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List of works by Peter J M Rottier

A Single Point Mutation Creating a Furin Cleavage Site in the Spike Protein Renders Porcine Epidemic Diarrhea Coronavirus Trypsin Independent for Cell Entry and Fusion.

scientific article published on 13 May 2015

A field-proven yeast two-hybrid protocol used to identify coronavirus-host protein-protein interactions

scientific article published on January 2015

A mRNA PCR for the diagnosis of feline infectious peritonitis

scientific article published on 21 December 2004

A protective and safe intranasal RSV vaccine based on a recombinant prefusion-like form of the F protein bound to bacterium-like particles

scientific article

A recombinant rabies vaccine expressing the trimeric form of the glycoprotein confers enhanced immunogenicity and protection in outbred mice

scientific article published on 21 June 2014

A reverse genetics system for avian coronavirus infectious bronchitis virus based on targeted RNA recombination

scientific article

A single immunization with soluble recombinant trimeric hemagglutinin protects chickens against highly pathogenic avian influenza virus H5N1

scientific article (publication date: 14 May 2010)

ATP1A1-mediated Src signaling inhibits coronavirus entry into host cells

scientific article

Acquisition of macrophage tropism during the pathogenesis of feline infectious peritonitis is determined by mutations in the feline coronavirus spike protein

scientific article

Adenosine deaminase acts as a natural antagonist for dipeptidyl peptidase 4-mediated entry of the Middle East respiratory syndrome coronavirus

scientific article published on 20 November 2013

Adverse effects of feline IL-12 during DNA vaccination against feline infectious peritonitis virus

scientific article published in January 2002

An autophagy-independent role for LC3 in equine arteritis virus replication

scientific article published on 26 November 2012

Anguillid herpesvirus 1 transcriptome

scientific article

Biogenesis and dynamics of the coronavirus replicative structures

scientific article

CD200 receptor controls sex-specific TLR7 responses to viral infection

scientific article

Cathepsin L functionally cleaves the severe acute respiratory syndrome coronavirus class I fusion protein upstream of rather than adjacent to the fusion peptide

scientific article published on 18 June 2008

Cell Attachment Domains of the Porcine Epidemic Diarrhea Virus Spike Protein Are Key Targets of Neutralizing Antibodies

scientific article published on 5 April 2017

Cellular entry of the porcine epidemic diarrhea virus

scientific article

Central ions and lateral asparagine/glutamine zippers stabilize the post-fusion hairpin conformation of the SARS coronavirus spike glycoprotein

scientific article published on 01 May 2005

Characterization of Epitope-Specific Anti-Respiratory Syncytial Virus (Anti-RSV) Antibody Responses after Natural Infection and after Vaccination with Formalin-Inactivated RSV

scientific article published on 20 April 2016

Characterization of two new structural glycoproteins, GP(3) and GP(4), of equine arteritis virus

scientific article published on November 2002

Cleavage inhibition of the murine coronavirus spike protein by a furin-like enzyme affects cell-cell but not virus-cell fusion

scientific article

Competition between influenza A virus genome segments

scientific article

Complete genome sequence and taxonomic position of anguillid herpesvirus 1.

scientific article published on 16 December 2009

Cooperative involvement of the S1 and S2 subunits of the murine coronavirus spike protein in receptor binding and extended host range.

scientific article

Coronavirus cell entry occurs through the endo-/lysosomal pathway in a proteolysis-dependent manner.

scientific article

Coronavirus escape from heptad repeat 2 (HR2)-derived peptide entry inhibition as a result of mutations in the HR1 domain of the spike fusion protein

scientific article published on 12 December 2007

Coronavirus genetically redirected to the epidermal growth factor receptor exhibits effective antitumor activity against a malignant glioblastoma

scientific article published on 13 May 2009

Coronavirus spike glycoprotein, extended at the carboxy terminus with green fluorescent protein, is assembly competent

scientific article published on July 2004

Coronavirus: epidemiology, genome replication and the interactions with their hosts

scientific article published on 19 February 2016

Coronaviruses as vectors: position dependence of foreign gene expression

scientific article published on November 2003

Coronaviruses as vectors: stability of foreign gene expression

scientific article published on October 2005

Coronaviruses maintain viability despite dramatic rearrangements of the strictly conserved genome organization

scientific article

Crucial steps in the structure determination of a coronavirus spike glycoprotein using cryo-electron microscopy

scientific article

Cryo-electron microscopy structure of a coronavirus spike glycoprotein trimer

scientific article

Cryo-electron tomography of mouse hepatitis virus: Insights into the structure of the coronavirion.

scientific article

Deletion of accessory genes 3a, 3b, 5a or 5b from avian coronavirus infectious bronchitis virus induces an attenuated phenotype both in vitro and in vivo

article

Differential susceptibility of macrophages to serotype II feline coronaviruses correlates with differences in the viral spike protein

scientific article published on 21 June 2018

Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC

scientific article

Dissecting virus entry: replication-independent analysis of virus binding, internalization, and penetration using minimal complementation of β-galactosidase

scientific article

Dissection of the influenza A virus endocytic routes reveals macropinocytosis as an alternative entry pathway

scientific article

Dynamics of coronavirus replication-transcription complexes.

scientific article

European surveillance of emerging pathogens associated with canine infectious respiratory disease

scientific article

Evolution of the hemagglutinin protein of the new pandemic H1N1 influenza virus: maintaining optimal receptor binding by compensatory substitutions.

scientific article

Experimental infection with neuropathogenic equid herpesvirus type 1 (EHV-1) in adult horses

scientific article published on 01 September 2009

Expression of epidermal growth factor receptor in canine osteosarcoma: association with clinicopathological parameters and prognosis

scientific article

Feline infectious peritonitis: insights into feline coronavirus pathobiogenesis and epidemiology based on genetic analysis of the viral 3c gene.

scientific article published on 4 November 2009

Formation of disulfide-linked complexes between the three minor envelope glycoproteins (GP2b, GP3, and GP4) of equine arteritis virus

scientific article

Gain, preservation, and loss of a group 1a coronavirus accessory glycoprotein

scientific article published on 30 July 2008

Generation of a candidate live marker vaccine for equine arteritis virus by deletion of the major virus neutralization domain

scientific article published on August 2003

Genetic versus antigenic differences among highly pathogenic H5N1 avian influenza A viruses: Consequences for vaccine strain selection

scientific article published on 27 January 2017

Genome-wide gene expression analysis of anguillid herpesvirus 1.

scientific article

Glycan-dependent immunogenicity of recombinant soluble trimeric hemagglutinin

scientific article

Homotypic interactions of the infectious bursal disease virus proteins VP3, pVP2, VP4, and VP5: mapping of the interacting domains

scientific article published in August 2003

Hosting the severe acute respiratory syndrome coronavirus: specific cell factors required for infection

scientific article published on 27 June 2006

Identification and characterization of a proteolytically primed form of the murine coronavirus spike proteins after fusion with the target cell.

scientific article

Identification and localization of the structural proteins of anguillid herpesvirus 1.

scientific article

Identification of host factors involved in coronavirus replication by quantitative proteomics analysis

scientific article published on 6 December 2010

Improved microarray gene expression profiling of virus-infected cells after removal of viral RNA

scientific article

Infectious bursal disease virus capsid protein VP3 interacts both with VP1, the RNA-dependent RNA polymerase, and with viral double-stranded RNA.

scientific article published on November 2002

Influenza A virus entry into cells lacking sialylated N-glycans

scientific article

Inhibition of human coronavirus NL63 infection at early stages of the replication cycle

scientific article published on June 2006

Inhibition of the ubiquitin-proteasome system affects influenza A virus infection at a postfusion step

scientific article

Intra- and intermolecular disulfide bonds of the GP2b glycoprotein of equine arteritis virus: relevance for virus assembly and infectivity

scientific article published on December 2003

Live, attenuated coronavirus vaccines through the directed deletion of group-specific genes provide protection against feline infectious peritonitis

scientific article published on April 2004

Manipulation of the coronavirus genome using targeted RNA recombination with interspecies chimeric coronaviruses

scientific article published in January 2008

Manipulation of the porcine epidemic diarrhea virus genome using targeted RNA recombination

scientific article

Membrane rearrangements mediated by coronavirus nonstructural proteins 3 and 4.

scientific article

Middle East respiratory syndrome coronavirus neutralising serum antibodies in dromedary camels: a comparative serological study.

scientific article published on 9 August 2013

Mobility and interactions of coronavirus nonstructural protein 4.

scientific article

Molecular interactions in the assembly of coronaviruses

scientific article published on 01 January 2005

Mouse Hepatitis Coronavirus RNA Replication Depends on GBF1-Mediated ARF1 Activation

scientific article (publication date: 13 June 2008)

Mouse hepatitis coronavirus replication induces host translational shutoff and mRNA decay, with concomitant formation of stress granules and processing bodies

scientific article published on 08 May 2007

Murine coronavirus with an extended host range uses heparan sulfate as an entry receptor

scientific article published on November 2005

Non-invasive imaging of mouse hepatitis coronavirus infection reveals determinants of viral replication and spread in vivo.

scientific article published on 10 February 2009

Only two residues are responsible for the dramatic difference in receptor binding between swine and new pandemic H1 hemagglutinin

scientific article

Passive inhalation of dry powder influenza vaccine formulations completely protects chickens against H5N1 lethal viral challenge

scientific article published on 09 October 2018

Pathogenic characteristics of persistent feline enteric coronavirus infection in cats

scientific article

Protective efficacy of Newcastle disease virus expressing soluble trimeric hemagglutinin against highly pathogenic H5N1 influenza in chickens and mice

scientific article

Proteolytic activation of the porcine epidemic diarrhea coronavirus spike fusion protein by trypsin in cell culture

scientific article published on 7 May 2014

Pulmonary immunization of chickens using non-adjuvanted spray-freeze dried whole inactivated virus vaccine completely protects against highly pathogenic H5N1 avian influenza virus

scientific article published on 5 October 2014

Quantitative proteomic identification of host factors involved in the Salmonella typhimurium infection cycle

scientific article

Rapid Emergence of Highly Pathogenic Avian Influenza Subtypes from a Subtype H5N1 Hemagglutinin Variant

scientific article published on May 2015

Recombinant Soluble Respiratory Syncytial Virus F Protein That Lacks Heptad Repeat B, Contains a GCN4 Trimerization Motif and Is Not Cleaved Displays Prefusion-Like Characteristics.

scientific article published on 24 June 2015

Recombinant live attenuated avian coronavirus vaccines with deletions in the accessory genes 3ab and/or 5ab protect against infectious bronchitis in chickens

scientific article published on 20 January 2018

Recombinant soluble, multimeric HA and NA exhibit distinctive types of protection against pandemic swine-origin 2009 A(H1N1) influenza virus infection in ferrets

scientific article

Role of Endocytosis and Low pH in Murine Hepatitis Virus Strain A59 Cell Entry

scientific article (publication date: October 2007)

SARS coronavirus, but not human coronavirus NL63, utilizes cathepsin L to infect ACE2-expressing cells

scientific article published on 8 December 2005

Sequence analysis of feline coronaviruses and the circulating virulent/avirulent theory.

scientific article published on April 2011

Severe acute respiratory syndrome coronavirus (SARS-CoV) infection inhibition using spike protein heptad repeat-derived peptides.

scholarly article

Single-cell analysis of population context advances RNAi screening at multiple levels

scientific article

Spike protein assembly into the coronavirion: exploring the limits of its sequence requirements

scientific article

Spike protein fusion peptide and feline coronavirus virulence.

scientific article

Structural protein requirements in equine arteritis virus assembly

scientific article published on December 2004

Switching species tropism: an effective way to manipulate the feline coronavirus genome

scientific article

The 29-nucleotide deletion present in human but not in animal severe acute respiratory syndrome coronaviruses disrupts the functional expression of open reading frame 8.

scientific article

The Coronavirus Spike Protein Is a Class I Virus Fusion Protein: Structural and Functional Characterization of the Fusion Core Complex

scientific article

The coronavirus nucleocapsid protein is dynamically associated with the replication-transcription complexes

scientific article

The glycosylation status of the murine hepatitis coronavirus M protein affects the interferogenic capacity of the virus in vitro and its ability to replicate in the liver but not the brain

scientific article published in August 2003

The group-specific murine coronavirus genes are not essential, but their deletion, by reverse genetics, is attenuating in the natural host

scientific article published on 01 April 2002

The influenza A virus hemagglutinin glycosylation state affects receptor-binding specificity

scientific article

The intraleader AUG nucleotide sequence context is important for equine arteritis virus replication

scientific article published on August 2006

The proteasome inhibitor Velcade enhances rather than reduces disease in mouse hepatitis coronavirus-infected mice.

scientific article published on 19 May 2010

The receptor binding domain of the new Middle East respiratory syndrome coronavirus maps to a 231-residue region in the spike protein that efficiently elicits neutralizing antibodies

scientific article

The ubiquitin-proteasome system plays an important role during various stages of the coronavirus infection cycle

scientific article

Topology and Membrane Anchoring of the Coronavirus Replication Complex: Not All Hydrophobic Domains of nsp3 and nsp6 Are Membrane Spanning

scientific article (publication date: December 2008)

Two genetically closely related pigeon paramyxovirus type 1 (PPMV-1) variants with identical velogenic fusion protein cleavage sites but with strongly contrasting virulence

scientific article

Type I interferon receptor-independent and -dependent host transcriptional responses to mouse hepatitis coronavirus infection in vivo

scientific article

Virulence of Newcastle disease virus: what is known so far?

scientific article published on 23 December 2011

Visualizing coronavirus RNA synthesis in time by using click chemistry

scientific article

West Nile virus also in the Netherlands?

scientific article published on September 2004

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