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List of works by John J Aponte

A 10 year study of the cause of death in children under 15 years in Manhiça, Mozambique

scientific article

A combined analysis of immunogenicity, antibody kinetics and vaccine efficacy from phase 2 trials of the RTS,S malaria vaccine

scientific article

A country-wide malaria survey in Mozambique. II. Malaria attributable proportion of fever and establishment of malaria case definition in children across different epidemiological settings

scientific article published on 21 April 2009

A phase 3 trial of RTS,S/AS01 malaria vaccine in African infants

scientific article

A prospective cohort study to assess the micro-epidemiology of Plasmodium falciparum clinical malaria in Ilha Josina Machel (Manhiça, Mozambique).

scientific article published on 31 August 2016

A randomized comparison of two anemia treatment regimens in Tanzanian children

scientific article

A randomized placebo-controlled trial of intermittent preventive treatment in pregnant women in the context of insecticide treated nets delivered through the antenatal clinic

scientific article

Age interactions in the development of naturally acquired immunity to Plasmodium falciparum and its clinical presentation

scientific article

Age-dependent IgG subclass responses to Plasmodium falciparum EBA-175 are differentially associated with incidence of malaria in Mozambican children

scientific article published on 14 December 2011

Anaemia in hospitalised preschool children from a rural area in Mozambique: a case control study in search for aetiological agents

scientific article

Arterial embolisation or chemoembolisation versus symptomatic treatment in patients with unresectable hepatocellular carcinoma: a randomised controlled trial

scientific article (publication date: 18 May 2002)

BCG vaccination in southern rural Mozambique: an overview of coverage and its determinants based on data from the demographic and health surveillance system in the district of Manhiça

scientific article published on 13 February 2018

Changing Trends in P. falciparum Burden, Immunity, and Disease in Pregnancy

scientific article published on October 2015

Clinical malaria in African pregnant women

scientific article

Concordance of three alternative gestational age assessments for pregnant women from four African countries: A secondary analysis of the MIPPAD trial

scientific article published in PLoS ONE

Controlled human malaria infection by intramuscular and direct venous inoculation of cryopreserved Plasmodium falciparum sporozoites in malaria-naïve volunteers: effect of injection volume and dose on infectivity rates

scientific article published on 7 August 2015

Correction: Age Interactions in the Development of Naturally Acquired Immunity to Plasmodium falciparum and Its Clinical Presentation.

scientific article

Distinct TH1 and TH2 cellular responses associated with malaria protection and risk in RTS,S/AS01E vaccinees

scientific article

Drug exposure and pregnancy outcome in Mozambique

scientific article published in February 2012

Duration of protection with RTS,S/AS02A malaria vaccine in prevention of Plasmodium falciparum disease in Mozambican children: single-blind extended follow-up of a randomised controlled trial

scientific article published on December 2005

Duration of vaccine efficacy against malaria: 5th year of follow-up in children vaccinated with RTS,S/AS02 in Mozambique

scientific article published on 11 March 2014

Economic evaluation of an alternative drug to sulfadoxine-pyrimethamine as intermittent preventive treatment of malaria in pregnancy

scientific article

Effects of HIV infection on maternal and neonatal health in southern Mozambique: A prospective cohort study after a decade of antiretroviral drugs roll out.

scientific article

Efficacy and safety of intermittent preventive treatment with sulfadoxine-pyrimethamine for malaria in African infants: a pooled analysis of six randomised, placebo-controlled trials

scientific article published on 16 September 2009

Efficacy of the RTS,S/AS02A vaccine against Plasmodium falciparum infection and disease in young African children: randomised controlled trial

scientific article

Evaluation of efficacy of community-based vs. institutional-based direct observed short-course treatment for the control of tuberculosis in Kilombero district, Tanzania

scientific article published in March 2003

Evaluation of two formulations of adjuvanted RTS, S malaria vaccine in children aged 3 to 5 years living in a malaria-endemic region of Mozambique: a Phase I/IIb randomized double-blind bridging trial

scientific article published on 26 March 2007

Feasibility of flow cytometry for measurements of Plasmodium falciparum parasite burden in studies in areas of malaria endemicity by use of bidimensional assessment of YOYO-1 and autofluorescence

scientific article published on 12 January 2011

Field trials

scientific article published in January 2002

First results of phase 3 trial of RTS,S/AS01 malaria vaccine in African children

scientific article

Four year immunogenicity of the RTS,S/AS02(A) malaria vaccine in Mozambican children during a phase IIb trial

scientific article published on 7 April 2011

HIV Incidence and Spatial Clustering in a Rural Area of Southern Mozambique

scientific article

Haematological and biochemical indices in young African children: in search of reference intervals.

scientific article published in November 2006

High production of pro-inflammatory cytokines by maternal blood mononuclear cells is associated with reduced maternal malaria but increased cord blood infection

scientific article

Identification of chronic hepatitis C patients without hepatic fibrosis by a simple predictive model

scientific article published in October 2002

Identifying Immune Correlates of Protection Against Plasmodium falciparum Through a Novel Approach to Account for Heterogeneity in Malaria Exposure

scientific article published in February 2018

IgG against Plasmodium falciparum variant surface antigens and growth inhibitory antibodies in Mozambican children receiving intermittent preventive treatment with sulfadoxine-pyrimethamine

scientific article published on 25 December 2010

IgM and IgG against Plasmodium falciparum lysate as surrogates of malaria exposure and protection during pregnancy

scientific article

Immunogenicity of the RTS,S/AS01 malaria vaccine and implications for duration of vaccine efficacy: secondary analysis of data from a phase 3 randomised controlled trial

scientific article

Impact of age of first exposure to Plasmodium falciparum on antibody responses to malaria in children: a randomized, controlled trial in Mozambique

scientific article published on 27 March 2014

Impact of intermittent preventive treatment with sulfadoxine-pyrimethamine on antibody responses to erythrocytic-stage Plasmodium falciparum antigens in infants in Mozambique

scientific article published on 21 May 2008

Impact of malaria at the end of pregnancy on infant mortality and morbidity

scientific article

Impact of maternal human immunodeficiency virus infection on birth outcomes and infant survival in rural Mozambique.

scientific article

Impact of the Mass Drug Administration for malaria in response to the Ebola outbreak in Sierra Leone

scientific article

Impact of the RTS,S malaria vaccine candidate on naturally acquired antibody responses to multiple asexual blood stage antigens

scientific article

Incidence of Tuberculosis Among Young Children in Rural Mozambique

scientific article

Insights into long-lasting protection induced by RTS,S/AS02A malaria vaccine: further results from a phase IIb trial in Mozambican children

scientific article

Intermittent preventive antimalarial treatment for Tanzanian infants: follow-up to age 2 years of a randomised, placebo-controlled trial

scientific article

Intermittent preventive treatment for malaria control administered at the time of routine vaccinations in Mozambican infants: a randomized, placebo-controlled trial.

scientific article published on 30 June 2006

Intermittent preventive treatment for malaria in Papua New Guinean infants exposed to Plasmodium falciparum and P. vivax: a randomized controlled trial

scientific article published in 2012

Intermittent preventive treatment of malaria in pregnancy with mefloquine in HIV-infected women receiving cotrimoxazole prophylaxis: a multicenter randomized placebo-controlled trial

scientific article (publication date: September 2014)

Intermittent preventive treatment of malaria in pregnancy with mefloquine in HIV-negative women: a multicentre randomized controlled trial

scientific article (publication date: September 2014)

Intermittent preventive treatment with sulfadoxine-pyrimethamine does not modify plasma cytokines and chemokines or intracellular cytokine responses to Plasmodium falciparum in Mozambican children

scientific article

Lack of associations of α(+)-thalassemia with the risk of Plasmodium falciparum and Plasmodium vivax infection and disease in a cohort of children aged 3-21 months from Papua New Guinea

scientific article published on 17 October 2012

Levels and trends of demographic indices in southern rural Mozambique: evidence from demographic surveillance in Manhiça district

scientific article published on 30 November 2006

Long-term safety and efficacy of the RTS,S/AS02A malaria vaccine in Mozambican children

scientific article published on August 2009

Malaria in pregnancy in rural Mozambique: the role of parity, submicroscopic and multiple Plasmodium falciparum infections

scientific article published in January 2002

Malaria in rural Mozambique. Part I: children attending the outpatient clinic

scientific article

Malaria in rural Mozambique. Part II: children admitted to hospital

scientific article published on 26 February 2008

Malaria in southern Mozambique: incidence of clinical malaria in children living in a rural community in Manhiça district

scientific article published in November 2003

Malaria in southern Mozambique: malariometric indicators and malaria case definition in Manhiça district

scientific article

Malaria infection does not appear to modify the risk of bronchiolitis early in life

scientific article

Malaria prevention with IPTp during pregnancy reduces neonatal mortality

scientific article

Malaria: Global progress 2000 - 2015 and future challenges

scientific article published on 9 June 2016

Mefloquine for preventing malaria in pregnant women

scientific article

Mefloquine for preventing malaria in pregnant women

scientific article published on 14 November 2018

Mefloquine for preventing malaria in pregnant women.

scientific article published on 21 March 2018

Modeling a field trial of the RTS,S/AS02A malaria vaccine

scientific article published on August 2006

Molecular markers of resistance to sulfadoxine-pyrimethamine during intermittent preventive treatment for malaria in Mozambican infants

scientific article published in June 2008

Mortality, Morbidity, and Developmental Outcomes in Infants Born to Women Who Received Either Mefloquine or Sulfadoxine-Pyrimethamine as Intermittent Preventive Treatment of Malaria in Pregnancy: A Cohort Study

scientific article

No rebound of morbidity following intermittent preventive sulfadoxine-pyrimethamine treatment of malaria in infants in Gabon

scientific article published in December 2009

Performance of multiplex commercial kits to quantify cytokine and chemokine responses in culture supernatants from Plasmodium falciparum stimulations

scientific article

Plasmodium falciparum multiple infections in Mozambique, its relation to other malariological indices and to prospective risk of malaria morbidity

scientific article published in January 2003

Plasmodium falciparum-specific cellular immune responses after immunization with the RTS,S/AS02D candidate malaria vaccine in infants living in an area of high endemicity in Mozambique

scientific article published on 03 August 2009

Profile: Manhiça Health Research Centre (Manhiça HDSS).

scientific article published in October 2013

RTS,S vaccination is associated with serologic evidence of decreased exposure to Plasmodium falciparum liver- and blood-stage parasites

scientific article

RTS,S/AS01E Malaria Vaccine Induces Memory and Polyfunctional T Cell Responses in a Pediatric African Phase III Trial

scientific article published on 23 August 2017

RTS,S/AS02A malaria vaccine does not induce parasite CSP T cell epitope selection and reduces multiplicity of infection

scientific article published on 19 May 2006

Randomized controlled safety and efficacy trial of 2 vitamin A supplementation schedules in Tanzanian infants

scientific article

Reduced risk of Plasmodium vivax malaria in Papua New Guinean children with Southeast Asian ovalocytosis in two cohorts and a case-control study

scientific article published in 2012

Relationship between haemoglobin and haematocrit in the definition of anaemia

scientific article

Resisting and tolerating P. falciparum in pregnancy under different malaria transmission intensities

scientific article

Risk factors for presentation to hospital with severe anaemia in Tanzanian children: a case-control study

scientific article

Safety of the RTS,S/AS02A malaria vaccine in Mozambican children during a Phase IIb trial

scientific article

Safety of the RTS,S/AS02D candidate malaria vaccine in infants living in a highly endemic area of Mozambique: a double blind randomised controlled phase I/IIb trial

scientific article

Safety, immunogenicity and duration of protection of the RTS,S/AS02(D) malaria vaccine: one year follow-up of a randomized controlled phase I/IIb trial

scientific article (publication date: 4 November 2010)

Severe malaria and concomitant bacteraemia in children admitted to a rural Mozambican hospital

scientific article published on 22 June 2009

Small intestinal bacterial overgrowth in human cirrhosis is associated with systemic endotoxemia

scientific article

Spatio-seasonal modeling of the incidence rate of malaria in Mozambique

scientific article published on 31 October 2008

Spatio-temporal analysis of mortality among children under the age of five in Manhiça (Mozambique) during the period 1997-2005 ⬇️

scientific article published on February 18, 2011

Statistical methodology for the evaluation of vaccine efficacy in a phase III multi-centre trial of the RTS, S/AS01 malaria vaccine in African children

scientific article

Sub-microscopic infections and long-term recrudescence of Plasmodium falciparum in Mozambican pregnant women

scientific article published on 09 January 2009

The changing epidemiology of malaria in Ifakara Town, southern Tanzania

scientific article published on January 2004

The cost-effectiveness of intermittent preventive treatment for malaria in infants in Sub-Saharan Africa

scientific article

The effects of short-term iron supplementation on iron status in infants in malaria-endemic areas.

scientific article

The epidemiology of malaria in adults in a rural area of southern Mozambique

scientific article published on 17 January 2007

The performance of the expanded programme on immunization in a rural area of Mozambique

scientific article published on 18 June 2015

The role of age and exposure to Plasmodium falciparum in the rate of acquisition of naturally acquired immunity: a randomized controlled trial

scientific article (publication date: 2012)

The safety and efficacy of sulfadoxine-pyrimethamine, amodiaquine, and their combination in the treatment of uncomplicated Plasmodium falciparum malaria

scientific article published on July 2002

Unfractionated heparin is associated with a lower rise of serum vascular cell adhesion molecule-1 in acute ischemic stroke patients

scientific article (publication date: 16 August 2002)

Varying efficacy of intermittent preventive treatment for malaria in infants in two similar trials: public health implications

scientific article

Weighing for results: assessing the effect of IPTp

scientific article published in April 2013

Young adolescent girls are at high risk for adverse pregnancy outcomes in sub-Saharan Africa: an observational multicountry study

scientific article published on 29 June 2016

drLumi: An open-source package to manage data, calibrate, and conduct quality control of multiplex bead-based immunoassays data analysis

scientific article published on 14 November 2017

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