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List of works by Ashley M Vaughan

A Plasmodium parasite with complete late liver stage arrest protects against pre-erythrocytic and erythrocytic stage infection in mice

scientific article published on 12 February 2018

A Plasmodium yoelii Mei2-Like RNA Binding Protein Is Essential for Completion of Liver Stage Schizogony

scientific article (publication date: May 2016)

A dispensable Plasmodium locus for stable transgene expression

scientific article

A genetically attenuated parasite vaccine does not require liver stage persistence to elicit sterile protective immunity against sporozoite-induced malaria in mice

scientific article published in April 2010

A scalable assessment of Plasmodium falciparum transmission in the standard membrane-feeding assay, using transgenic parasites expressing green fluorescent protein-luciferase

scientific article

A systematic analysis of the early transcribed membrane protein family throughout the life cycle of Plasmodium yoelii

scientific article published on 31 August 2011

A transgenic Plasmodium falciparum NF54 strain that expresses GFP-luciferase throughout the parasite life cycle

scientific article published on 27 October 2012

An efficient strategy for gene targeting and phenotypic assessment in the Plasmodium yoelii rodent malaria model

scientific article published on 15 December 2007

Assessment and improvement of the Plasmodium yoelii yoelii genome annotation through comparative analysis

scientific article published on July 2008

Beyond Blood Smears: Qualification of Plasmodium 18S rRNA as a Biomarker for Controlled Human Malaria Infections.

scientific article published in June 2019

Blood Stage Malaria Disrupts Humoral Immunity to the Pre-erythrocytic Stage Circumsporozoite Protein

scientific article

CD40 is required for protective immunity against liver stage Plasmodium infection

scientific article

Complete Plasmodium falciparum liver-stage development in liver-chimeric mice

scientific article

Complete attenuation of genetically engineered Plasmodium falciparum sporozoites in human subjects

scientific article published on January 2017

Cyclic GMP balance is critical for malaria parasite transmission from the mosquito to the mammalian host

scientific article (publication date: 17 March 2015)

Enzymes involved in plastid-targeted phosphatidic acid synthesis are essential for Plasmodium yoelii liver-stage development

scientific article (publication date: February 2014)

Genetic mapping of fitness determinants across the malaria parasite Plasmodium falciparum life cycle

scientific article published on 14 October 2019

Genetically attenuated malaria parasites as vaccines

scientific article published on 14 June 2017

Genetically engineered, attenuated whole-cell vaccine approaches for malaria

scientific article published on 29 January 2010

Humoral protection against mosquito bite-transmitted Plasmodium falciparum infection in humanized mice

scientific article published on 9 October 2017

Immunization of mice with live-attenuated late liver stage-arresting Plasmodium yoelii parasites generates protective antibody responses to preerythrocytic stages of malaria

scientific article

Interferon-mediated innate immune responses against malaria parasite liver stages

scientific article published on 3 April 2014

Interrogating the Plasmodium Sporozoite Surface: Identification of Surface-Exposed Proteins and Demonstration of Glycosylation on CSP and TRAP by Mass Spectrometry-Based Proteomics

scientific article (publication date: April 2016)

Isolation and sequence analysis of P450 genes from a pyrethroid resistant colony of the major malaria vector Anopheles funestus

scientific article published in December 2005

Kinetic flux profiling elucidates two independent acetyl-CoA biosynthetic pathways in Plasmodium falciparum

scientific article published on 25 October 2013

Malaria Parasite Liver Infection and Exoerythrocytic Biology

scientific article

Malaria parasite development in the mosquito and infection of the mammalian host

scientific article

Malaria parasite pre-erythrocytic stage infection: gliding and hiding

scientific article published on 11 September 2008

Malaria vaccine development: persistent challenges

scientific article published on 21 April 2012

Measurement of Antibody-Mediated Reduction of Plasmodium yoelii Liver Burden by Bioluminescent Imaging

scientific article published on January 2015

Mechanisms of stage-transcending protection following immunization of mice with late liver stage-arresting genetically attenuated malaria parasites

scientific article published on 14 May 2015

Model for in vivo assessment of humoral protection against malaria sporozoite challenge by passive transfer of monoclonal antibodies and immune serum

scientific article published on 09 December 2013

Perturbations of Plasmodium Puf2 expression and RNA-seq of Puf2-deficient sporozoites reveal a critical role in maintaining RNA homeostasis and parasite transmissibility

scientific article published on 27 February 2013

PfCap380 as a marker for Plasmodium falciparum oocyst development in vivo and in vitro

article

Plasmodium falciparum genetic crosses in a humanized mouse model

scientific article

Plasmodium pyruvate dehydrogenase activity is only essential for the parasite's progression from liver infection to blood infection.

scientific article published in February 2010

Plasmodium vivax liver stage development and hypnozoite persistence in human liver-chimeric mice

scientific article published on 19 March 2015

Plasmodium yoelii S4/CelTOS is important for sporozoite gliding motility and cell traversal

scientific article published on 18 December 2017

Plasmodium yoelii inhibitor of cysteine proteases is exported to exomembrane structures and interacts with yoelipain-2 during asexual blood-stage development

scientific article published on 14 March 2013

Proteogenomic analysis of the total and surface-exposed proteomes of Plasmodium vivax salivary gland sporozoites

scientific article

Quantitative bioluminescent imaging of pre-erythrocytic malaria parasite infection using luciferase-expressing Plasmodium yoelii

scientific article

Redefining the role of de novo fatty acid synthesis in Plasmodium parasites.

scientific article published on 12 October 2009

Superior antimalarial immunity after vaccination with late liver stage-arresting genetically attenuated parasites

scientific article

Suppression of host p53 is critical for Plasmodium liver-stage infection

scientific article published on 7 March 2013

Susceptibility to Plasmodium yoelii Preerythrocytic Infection in BALB/c Substrains Is Determined at the Point of Hepatocyte Invasion ⬇️

scientific article (publication date: 13 October 2014)

Th1-like Plasmodium-Specific Memory CD4+ T Cells Support Humoral Immunity

scientific article published in November 2017

Th1-like Plasmodium-Specific Memory CD4+ T Cells Support Humoral Immunity

scientific article published on 01 April 2018

That Was Then But This Is Now: Malaria Research in the Time of an Eradication Agenda

scientific article

The Anopheles gambiae detoxification chip: a highly specific microarray to study metabolic-based insecticide resistance in malaria vectors

scientific article

The Micronemal Proteins P36 and P52 Act in Concert to Establish the Replication-Permissive Compartment Within Infected Hepatocytes

article

Total and putative surface proteomics of malaria parasite salivary gland sporozoites.

scientific article published on 16 January 2013

Type II fatty acid biosynthesis is essential for Plasmodium falciparum sporozoite development in the midgut of Anopheles mosquitoes

scientific article (publication date: May 2014)

Type II fatty acid synthesis is essential only for malaria parasite late liver stage development

scientific article published on 03 December 2008

Vaccination using radiation- or genetically attenuated live sporozoites

scientific article published in January 2013

Whole parasite vaccination approaches for prevention of malaria infection

scientific article published on 07 March 2012

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