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List of works by Charlotte Kuperwasser

A mouse model of human breast cancer metastasis to human bone

scientific article published on July 2005

A novel lung metastasis signature links Wnt signaling with cancer cell self-renewal and epithelial-mesenchymal transition in basal-like breast cancer

scientific article

Alterations of the HBP1 transcriptional repressor are associated with invasive breast cancer

scientific article published on July 2007

Anatomical localization of progenitor cells in human breast tissue reveals enrichment of uncommitted cells within immature lobules

scientific article

Assessment of the role of circulating breast cancer cells in tumor formation and metastatic potential using in vivo flow cytometry ⬇️

scientific article published on April 1, 2011

Automated quantification of three-dimensional organization of fiber-like structures in biological tissues

scientific article published on 25 November 2016

BCL11B Drives Human Mammary Stem Cell Self-Renewal In Vitro by Inhibiting Basal Differentiation

scientific article published on 22 February 2018

BRCA1-hapoinsufficiency: Unraveling the molecular and cellular basis for tissue-specific cancer

scientific article published on 29 January 2016

Breast tissue regeneration is driven by cell-matrix interactions coordinating multi-lineage stem cell differentiation through DDR1

scientific article published on 10 December 2021

Cell Fate Decisions During Breast Cancer Development

scientific article published on 22 January 2016

Cell-state transitions regulated by SLUG are critical for tissue regeneration and tumor initiation

scientific article

CoREST1 promotes tumor formation and tumor stroma interactions in a mouse model of breast cancer

scientific article

Contributions of estrogen to ER-negative breast tumor growth

scientific article published on 16 October 2006

Cyclin D1 Activity Regulates Autophagy and Senescence in the Mammary Epithelium ⬇️

scientific article published on October 4, 2012

Cyclin D1 kinase activity is required for the self-renewal of mammary stem and progenitor cells that are targets of MMTV-ErbB2 tumorigenesis

scientific article

Defining the cellular precursors to human breast cancer

scientific article published on 21 September 2011

Dissecting genetic requirements of human breast tumorigenesis in a tissue transgenic model of human breast cancer in mice.

scholarly article

Distinct roles of the three Akt isoforms in lactogenic differentiation and involution

scientific article

Endothelial Akt signaling is rate-limiting for rapamycin inhibition of mouse mammary tumor progression

scientific article published on June 2007

Epigenetic Reprogramming of Lineage-Committed Human Mammary Epithelial Cells Requires DNMT3A and Loss of DOT1L.

scientific article

Estrogen Promotes ER-Negative Tumor Growth and Angiogenesis through Mobilization of Bone Marrow-Derived Monocytes

scientific article published on 30 March 2012

Estrogen expands breast cancer stem-like cells through paracrine FGF/Tbx3 signaling ⬇️

scientific article published on November 22, 2010

Extracellular superoxide dismutase inhibits hepatocyte growth factor-mediated breast cancer-fibroblast interactions

scientific article published on 10 November 2017

Fibroblast-secreted hepatocyte growth factor mediates epidermal growth factor receptor tyrosine kinase inhibitor resistance in triple-negative breast cancers through paracrine activation of Met

scientific article published on 12 July 2012

Form and function: how estrogen and progesterone regulate the mammary epithelial hierarchy

scientific article

Functional heterogeneity of breast fibroblasts is defined by a prostaglandin secretory phenotype that promotes expansion of cancer-stem like cells

scientific article

GLI1 regulates a novel neuropilin-2/α6β1 integrin based autocrine pathway that contributes to breast cancer initiation

scientific article published on 21 February 2013

Genetic predisposition directs breast cancer phenotype by dictating progenitor cell fate

scientific article

Haploinsufficiency for BRCA1 leads to cell-type-specific genomic instability and premature senescence.

scientific article published on 24 June 2015

Human breast cancer cell lines contain stem-like cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapy

scientific article published on 26 March 2008

Human breast cancer stem cell markers CD44 and CD24: enriching for cells with functional properties in mice or in man?

scientific article published in January 2007

Human breast progenitor cell numbers are regulated by WNT and TBX3.

scientific article

Humanization of the mouse mammary gland

scientific article published on January 2015

Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing

scientific article published on 01 September 2019

Identification of selective inhibitors of cancer stem cells by high-throughput screening

scientific article

Loss of RasGAP Tumor Suppressors Underlies the Aggressive Nature of Luminal B Breast Cancers

scientific article published on 14 December 2016

Loss of Slug Compromises DNA Damage Repair and Accelerates Stem Cell Aging in Mammary Epithelium

scientific article published on 01 July 2019

Mapping the cellular and molecular heterogeneity of normal and malignant breast tissues and cultured cell lines ⬇️

scientific article published on October 21, 2010

Mechanisms of HERV-K (HML-2) Transcription during Human Mammary Epithelial Cell Transformation

scientific article published on 14 December 2017

Molecular regulation of Snai2 in development and disease

scientific article published on 02 December 2019

NDY1/KDM2B functions as a master regulator of polycomb complexes and controls self-renewal of breast cancer stem cells

scientific article published on 22 May 2014

Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state

scientific article

Obesity Promotes Breast Cancer by CCL2-Mediated Macrophage Recruitment and Angiogenesis ⬇️

scientific article published on August 19, 2013

Phenotypic Plasticity: Driver of Cancer Initiation, Progression, and Therapy Resistance

scientific article published on 13 December 2018

Portable two-color in vivo flow cytometer for real-time detection of fluorescently-labeled circulating cells

scientific article published on March 2007

Pregnancy-associated breast cancers are driven by differences in adipose stromal cells present during lactation

scientific article published on 09 January 2014

Premature polyadenylation of MAGI3 is associated with diminished N6-methyladenosine in its large internal exon

scientific article

Premature polyadenylation of MAGI3 produces a dominantly-acting oncogene in human breast cancer.

scientific article published on 20 May 2016

Promoter expression of HERV-K (HML-2) provirus-derived sequences is related to LTR sequence variation and polymorphic transcription factor binding sites

scholarly article by Meagan Montesion published in August 2018

Rapid three-dimensional quantification of voxel-wise collagen fiber orientation.

scientific article published on 3 June 2015

Reconstruction of functionally normal and malignant human breast tissues in mice

scholarly article

Reconstruction of human mammary tissues in a mouse model

scientific article published on 01 January 2006

Reply to Maguer-Satta et al.: Revisiting the mammosphere assay.

scientific article published on 22 November 2011

SLUG: Critical regulator of epithelial cell identity in breast development and cancer

scientific article

Stem Cell Maintenance of the Mammary Gland: It Takes Two

scientific article published on 01 December 2011

Stroma in breast development and disease.

scientific article

Stroma: tumor agonist or antagonist

scientific article

Stromal biomarkers in breast cancer development and progression ⬇️

scientific article published on June 10, 2012

Systemic stromal effects of estrogen promote the growth of estrogen receptor-negative cancers

scientific article published on 01 March 2007

The Hippo transducer TAZ interacts with the SWI/SNF complex to regulate breast epithelial lineage commitment

scientific article

The RasGAP gene, RASAL2, is a tumor and metastasis suppressor

scientific article published on September 2013

The SIRT2 Deacetylase Stabilizes Slug to Control Malignancy of Basal-like Breast Cancer.

scientific article published on October 2016

The Tumor Stromal Microenvironment as Modulator of Malignant Behavior ⬇️

scientific article published on 01 December 2010

The contribution of dynamic stromal remodeling during mammary development to breast carcinogenesis

scientific article

The evolving paradigm of tissue-specific metastasis

scientific article

The fibroblast Tiam1-osteopontin pathway modulates breast cancer invasion and metastasis

scientific article published on 28 January 2016

The melanocyte differentiation program predisposes to metastasis after neoplastic transformation

scientific article

Ultra-sensitive protein detection via Single Molecule Arrays towards early stage cancer monitoring

scientific article published on 8 June 2015

Using defined finger–finger interfaces as units of assembly for constructing zinc-finger nucleases ⬇️

scientific article published on January 8, 2013

Working stiff: how obesity boosts cancer risk

scientific article published on August 2015

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