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List of works by Kim J Hasenkrug

A functional subset of CD8 T cells during chronic exhaustion is defined by SIRPα expression

scientific article published in Nature Communications

A single nucleotide polymorphism in tetherin promotes retrovirus restriction in vivo

scientific article

Activated CD8+ T cells induce expansion of Vβ5+ regulatory T cells via TNFR2 signaling.

scientific article

Adaptive Immune Responses to Zika Virus Are Important for Controlling Virus Infection and Preventing Infection in Brain and Testes

scientific article (publication date: 22 March 2017)

Allogeneic lymphocytes persist and traffic in feral MHC-matched mauritian cynomolgus macaques

scientific article

An advanced BLT-humanized mouse model for extended HIV-1 cure studies.

scientific article

Antibodies Are Required for Complete Vaccine-Induced Protection against Herpes Simplex Virus 2.

scientific article published on 15 December 2015

Apobec3 encodes Rfv3, a gene influencing neutralizing antibody control of retrovirus infection

scientific article

B Cell Control of Regulatory T Cells in Friend Virus Infection

scientific article published on 26 June 2020

B Cell Requirement for Robust Regulatory T Cell Responses to Friend Retrovirus Infection

scientific article published on August 2017

B lymphocyte activation by coinfection prevents immune control of friend virus infection

scientific article published on September 2008

BLT-humanized C57BL/6 Rag2-/-γc-/-CD47-/- mice are resistant to GVHD and develop B- and T-cell immunity to HIV infection

scientific article published on 10 September 2013

CD137 costimulation of CD8+ T cells confers resistance to suppression by virus-induced regulatory T cells

scientific article published on April 2008

CD4+ T cells develop antiretroviral cytotoxic activity in the absence of regulatory T cells and CD8+ T cells

scientific article published on 27 March 2013

CD4+ regulatory T cells in chronic viral infection

scientific article published on January 1, 2003

CD8+ T cells are essential for controlling acute friend retrovirus infection in C57BL/6 mice

scientific article published on May 2014

CD8+ T-cell dysfunction due to cytolytic granule deficiency in persistent Friend retrovirus infection

scientific article

Clonotypic composition of the CD4+ T cell response to a vectored retroviral antigen is determined by its speed.

scientific article

Co-infection with the friend retrovirus and mouse scrapie does not alter prion disease pathogenesis in susceptible mice.

scientific article

Comment on "Premature terminal exhaustion of Friend virus-specific effector CD8+ T cells by rapid induction of multiple inhibitory receptors".

scientific article published in August 2010

Complement as an endogenous adjuvant for dendritic cell-mediated induction of retrovirus-specific CTLs.

scientific article

Complement opsonization enhances friend virus infection of B cells and thereby amplifies the virus-specific CD8+ T cell response

scientific article published on 3 November 2010

Concurrent administration of IFNα14 and cART in TKO-BLT mice enhances suppression of HIV-1 viremia but does not eliminate the latent reservoir

scientific article published on 02 December 2019

Correction: Co-Infection with the Friend Retrovirus and Mouse Scrapie Does Not Alter Prion Disease Pathogenesis in Susceptible Mice

scientific article published on 12 June 2012

Different Biological Activities of Specific Interferon Alpha Subtypes

scientific article published on 24 July 2019

Distinct roles of CD4+ T cell subpopulations in retroviral immunity: lessons from the Friend virus mouse model

scientific article

Diversity of murine norovirus strains isolated from asymptomatic mice of different genetic backgrounds within a single U.S. research institute

scientific article

Ebola Virus Replication and Disease Without Immunopathology in Mice Expressing Transgenes to Support Human Myeloid and Lymphoid Cell Engraftment

scientific article published on 6 September 2016

Effective treatment of retrovirus-induced suppression of antibody responses with CpG oligodeoxynucleotides

scientific article published on 01 December 2005

Effects of Friend Virus Infection and Regulatory T Cells on the Antigen Presentation Function of B Cells

scientific article published on 22 January 2019

Effects of acute and chronic murine norovirus infections on immune responses and recovery from Friend retrovirus infection

scientific article published on 07 October 2009

Essential role for virus-neutralizing antibodies in sterilizing immunity against Friend retrovirus infection

scholarly article

Essential roles for CD8+ T cells and gamma interferon in protection of mice against retrovirus-induced immunosuppression

scientific article

Fas Ligand-mediated cytotoxicity of CD4+ T cells during chronic retrovirus infection.

scientific article published on 10 August 2017

Friend retrovirus studies reveal complex interactions between intrinsic, innate and adaptive immunity

scientific article published on 01 September 2019

Functional impairment of CD8(+) T cells by regulatory T cells during persistent retroviral infection

scientific article published in March 2004

HIV vaccine design: insights from live attenuated SIV vaccines

scientific article

IFN-α treatment inhibits acute Friend retrovirus replication primarily through the antiviral effector molecule Apobec3.

scientific article published on 11 January 2013

IL-2-independent and TNF-α-dependent expansion of Vβ5+ natural regulatory T cells during retrovirus infection

scientific article published on 03 May 2013

Immune control and prevention of chronic Friend retrovirus infection

scientific article published on January 2007

Immunoglobulin somatic hypermutation by APOBEC3/Rfv3 during retroviral infection

scientific article

Immunotherapeutic Blockade of CD47 Inhibitory Signaling Enhances Innate and Adaptive Immune Responses to Viral Infection

scientific article published on 01 April 2020

Improvements and Limitations of Humanized Mouse Models for HIV Research: NIH/NIAID "Meet the Experts" 2015 Workshop Summary

scientific article published on 16 December 2015

In Vitro and In Vivo Analyses of Regulatory T Cell Suppression of CD8+ T Cells ⬇️

scientific article published on January 1, 2011

In vitro suppression of CD8+ T cell function by Friend virus-induced regulatory T cells

scientific article published in March 2006

In vivo interactions of ecotropic and polytropic murine leukemia viruses in mixed retrovirus infections

scientific article

Innate retroviral restriction by Apobec3 promotes antibody affinity maturation in vivo

scientific article

Interferon Alpha Subtype-Specific Suppression of HIV-1 Infection In Vivo

scientific article published on 20 April 2016

Interferon-α Subtypes in an Ex Vivo Model of Acute HIV-1 Infection: Expression, Potency and Effector Mechanisms

scientific article published on 3 November 2015

Lactate dehydrogenase-elevating virus induces systemic lymphocyte activation via TLR7-dependent IFNalpha responses by plasmacytoid dendritic cells

scientific article

Mice of the resistant H-2(b) haplotype mount broad CD4(+) T cell responses against 9 distinct Friend virus epitopes

scientific article

Mouse APOBEC3 expression in NIH 3T3 cells mediates hypermutation of AKV murine leukemia virus.

scientific article

Negative impact of IFN-γ on early host immune responses to retroviral infection.

scientific article

No SEVI-mediated enhancement of rectal HIV-1 transmission of HIV-1 in two humanized mouse cohorts

scientific article published on 20 November 2015

Noninfectious retrovirus particles drive the APOBEC3/Rfv3 dependent neutralizing antibody response

scientific article

Novel role of CD8(+) T cells and major histocompatibility complex class I genes in the generation of protective CD4(+) Th1 responses during retrovirus infection in mice

scientific article

Pathogenicity of Ebola and Marburg Viruses Is Associated With Differential Activation of the Myeloid Compartment in Humanized Triple Knockout-Bone Marrow, Liver, and Thymus Mice

scholarly article by Kerry J Lavender et al published 22 November 2018 in Journal of Infectious Diseases

Persistent Friend virus replication and disease in Apobec3-deficient mice expressing functional B-cell-activating factor receptor

scientific article

Production of bone marrow, liver, thymus (BLT) humanized mice on the C57BL/6 Rag2(-/-)γc(-/-)CD47(-/-) background

scientific article

Qualitative Differences Between the IFNα subtypes and IFNβ Influence Chronic Mucosal HIV-1 Pathogenesis

scientific article published on 16 October 2020

Race between retroviral spread and CD4+ T-cell response determines the outcome of acute Friend virus infection

scientific article published on 19 August 2009

Reduction of retrovirus-induced immunosuppression by in vivo modulation of T cells during acute infection

scientific article

Regulatory T cells in retroviral infections

scientific article published on 15 February 2018

Regulatory T cells suppress virus-specific antibody responses to Friend retrovirus infection.

scientific article

Retroviral immunology: lessons from a mouse model

scientific article published on January 2009

Retrovirus-specificity of regulatory T cells is neither present nor required in preventing retrovirus-induced bone marrow immune pathology

scientific article

Serial infection of diverse host (Mus) genotypes rapidly impedes pathogen fitness and virulence

scientific article published in January 2015

Stimulation of Toll-Like Receptors profoundly influences the titer of polyreactive antibodies in the circulation

scientific article

Suppression of acute anti-friend virus CD8+ T-cell responses by coinfection with lactate dehydrogenase-elevating virus

scientific article

Temporal effects of gamma interferon deficiency on the course of Friend retrovirus infection in mice

scientific article

Tetherin promotes the innate and adaptive cell-mediated immune response against retrovirus infection in vivo.

scientific article

Tetherin/BST-2 promotes dendritic cell activation and function during acute retrovirus infection.

scientific article published on 5 February 2016

The glycosylated Gag protein of a murine leukemia virus inhibits the antiretroviral function of APOBEC3.

scientific article

The leptin connection: regulatory T cells and autoimmunity

scientific article published on February 2007

The role of virus-induced regulatory T cells in immunopathology

scientific article published on 14 July 2006

Tissue-specific abundance of regulatory T cells correlates with CD8+ T cell dysfunction and chronic retrovirus loads

scientific article published on 08 July 2009

Transient depletion of regulatory T cells in transgenic mice reactivates virus-specific CD8 + T cells and reduces chronic retroviral set points ⬇️

scientific article published on January 24, 2011

Type I interferon signaling is required for the APOBEC3/Rfv3-dependent neutralizing antibody response but not innate retrovirus restriction

scientific article

Upregulation of CD47 Is a Host Checkpoint Response to Pathogen Recognition

scientific article published on 23 June 2020

Virus-Specific CD8+ T Cells Upregulate Programmed Death-1 Expression during Acute Friend Retrovirus Infection but Are Highly Cytotoxic and Control Virus Replication ⬇️

scientific article published on August 26, 2011

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