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List of works by Benjamin Meder

A blood based 12-miRNA signature of Alzheimer disease patients

scientific article

A genome-wide association study identifies 6p21 as novel risk locus for dilated cardiomyopathy

scientific article published on 12 July 2013

A high-resolution map of the human small non-coding transcriptome

scientific article

A mutation in the glutamate-rich region of RNA-binding motif protein 20 causes dilated cardiomyopathy through missplicing of titin and impaired Frank-Starling mechanism.

scientific article published on 5 August 2016

A proteolytic fragment of histone deacetylase 4 protects the heart from failure by regulating the hexosamine biosynthetic pathway.

scientific article published on 11 December 2017

A self-taught artificial agent for multi-physics computational model personalization.

scientific article

A single serine in the carboxyl terminus of cardiac essential myosin light chain-1 controls cardiomyocyte contractility in vivo

scientific article published on 22 January 2009

ANK2 functionally interacts with KCNH2 aggravating long QT syndrome in a double mutation carrier

scientific article published on 28 March 2019

Age-Related Variations in Takotsubo Syndrome

scientific article published on 01 April 2020

Alterations in cardiac DNA methylation in human dilated cardiomyopathy

scientific article

Arteriogenesis depends on circulating monocytes and macrophage accumulation and is severely depressed in op/op mice

scientific article published on 09 May 2006

Aspirin, but not clopidogrel, reduces collateral conductance in a rabbit model of femoral artery occlusion

scientific article (publication date: 20 September 2005)

Assessment of myocardial deformation with cardiac magnetic resonance strain imaging improves risk stratification in patients with dilated cardiomyopathy

scientific article published on 21 September 2014

Atlas of the clinical genetics of human dilated cardiomyopathy

scientific article (publication date: 7 May 2015)

BALL-SNP: combining genetic and structural information to identify candidate non-synonymous single nucleotide polymorphisms.

scientific article published on July 2015

Bias in High-Throughput Analysis of miRNAs and Implications for Biomarker Studies

scientific article

Biomarker changes after strenuous exercise can mimic pulmonary embolism and cardiac injury--a metaanalysis of 45 studies

scientific article published on 03 August 2015

CD26 Inhibition Enhances Perfusion Recovery in ApoE-/-Mice

scientific article published on 01 January 2013

Catecholamine-Dependent β-Adrenergic Signaling in a Pluripotent Stem Cell Model of Takotsubo Cardiomyopathy

scientific article published in August 2017

Clinical and Genetic Investigations of 109 Index Patients With Dilated Cardiomyopathy and 445 of Their Relatives

scientific article published on 06 October 2020

Clinical and genetic insights into non-compaction: a meta-analysis and systematic review on 7598 individuals

scientific article published on 12 April 2019

Clinical genetics and outcome of left ventricular non-compaction cardiomyopathy

scientific article

Clinical outcomes associated with sarcomere mutations in hypertrophic cardiomyopathy: a meta-analysis on 7675 individuals

scientific article

Common diseases alter the physiological age-related blood microRNA profile

scientific article published on 24 November 2020

Complex roads from genotype to phenotype in dilated cardiomyopathy: scientific update from the Working Group of Myocardial Function of the European Society of Cardiology

scientific article published on 01 August 2018

Comprehensive analysis of microRNA profiles in multiple sclerosis including next-generation sequencing

scientific article

Computational Cardiology - A New Discipline of Translational Research

scientific article published on 3 August 2016

Data-driven estimation of cardiac electrical diffusivity from 12-lead ECG signals.

scientific article

Deep Characterization of Circular RNAs from Human Cardiovascular Cell Models and Cardiac Tissue

scientific article published on 04 July 2020

Deep characterization of blood cell miRNomes by NGS

scientific article published on 13 February 2016

Deficient zebrafish ether-à-go-go-related gene channel gating causes short-QT syndrome in zebrafish reggae mutants.

scientific article published on 4 February 2008

Determined to Fail--the Role of Genetic Mechanisms in Heart Failure

scientific article published on 02 August 2015

Distribution of miRNA expression across human tissues

scientific article

Double-Stranded Ligation Assay for the Rapid Multiplex Quantification of MicroRNAs

scientific article published on 17 November 2015

Dual Functional States of R406W-Desmin Assembly Complexes Cause Cardiomyopathy With Severe Intercalated Disc Derangement in Humans and in Knock-In Mice

scientific article published on 07 October 2020

Effects of β-blocker therapy on electrocardiographic and echocardiographic characteristics of left ventricular noncompaction

scientific article published on 21 October 2014

Epigenetic Regulation of Alternative mRNA Splicing in Dilated Cardiomyopathy

scientific article published on 16 May 2020

Epigenome-Wide Association Study Identifies Cardiac Gene Patterning and a Novel Class of Biomarkers for Heart Failure

scientific article published on 24 August 2017

Erratum to: miRNAs and sports: tracking training status and potentially confounding diagnoses

scientific article published on 13 October 2016

Essential light chain S195 phosphorylation is required for cardiac adaptation under physical stress

scientific article published on 24 March 2016

Evaluating the Use of Circulating MicroRNA Profiles for Lung Cancer Detection in Symptomatic Patients

scientific article published on 05 March 2020

Familial Recurrent Myocarditis Triggered by Exercise in Patients With a Truncating Variant of the Desmoplakin Gene

scientific article published on 15 May 2020

Fast data-driven calibration of a cardiac electrophysiology model from images and ECG

scientific article published on 01 January 2013

From Single Variants to Protein Cascades: MULTISCALE MODELING OF SINGLE NUCLEOTIDE VARIANT SETS IN GENETIC DISORDERS.

scientific article published on 24 November 2015

Generation of pluripotent stem cell lines and CRISPR/Cas9 modified isogenic controls from a patient with dilated cardiomyopathy harboring a RBM20 p.R634W mutation

scientific article published on 02 July 2020

Genetic Reduction in Left Ventricular Protein Kinase C-α and Adverse Ventricular Remodeling in Human Subjects

Genomic structural variations lead to dysregulation of important coding and non-coding RNA species in dilated cardiomyopathy.

scientific article

Genotype-phenotype associations in dilated cardiomyopathy: meta-analysis on more than 8000 individuals

scientific article

HBEGF, SRA1, and IK: Three cosegregating genes as determinants of cardiomyopathy

scientific article published on 08 December 2008

Heart-Specific Immune Responses in an Animal Model of AutoimmuneRelated Myocarditis Mitigated by an Immunoproteasome Inhibitor and Genetic Ablation

scientific article published on 12 March 2020

Identification and Functional Characterization of Hypoxia-Induced Endoplasmic Reticulum Stress Regulating lncRNA (HypERlnc) in Pericytes

scientific article published on 13 June 2017

Identification and regulation of the long non-coding RNA Heat2 in heart failure

scientific article published on 13 November 2018

Identification of Novel SNPs in Glioblastoma Using Targeted Resequencing ⬇️

scientific article published on June 10, 2011

Immune system-mediated atherosclerosis caused by deficiency of long noncoding RNA MALAT1 in ApoE-/- mice

scientific article published on 01 February 2019

Improvements of Procedural Results With a New-Generation Self-Expanding Transfemoral Aortic Valve Prosthesis in Comparison to the Old-Generation Device

scientific article published on 24 November 2016

In-vivo characterization of human dilated cardiomyopathy genes in zebrafish

scientific article published on 2 October 2009

Influence of next-generation sequencing and storage conditions on miRNA patterns generated from PAXgene blood.

scientific article

Influence of the confounding factors age and sex on microRNA profiles from peripheral blood

scientific article published on 30 June 2014

Initial Single-Center Experience With the Fully Repositionable Transfemoral Lotus Aortic Valve System

scientific article published on 15 November 2016

Involvement of BAG3 and HSPB7 loci in various etiologies of systolic heart failure: Results of a European collaboration assembling more than 2000 patients

scientific article published in April 2015

JunB-CBFbeta signaling is essential to maintain sarcomeric Z-disc structure and when defective leads to heart failure.

scientific article published on 6 July 2010

Left Ventricular Biopsy in the Diagnosis of Myocardial Diseases

scientific article published on 01 March 2018

Left ventricular long axis strain: a new prognosticator in non-ischemic dilated cardiomyopathy?

scientific article published on 7 June 2016

Long noncoding RNA MALAT1-derived mascRNA is involved in cardiovascular innate immunity.

scientific article published on 27 January 2016

Long noncoding RNA NEAT1 modulates immune cell functions and is suppressed in early onset myocardial infarction patients

scientific article published on 01 November 2019

Machine learning-based risk prediction of intrahospital clinical outcomes in patients undergoing TAVI

scientific article published on 24 June 2020

Mavacamten Favorably Impacts Cardiac Structure in Obstructive Hypertrophic Cardiomyopathy: EXPLORER-HCM CMR Substudy Analysis

scientific article published on 15 November 2020

MiRTargetLink--miRNAs, Genes and Interaction Networks

scientific article published on 14 April 2016

MicroRNA in vitro diagnostics using immunoassay analyzers

scientific article published on 23 January 2015

MicroRNA signatures in total peripheral blood as novel biomarkers for acute myocardial infarction ⬇️

scientific article published on October 1, 2010

Multi-omics assessment of dilated cardiomyopathy using non-negative matrix factorization

scientific article published in 2022

Multivariate miRNA signatures as biomarkers for non-ischaemic systolic heart failure ⬇️

scientific article published on July 17, 2013

Natural genetic variation of the cardiac transcriptome in non-diseased donors and patients with dilated cardiomyopathy.

scientific article published on 14 September 2017

New insights into the Tyrolean Iceman's origin and phenotype as inferred by whole-genome sequencing

scientific article

New insights into the genetics of glioblastoma multiforme by familial exome sequencing.

scientific article published on March 2015

Nexilin mutations destabilize cardiac Z-disks and lead to dilated cardiomyopathy

scientific article

Next-generation sequencing entering the clinical arena

scientific article published on 8 September 2011

Next-generation sequencing identifies altered whole blood microRNAs in neuromyelitis optica spectrum disorder which may permit discrimination from multiple sclerosis

scientific article published on 31 October 2015

Next-generation sequencing identifies novel microRNAs in peripheral blood of lung cancer patients ⬇️

scientific article published on October 25, 2011

Next-generation sequencing: from understanding biology to personalized medicine

scientific article

Non-coding RNAs in cardiovascular diseases: diagnostic and therapeutic perspectives.

scientific article published on 18 April 2017

Nucleoside Diphosphate Kinase-C Suppresses cAMP Formation in Human Heart Failure.

scientific article published on 07 December 2016

PINCH proteins regulate cardiac contractility by modulating integrin-linked kinase-protein kinase B signaling.

scientific article

Paleoproteomic study of the Iceman's brain tissue.

scientific article

Pathogenicity prediction of non-synonymous single nucleotide variants in dilated cardiomyopathy

scientific article published on 30 January 2015

Pathophysiological background and prognostic implication of systolic aortic root motion in non-ischemic dilated cardiomyopathy

scientific article published on 07 March 2019

Pathway-based variant enrichment analysis on the example of dilated cardiomyopathy.

scientific article published on 7 November 2015

Periprocedural antibiotic treatment in transvascular aortic valve replacement

scientific article published on 05 November 2018

Personalized Computer Simulation of Diastolic Function in Heart Failure.

scientific article published on 28 July 2016

Post cardiac injury syndrome after initially uncomplicated CRT-D implantation: a case report and a systematic review

scientific article published on 29 April 2014

Postcardiac injury syndrome after cardiac implantable electronic device implantation

scientific article published on 13 March 2020

Predicting sustained ventricular arrhythmias in dilated cardiomyopathy: a meta-analysis and systematic review

scientific article published on 14 April 2020

Prevalence and relevance of impaired left ventricular function in chronic moderate regurgitation of native aortic valves

scientific article published on 16 July 2019

Prioritizing and selecting likely novel miRNAs from NGS data.

scientific article published on 3 December 2015

Prognostic value of myocardial strain analysis with cardiac magnetic resonance in patients with dilated cardiomyopathy.

scientific article published on 16 January 2014

Protein Kinase D2 Controls Cardiac Valve Formation in Zebrafish by Regulating Histone Deacetylase 5 Activity ⬇️

scientific article published on July 5, 2011

Pulmonary vein isolation treats symptomatic AF in a patient with Lamin A/C mutation: case report and review of the literature

scientific article published on 06 March 2020

Quantification of collateral artery growth by automated fluorescent microsphere perfusion ⬇️

scientific article published on May 23, 2011

Quantitative Expression of the Mutated Lamin A/C Gene in Patients With Cardiolaminopathy

article

RNA splicing regulated by RBFOX1 is essential for cardiac function in zebrafish

scientific article

Reconstitution of defective protein trafficking rescues Long-QT syndrome in zebrafish ⬇️

scientific article published on March 31, 2011

Refining Diagnostic MicroRNA Signatures by Whole-miRNome Kinetic Analysis in Acute Myocardial Infarction ⬇️

scientific article published on December 19, 2012

Renal sympathetic denervation therapy in the real world: results from the Heidelberg registry

scientific article

Right into the heart of microRNA-133a

scientific article

Robust image-based estimation of cardiac tissue parameters and their uncertainty from noisy data

scientific article published on 01 January 2014

SLM2 Is A Novel Cardiac Splicing Factor Involved in Heart Failure due to Dilated Cardiomyopathy

scientific article published in 2022

Severe DCM phenotype of patient harboring RBM20 mutation S635A can be modeled by patient-specific induced pluripotent stem cell-derived cardiomyocytes

scientific article

Silencing of CCR2 in myocarditis

scientific article published on 20 June 2014

Silencing the CSF-1 Axis Using Nanoparticle Encapsulated siRNA Mitigates Viral and Autoimmune Myocarditis

Sudden cardiac death in a patient with lamin A/C mutation in the absence of dilated cardiomyopathy or conduction disease ⬇️

scientific article published on February 16, 2011

Systematic permutation testing in GWAS pathway analyses: identification of genetic networks in dilated cardiomyopathy and ulcerative colitis.

scientific article

Targeted Next-Generation Sequencing for the Molecular Genetic Diagnostics of Cardiomyopathies ⬇️

scientific article published on January 20, 2011

Targeted next-generation sequencing: the clinician's stethoscope for genetic disorders

scientific article published on 01 August 2014

The C-terminal HCN4 variant P883R alters channel properties and acts as genetic modifier of atrial fibrillation and structural heart disease

scientific article published on 31 August 2019

The Role of Quality Control in Targeted Next-generation Sequencing Library Preparation

scientific article

The chameleon of cardiology: cardiac sarcoidosis before and after heart transplantation

scientific article published on 05 December 2019

The current role of next-generation DNA sequencing in routine care of patients with hereditary cardiovascular conditions: a viewpoint paper of the European Society of Cardiology working group on myocardial and pericardial diseases and members of the

scientific article published on 05 April 2015

The human miRNA repertoire of different blood compounds

scientific article

The myosin-interacting protein SMYD1 is essential for sarcomere organization ⬇️

scientific article published on August 18, 2011

The prognostic value of right ventricular long axis strain in non-ischaemic dilated cardiomyopathies using standard cardiac magnetic resonance imaging

scientific article published on 10 February 2017

The symptom complex of familial sinus node dysfunction and myocardial noncompaction is associated with mutations in the HCN4 channel.

scientific article

Toward the blood-borne miRNome of human diseases.

scientific article

Towards Personalized Cardiology: Multi-Scale Modeling of the Failing Heart.

scientific article published on 31 July 2015

TranslatiOnal Registry for CardiomyopatHies (TORCH) - rationale and first results

scientific article published on 14 March 2017

Unidimensional Longitudinal Strain: A Simple Approach for the Assessment of Longitudinal Myocardial Deformation by Echocardiography

scientific article published on 2 February 2018

Validating Alzheimer's disease micro RNAs using next-generation sequencing

scientific article published on 21 January 2016

Web-based NGS data analysis using miRMaster: a large-scale meta-analysis of human miRNAs

scientific article published on September 2017

Whole miRNome-Wide Differential Co-Expression of MicroRNAs ⬇️

scientific article published on August 23, 2012

iPSC Modeling of RBM20-Deficient DCM Identifies Upregulation of RBM20 as a Therapeutic Strategy

scientific article published on 01 September 2020

miFRame: analysis and visualization of miRNA sequencing data in neurological disorders

scientific article published on 14 July 2015

miRNAs and sports: tracking training status and potentially confounding diagnoses

scientific article published on 26 July 2016

miRNAs can be generally associated with human pathologies as exemplified for miR-144.

scientific article

miRNAs in Ancient Tissue Specimens of the Tyrolean Iceman.

scientific article published on 26 December 2016

miRTrail--a comprehensive webserver for analyzing gene and miRNA patterns to enhance the understanding of regulatory mechanisms in diseases.

scientific article

microRNA neural networks improve diagnosis of acute coronary syndrome (ACS)

scientific article published on 16 April 2020

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