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List of works by Sha Mi

Assessment of functional recovery and axonal sprouting in oligodendrocyte-myelin glycoprotein (OMgp) null mice after spinal cord injury

scientific journal article

Blocking LINGO-1 function promotes retinal ganglion cell survival following ocular hypertension and optic nerve transection.

scientific article

Blocking LINGO-1 in vivo reduces degeneration and enhances regeneration of the optic nerve

scientific article

Characterization of trisulfide modification in antibodies

scientific article published on 18 January 2010

Death receptor 6 negatively regulates oligodendrocyte survival, maturation and myelination ⬇️

scientific article published on July 3, 2011

Disulfide structure of the leucine-rich repeat C-terminal cap and C-terminal stalk region of Nogo-66 receptor

scientific article

Exposure Levels of Anti-LINGO-1 Li81 Antibody in the Central Nervous System and Dose-Efficacy Relationships in Rat Spinal Cord Remyelination Models after Systemic Administration ⬇️

scientific article published on August 1, 2011

Functional activity of anti-LINGO-1 antibody opicinumab requires target engagement at a secondary binding site

scientific article published on 01 January 2020

Improving the solubility of anti-LINGO-1 monoclonal antibody Li33 by isotype switching and targeted mutagenesis

scientific article

Inhibition of LINGO-1 promotes functional recovery after experimental spinal cord demyelination

scientific article published on 11 February 2015

Inhibition of the leucine-rich repeat protein LINGO-1 enhances survival, structure, and function of dopaminergic neurons in Parkinson's disease models

scientific article

LINGO-1 Regulates Oligodendrocyte Differentiation through the Cytoplasmic Gelsolin Signaling Pathway.

scientific article published on 13 February 2017

LINGO-1 antagonist promotes functional recovery and axonal sprouting after spinal cord injury

scientific article published on 29 September 2006

LINGO-1 antagonist promotes spinal cord remyelination and axonal integrity in MOG-induced experimental autoimmune encephalomyelitis

scientific article published on 30 September 2007

LINGO-1 is a component of the Nogo-66 receptor/p75 signaling complex

scientific article

LINGO-1 negatively regulates TrkB phosphorylation after ocular hypertension.

scientific article published on March 2010

LINGO-1 negatively regulates myelination by oligodendrocytes

scientific journal article

LINGO-1 regulates oligodendrocyte differentiation by inhibiting ErbB2 translocation and activation in lipid rafts

scientific article published on 28 February 2014

NGF regulates the expression of axonal LINGO-1 to inhibit oligodendrocyte differentiation and myelination

scientific article published on 01 January 2007

Oligodendrocyte differentiation and myelination defects in OMgp null mice ⬇️

scientific article published on February 23, 2011

Production of a PEGylated Fab′ of the anti-LINGO-1 Li33 Antibody and Assessment of Its Biochemical and Functional Properties in Vitro and in a Rat Model of Remyelination ⬇️

scientific article published on January 21, 2011

Promotion of central nervous system remyelination by induced differentiation of oligodendrocyte precursor cells

scientific article (publication date: March 2009)

Role of transmembrane semaphorin Sema6A in oligodendrocyte differentiation and myelination.

scientific article published on 9 July 2012

Sphingosine 1-phosphate receptor modulator fingolimod (FTY720) does not promote remyelination in vivo ⬇️

scientific article published on June 24, 2011

Structure of the LINGO-1-anti-LINGO-1 Li81 antibody complex provides insights into the biology of LINGO-1 and the mechanism of action of the antibody therapy

scientific article

TAJ/TROY, an orphan TNF receptor family member, binds Nogo-66 receptor 1 and regulates axonal regeneration

scientific article

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