List of works by Lori A Knackstedt

A Rat Model of Cocaine-Alcohol Polysubstance Use Reveals Altered Cocaine Seeking and Glutamate Levels in the Nucleus Accumbens

scientific article published on 18 August 2020

A novel rat model of comorbid PTSD and addiction reveals intersections between stress susceptibility and enhanced cocaine seeking with a role for mGlu5 receptors

scientific article published on 05 October 2018

Addicted to palatable foods: comparing the neurobiology of Bulimia Nervosa to that of drug addiction

scientific article

Alcohol consumption increases basal extracellular glutamate in the nucleus accumbens core of Sprague-Dawley rats without increasing spontaneous glutamate release.

scientific article published on 21 May 2016

Animal models and brain circuits in drug addiction

scientific article published on December 2006

Ceftriaxone and cefazolin attenuate the cue-primed reinstatement of alcohol-seeking

scientific article

Ceftriaxone and mGlu2/3 interactions in the nucleus accumbens core affect the reinstatement of cocaine-seeking in male and female rats

scientific article published on 07 May 2020

Ceftriaxone attenuates cocaine relapse after abstinence through modulation of nucleus accumbens AMPA subunit expression

scientific article published on 10 December 2015

Ceftriaxone normalizes nucleus accumbens synaptic transmission, glutamate transport, and export following cocaine self-administration and extinction training

scientific article

Ceftriaxone prevents the induction of cocaine sensitization and produces enduring attenuation of cue- and cocaine-primed reinstatement of cocaine-seeking

scientific article

Ceftriaxone reduces alcohol intake in outbred rats while upregulating xCT in the nucleus accumbens core.

scientific article published on 4 July 2017

Ceftriaxone restores glutamate homeostasis and prevents relapse to cocaine seeking

scientific article

Cocaine use disorder: A look at metabotropic glutamate receptors and glutamate transporters

scientific article published on 22 December 2020

Cocaine-induced adaptations in cellular redox balance contributes to enduring behavioral plasticity

scientific article

Conditioned stress prevents cue-primed cocaine reinstatement only in stress-responsive rats

scientific article published on 16 May 2016

Contrasting the Role of xCT and GLT-1 Upregulation in the Ability of Ceftriaxone to Attenuate the Cue-Induced Reinstatement of Cocaine Seeking and Normalize AMPA Receptor Subunit Expression.

scientific article published on 11 May 2017

Dose-dependent reduction in cocaine-induced locomotion by Clozapine-N-Oxide in rats with a history of cocaine self-administration.

scientific article published on 20 March 2018

Evidence for opponent-process actions of intravenous cocaine and cocaethylene

scientific article

Extended access to cocaine self-administration enhances drug-primed reinstatement but not behavioral sensitization

scientific article

Extinction training after cocaine self-administration induces glutamatergic plasticity to inhibit cocaine seeking

scientific article

Glutamate and reinstatement

scientific article published on 20 January 2009

Glutamate homeostasis and dopamine signaling: implications for psychostimulant addiction behavior

scientific article published on 04 November 2020

Glutamate transmission in addiction

scientific article published on 16 July 2008

Glutamate transporter GLT-1 mediates N-acetylcysteine inhibition of cocaine reinstatement

scientific article published on 25 February 2014

Hypothalamic-pituitary-adrenal axis activity in post-traumatic stress disorder and cocaine use disorder

scientific article published on 24 August 2020

Impairments in reversal learning following short access to cocaine self-administration

scientific article published on 25 September 2018

Increased mGlu5 mRNA expression in BLA glutamate neurons facilitates resilience to the long-term effects of a single predator scent stress exposure

scientific article published in 2021

Main path and byways: non-vesicular glutamate release by system xc(-) as an important modifier of glutamatergic neurotransmission

scientific article published on 04 September 2015

Molecular changes evoked by the beta-lactam antibiotic ceftriaxone across rodent models of substance use disorder and neurological disease

scientific article published on 30 May 2020

Nucleus accumbens GLT-1a overexpression reduces glutamate efflux during reinstatement of cocaine-seeking but is not sufficient to attenuate reinstatement.

scientific article published on 19 March 2018

Regionally Specific Effects of Oxytocin on Reinstatement of Cocaine Seeking in Male and Female Rats.

scientific article published in July 2018

Repeated cycles of chronic intermittent ethanol exposure increases basal glutamate in the nucleus accumbens of mice without affecting glutamate transport

scientific article

Resilience to Anxiety and Anhedonia after Predator Scent Stress is Accompanied by Increased Nucleus Accumbens mGlu5 in Female Rats

scientific article published on 26 April 2022

Role of mGluR5 neurotransmission in reinstated cocaine-seeking

scientific article

Role of prefrontal cortex projections to the nucleus accumbens core in mediating the effects of ceftriaxone on cue-induced cocaine seeking

scientific article published on 18 June 2020

Sequential cocaine-alcohol self-administration produces adaptations in rat nucleus accumbens core glutamate homeostasis that are distinct from those produced by cocaine self-administration alone

scientific article published on 02 July 2019

The Divergent Effects of CDPPB and Cannabidiol on Fear Extinction and Anxiety in a Predator Scent Stress Model of PTSD in Rats

article by John Shallcross et al published 2019 in Frontiers in Behavioral Neuroscience

The effects of Pavlovian cue extinction and ceftriaxone on cocaine relapse after abstinence.

scientific article published on 13 February 2019

The effects of ceftriaxone on cue-primed reinstatement of cocaine-seeking in male and female rats: estrous cycle effects on behavior and protein expression in the nucleus accumbens

scientific article published on 2 December 2017

The effects of clavulanic acid and amoxicillin on cue-primed reinstatement of cocaine seeking

scientific article published on 04 February 2019

The importance of considering polysubstance use: lessons from cocaine research

scientific article published on 01 September 2018

The role of cystine-glutamate exchange in nicotine dependence in rats and humans

scientific journal article

The role of ventral and dorsal striatum mGluR5 in relapse to cocaine-seeking and extinction learning

scientific article published on 27 May 2013

mGlu5 Receptors and Relapse to Cocaine-Seeking: The Role of Receptor Trafficking in Postrelapse Extinction Learning Deficits

scientific article published on 10 January 2016

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