glycolipid from the Indonesian Soft Coral Sinularia sp., Is an Inhibitor of NO Release

ChemInform Abstract: Xenimanadins A-D, a Family of Xenicane Diterpenoids from the Indonesian Soft Coral Xenia sp

Chemical composition of shallot (Allium ascalonicum Hort.).

scientific article published in September 2002

Chemical diversity of bioactive marine natural products: an illustrative case study

scientific article published in July 2004

Chemistry of Verongida sponges. VII bromocompounds from the caribbean sponge Aplysina archeri

Chloroscabrolides, chlorinated norcembranoids from the Indonesian soft coral Sinularia sp

Clavaminols A-F, novel cytotoxic 2-amino-3-alkanols from the ascidian Clavelina phlegraea.

scientific article

Clotrimazole scaffold as an innovative pharmacophore towards potent antimalarial agents: design, synthesis, and biological and structure-activity relationship studies

scientific article published on 16 February 2008

Cold stress defense in the freshwater sponge Lubomirskia baicalensis. Role of okadaic acid produced by symbiotic dinoflagellates

scientific article

Comparative growth and toxin profile of cultured Ostreopsis ovata from the Tyrrhenian and Adriatic Seas

scientific article published on 26 July 2009

Complex palytoxin-like profile of Ostreopsis ovata. Identification of four new ovatoxins by high-resolution liquid chromatography/mass spectrometry

scientific article published on September 2010

Complex toxin profile of Mytilus galloprovincialis from the Adriatic sea revealed by LC-MS.

scientific article published on 4 August 2009

Complex yessotoxins profile in Protoceratium reticulatum from north-western Adriatic sea revealed by LC–MS analysis

article

Conicamin, a novel histamine antagonist from the mediterranean tunicate Aplidium conicum

scientific article

Corrugoside, a new immunostimulatory alpha-galactoglycosphingolipid from the marine sponge Axinella corrugata

scientific article published on 4 November 2007

Coumarins from Opopanax chironium. New dihydrofuranocoumarins and differential induction of apoptosis by imperatorin and heraclenin.

scientific article published in April 2004

Cytotoxic Activity of Crude Extracts as well as of Pure Components from Jatropha Species, Plants Used Extensively in African Traditional Medicine

scientific article

Cytotoxic germacrane sesquiterpenes from the aerial parts of Santolina insularis

scientific article published on June 2005

Damicoside from Axinella damicornis: the influence of a glycosylated galactose 4-OH group on the immunostimulatory activity of alpha-galactoglycosphingolipids.

scientific article published in November 2005

Damipipecolin and damituricin, novel bioactive bromopyrrole alkaloids from the Mediterranean sponge Axinella damicornis

scientific article published on 07 June 2007

Dehydroconicasterol and aurantoic acid, a chlorinated polyene derivative, from the Indonesian sponge Theonella swinhoei.

scientific article published in December 2009

Design and synthesis of potent antimalarial agents based on clotrimazole scaffold: exploring an innovative pharmacophore

scientific article published on 31 January 2007

Design, synthesis, and structure-activity relationship studies of 4-quinolinyl- and 9-acrydinylhydrazones as potent antimalarial agents

scientific article published on 16 February 2008

Desulfohaplosamate, a new phosphate-containing steroid from Dasychalina sp., is a selective cannabinoid CB2 receptor ligand

scientific article published on 19 April 2011

Desulfoyessotoxins from Adriatic Mussels: A New Problem for Seafood Safety Control

scientific article published on 01 January 2007

Dictyol A and B, two novel diterpene alcohols from the brown alga Dictyota dichotoma

Dilphol, a new ten-membered-ring diterpene alcohol from the brown alga Dilophus ligulatus

Discovery and biological evaluation of the novel naturally occurring diterpene pepluanone as antiinflammatory agent

scientific article published on November 2005

Discovery of a new series of jatrophane and lathyrane diterpenes as potent and specific P-glycoprotein modulators

scientific article published on 28 March 2008

Diterpenoids from Cascarilla (Croton eluteria Bennet).

scientific article published in August 2002

Endoperoxide derivatives from marine organisms: 1,2-dioxanes of the plakortin family as novel antimalarial agents.

scientific article published on November 2006

Evaluation of the Antiproliferative Activity of Diterpene Isonitriles from the SpongePseudoaxinella flavain Apoptosis-Sensitive and Apoptosis-Resistant Cancer Cell Lines

scientific article published on 10 October 2011

First finding of Ostreopsis cf. ovata toxins in marine aerosols

scientific article published on 7 March 2014

Free protein amino acids of some Mediterranean Siphonales

scientific article published in 1984

Full relative stereochemistry assignment and conformational analysis of 13,19-didesmethyl spirolide C via NMR- and molecular modeling-based techniques. A step towards understanding spirolide’s mechanism of action

scientific article published on 16 July 2009

Further Investigation of the Mediterranean Sponge Axinella polypoides: Isolation of a New Cyclonucleoside and a New Betaine

scientific article published on November 9, 2012

Further optimization of plakortin pharmacophore: structurally simple 4-oxymethyl-1,2-dioxanes with promising antimalarial activity

scientific article published on 27 October 2013

Glycolipids from Sponges. 11.1Isocrasserides, Novel Glycolipids with a Five-Membered Cyclitol Widely Distributed in Marine Sponges

scientific article published on 01 June 2002

Glycolipids from Sponges. 20.(1)J-Coupling Analysis for Stereochemical Assignments in Furanosides: Structure Elucidation of Vesparioside B, a Glycosphingolipid from the Marine SpongeSpheciospongia vesparia

scientific article published on 24 July 2008

Glycolipids from Sponges. 6.1Plakoside A and B, Two Unique Prenylated Glycosphingolipids with Immunosuppressive Activity from the Marine SpongePlakortis simplex

scientific article published in 1997

Glycolipids from Sponges. Part 17.1Clathrosides and Isoclathrosides, Unique Glycolipids from the Caribbean SpongeAgelasclathrodes

scientific article published on 01 January 2006

Glycolipids from Sponges. Part 8: Plakopolyprenoside from the Marine Sponge Plakortis simplex. An Improved Procedure for Isolation of Glycolipids as Peracetyl Derivatives

Glycolipids from sponges. 13. Clarhamnoside, the first rhamnosylated alpha-galactosylceramide from Agelas clathrodes. Improving spectral strategies for glycoconjugate structure determination

scientific article published in February 2004

Glycolipids from sponges. IV. Immunomodulating glycosyl ceramides from the marine sponge agelas dispar

Glycolipids from sponges. Part 16.(1) discoside, a rare myo-inositol-containing glycolipid from the caribbean sponge Discodermia dissoluta

scientific article

Gonyaulax spinifera from the Adriatic sea: Toxin production and phylogenetic analysis

article

High Resolution LC-MSn Fragmentation Pattern of Palytoxin as Template to Gain New Insights into Ovatoxin-a Structure. The Key Role of Calcium in MS Behavior of Palytoxins

scientific article published on 22 February 2012

Hydrophilic interaction liquid chromatography/mass spectrometry for determination of domoic acid in Adriatic shellfish

scientific article published in January 2005

Immunomodulatory α-Galactoglycosphingolipids: Synthesis of 2'-Fluoro-2'-deoxy-α-galactosylceramide and an Evaluation of Its Immunostimulating Properties

Immunomodulatoryα-Galactoglycosphingolipids: Synthesis of a 2′-O-Methyl-α-Gal-GSL and Evaluation of Its Immunostimulating Capacity

Influence of temperature and salinity on Ostreopsis cf. ovata growth and evaluation of toxin content through HR LC-MS and biological assays

article by Laura Pezzolesi et al published 1 January 2012 in Water Research

Influence of temperature, salinity and nutrient limitation on yessotoxin production and release by the dinoflagellate Protoceratium reticulatum in batch-cultures

article

Insight into the mechanism of action of plakortins, simple 1,2-dioxane antimalarials

scientific article published on 16 December 2009

Investigation of the toxin profile of Greek mussels Mytilus galloprovincialis by liquid chromatography-mass spectrometry

scientific article published on 5 December 2005

Investigation of toxin profile of Mediterranean and Atlantic strains of Ostreopsis cf. siamensis (Dinophyceae) by liquid chromatography–high resolution mass spectrometry

Iodocionin, a cytotoxic iodinated metabolite from the Mediterranean ascidian Ciona edwardsii

scientific article published on 21 February 2010

Isolation and Structure Elucidation of New and Unusual Saxitoxin Analogues from Mussels

article

Isolation and structure elucidation of ovatoxin-a, the major toxin produced by Ostreopsis ovata

scientific article published on 11 January 2012

Isolation of new rotenoids from Boerhaavia diffusa and evaluation of their effect on intestinal motility

scientific article published on 01 October 2005

Jatrophane diterpenes as P-glycoprotein inhibitors. First insights of structure-activity relationships and discovery of a new, powerful lead

scientific article

Jatrophane diterpenes as modulators of multidrug resistance. Advances of structure-activity relationships and discovery of the potent lead pepluanin A.

scientific article published on February 2004

LC-MS of palytoxin and its analogues: State of the art and future perspectives

scientific article

Leucettamols, bifunctionalized marine sphingoids, act as modulators of TRPA1 and TRPM8 channels

scientific article published on 2 November 2012

Linear sesterterpenes from the Caribbean sponge Thorecta horridus with inflammatory activity

scientific article published in 1991

Lintenolides, new pentacyclic bioactive sesterterpenes from the caribbean sponge Cacospongia cf. linteiformis

Lobozoanthamine, a new zoanthamine-type alkaloid from the Indonesian soft coral Lobophytum sp

Manadoperoxides A-D from the Indonesian sponge Plakortis cfr. simplex. Further insights on the structure-activity relationships of simple 1,2-dioxane antimalarials

scientific article published in June 2010

Manadoperoxides, a new class of potent antitrypanosomal agents of marine origin

scientific article

Marine antimalarials

scientific article published on 23 April 2009

Mechanism of cytotoxicity of turbinamide in vitro.

scientific article published on September 2002

Minor diterpenoids from cascarilla (Croton eluteria Bennet) and evaluation of the cascarilla extract and cascarillin effects on gastric acid secretion

scientific article published in November 2003

Modified jatrophane diterpenes as modulators of multidrug resistance from Euphorbia dendroides L.

scientific article published on November 2003

Mumijo traditional medicine: fossil deposits from antarctica (chemical composition and beneficial bioactivity)

scientific article

New insights on cytological and metabolic features of Ostreopsis cf. ovata Fukuyo (Dinophyceae): a multidisciplinary approach

scientific article

New nitrogenous sesquiterpenes based on alloaromadendrane and epi-eudesmane skeletons from the marine sponge Axinellacannabina

Nitrogen and phosphorus limitation effects on cell growth, biovolume, and toxin production in Ostreopsis cf. ovata

article

Nonprenylated rotenoids, a new class of potent breast cancer resistance protein inhibitors

scientific article

Nor-sterols in Axinella proliferans, sponge from the Indian Ocean

scientific article published in 1996

Novel bioactive bromopyrrole alkaloids from the Mediterranean sponge Axinella verrucosa

scientific article published on 16 September 2005

Okadaic acid in mussels of Adriatic sea

Okadaic acid, an apoptogenic toxin for symbiotic/parasitic annelids in the demosponge Suberites domuncula

scientific article

Oreacerebrosides: Bioactive Cerebrosides with a Triunsaturated Sphingoid Base from the Sea StarOreaster reticulatus

Ostreopsis cf. ovata bloom in the northern Adriatic Sea during summer 2009: ecology, molecular characterization and toxin profile

scientific article published on 7 September 2011

Oxazinin-1, -2 and -3 − A Novel Toxic Compound and Its Analogues from the Digestive Glands of Mytilus galloprovincialis

article

Oxazinins from toxic mussels: isolation of a novel oxazinin and reassignment of the C-2 configuration of oxazinin-1 and -2 on the basis of synthetic models

article

Oxocrinol and crinitol, novel linear terpenoids from the brown alga Cystoseira crinita

Oxygenated cembranoids of the decaryiol type from the Indonesian soft coral Lobophytum sp

Palytoxin and an Ostreopsis toxin extract increase the levels of mRNAs encoding inflammation-related proteins in human macrophages via p38 MAPK and NF-κB

scientific article

Palytoxin in seafood by liquid chromatography tandem mass spectrometry: investigation of extraction efficiency and matrix effect

scientific article

Palytoxins: A still haunting Hawaiian curse

Paraliane and pepluane diterpenes as anti-inflammatory agents: first insights in structure-activity relationships

scientific article published on 25 May 2007

Partial characterization of glycosphingolipids of Agelas sponges in their peracetylated form by liquid secondary ionization mass spectrometry and high-performance liquid chromatography combined with direct electrospray ionization mass spectrometric d

scientific article published on 01 January 2004

Polyaxibetaine, an amino acid derivative from the marine sponge Axinella polypoides

scientific article published in April 2010

Polychlorinated Androstanes from the Burrowing Sponge Cliona nigricans

Polychlorinated Androstanes from the Burrowing SpongeCliona nigricans

scientific article published on 01 May 2004

Polyhydroxylated sterols from the Indonesian soft coral Sinularia sp. and their effect on farnesoid X-activated receptor.

scientific article

Polyoxygenated eudesmanes and trans-chrysanthemanes from the aerial parts of Santolina insularis

scientific article published in January 2004

Polysiphenol, a new brominated 9,10-dihydrophenanthrene from the senegalese red alga polysyphonia ferulacea

Potent antioxidant and genoprotective effects of boeravinone G, a rotenoid isolated from Boerhaavia diffusa

scientific article

Putative palytoxin and its new analogue, ovatoxin-a, in Ostreopsis ovata collected along the Ligurian coasts during the 2006 toxic outbreak

scientific article published on 7 November 2007

Saponins and flavonoids of Allium triquetrum

scientific article

Simplakidine A, a unique pyridinium alkaloid from the Caribbean sponge plakortis simplex

scientific article published on March 2003

Simplexidine, a 4-alkylpyridinium alkaloid from the Caribbean sponge Plakortis simplex

scientific article

Sinularioside, a triacetylated glycolipid from the Indonesian soft coral Sinularia sp., is an inhibitor of NO release

scientific article published on 8 March 2012

Sinulasulfoxide and sinulasulfone, sulfur-containing alkaloids from the Indonesian soft coral Sinularia sp

Skin lipid structure controls water permeability in snake molts

scientific article

Spasmolytic effects of nonprenylated rotenoid constituents of Boerhaavia diffusa roots

scientific article published in June 2006

Spirocurcasone, a diterpenoid with a novel carbon skeleton from Jatropha curcas

scientific article published on 9 December 2010

Spirolide toxin profile of Adriatic Alexandrium ostenfeldii cultures and structure elucidation of 27-hydroxy-13,19-didesmethyl spirolide C.

scientific article

Stereochemical Studies on Ovatoxin-a

scientific article published on 29 October 2012

Stereostructural Determination by a Synthetic and NMR-Based Approach of Three Oxazinins Isolated from Adriatic Mussels

Stereostructure and biological activity of 42-hydroxy-palytoxin: a new palytoxin analogue from Hawaiian Palythoa subspecies

scientific article published in November 2009

Stereostructure assignment of medium-sized rings through an NMR-computational combined approach. Application to the new germacranes ketopelenolides C and D.

scientific article

Structure and absolute stereochemistry of cyclolinteinone a novel monocarbocyclic sesterterpene from Cacospongia cf. linteiformis

Structure and stereochemistry of a new cytotoxic polychlorinated sulfolipid from Adriatic shellfish

scientific article published in November 2002

Structure of bromotetrasphaerol, a further irregular diterpene from the red alga

Structure-activity relationships for euphocharacins A-L, a new series of jatrophane diterpenes, as inhibitors of cancer cell P-glycoprotein.

scientific article published on July 2004

Structure−Activity Relationships of Yessotoxins in Cultured Cells

scientific article published on 01 September 2004

Synthesis of N1-arylidene-N2-quinolyl- and N2-acrydinylhydrazones as potent antimalarial agents active against CQ-resistant P. falciparum strains

scientific article published on 4 August 2006

Synthesis of structurally simplified analogues of aplidinone A, a pro-apoptotic marine thiazinoquinone.

scientific article

Tedanol: a potent anti-inflammatory ent-pimarane diterpene from the Caribbean Sponge Tedania ignis

scientific article published on 13 September 2009

Tedarenes A and B: Structural and Stereochemical Analysis of Two New Strained Cyclic Diarylheptanoids from the Marine Sponge Tedania ignis

scientific article published on 29 March 2012

Terpioside B, a difucosyl GSL from the marine sponge Terpios sp. is a potent inhibitor of NO release

scientific article published on 24 May 2010

Terpioside from the Marine SpongeTerpios sp., the First Glycosphingolipid Having anL-Fucofuranose Unit

The Detection and Identification of 42,43,44,45,46,47,55-Heptanor-41-oxoyessotoxin, a New Marine Toxin from Adriatic Shellfish, by Liquid Chromatography−Mass Spectrometry

scientific article published on 01 July 2002

The Genoa 2005 Outbreak. Determination of Putative Palytoxin in MediterraneanOstreopsisovataby a New Liquid Chromatography Tandem Mass Spectrometry Method

scientific article published on 01 September 2006

The Stereochemistry of Crasserides

The Wittig reaction with 2-deoxysugars: the role of triphenyl and trialkyltin halides

The interaction of heme with plakortin and a synthetic endoperoxide analogue: new insights into the heme-activated antimalarial mechanism

scientific article published on 06 April 2017

The molecular basis for the evolution of the metazoan bodyplan: extracellular matrix-mediated morphogenesis in marine demosponges

scientific article published in January 2003

Three New Brominated and Iodinated Tyrosine Derivatives from Iotrochota birotulata, a Non-Verongida Sponge

Three squalene derivatives from Caulerpa prolifera

Toxin levels and profiles in microalgae from the north-Western Adriatic Sea--15 years of studies on cultured species

scientific article published on 17 January 2012

Toxin profile of Alexandrium ostenfeldii (Dinophyceae) from the Northern Adriatic Sea revealed by liquid chromatography-mass spectrometry

scientific article published on 24 March 2006

Toxin-producing Ostreopsis cf. ovata are likely to bloom undetected along coastal areas

scientific article published on 4 May 2012

Toxins from Adriatic blue mussels. A decade of studies

article by Patrizia Ciminiello et al published 1 January 2003 in Pure and Applied Chemistry

Unique toxin profile of a Mediterranean Ostreopsis cf. ovata strain: HR LC-MS(n) characterization of ovatoxin-f, a new palytoxin congener.

scientific article

Vesparioside from the Marine SpongeSpheciospongia vesparia, the First Diglycosylceramide with a Pentose Sugar Residue

article by Valeria Costantino et al published January 2005 in European Journal of Organic Chemistry

Volatile mono- and sesquiterpeneoids from Kleinia pendula

Xenimanadins A–D, a family of xenicane diterpenoids from the Indonesian soft coral Xenia sp

Yessotoxin, a shellfish biotoxin, is a potent inducer of the permeability transition in isolated mitochondria and intact cells

scientific article published on June 2004

Zorrimidazolone, a Bioactive Alkaloid from the Non-Indigenous Mediterranean Stolidobranch Polyandrocarpa zorritensis

scientific article published on June 23, 2011