List of works - Gosse J Adema

An alternatively spliced CXCL16 isoform expressed by dendritic cells is a secreted chemoattractant for CXCR6+ cells

scientific article published on 24 February 2010

C-type lectin receptors on dendritic cells and Langerhans cells

scientific article

Clinical significance of the nuclear receptor co-regulator DC-SCRIPT in breast cancer: an independent retrospective validation study.

scientific article

Commonly used prophylactic vaccines as an alternative for synthetically produced TLR ligands to mature monocyte-derived dendritic cells

scientific article published on 27 April 2010

DC-SCRIPT is a novel regulator of the tumor suppressor gene CDKN2B and induces cell cycle arrest in ERα-positive breast cancer cells

scientific article

DC-SCRIPT: nuclear receptor modulation and prognostic significance in primary breast cancer

scientific article

DC-STAMP interacts with ER-resident transcription factor LUMAN which becomes activated during DC maturation

scientific article

DC-STAMP knock-down deregulates cytokine production and T-cell stimulatory capacity of LPS-matured dendritic cells

scientific article

Dectin-1 interaction with tetraspanin CD37 inhibits IL-6 production

scientific article

Dendritic cells: tools and targets for antitumor vaccination

scientific article

Development of a high-field MR-guided HIFU setup for thermal and mechanical ablation methods in small animals

scientific article

Different faces of the heme-heme oxygenase system in inflammation

scientific article

Differential Toll-like receptor recognition and induction of cytokine profile by Bifidobacterium breve and Lactobacillus strains of probiotics.

scientific article

Differential expansion of circulating human MDSC subsets in patients with cancer, infection and inflammation

scientific article published on 01 September 2020

Differential expression regulation of the alpha and beta subunits of the PA28 proteasome activator in mature dendritic cells

scientific journal article

Differential susceptibility and response of primary human myeloid BDCA1(+) dendritic cells to infection with different Enteroviruses

scientific article

Enhanced lipid biosynthesis in human tumor-induced macrophages contributes to their protumoral characteristics

scientific article published on 01 September 2020

Enterovirus-infected β-cells induce distinct response patterns in BDCA1+ and BDCA3+ human dendritic cells

scientific article published on 25 March 2015

HDAC inhibitors and immunotherapy; a double edged sword?

scientific article

Human TLR10 is an anti-inflammatory pattern-recognition receptor

scientific article

Human dectin-1 deficiency and mucocutaneous fungal infections

scientific article

Humoral anti-KLH responses in cancer patients treated with dendritic cell-based immunotherapy are dictated by different vaccination parameters ⬇️

scientific article published on April 21, 2012

Identification and characterization of DC-SCRIPT, a novel dendritic cell-expressed member of the zinc finger family of transcriptional regulators

scientific article

Immune regulation by regulatory T cells: implications for transplantation

scientific article

Immunotherapy and the Interventional Oncologist: Challenges and Opportunities-A Society of Interventional Oncology White Paper

scientific article published on 23 April 2019

In situ expression of tumor antigens by messenger RNA-electroporated dendritic cells in lymph nodes of melanoma patients

scientific article

Interleukin-12 has no effect on vascular density, perfusion, hypoxia and proliferation of an implanted human squamous cell carcinoma xenograft tumour despite up-regulation of ICAM-1.

scientific article published in March 2005

Intra-adrenal murine TH-MYCN neuroblastoma tumors grow more aggressive and exhibit a distinct tumor microenvironment relative to their subcutaneous equivalents

scientific article published on 17 February 2015

MicroRNA genes preferentially expressed in dendritic cells contain sites for conserved transcription factor binding motifs in their promoters.

scientific article

Migration of dendritic cell based cancer vaccines: in vivo veritas?

scientific article

Molecular characterization of the murine homologue of the DC-derived protein DC-SCRIPT

scientific article

Multifaceted effects of synthetic TLR2 ligand and Legionella pneumophilia on Treg-mediated suppression of T cell activation

scientific article

NOD2 and toll-like receptors are nonredundant recognition systems of Mycobacterium tuberculosis

scientific article

Novel insights in the regulation of CCL18 secretion by monocytes and dendritic cells via cytokines, toll-like receptors and rheumatoid synovial fluid

scientific article published on 19 September 2006

OS9 interacts with DC-STAMP and modulates its intracellular localization in response to TLR ligation.

scientific article

Peptide fine specificity of anti-glycoprotein 100 CTL is preserved following transfer of engineered TCR alpha beta genes into primary human T lymphocytes

scientific article

Phagocytosis of enterovirus-infected pancreatic beta-cells triggers innate immune responses in human dendritic cells.

scientific article

Phenotypical and functional characterization of clinical-grade dendritic cells

scientific article

Platinum-based drugs disrupt STAT6-mediated suppression of immune responses against cancer in humans and mice

scientific article

Presence and localization of T-cell subsets in relation to melanocyte differentiation antigen expression and tumour regression as assessed by immunohistochemistry and molecular analysis of microdissected T cells.

scientific article

Prophylactic vaccines are potent activators of monocyte-derived dendritic cells and drive effective anti-tumor responses in melanoma patients at the cost of toxicity.

scientific article

Regulation of MYCN expression in human neuroblastoma cells.

scientific article published on 18 July 2009

Route of administration of the TLR9 agonist CpG critically determines the efficacy of cancer immunotherapy in mice

scientific article

Saponin-based adjuvant-induced dendritic cell cross-presentation is dependent on PERK activation

scientific article published on 09 April 2022

Saponin-based adjuvants induce cross-presentation in dendritic cells by intracellular lipid body formation

scientific article

Sialic acid blockade in dendritic cells enhances CD8<sup>+</sup> T cell responses by facilitating high-avidity interactions

scientific article published on 28 January 2022

Sialic acids sweeten a tumor's life

scientific article

Steering Siglec-Sialic Acid Interactions on Living Cells using Bioorthogonal Chemistry

scientific article published in 2017

Steering Siglec-Sialic Acid Interactions on Living Cells using Bioorthogonal Chemistry.

scientific article

TLR1/TLR2 Heterodimers Play an Important Role in the Recognition of Borrelia Spirochetes ⬇️

scientific article published on October 5, 2011

Targeting CD4(+) T-helper cells improves the induction of antitumor responses in dendritic cell-based vaccination

scientific article published on 18 October 2012

The Epstein-Barr Virus Glycoprotein gp150 Forms an Immune-Evasive Glycan Shield at the Surface of Infected Cells

scientific article

The dendritic cell-derived protein DC-STAMP is highly conserved and localizes to the endoplasmic reticulum

scientific article

The immunosuppressive tumour network: myeloid-derived suppressor cells, regulatory T cells and natural killer T cells

scientific article

The tetraspanin protein CD37 regulates IgA responses and anti-fungal immunity

scientific article

Thermal and mechanical high-intensity focused ultrasound: perspectives on tumor ablation, immune effects and combination strategies.

scientific article

Toll-like receptor 2 controls expansion and function of regulatory T cells

scientific article

Toll-like receptor expression and function in human dendritic cell subsets: implications for dendritic cell-based anti-cancer immunotherapy

scientific article published on 05 March 2010

Transcriptional and metabolic reprogramming induce an inflammatory phenotype in non-medullary thyroid carcinoma-induced macrophages.

scientific article published on 9 September 2016

Tumor ablation plus co-administration of CpG and saponin adjuvants affects IL-1 production and multifunctional T cell numbers in tumor draining lymph nodes

scientific article published on 01 May 2020

List of works by Gosse J Adema

An alternatively spliced CXCL16 isoform expressed by dendritic cells is a secreted chemoattractant for CXCR6+ cells

C-type lectin receptors on dendritic cells and Langerhans cells

Clinical significance of the nuclear receptor co-regulator DC-SCRIPT in breast cancer: an independent retrospective validation study.

Commonly used prophylactic vaccines as an alternative for synthetically produced TLR ligands to mature monocyte-derived dendritic cells

DC-SCRIPT is a novel regulator of the tumor suppressor gene CDKN2B and induces cell cycle arrest in ERα-positive breast cancer cells

DC-SCRIPT: nuclear receptor modulation and prognostic significance in primary breast cancer

DC-STAMP interacts with ER-resident transcription factor LUMAN which becomes activated during DC maturation

DC-STAMP knock-down deregulates cytokine production and T-cell stimulatory capacity of LPS-matured dendritic cells

Dectin-1 interaction with tetraspanin CD37 inhibits IL-6 production

Dendritic cells: tools and targets for antitumor vaccination

Development of a high-field MR-guided HIFU setup for thermal and mechanical ablation methods in small animals

Different faces of the heme-heme oxygenase system in inflammation

Differential Toll-like receptor recognition and induction of cytokine profile by Bifidobacterium breve and Lactobacillus strains of probiotics.

Differential expansion of circulating human MDSC subsets in patients with cancer, infection and inflammation

Differential expression regulation of the alpha and beta subunits of the PA28 proteasome activator in mature dendritic cells

Differential susceptibility and response of primary human myeloid BDCA1(+) dendritic cells to infection with different Enteroviruses

Enhanced lipid biosynthesis in human tumor-induced macrophages contributes to their protumoral characteristics

Enterovirus-infected β-cells induce distinct response patterns in BDCA1+ and BDCA3+ human dendritic cells

HDAC inhibitors and immunotherapy; a double edged sword?

Human TLR10 is an anti-inflammatory pattern-recognition receptor

Human dectin-1 deficiency and mucocutaneous fungal infections

Humoral anti-KLH responses in cancer patients treated with dendritic cell-based immunotherapy are dictated by different vaccination parameters ⬇️

Identification and characterization of DC-SCRIPT, a novel dendritic cell-expressed member of the zinc finger family of transcriptional regulators

Immune regulation by regulatory T cells: implications for transplantation

Immunotherapy and the Interventional Oncologist: Challenges and Opportunities-A Society of Interventional Oncology White Paper

In situ expression of tumor antigens by messenger RNA-electroporated dendritic cells in lymph nodes of melanoma patients

Interleukin-12 has no effect on vascular density, perfusion, hypoxia and proliferation of an implanted human squamous cell carcinoma xenograft tumour despite up-regulation of ICAM-1.

Intra-adrenal murine TH-MYCN neuroblastoma tumors grow more aggressive and exhibit a distinct tumor microenvironment relative to their subcutaneous equivalents

MicroRNA genes preferentially expressed in dendritic cells contain sites for conserved transcription factor binding motifs in their promoters.

Migration of dendritic cell based cancer vaccines: in vivo veritas?

Molecular characterization of the murine homologue of the DC-derived protein DC-SCRIPT

Multifaceted effects of synthetic TLR2 ligand and Legionella pneumophilia on Treg-mediated suppression of T cell activation

NOD2 and toll-like receptors are nonredundant recognition systems of Mycobacterium tuberculosis

Novel insights in the regulation of CCL18 secretion by monocytes and dendritic cells via cytokines, toll-like receptors and rheumatoid synovial fluid

OS9 interacts with DC-STAMP and modulates its intracellular localization in response to TLR ligation.

Peptide fine specificity of anti-glycoprotein 100 CTL is preserved following transfer of engineered TCR alpha beta genes into primary human T lymphocytes

Phagocytosis of enterovirus-infected pancreatic beta-cells triggers innate immune responses in human dendritic cells.

Phenotypical and functional characterization of clinical-grade dendritic cells

Platinum-based drugs disrupt STAT6-mediated suppression of immune responses against cancer in humans and mice

Presence and localization of T-cell subsets in relation to melanocyte differentiation antigen expression and tumour regression as assessed by immunohistochemistry and molecular analysis of microdissected T cells.

Prophylactic vaccines are potent activators of monocyte-derived dendritic cells and drive effective anti-tumor responses in melanoma patients at the cost of toxicity.

Regulation of MYCN expression in human neuroblastoma cells.

Route of administration of the TLR9 agonist CpG critically determines the efficacy of cancer immunotherapy in mice

Saponin-based adjuvant-induced dendritic cell cross-presentation is dependent on PERK activation

Saponin-based adjuvants induce cross-presentation in dendritic cells by intracellular lipid body formation

Sialic acid blockade in dendritic cells enhances CD8<sup>+</sup> T cell responses by facilitating high-avidity interactions

Sialic acids sweeten a tumor's life

Steering Siglec-Sialic Acid Interactions on Living Cells using Bioorthogonal Chemistry

Steering Siglec-Sialic Acid Interactions on Living Cells using Bioorthogonal Chemistry.

TLR1/TLR2 Heterodimers Play an Important Role in the Recognition of Borrelia Spirochetes ⬇️

Targeting CD4(+) T-helper cells improves the induction of antitumor responses in dendritic cell-based vaccination

The Epstein-Barr Virus Glycoprotein gp150 Forms an Immune-Evasive Glycan Shield at the Surface of Infected Cells

The dendritic cell-derived protein DC-STAMP is highly conserved and localizes to the endoplasmic reticulum

The immunosuppressive tumour network: myeloid-derived suppressor cells, regulatory T cells and natural killer T cells

The tetraspanin protein CD37 regulates IgA responses and anti-fungal immunity

Thermal and mechanical high-intensity focused ultrasound: perspectives on tumor ablation, immune effects and combination strategies.

Toll-like receptor 2 controls expansion and function of regulatory T cells

Toll-like receptor expression and function in human dendritic cell subsets: implications for dendritic cell-based anti-cancer immunotherapy

Transcriptional and metabolic reprogramming induce an inflammatory phenotype in non-medullary thyroid carcinoma-induced macrophages.

Tumor ablation plus co-administration of CpG and saponin adjuvants affects IL-1 production and multifunctional T cell numbers in tumor draining lymph nodes