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List of works by Paul N Hopkins

25-Hydroxyvitamin D is associated with plasma renin activity and the pressor response to dietary sodium intake in Caucasians

scientific article

A clustering analysis of lipoprotein diameters in the metabolic syndrome

scientific article published on 19 December 2011

A comparative study of four independent methods to measure LDL particle concentration

scientific article published on 3 September 2015

A family-specific linkage analysis of blood lipid response to fenofibrate in the Genetics of Lipid Lowering Drug and Diet Network

scientific article

A genome scan for linkage with aortic root diameter in hypertensive African Americans and whites in the Hypertension Genetic Epidemiology Network (HyperGEN) study

scientific article published in May 2005

A genome scan for loci influencing anti-atherogenic serum bilirubin levels

scientific article published on 01 September 2002

A genome-wide association study of inflammatory biomarker changes in response to fenofibrate treatment in the Genetics of Lipid Lowering Drug and Diet Network

scientific article published on March 2012

A high intake of saturated fatty acids strengthens the association between the fat mass and obesity-associated gene and BMI.

scientific article published on 2 November 2011

A mutation in PCSK9 causing autosomal-dominant hypercholesterolemia in a Utah pedigree

scientific article

A prevalent caveolin-1 gene variant is associated with the metabolic syndrome in Caucasians and Hispanics

scientific article

A whole genome scan for pulse pressure/stroke volume ratio in African Americans: the HyperGEN study

scientific article

Abnormal Aldosterone Physiology and Cardiometabolic Risk Factors ⬇️

scientific article published on February 11, 2013

Adducin 1 (alpha) Gly460Trp variant is associated with left ventricular geometry in Caucasians and African Americans: The HyperGEN Study

scientific article

Adipocyte iron regulates adiponectin and insulin sensitivity

scientific article

Aggregation of high-normal thyroid-stimulating hormone in hypertensive families

scientific article published on 09 August 2005

Ala92 type 2 deiodinase allele increases risk for the development of hypertension

scientific article published on 15 January 2007

Aldosterone dysregulation with aging predicts renal vascular function and cardiovascular risk

scientific article

Aldosterone production and insulin resistance in healthy adults

scientific article

Altered composition of triglyceride-rich lipoproteins and coronary artery disease in a large case-control study

scientific article published on 22 May 2009

An Exome-Wide Sequencing Study of the GOLDN Cohort Reveals Novel Associations of Coding Variants and Fasting Plasma Lipids

An exome-wide sequencing study of lipid response to high-fat meal and fenofibrate in Caucasians from the GOLDN cohort.

scientific article published on 20 February 2018

Angiotensinogen genotype affects renal and adrenal responses to angiotensin II in essential hypertension

scientific article

Aortic valve sclerosis is associated with preclinical cardiovascular disease in hypertensive adults: the Hypertension Genetic Epidemiology Network study

scientific article

Apolipoprotein B genetic variants modify the response to fenofibrate: a GOLDN study

scientific article

Apolipoprotein H Variant Modifies Plasma Triglyceride Phenotype in Familial Hypercholesterolemia: A Molecular Study in an Eight-generation Hyperlipidemic Family ⬇️

scientific article published on January 1, 2003

Appetite suppressants and valvular heart disease in a population-based sample: the HyperGEN study

scientific article

Association of an intronic haplotype of the LIPC gene with hyperalphalipoproteinemia in two independent populations.

scientific article published on 27 December 2007

Association of coronary artery calcified plaque with clinical coronary heart disease in the National Heart, Lung, and Blood Institute's Family Heart Study.

scientific article published on 17 April 2006

Association of gene variants with lipid levels in response to fenofibrate is influenced by metabolic syndrome status

scientific article published on 21 January 2011

Association of inappropriate left ventricular mass with systolic and diastolic dysfunction: the HyperGEN study

scientific article published in September 2004

Association of left ventricular hypertrophy with metabolic risk factors: the HyperGEN study

scientific article published in February 2002

Association of sICAM-1 and MCP-1 with coronary artery calcification in families enriched for coronary heart disease or hypertension: the NHLBI Family Heart Study

scientific article

Association of the FTO gene with BMI.

scientific article published on 24 January 2008

Association of the melanocortin-4 receptor V103I polymorphism with dietary intake in severely obese persons

scientific article published on September 2008

Associations between angiotensinogen gene variants and left ventricular mass and function in the HyperGEN study

scientific article published in May 2002

Associations of aortic and mitral regurgitation with body composition and myocardial energy expenditure in adults with hypertension: the Hypertension Genetic Epidemiology Network study

article

Benefits of the MEDPED treatment support program for patients with familial hypercholesterolemia

scientific article published on 11 February 2009

Blood pressure responses to acute stress and left ventricular mass (The Hypertension Genetic Epidemiology Network Study).

scientific article published in March 2002

Blood pressure stress reactivity and left ventricular mass in a random community sample of African-American and caucasian men and women

scientific article published in January 2006

Body composition and fat distribution influence systemic hemodynamics in the absence of obesity: the HyperGEN Study

scientific article published in April 2005

Body mass index predicts aldosterone production in normotensive adults on a high-salt diet

scientific article published on 28 August 2007

CYP4A11 T8590C polymorphism, salt-sensitive hypertension, and renal blood flow

scientific article published in October 2011

Cancer incidence and mortality after gastric bypass surgery

scientific article

Caveolin 1 Modulates Aldosterone-Mediated Pathways of Glucose and Lipid Homeostasis

scientific article published on 28 September 2016

Chocolate consumption is inversely associated with calcified atherosclerotic plaque in the coronary arteries: the NHLBI Family Heart Study

scientific article

Chocolate consumption is inversely associated with prevalent coronary heart disease: the National Heart, Lung, and Blood Institute Family Heart Study

scientific article

Circulating soluble ICAM-1 levels shows linkage to ICAM gene cluster region on chromosome 19: the NHLBI Family Heart Study follow-up examination ⬇️

scientific article published on 28 November 2007

Common Variants in 6 Lipid-Related Genes Discovered by High-Resolution DNA Melting Analysis and Their Association with Plasma Lipids ⬇️

scientific article published on July 10, 2011

Controlled analysis of blood pressure sensitivity to sodium intake: interactions with hypertension type

scientific article

Coronary artery disease risk in familial combined hyperlipidemia and familial hypertriglyceridemia: a case-control comparison from the National Heart, Lung, and Blood Institute Family Heart Study

scientific article published on 7 July 2003

Dietary linolenic acid and adjusted QT and JT intervals in the National Heart, Lung, and Blood Institute Family Heart study.

scientific article published in May 2005

Dietary linolenic acid is associated with a lower prevalence of hypertension in the NHLBI Family Heart Study.

scientific article published on 17 January 2005

Dietary linolenic acid is inversely associated with calcified atherosclerotic plaque in the coronary arteries: the National Heart, Lung, and Blood Institute Family Heart Study.

scientific article published on 31 May 2005

Differences in left ventricular structure between black and white hypertensive adults: the Hypertension Genetic Epidemiology Network study

scientific article published on 3 May 2004

Different polymorphisms of the mineralocorticoid receptor gene are associated with either glucocorticoid or mineralocorticoid levels in hypertension

scientific article

Discovery and fine-mapping of loci associated with MUFAs through trans-ethnic meta-analysis in Chinese and European populations

scientific article

Do inflammation and procoagulation biomarkers contribute to the metabolic syndrome cluster?

scientific article

Dysregulated aldosterone secretion in persons of African descent with endothelin-1 gene variants

scientific article published on 7 December 2017

Epigenome-wide study identifies novel methylation loci associated with body mass index and waist circumference

scientific article published on July 2015

Epigenomics and metabolomics reveal the mechanism of the APOA2-saturated fat intake interaction affecting obesity

scientific article published on 01 July 2018

Erythrocyte Fatty Acid Composition and the Metabolic Syndrome: A National Heart, Lung, and Blood Institute GOLDN Study

article

Evaluation of the gene–age interactions in HDL cholesterol, LDL cholesterol, and triglyceride levels: The impact of the SORT1 polymorphism on LDL cholesterol levels is age dependent ⬇️

scientific article published on March 15, 2011

Evidence for a gene influencing heart rate on chromosome 4 among hypertensives.

scientific article published on 16 July 2002

Evidence of QTL on 15q21 for high-density lipoprotein cholesterol: the National Heart, Lung, and Blood Institute Family Heart Study (NHLBI FHS).

scientific article published on 9 March 2006

Expression of Metabolic Syndrome in Women with Severe Obesity

scientific article published on 28 June 2017

Familial aggregation of low-renin hypertension

scientific article published on 01 April 2002

Familial clustering for features of the metabolic syndrome: the National Heart, Lung, and Blood Institute (NHLBI) Family Heart Study

scientific article published in March 2006

Gender difference in diastolic function in hypertension (the HyperGEN study).

scientific article published in May 2002

Genetic analysis of 16 NMR-lipoprotein fractions in humans, the GOLDN study

scientific article published on 29 November 2012

Genetic association between aldehyde dehydrogenase 2 (ALDH2) variation and high-density lipoprotein cholesterol (HDL-C) among non-drinkers in two large population samples in Japan

scientific article

Genetic determinants of nonmodulating hypertension

scientific article published on 6 October 2003

Genetic risk scores associated with baseline lipoprotein subfraction concentrations do not associate with their responses to fenofibrate.

scientific article

Genetic variants associated with VLDL, LDL and HDL particle size differ with race/ethnicity

scientific article

Genome- and CD4+ T-cell methylome-wide association study of circulating trimethylamine-N-oxide in the Genetics of Lipid Lowering Drugs and Diet Network (GOLDN).

scientific article published on 8 March 2017

Genome-wide association studies identified novel loci for non-high-density lipoprotein cholesterol and its postprandial lipemic response.

scientific article

Genome-wide association study indicates variants associated with insulin signaling and inflammation mediate lipoprotein responses to fenofibrate

scientific article published on October 2012

Genome-wide multipoint parametric linkage analysis of pulse pressure in large, extended utah pedigrees

scientific article published on 21 July 2003

Genome-wide scans meta-analysis for pulse pressure

scientific article published on 16 July 2007

Growth hormone receptor variant (L526I) modifies plasma HDL cholesterol phenotype in familial hypercholesterolemia: intra-familial association study in an eight-generation hyperlipidemic kindred

scientific article published on 01 August 2003

Hemodynamic and echocardiographic profiles in African American compared with White offspring of hypertensive parents: the HyperGEN study

scientific article

High-fat meal effect on LDL, HDL, and VLDL particle size and number in the Genetics of Lipid-Lowering Drugs and Diet Network (GOLDN): an interventional study

scientific article published on 18 October 2011

Higher chylomicron remnants and LDL particle numbers associate with CD36 SNPs and DNA methylation sites that reduce CD36.

scientific article published on 11 October 2016

Higher urinary cortisol levels associate with increased cardiovascular risk

scholarly article by Andrea V Haas et al published 1 June 2019 in Endocrine connections

Hyperlipoproteinemia type 3: the forgotten phenotype

scientific article

INSIG2 polymorphism is neither associated with BMI nor with phenotypes of lipoprotein metabolism

scientific article published on 31 January 2008

Identification of a pleiotropic locus on chromosome 7q for a composite left ventricular wall thickness factor and body mass index: the HyperGEN Study

scientific article

Inflammation and hypertension: the interplay of interleukin-6, dietary sodium, and the renin-angiotensin system in humans

scientific article published on 30 June 2011

Influence of fat-free mass on detection of appropriateness of left ventricular mass: the HyperGEN Study

scientific article published in September 2003

Interaction between the LDL-receptor gene bearing a novel mutation and a variant in the apolipoprotein A-II promoter: molecular study in a 1135-member familial hypercholesterolemia kindred

scientific article published in January 2002

Is alcohol consumption associated with calcified atherosclerotic plaque in the coronary arteries and aorta?

scientific article

Joint effects of common genetic variants from multiple genes and pathways on the risk of premature coronary artery disease ⬇️

scientific article published on August 1, 2010

Lack of association of glutamate decarboxylase 2 gene polymorphisms with severe obesity in utah

scientific article published in April 2006

Left atrial systolic force and cardiac markers of preclinical disease in hypertensive patients: the Hypertension Genetic Epidemiology Network (HyperGEN) Study

scientific article published in July 2005

Left ventricular concentric geometry is associated with impaired relaxation in hypertension: the HyperGEN study

scientific article published on 30 November 2004

Leukocyte telomere length and coronary artery calcium

scientific article published on 18 April 2015

Linkage analysis of a composite factor for the multiple metabolic syndrome: the National Heart, Lung, and Blood Institute Family Heart Study

scientific article published in November 2003

Linkage of creatinine clearance to chromosome 10 in Utah pedigrees replicates a locus for end-stage renal disease in humans and renal failure in the fawn-hooded rat

Linkage of creatinine clearance to chromosome 10 in Utah pedigrees replicates a locus for end-stage renal disease in humans and renal failure in the fawn-hooded rat.

scientific article published in October 2002

Linkage of serum creatinine and glomerular filtration rate to chromosome 2 in Utah pedigrees

scientific article

Lipoprotein lipase S447X variant associated with VLDL, LDL and HDL diameter clustering in the MetS

scientific article

Longitudinal and age trends of metabolic syndrome and its risk factors: the Family Heart Study

scientific article

Low-renin hypertension, altered sodium homeostasis, and an alpha-adducin polymorphism

scientific article published in February 2002

Low-salt diet increases insulin resistance in healthy subjects ⬇️

scientific article published on October 30, 2010

Lysine-specific demethylase 1: an epigenetic regulator of salt-sensitive hypertension

scientific article published on 26 April 2012

Lysine-specific demethylase-1 modifies the age effect on blood pressure sensitivity to dietary salt intake ⬇️

scientific article published on 02 October 2012

Methylation at CPT1A locus is associated with lipoprotein subfraction profiles

scientific article

Model-fitting and linkage analysis of sodium–lithium countertransport

article

Nonmodulation as the mechanism for salt sensitivity of blood pressure in individuals with hypertension and type 2 diabetes mellitus

scientific article

PAI-1 in human hypertension: relation to hypertensive groups

scientific article published in August 2002

Plasma triglycerides and type III hyperlipidemia are independently associated with premature familial coronary artery disease

scientific article

Progress in unraveling the genetics of coronary artery disease and myocardial infarction

scientific article published on September 2007

Racial differences in the association of coronary calcified plaque with left ventricular hypertrophy: the National Heart, Lung, and Blood Institute Family Heart Study and Hypertension Genetic Epidemiology Network

scientific article (publication date: 15 May 2006)

Relation of insulin to left ventricular geometry and function in African American and white hypertensive adults: the HyperGEN study

scientific article published in December 2002

Relation of the metabolic syndrome to calcified atherosclerotic plaque in the coronary arteries and aorta

scientific article published in May 2005

Relationship between aldosterone and progesterone in the human menstrual cycle

scientific article

Relationships between endogenous sex hormone concentrations and vascular function in postmenopausal women

scientific article published on 25 September 2007

Renin gene polymorphism: its relationship to hypertension, renin levels and vascular responses

scientific article

Replication and meta-analysis of the gene-environment interaction between body mass index and the interleukin-6 promoter polymorphism with higher insulin resistance

scientific article

Response to Letter Regarding Article, "Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects".

scientific article published on April 2016

SAT-051 Higher Urinary Cortisol Levels Associated with Increased Cardiovascular Risk.

scientific article

Salt consumption-dependent association of the GNB3 gene polymorphism with type 2 DM.

scientific article published on 24 July 2008

Salt sensitivity of blood pressure is associated with polymorphisms in the sodium-bicarbonate cotransporter

scientific article

Segregation analysis of HDL cholesterol in the NHLBI Family Heart Study and in Utah pedigrees.

scientific article

Serum bilirubin levels, UGT1A1 polymorphisms and risk for coronary artery disease

scientific article published on 26 August 2008

Sex Differences in Blood HDL-c, the Total Cholesterol/HDL-c Ratio, and Palmitoleic Acid are Not Associated with Variants in Common Candidate Genes

scientific article published on 27 October 2017

Sex-specific association of the putative fructose transporter SLC2A9 variants with uric acid levels is modified by BMI

scientific article

Sex-specific associations between screen time and lipoprotein subfractions

scientific article

Sibling resemblance for left ventricular structure, contractility, and diastolic filling

scientific article published in September 2002

Smoking, inflammatory patterns and postprandial hypertriglyceridemia

scientific article published on 13 August 2008

Sodium bicarbonate cotransporter polymorphisms are associated with baseline and 10-year follow-up blood pressures

scientific article

Soluble epoxide hydrolase variant (Glu287Arg) modifies plasma total cholesterol and triglyceride phenotype in familial hypercholesterolemia: intrafamilial association study in an eight-generation hyperlipidemic kindred

scientific article

Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects

scientific article

Striatin Gene Polymorphic Variants Are Associated With Salt Sensitive Blood Pressure in Normotensives and Hypertensives

scientific article

TCF7L2 polymorphisms and inflammatory markers before and after treatment with fenofibrate

scientific article published on 12 October 2009

TXNIP gene not associated with familial combined hyperlipidemia in the NHLBI Family Heart Study

scientific article

The ATGL gene is associated with free fatty acids, triglycerides, and type 2 diabetes

scientific article

The Arg16Gly polymorphism of the β2-adrenergic receptor and left ventricular systolic function ⬇️

scientific article published on 01 November 2003

The Fok1 vitamin D receptor gene polymorphism is associated with plasma renin activity in Caucasians ⬇️

scientific article published on June 1, 2011

The association of plasma resistin with dietary sodium manipulation, the renin-angiotensin-aldosterone system, and 25-Hydroxyvitamin D3 in human hypertension ⬇️

scientific article published on March 1, 2011

The association of the angiotensinogen gene with insulin sensitivity in humans: a tagging single nucleotide polymorphism and haplotype approach

scientific article

The effect of CYP7A1 polymorphisms on lipid responses to fenofibrate

scientific article published on March 2012

The effect of IL6-174C/G polymorphism on postprandial triglyceride metabolism in the GOLDN studyboxs

scientific article published on 16 April 2008

The epithelial sodium channel γ-subunit gene and blood pressure: family based association, renal gene expression, and physiological analyses

scientific article published on 17 October 2011

The genetic architecture of fasting plasma triglyceride response to fenofibrate treatment

scientific article published on 23 January 2008

The influence of body mass index and renin-angiotensin-aldosterone system activity on the relationship between 25-hydroxyvitamin D and adiponectin in Caucasian men.

scientific article

The relation between erythrocyte trans fat and triglyceride, VLDL- and HDL-cholesterol concentrations depends on polyunsaturated fat.

scientific article

The relationship between peroxisome proliferator-activated receptor-gamma and renin: a human genetics study

scientific article

Thyroid function and blood pressure homeostasis in euthyroid subjects

scientific article published in July 2004

Triglyceride-rich lipoprotein remnant levels and metabolism: time to adopt these orphan risk factors?

scientific article

Two-dimensional, sex-specific autosomal linkage scan of the number of sodium pump sites

scientific article published in April 2010

Upstream stimulatory factor 1 associated with familial combined hyperlipidemia, LDL cholesterol, and triglycerides

scientific article published on 16 June 2005

Uric acid and the state of the intrarenal renin-angiotensin system in humans

scientific article published in October 2004

Variants identified in a GWAS meta-analysis for blood lipids are associated with the lipid response to fenofibrate

scientific article

Variants in striatin gene are associated with salt-sensitive blood pressure in mice and humans

scientific article

Variants of the caveolin-1 gene: a translational investigation linking insulin resistance and hypertension

scientific article

Vitamin D dependent effects of APOA5 polymorphisms on HDL cholesterol

scientific article published in March 2012

Weight and Metabolic Outcomes 12 Years after Gastric Bypass

scientific article published in September 2017

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