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List of works by Kıvanç Birsoy

A CRISPR screen identifies a pathway required for paraquat-induced cell death

scientific article published on 23 October 2017

A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate

scientific article

A comparative perspective on lipid storage in animals

scientific article published in April 2013

A critical role for mTORC1 in erythropoiesis and anemia

scientific article

A link between metabolic energetics and pancreatic cancer mechanosensing

scientific article published on 01 January 2020

A muscle-specific knockout implicates nuclear receptor coactivator MED1 in the regulation of glucose and energy metabolism

scientific article

ATRAID regulates the action of nitrogen-containing bisphosphonates on bone

scientific article published on 01 May 2020

Absolute Quantification of Matrix Metabolites Reveals the Dynamics of Mitochondrial Metabolism

scientific article published on August 2016

Adaptive stimulation of macropinocytosis overcomes aspartate limitation in cancer cells under hypoxia

scientific article published in 2022

Adipocyte-Derived Lipids Mediate Melanoma Progression via FATP Proteins

scientific article published on 14 June 2018

Amplification of Adipogenic Commitment by VSTM2A

scientific journal article

An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis

scientific article published in July 2015

Analysis of gene networks in white adipose tissue development reveals a role for ETS2 in adipogenesis

scientific article

Antidiabetic effects of IGFBP2, a leptin-regulated gene

scientific article published on January 2010

Aspartate is a limiting metabolite for cancer cell proliferation under hypoxia and in tumours

scientific article published on 25 June 2018

Autoregulatory control of mitochondrial glutathione homeostasis

scientific article published on 02 November 2023

CHP1 Regulates Compartmentalized Glycerolipid Synthesis by Activating GPAT4

scientific article published on 04 March 2019

Cellular program controlling the recovery of adipose tissue mass: An in vivo imaging approach.

scholarly article

Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients

article

Comprehensive Characterization of Cancer Driver Genes and Mutations

article

Corrigendum to "Nuclear Factor-Y is an adipogenic factor that regulates leptin gene expression"[Mol Metab 4 (2015) 392-405]

scientific article published on 6 June 2015

Corrigendum: A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate

scientific article

DEPTOR cell-autonomously promotes adipogenesis, and its expression is associated with obesity.

scientific article

Deciphering cellular heterogeneity of pancreatic tumours

scientific article published on 01 November 2019

Dietary thiamine influences l-asparaginase sensitivity in a subset of leukemia cells

scientific article published on 09 October 2020

Drugging ACAT1 for Cancer Therapy

scientific article published in December 2016

Dysregulation of a long noncoding RNA reduces leptin leading to a leptin-responsive form of obesity

scientific article published on 06 March 2019

Functional Genomics In Vivo Reveal Metabolic Dependencies of Pancreatic Cancer Cells

scientific article published on 28 October 2020

Functional genomics reveal that the serine synthesis pathway is essential in breast cancer

scientific article

Germline SDHA mutations in children and adults with cancer

scientific article published on 01 August 2018

Identification and characterization of essential genes in the human genome.

scientific article

Identification of biologically active PDE11-selective inhibitors using a yeast-based high-throughput screen

scientific article

Identification of white adipocyte progenitor cells in vivo

scientific article published on 02 October 2008

Inhibition of ATPIF1 ameliorates severe mitochondrial respiratory chain dysfunction in mammalian cells.

scientific article

Limitation of adipose tissue by the number of embryonic progenitor cells

scientific article published on 26 May 2020

MCT1-mediated transport of a toxic molecule is an effective strategy for targeting glycolytic tumors

scientific article

MITO-Tag Mice enable rapid isolation and multimodal profiling of mitochondria from specific cell types in vivo

scientific article published on 12 December 2018

Maintaining Iron Homeostasis Is the Key Role of Lysosomal Acidity for Cell Proliferation

scientific article published on 23 January 2020

Metabolic coessentiality mapping identifies C12orf49 as a regulator of SREBP processing and cholesterol metabolism

scientific article published on 01 June 2020

Metabolic determinants of cancer cell sensitivity to canonical ferroptosis inducers

scientific article published on 10 August 2020

Metabolic determinants of cancer cell sensitivity to glucose limitation and biguanides.

scientific article

Molecular Characterization and Clinical Relevance of Metabolic Expression Subtypes in Human Cancers

scientific article published in April 2018

Molecular profiling of activated neurons by phosphorylated ribosome capture

scientific article

NFS1 undergoes positive selection in lung tumours and protects cells from ferroptosis

scientific article published on 22 November 2017

Nuclear Factor-Y is an adipogenic factor that regulates leptin gene expression

scientific article published on 13 February 2015

PIK3CA mutant tumors depend on oxoglutarate dehydrogenase

scientific article published on 10 April 2017

Publisher Correction: Aspartate is a limiting metabolite for cancer cell proliferation under hypoxia and in tumours

scientific article published on 01 October 2018

SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance.

scientific article

SUMO-1 modification of human transcription factor (TF) IID complex subunits: inhibition of TFIID promoter-binding activity through SUMO-1 modification of hsTAF5

scientific article

Serine Catabolism by SHMT2 Is Required for Proper Mitochondrial Translation Initiation and Maintenance of Formylmethionyl-tRNAs

scientific article published in February 2018

Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death

scientific article published on 13 February 2019

Target identification reveals lanosterol synthase as a vulnerability in glioma

scientific article published on 28 March 2019

Targeting extracellular nutrient dependencies of cancer cells

scientific article published on 23 November 2019

The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

article

The Transsulfuration Pathway Makes, the Tumor Takes

scientific article published on 01 November 2019

The adaptor protein p66Shc inhibits mTOR-dependent anabolic metabolism

scientific article

The anticancer natural product ophiobolin A induces cytotoxicity by covalent modification of phosphatidylethanolamine

scientific article published on 12 July 2016

The role of metabolism in cellular processes

scientific article published on 01 March 2019

The serine hydroxymethyltransferase-2 (SHMT2) initiates lymphoma development through epigenetic tumor suppressor silencing

scientific article published on 22 June 2020

Transcriptional regulation of adipogenesis by KLF4 ⬇️

scientific journal article

Untuning the tumor metabolic machine: Targeting cancer metabolism: a bedside lesson ⬇️

scientific article published on July 6, 2012

ZBTB1 Regulates Asparagine Synthesis and Leukemia Cell Response to L-Asparaginase

scientific article published on 01 April 2020

mTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake.

scientific article

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