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List of works by Berend Jan Bosch

A Single Point Mutation Creating a Furin Cleavage Site in the Spike Protein Renders Porcine Epidemic Diarrhea Coronavirus Trypsin Independent for Cell Entry and Fusion.

scientific article published on 13 May 2015

A glycerophospholipid-specific pocket in the RVFV class II fusion protein drives target membrane insertion.

scientific article published in November 2017

A human monoclonal antibody blocking SARS-CoV-2 infection

scientific article (preprint)

A human monoclonal antibody blocking SARS-CoV-2 infection

scientific article published on 04 May 2020

A recombinant rabies vaccine expressing the trimeric form of the glycoprotein confers enhanced immunogenicity and protection in outbred mice

scientific article published on 21 June 2014

ATP1A1-mediated Src signaling inhibits coronavirus entry into host cells

scientific article

Accurate Serology for SARS-CoV-2 and common Human Coronaviruses using a Multiplex Approach

scientific article published on 20 August 2020

Adenosine deaminase acts as a natural antagonist for dipeptidyl peptidase 4-mediated entry of the Middle East respiratory syndrome coronavirus

scientific article published on 20 November 2013

Aminopeptidase N is not required for porcine epidemic diarrhea virus cell entry

scientific article published on 28 March 2017

An alphavirus replicon-based vaccine expressing a stabilized Spike antigen induces protective immunity and prevents transmission of SARS-CoV-2 between cats

scientific article published on 20 October 2021

Antibodies against MERS coronavirus in dromedary camels, Kenya, 1992-2013

scientific article

Antibodies against MERS coronavirus in dromedary camels, United Arab Emirates, 2003 and 2013.

scientific article published on April 2014

Blocking transmission of Middle East respiratory syndrome coronavirus (MERS-CoV) in llamas by vaccination with a recombinant spike protein

scientific article published on 01 January 2019

Broad receptor engagement of an emerging global coronavirus may potentiate its diverse cross-species transmissibility.

scientific article

Budded baculovirus particle structure revisited

scientific article

Cathepsin L functionally cleaves the severe acute respiratory syndrome coronavirus class I fusion protein upstream of rather than adjacent to the fusion peptide

scientific article published on 18 June 2008

Cell Attachment Domains of the Porcine Epidemic Diarrhea Virus Spike Protein Are Key Targets of Neutralizing Antibodies

scientific article published on 5 April 2017

Cellular entry of the porcine epidemic diarrhea virus

scientific article

Central ions and lateral asparagine/glutamine zippers stabilize the post-fusion hairpin conformation of the SARS coronavirus spike glycoprotein

scientific article published on 01 May 2005

Changes in SARS-CoV-2 Spike versus Nucleoprotein Antibody Responses Impact the Estimates of Infections in Population-Based Seroprevalence Studies

scientific article published on 03 November 2020

Chimeric camel/human heavy-chain antibodies protect against MERS-CoV infection

scientific article published on 08 August 2018

Cleavage inhibition of the murine coronavirus spike protein by a furin-like enzyme affects cell-cell but not virus-cell fusion

scientific article

Cooperative involvement of the S1 and S2 subunits of the murine coronavirus spike protein in receptor binding and extended host range.

scientific article

Coronavirus cell entry occurs through the endo-/lysosomal pathway in a proteolysis-dependent manner.

scientific article

Coronavirus escape from heptad repeat 2 (HR2)-derived peptide entry inhibition as a result of mutations in the HR1 domain of the spike fusion protein

scientific article published on 12 December 2007

Coronavirus hemagglutinin-esterase and spike proteins co-evolve for functional balance and optimal virion avidity

scientific article published on 06 April 2020

Coronavirus hemagglutinin-esterase and spike proteins coevolve for functional balance and optimal virion avidity

scientific article published on 29 September 2020

Coronavirus spike glycoprotein, extended at the carboxy terminus with green fluorescent protein, is assembly competent

scientific article published on July 2004

Crimean-Congo Hemorrhagic Fever Virus Subunit Vaccines Induce High Levels of Neutralizing Antibodies But No Protection in STAT1 Knockout Mice

scientific article published on December 2015

Crucial steps in the structure determination of a coronavirus spike glycoprotein using cryo-electron microscopy

scientific article

Cryo-electron microscopy structure of a coronavirus spike glycoprotein trimer

scientific article

Cryo-electron tomography of mouse hepatitis virus: Insights into the structure of the coronavirion.

scientific article

Detection of MERS-CoV antigen on formalin-fixed paraffin-embedded nasal tissue of alpacas by immunohistochemistry using human monoclonal antibodies directed against different epitopes of the spike protein

scientific article published on 09 September 2019

Development and Validation of a S1 Protein-Based ELISA for the Specific Detection of Antibodies against Equine Coronavirus

scientific article published in 2019

Development of a SARS-CoV-2 Total Antibody Assay and the Dynamics of Antibody Response over Time in Hospitalized and Nonhospitalized Patients with COVID-19

scientific article published on 30 October 2020

Differential Expression of the Middle East Respiratory Syndrome Coronavirus Receptor in the Upper Respiratory Tracts of Humans and Dromedary Camels

scientific article published on 17 February 2016

Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC

scientific article

Dissecting virus entry: replication-independent analysis of virus binding, internalization, and penetration using minimal complementation of β-galactosidase

scientific article

Geographic Distribution of MERS Coronavirus among Dromedary Camels, Africa

scientific article published in 2014

Geographic distribution of MERS coronavirus among dromedary camels, Africa

scientific article

Glycan shield and epitope masking of a coronavirus spike protein observed by cryo-electron microscopy

scientific article

Glycan shield and fusion activation of a deltacoronavirus spike glycoprotein fine-tuned for enteric infections.

scientific article published in November 2017

Human coronaviruses OC43 and HKU1 bind to 9--acetylated sialic acids via a conserved receptor-binding site in spike protein domain A

scientific article

Human infection with MERS coronavirus after exposure to infected camels, Saudi Arabia, 2013.

scientific article

Identification and characterization of a proteolytically primed form of the murine coronavirus spike proteins after fusion with the target cell.

scientific article

Identification of protein receptors for coronaviruses by mass spectrometry

scientific article published on January 2015

Identification of sialic acid-binding function for the Middle East respiratory syndrome coronavirus spike glycoprotein.

scientific article published on 18 September 2017

Inhibition of Middle East respiratory syndrome coronavirus infection by anti-CD26 monoclonal antibody

scientific article published on 25 September 2013

Inhibition of human coronavirus NL63 infection at early stages of the replication cycle

scientific article published on June 2006

MERS coronavirus neutralizing antibodies in camels, Eastern Africa, 1983-1997.

scientific article

MERS-CoV Infection of Alpaca in a Region Where MERS-CoV is Endemic

scientific article published on 15 June 2016

Manipulation of the porcine epidemic diarrhea virus genome using targeted RNA recombination

scientific article

Membrane ectopeptidases targeted by human coronaviruses

scientific article published on 22 April 2014

Middle East respiratory syndrome coronavirus neutralising serum antibodies in dromedary camels: a comparative serological study.

scientific article published on 9 August 2013

Murine coronavirus with an extended host range uses heparan sulfate as an entry receptor

scientific article published on November 2005

Novel polymeric inhibitors of HCoV-NL63.

scientific article published on 29 November 2012

Occupational Exposure to Dromedaries and Risk for MERS-CoV Infection, Qatar, 2013-2014.

scientific article published in August 2015

Older adults lack SARS CoV-2 cross-reactive T lymphocytes directed to human coronaviruses OC43 and NL63

scientific article published on 08 December 2020

Particulate multivalent presentation of the receptor binding domain induces protective immune responses against MERS-CoV

scientific article published on 01 December 2020

Presence of Middle East respiratory syndrome coronavirus antibodies in Saudi Arabia: a nationwide, cross-sectional, serological study

scientific article published on 8 April 2015

Presence of Middle East respiratory syndrome coronavirus antibodies in Saudi Arabia: a nationwide, cross-sectional, serological study.

scientific article published on 17 May 2015

Proteolytic activation of the porcine epidemic diarrhea coronavirus spike fusion protein by trypsin in cell culture

scientific article published on 7 May 2014

Publisher Correction: A human monoclonal antibody blocking SARS-CoV-2 infection

scientific article published on 14 May 2020

Quantitative and qualitative flow cytometric analysis of nanosized cell-derived membrane vesicles

scientific article published on 22 October 2011

Recombinant soluble, multimeric HA and NA exhibit distinctive types of protection against pandemic swine-origin 2009 A(H1N1) influenza virus infection in ferrets

scientific article

SARS coronavirus, but not human coronavirus NL63, utilizes cathepsin L to infect ACE2-expressing cells

scientific article published on 8 December 2005

SARS-CoV, but not HCoV-NL63, utilizes cathepsins to infect cells: viral entry

scientific article published on January 2006

SARS-CoV-2 mucosal antibody development and persistence and their relation to viral load and COVID-19 symptoms

scientific article published on 23 September 2021

SARS-CoV-2 specific antibody responses in COVID-19 patients

scientific article (preprint)

Sensitive and Specific Detection of Low-Level Antibody Responses in Mild Middle East Respiratory Syndrome Coronavirus Infections

scientific article published in 2019

Serologic Detection of Middle East Respiratory Syndrome Coronavirus Functional Antibodies

scientific article published on 17 May 2020

Serological Screening for Coronavirus Infections in Cats

scientific article published on 13 August 2019

Severe Acute Respiratory Syndrome Coronavirus 2-Specific Antibody Responses in Coronavirus Disease 2019 Patients

scientific article published on 08 April 2020

Severe acute respiratory syndrome coronavirus (SARS-CoV) infection inhibition using spike protein heptad repeat-derived peptides.

scholarly article

Species-Specific Colocalization of Middle East Respiratory Syndrome Coronavirus Attachment and Entry Receptors

scientific article published on 30 July 2019

Spike protein assembly into the coronavirion: exploring the limits of its sequence requirements

scientific article

Spiking the MERS-coronavirus receptor

scientific article published on 13 August 2013

Structural Studies of Coronavirus Fusion Proteins

Structural basis for broad coronavirus neutralization

scientific article published on 29 December 2020

Structural basis for human coronavirus attachment to sialic acid receptors

scientific article published in June 2019

Structures of MERS-CoV spike glycoprotein in complex with sialoside attachment receptors

scientific article published on 02 December 2019

Suitability of transiently expressed antibodies for clinical studies: product quality consistency at different production scales

publication published on 01 January 2022

Tectonic conformational changes of a coronavirus spike glycoprotein promote membrane fusion.

scientific article published on 3 October 2017

The Coronavirus Spike Protein Is a Class I Virus Fusion Protein: Structural and Functional Characterization of the Fusion Core Complex

scientific article

The influenza A virus hemagglutinin glycosylation state affects receptor-binding specificity

scientific article

The receptor binding domain of the new Middle East respiratory syndrome coronavirus maps to a 231-residue region in the spike protein that efficiently elicits neutralizing antibodies

scientific article

The trispecific DARPin ensovibep inhibits diverse SARS-CoV-2 variants

scientific article published in 2022

Towards a solution to MERS: protective human monoclonal antibodies targeting different domains and functions of the MERS-coronavirus spike glycoprotein

scientific article published on 01 January 2019

Transmission of MERS-coronavirus in household contacts

scientific article

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