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List of works by Paul A Gurbel

"Blueprinting" thrombogenicity and antithrombotic drug response at the bedside in patients presenting emergently with symptoms of acute stroke

scientific article published on 01 February 2019

"Sirolimus or paclitaxel drug eluting stent in left main disease: the winner is... ".

scientific article published on 10 September 2011

A Bigger Look Into the "Therapeutic Window" of Platelet Reactivity to Adenosine Diphosphate

scientific article

A narrative review of the cardiovascular risks associated with concomitant aspirin and NSAID use

article

A new method of representing drug-induced platelet inhibition: better description of time course, response variability, non-response, and heightened activity

scientific article

A randomized, double-blind, active-controlled phase 2 trial to evaluate a novel selective and reversible intravenous and oral P2Y12 inhibitor elinogrel versus clopidogrel in patients undergoing nonurgent percutaneous coronary intervention: the INNOV

scientific article published on 29 May 2012

ANTARCTIC: platelet function testing to adjust therapy

AS-302 Influence of Platelet Reactivity and Inflammation on Peri-procedural Myonecrosis in East Asian Patients Undergoing Elective Percutaneous Coronary Intervention

article

AZD6140.

scientific article published on February 2007

Abstract 2362: Myonecrosis is Predicted by Lack of Platelet Inhibition Measured in Response to Multiple Agonists in Patients Undergoing Elective Stenting:The Risk of A Global High Platelet Reactivity Phenotype

scientific article published on 03 July 2021

Acceptance of high platelet reactivity as a risk factor: now, what do we do about it?

scientific article published on October 2010

Acetylsalicylic acid and clopidogrel hyporesponsiveness following acute coronary syndromes

scientific article published on 09 August 2018

Adenosine diphosphate–induced platelet-fibrin clot strength: A new thrombelastographic indicator of long-term poststenting ischemic events ⬇️

scientific article published on August 1, 2010

Adhesion molecules, platelet activation, and cardiovascular risk

scientific article published on 01 February 2002

Advances in antiplatelet therapy: agents in clinical development

scientific article published on February 2009

Advocating cardiovascular precision medicine with P2Y12 receptor inhibitors

scientific article published on 15 February 2017

Age-Related 2-Year Mortality After Transcatheter Aortic Valve Replacement: the YOUNG TAVR Registry

scientific article published on 27 February 2019

An Ex Vivo Study to Evaluate the Effect of Tegaserod on Platelet Activation and Aggregation

scientific article published on 16 July 2020

An initial experiment with personalized antiplatelet therapy: the GRAVITAS trial

scientific article published on 01 March 2011

Another Unmet Need against Residual Risk of Atherosclerotic Cardiovascular Disease: Can "Thrombin Pathway" Be a New Target for Therapy?

scientific article published on 01 September 2020

Antiplatelet Effect Durability of a Novel, 24-Hour, Extended-Release Prescription Formulation of Acetylsalicylic Acid in Patients With Type 2 Diabetes Mellitus.

scientific article published on 20 September 2016

Antiplatelet and anticoagulant agents in heart failure: current status and future perspectives

scientific article published on 08 January 2014

Antiplatelet drug resistance and variability in response: the role of antiplatelet therapy monitoring

scientific article published on January 2013

Antiplatelet effects of aspirin with phytosterols: comparison with non-enteric coated aspirin alone.

scientific article published on 15 May 2009

Antiplatelet strategies: evaluating their current role in the setting of acute coronary syndromes.

scientific article published on March 2008

Antiplatelet therapy after implantation of drug-eluting stents: duration, resistance, alternatives, and management of surgical patients

scientific article published on October 2007

Antiplatelet therapy and platelet function testing.

scientific article published in March 2008

Antiplatelet therapy and platelet function testing. Introduction.

scientific article published in March 2008

Antiplatelet therapy beyond 2012: role of personalized medicine

scientific article published on January 1, 2012

Antiplatelet therapy: Clopidogrel-PPI interaction, an ongoing controversy

scientific article published on 01 January 2011

Antiplatelet therapy: current strategies and future trends

scientific article published on May 2006

Antiplatelet treatment for prevention of cerebrovascular events in patients with vascular diseases: a systematic review and meta-analysis

scientific article published on 24 December 2013

Antiplatelet treatment of cardiovascular disease: a translational research perspective

scientific article published on 01 May 2008

Antithrombotic Strategies and Device Thrombosis

scientific article published on 15 September 2018

Aspirin and clopidogrel resistance: consideration and management

scientific article (publication date: October 2006)

Aspirin as an Adjunctive Pharmacologic Therapy Option for COVID-19: Anti-Inflammatory, Antithrombotic, and Antiviral Effects All in One Agent

scientific article published in 2021

Aspirin resistance

scientific article published on September 2009

Assessing platelet reactivity after drug eluting stent implantation: state of the art

scientific article published on 01 January 2020

Assessing the current role of platelet function testing.

scientific article published on March 2008

Assessment of clopidogrel responsiveness: measurements of maximum platelet aggregation, final platelet aggregation and their correlation with vasodilator-stimulated phosphoprotein in resistant patients

scientific article published on 02 April 2007

Association Between Baseline LDL-C Level and Total and Cardiovascular Mortality After LDL-C Lowering: A Systematic Review and Meta-analysis.

scientific article published in April 2018

Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy

scientific article

Association of weight gain with coronary artery disease, inflammation and thrombogenicity.

scientific article

Baseline low-density lipoprotein cholesterol to predict the extent of cardiovascular benefit from lipid-lowering therapies: a review

scientific article published on 01 January 2019

Biomarker analysis by fluorokine multianalyte profiling distinguishes patients requiring intervention from patients with long-term quiescent coronary artery disease: a potential approach to identify atherosclerotic disease progression

scientific article

Bivalirudin and clopidogrel with and without eptifibatide for elective stenting: effects on platelet function, thrombelastographic indexes, and their relation to periprocedural infarction results of the CLEAR PLATELETS-2 (Clopidogrel with Eptifibati

scientific article

Bleeding and stent thrombosis on P2Y12-inhibitors: collaborative analysis on the role of platelet reactivity for risk stratification after percutaneous coronary intervention

scientific article published on 20 April 2015

Bleeding and thrombosis associated with ventricular assist device therapy

scientific article published on 11 May 2017

Can an Old Ally Defeat a New Enemy?

scientific article published on 01 June 2020

Cangrelor for the treatment of patients with Arterial Thrombosis

scientific article published on 13 August 2018

Cardiac mortality in patients randomised to elective coronary revascularisation plus medical therapy or medical therapy alone: a systematic review and meta-analysis

scientific article published in December 2021

CardioPulse: Platelet inhibitors and their differences

scientific article published in January 2016

Cardiovascular safety of NSAIDs: Additional insights after PRECISION and point of view.

scientific article published on 16 December 2017

Caution in interpreting the findings from small observational studies

scientific article published on 15 June 2012

Cell-Penetrating Pepducin Therapy Targeting PAR1 in Subjects With Coronary Artery Disease

scientific article published on 17 December 2015

Central aortic pulse pressure, thrombogenicity and cardiovascular risk.

scientific article published on 10 July 2017

Cigarette Smoking, Clopidogrel Responsiveness, and Hemoglobin Level

scientific article published on 01 November 2016

Cigarette smoking and clopidogrel interaction

scientific article published on May 2013

Cilostazol to Overcome High On-Treatment Platelet Reactivity in Korean Patients Treated With Clopidogrel and Calcium-Channel Blocker ⬇️

scientific article published on 05 October 2011

Circulating MicroRNA Profiling in Non-ST Elevated Coronary Artery Syndrome Highlights Genomic Associations with Serial Platelet Reactivity Measurements

scientific article published on 10 April 2020

Clinical applications of antiplatelet therapy

scientific article (publication date: 2006)

Clinical considerations with the use of antiplatelet therapy in patients undergoing percutaneous coronary intervention

scientific article published on March 2008

Clopidogrel and proton pump inhibitors: influence of pharmacological interactions on clinical outcomes and mechanistic explanations

scientific article published on April 2011

Clopidogrel effect on platelet reactivity in patients with stent thrombosis: results of the CREST Study

scientific article

Clopidogrel for coronary stenting: response variability, drug resistance, and the effect of pretreatment platelet reactivity

scientific article (publication date: 17 June 2003)

Clopidogrel loading with eptifibatide to arrest the reactivity of platelets: results of the Clopidogrel Loading With Eptifibatide to Arrest the Reactivity of Platelets (CLEAR PLATELETS) study

scientific article published on 28 February 2005

Clopidogrel metaboliser status based on point-of-care CYP2C19 genetic testing in patients with coronary artery disease

scientific article published on 09 January 2014

Clopidogrel resistance: implications for coronary stenting

scientific article (publication date: 2006)

Clopidogrel resistance?

scientific article (publication date: 2007)

Clopidogrel response variability and the advent of personalised antiplatelet therapy. A bench to bedside journey

scientific article published on 28 June 2011

Coagulation Abnormalities in Heart Failure: Pathophysiology and Therapeutic Implications

scientific article published on 4 November 2016

Combination Antiplatelet and Oral Anticoagulant Therapy in Patients With Coronary and Peripheral Artery Disease

scientific article published on 01 April 2019

Combination Oral Antithrombotic Therapy for the Treatment of Myocardial Infarction: Recent Developments.

scientific article published on 3 April 2018

Combination antithrombotic therapies

scientific article published on February 2010

Comparative Efficacy and Safety of Oral P2Y12 Inhibitors in Acute Coronary Syndrome: Network Meta-Analysis of 52,816 Patients from 12 Randomized Trials

scientific article published on 29 May 2020

Comparison of zotarolimus-eluting and sirolimus-eluting stents in patients with native coronary artery disease: a randomized controlled trial

scientific article published on 28 November 2006

Consensus and future directions on the definition of high on-treatment platelet reactivity to adenosine diphosphate.

scientific article published on September 2010

Consensus and update on the definition of on-treatment platelet reactivity to adenosine diphosphate associated with ischemia and bleeding

scientific article

Contribution of hepatic cytochrome P450 3A4 metabolic activity to the phenomenon of clopidogrel resistance

scientific article (publication date: 20 January 2004)

Controversies in Oral Antiplatelet Therapy in Patients Undergoing Aortocoronary Bypass Surgery ⬇️

scientific article published on September 1, 2010

Correction of a saphenous vein graft to coronary vein anastamosis by selective retrograde coil-induced occlusion to arterialize the native vein

scientific article published on 01 December 2002

Could stent design affect platelet activation? Results of the Platelet Activation in STenting (PAST) Study.

scientific article published in October 2002

Current antiplatelet treatment strategy in patients with diabetes mellitus

scientific article published on April 2015

Current controversies in the use of aspirin and ticagrelor for the treatment of thrombotic events

scientific article

Current options in oral antiplatelet strategies during percutaneous coronary interventions

scientific article published on January 1, 2011

Cutaneous clopidogrel hypersensitivity: give steroids and do not stop the clopidogrel

scientific article published on 01 September 2011

Dark chocolate effect on platelet activity, C-reactive protein and lipid profile: a pilot study

scientific article

Deciding about prolonged ticagrelor therapy in coronary clot formers: an ongoing dilemma

scientific article

Decrease in high on-treatment platelet reactivity (HPR) prevalence on switching from clopidogrel to prasugrel: Insights from the switching anti-platelet (SWAP) study ⬇️

scientific article published on 06 December 2012

Defining platelet response to acetylsalicylic acid: the relation between inhibition of serum thromboxane B2 and agonist-induced platelet aggregation

scientific article published on 10 November 2020

Delayed thrombin-induced platelet-fibrin clot generation by clopidogrel: a new dose-related effect demonstrated by thrombelastography in patients undergoing coronary artery stenting

scientific article (publication date: 2007)

Delivery of glycoprotein IIb/IIIa inhibitor therapy for percutaneous coronary intervention: why not take the intracoronary highway?

scientific article published in February 2010

Detailed thrombogenicity phenotyping and 1 year outcomes in patients undergoing WATCHMAN implantation: (TARGET-WATCHMAN) a case-control study

scientific article published on 29 June 2020

Determination of non-Vitamin K oral anticoagulant (NOAC) effects using a new-generation thrombelastography TEG 6s system

scientific article

Diagnostics for aspirin resistance

scientific article

Direct oral anticoagulants: a review on the current role and scope of reversal agents

scientific article published on 01 February 2020

Do East Asians have different hypercoagulable states compared with Western population? ⬇️

scientific article published on June 12, 2011

Do platelet function testing and genotyping improve outcome in patients treated with antithrombotic agents?: platelet function testing and genotyping improve outcome in patients treated with antithrombotic agents

scientific article published on 01 March 2012

Does Gender have an Influence on Platelet Function and the Efficacy of Oral Antiplatelet Therapy?

scientific article published on 11 February 2012

Does Platelet Reactivity Predict Bleeding in Patients Needing Urgent Coronary Artery Bypass Grafting During Dual Antiplatelet Therapy?

scientific article published on July 2016

Drug delivery and therapeutic impact of extended-release acetylsalicylic acid

scientific article published on 10 September 2015

Drug insight: Clopidogrel nonresponsiveness

scientific article (publication date: July 2006)

Drug-coated balloons in treatment of in-stent restenosis: a meta-analysis of randomised controlled trials

scientific article published on 20 December 2012

Dual vs single antiplatelet therapy in patients with lower extremity peripheral artery disease - A meta-analysis

article

Durability of platelet inhibition by clopidogrel ⬇️

scientific article (publication date: May 2003)

Effect of Smoking Cessation on the Pharmacokinetics and Pharmacodynamics of Clopidogrel after PCI: The Smoking Cessation Paradox Study

scientific article published on 15 January 2020

Effect of angiotensin-converting enzyme inhibitors, beta blockers, statins, and aspirin on C-reactive protein levels in outpatients with heart failure

scientific article (publication date: 15 March 2004)

Effect of clopidogrel with and without eptifibatide on tumor necrosis factor-alpha and C-reactive protein release after elective stenting: results from the CLEAR PLATELETS 1b study

scientific article published in December 2006

Effect of eptifibatide for acute coronary syndromes: rapid versus late administration--therapeutic yield on platelets (The EARLY Platelet Substudy).

scientific article published in December 2002

Effect of loading with clopidogrel at the time of coronary stenting on platelet aggregation and glycoprotein IIb/IIIa expression and platelet-leukocyte aggregate formation

scientific article

Effect of long-term clopidogrel treatment on platelet function and inflammation in patients undergoing coronary arterial stenting.

scientific article

Effects of Proprotein Convertase Subtilisin/Kexin Type 9 Antibodies in Adults With Hypercholesterolemia: A Systematic Review and Meta-analysis

scientific article

Effects of roxifiban on platelet aggregation and major receptor expression in patients with coronary artery disease for the Roxifiban Oral Compound Kinetics Evaluation Trial-I (ROCKET-I Platelet Substudy)

scientific article (publication date: July 2003)

Effects of vorapaxar on clot characteristics, coagulation, inflammation, and platelet and endothelial function in patients treated with mono- and dual-antiplatelet therapy

scientific article published on 17 September 2019

Efficacy and safety of intracoronary epinephrine versus conventional treatments alone in STEMI patients with refractory coronary no-reflow during primary PCI: The RESTORE observational study

scientific article published on 17 July 2020

Efficacy of aspirin (325 mg) + omeprazole (40 mg) in treating coronary artery disease

scientific article published on 12 December 2016

Efficacy of cilostazol on inhibition of platelet aggregation, inflammation and myonecrosis in acute coronary syndrome patients undergoing percutaneous coronary intervention: The ACCEL-LOADING-ACS (ACCELerated Inhibition of Platelet Aggregation, Infl

scientific article published on 23 April 2015

Erythropoietin therapy after out-of-hospital cardiac arrest: A systematic review and meta-analysis.

scientific article published in December 2017

Evaluation of dose-related effects of aspirin on platelet function: results from the Aspirin-Induced Platelet Effect (ASPECT) study

scientific article (publication date: 26 June 2007)

Evaluation of platelets in heart failure: is platelet activity related to etiology, functional class, or clinical outcomes?

scientific article (publication date: June 2002)

Exploration of PCSK9 as a Cardiovascular Risk Factor: Is There a Link to the Platelet?

scientific article published in September 2017

Extended-release acetylsalicylic acid for secondary prevention of stroke and cardiovascular events.

scientific article published on 23 May 2016

Failure of clopidogrel to reduce platelet reactivity and activation following standard dosing in elective stenting: implications for thrombotic events and restenosis

scientific article (publication date: March 2004)

First In-Human Experience With Inhaled Acetylsalicylic Acid for Immediate Platelet Inhibition: Comparison With Chewed and Swallowed Acetylsalicylic Acid

scientific article published on 28 September 2020

First analysis of the relation between CYP2C19 genotype and pharmacodynamics in patients treated with ticagrelor versus clopidogrel: the ONSET/OFFSET and RESPOND genotype studies.

scientific article

First report of the point-of-care TEG: A technical validation study of the TEG-6S system

scientific article published on 11 April 2016

Further Ex Vivo Evidence Supporting Higher Aspirin Dosing in Patients With Coronary Artery Disease and Diabetes ⬇️

scientific article published on 01 April 2011

G-protein-coupled receptors signaling pathways in new antiplatelet drug development

scientific article

GEMINI-ACS-1: toward unearthing the antithrombotic therapy cornerstone for acute coronary syndromes.

scientific article

Genetic variation in PEAR1 is associated with platelet aggregation and cardiovascular outcomes

scientific article published on 07 February 2013

Genome-wide and candidate gene approaches of clopidogrel efficacy using pharmacodynamic and clinical end points-Rationale and design of the International Clopidogrel Pharmacogenomics Consortium (ICPC).

scientific article published on 17 December 2017

Genome-wide association study of platelet reactivity and cardiovascular response in patients treated with clopidogrel: a study by the International Clopidogrel Pharmacogenomics Consortium (ICPC)

scientific article published on 30 May 2020

Genotyping: one piece of the puzzle to personalize antiplatelet therapy

scientific article

HDL3-C is a Marker of Coronary Artery Disease Severity and Inflammation in Patients on Statin Therapy

scientific article published on 27 December 2018

HIV infection, ACS, PCI and high platelet reactivity: ingredients for a perfect thrombotic storm

scientific article published on 12 January 2017

High Residual Platelet Reactivity during Aspirin Therapy in Patients with Non-St Segment Elevation Acute Coronary Syndrome: Comparison Between Initial and Late Phases

scientific article published on 15 August 2019

High platelet reactivity to multiple agonists during aspirin and clopidogrel treatment is indicative of a global hyperreactive platelet phenotype.

scientific article published on 10 November 2011

High-dose, but not low-dose, aspirin impairs anticontractile effect of ticagrelor following ADP stimulation in rat tail artery smooth muscle cells

scientific article published on 06 June 2013

Hypercoagulability, platelet function, inflammation and coronary artery disease acuity: results of the Thrombotic RIsk Progression (TRIP) study

scientific article published on 01 January 2010

Hypothesis formulation from subgroup analyses: nonadherence or nonsteroidal anti-inflammatory drug use explains the lack of clinical benefit of aspirin on first myocardial infarction attributed to "aspirin resistance".

scientific article published in May 2010

Immunity to thrombotic events is achievable if we stop the guessing game: Is this the major hidden message from GRAVITAS? ⬇️

scientific article published on 05 May 2011

Impact of Anemia on Platelet Reactivity and Ischemic and Bleeding Risk: From the Assessment of Dual Antiplatelet Therapy With Drug-Eluting Stents Study

scientific article

Impact of Aspirin and Clopidogrel Hyporesponsiveness in Patients Treated With Drug-Eluting Stents: 2-Year Results of a Prospective, Multicenter Registry Study

scientific article published on 27 July 2017

Impact of CYP2C19 Metabolizer Status on Patients With ACS Treated With Prasugrel Versus Clopidogrel

scientific article

Impact of smoking status on platelet function and clinical outcomes with prasugrel vs. clopidogrel in patients with acute coronary syndromes managed without revascularization: Insights from the TRILOGY ACS trial

scientific article published on 24 April 2014

Implantable Cardioverter-Defibrillators for Primary Prevention in Patients With Ischemic or Nonischemic Cardiomyopathy: A Systematic Review and Meta-analysis.

scientific article published on 27 June 2017

Importance of measurement of platelet reactivity to ADP in patients with coronary artery disease: an historical account

scientific article published on 23 October 2013

Importance of potent P2Y(12) receptor blockade in acute myocardial infarction: focus on prasugrel

scientific article published on 12 July 2012

In search for an optimal antithrombotic regimen in patients with atrial fibrillation undergoing stenting

scientific article published on 23 September 2019

Incidence of dyspnea and assessment of cardiac and pulmonary function in patients with stable coronary artery disease receiving ticagrelor, clopidogrel, or placebo in the ONSET/OFFSET study

scientific article published on July 2010

Increased platelet inhibition after switching from maintenance clopidogrel to prasugrel in patients with acute coronary syndromes: results of the SWAP (SWitching Anti Platelet) study

scientific article published on September 2010

Increased risk in patients with high platelet aggregation receiving chronic clopidogrel therapy undergoing percutaneous coronary intervention: is the current antiplatelet therapy adequate?

scientific article (publication date: 13 February 2007)

Inflammatory changes during the 'common cold' are associated with platelet activation and increased reactivity of platelets to agonists

scientific article published in December 2007

Influence of Amlodipine on Haemostatic Measurements during Clopidogrel Treatment in Patients with Coronary Artery Disease

scientific article published on 04 January 2019

Influence of genetic polymorphisms on platelet function, response to antiplatelet drugs and clinical outcomes in patients with coronary artery disease

scientific article

Influence of race and sex on thrombogenicity in a large cohort of coronary artery disease patients

scientific article

Inhibited and Uninhibited Platelet Deposition Within a Thrombus: Does It Depend on the Antiplatelet Drug?

scientific article published on 01 October 2015

Inhibition of platelet aggregation by AZD6140, a reversible oral P2Y12 receptor antagonist, compared with clopidogrel in patients with acute coronary syndromes

scientific article published on 23 October 2007

Interaction between clopidogrel and proton-pump inhibitors and management strategies in patients with cardiovascular diseases ⬇️

scientific article published on November 15, 2010

International Expert Consensus on Switching Platelet P2Y12 Receptor-Inhibiting Therapies

scientific article published on 30 October 2017

Investigating the mechanisms of hyporesponse to antiplatelet approaches

scientific article published on March 2008

Is There a Role for Preoperative Platelet Function Testing in Patients Undergoing Cardiac Surgery During Antiplatelet Therapy?

scientific article published on 01 November 2018

Is light transmittance aggregometry still a useful tool to assess pharmacodynamic effects of antiplatelet therapy?

scientific article published on 27 May 2014

Late-term clinical outcomes with zotarolimus- and sirolimus-eluting stents. 5-year follow-up of the ENDEAVOR III (A Randomized Controlled Trial of the Medtronic Endeavor Drug [ABT-578] Eluting Coronary Stent System Versus the Cypher Sirolimus-Elutin

scientific article published on 01 May 2011

Letter by Grbel et al regarding article, "administration of a loading dose has no additive effect on platelet aggregation during the switch from ongoing clopidogrel treatment to ticagrelor in patients with acute coronary syndrome"

scientific article published on 01 April 2014

Letter by Gurbel et al regarding article, "Cytochrome 2C19*17 allelic variant, platelet aggregation, bleeding events, and stent thrombosis in clopidogrel-treated patients with coronary stent placement".

scientific article published on October 2010

Low-density lipoprotein 4: a novel predictor of coronary artery disease severity.

scientific article

Low-dose ticagrelor with or without acetylsalicylic acid in patients with acute coronary syndrome: Rationale and design of the ELECTRA-SIRIO 2 trial

scientific article published in 2022

Meta-Analysis of the Usefulness of Therapeutic Hypothermia After Cardiac Arrest

scientific article published on 24 July 2020

Meta-analysis of direct and indirect comparison of ticagrelor and prasugrel effects on platelet reactivity

scientific article

More Evidence for Non-P2Y12-Mediated Effects of Ticagrelor

scientific article published in August 2017

Neutral effect on markers of heart failure, inflammation, endothelial activation and function, and vagal tone after high-dose HMG-CoA reductase inhibition in non-diabetic patients with non-ischemic cardiomyopathy and average low-density lipoprotein

scientific article published on 20 December 2005

Noncanonical Matrix Metalloprotease 1-Protease-Activated Receptor 1 Signaling Drives Progression of Atherosclerosis.

scientific article published on 5 April 2018

Novel antiplatelet agents in cardiovascular medicine

scientific article published on 01 June 2015

Omeprazole: a possible new candidate influencing the antiplatelet effect of clopidogrel

scientific article

Onset and extent of platelet inhibition by clopidogrel loading in patients undergoing elective coronary stenting: the Plavix Reduction Of New Thrombus Occurrence (PRONTO) trial

scientific article published in February 2003

Optimal timing of coronary invasive strategy in non-ST-segment elevation acute coronary syndromes: a systematic review and meta-analysis

scientific article published on February 2013

Outcomes of Patients Receiving Downstream Revascularization After Initial Medical Management for Non-ST-Segment Elevation Acute Coronary Syndromes (From the TRILOGY ACS Trial)

scientific article published on 19 July 2018

Outcomes with the polymer-based paclitaxel-eluting TAXUS stent in patients with diabetes mellitus: the TAXUS-IV trial

scientific article published in April 2005

Overestimation of platelet aspirin resistance detection by thrombelastograph platelet mapping and validation by conventional aggregometry using arachidonic acid stimulation

scientific article (publication date: November 2005)

Oxidized Low-Density Lipoprotein-β2-Glycoprotein I Complex But Not Free Oxidized LDL Is Associated With the Presence and Severity of Coronary Artery Disease

scientific article published on 15 June 2016

P2Y12 Receptor Blockade and Myocardial Perfusion

scientific article published in July 2013

P2Y12 receptor inhibitors for secondary prevention of ischemic stroke

scientific article published on 14 April 2015

PA tablets: investigational compounds combining aspirin and omeprazole for cardioprotection.

scientific article

PAR1 (Protease-Activated Receptor 1) Pepducin Therapy Targeting Myocardial Necrosis in Coronary Artery Disease and Acute Coronary Syndrome Patients Undergoing Cardiac Catheterization: A Randomized, Placebo-Controlled, Phase 2 Study

scientific article published on 08 October 2020

PCSK9 Inhibition During the Inflammatory Stage of SARS-CoV-2 Infection

PRASFIT-ACS: important evidence against a "one-guideline-fits-all-races" approach to antiplatelet therapy

scientific article published on 16 September 2014

Peri-Procedural Platelet Reactivity in Percutaneous Coronary Intervention

scientific article published on 04 June 2018

Peri-operative platelet function testing: The potential for reducing ischaemic and bleeding risks ⬇️

scientific article published on April 20, 2011

Peri-procedural platelet function and platelet inhibition in percutaneous coronary intervention

scientific article published on April 2008

Personalized antiplatelet therapy: state of the art.

scientific article published on 24 September 2012

Personalizing Antithrombotic Therapy in COVID-19: Role of Thromboelastography and Thromboelastometry

scientific article published on 17 July 2020

Pharmacodynamic effect of cilostazol plus standard clopidogrel versus double-dose clopidogrel in patients with type 2 diabetes undergoing percutaneous coronary intervention

scientific article

Pharmacodynamic effects of cilostazol versus clopidogrel in stented patients under proton pump inhibitor co-administration: the ACCEL-PARAZOL study.

scientific article

Pharmacodynamic evaluation of switching from ticagrelor to prasugrel in patients with stable coronary artery disease: Results of the SWAP-2 Study (Switching Anti Platelet-2).

scientific article published on 12 December 2013

Pharmacodynamic profile in East Asian patients with ACS treated with prasugrel standard-dose v de-escalation strategy: a randomized A-MATCH trial

scientific article published on 05 January 2021

Pharmacodynamics, pharmacokinetics, and safety of single-dose subcutaneous administration of selatogrel, a novel P2Y12 receptor antagonist, in patients with chronic coronary syndromes

scientific article published on 14 November 2019

Pharmacogenetic guidance for antiplatelet treatment.

scientific article

Pharmacogenomic Polygenic Response Score Predicts Ischemic Events and Cardiovascular Mortality in Clopidogrel-Treated Patients

scientific article published on 03 September 2019

Pharmacokinetic and pharmacodynamic effects of elinogrel: results of the platelet function substudy from the intravenous and oral administration of elinogrel to evaluate tolerability and efficacy in nonurgent percutaneous coronary intervention patie

scientific article published on 22 May 2012

Pharmacokinetic-pharmacodynamic modelling of platelet response to ticagrelor in stable coronary artery disease and prior myocardial infarction patients

scientific article published on 18 December 2018

Pharmacokinetics and pharmacodynamics of ticagrelor in patients with stable coronary artery disease: results from the ONSET-OFFSET and RESPOND studies

scientific article published on 01 June 2012

Pharmacology of antiplatelet agents

scientific article published on December 2013

Platelet Function Testing Before CABG is Recommended in the Guidelines: But Do We Have Enough Evidence?

scientific article published on 01 June 2015

Platelet Function Testing in Patients on Antiplatelet Therapy before Cardiac Surgery

scientific article published on 04 September 2020

Platelet Inhibition and Bleeding in Patients Undergoing Non-Cardiac Surgery-The BIANCA Observational Study

scientific article published on 06 April 2018

Platelet P2Y12 receptor antagonist pharmacokinetics and pharmacodynamics: A foundation for distinguishing mechanisms of bleeding and anticipated risk for platelet-directed therapies

scientific article published on 02 February 2010

Platelet Reactivity and Risk of Ischemic Stroke After Coronary Drug-Eluting Stent Implantation: From the ADAPT-DES Study

scientific article published on 13 June 2018

Platelet activation after stenting with heparin-coated versus noncoated stents ⬇️

scientific article (publication date: October 2003)

Platelet activation and pneumonia: is soluble p-selectin the right marker?

scientific article published on 01 April 2015

Platelet activation in myocardial ischemic syndromes

scientific article published in July 2004

Platelet function during extended prasugrel and clopidogrel therapy for patients with ACS treated without revascularization: the TRILOGY ACS platelet function substudy

scientific article

Platelet function measured by VerifyNow identifies generalized high platelet reactivity in aspirin treated patients

scientific article (publication date: September 2007)

Platelet function measurement in elective percutaneous coronary intervention patients: exploring the concept of a P2Y₁₂ inhibitor therapeutic window

scientific article published on 01 March 2012

Platelet function measurement-based strategy to reduce bleeding and waiting time in clopidogrel-treated patients undergoing coronary artery bypass graft surgery: the timing based on platelet function strategy to reduce clopidogrel-associated bleedin

scientific article published on 06 March 2012

Platelet function monitoring in patients with coronary artery disease

scientific article published on 23 October 2007

Platelet reactivity and clinical outcomes after coronary artery implantation of drug-eluting stents (ADAPT-DES): a prospective multicentre registry study

scientific article published on 26 July 2013

Platelet reactivity and thrombogenicity in postmenopausal women ⬇️

scientific article published on January 1, 2013

Platelet reactivity during ticagrelor maintenance therapy: a patient-level data meta-analysis

scientific article

Platelet reactivity in patients and recurrent events post-stenting: results of the PREPARE POST-STENTING Study

scientific article (publication date: 15 November 2005)

Platelet reactivity to adenosine diphosphate and long-term ischemic event occurrence following percutaneous coronary intervention: a potential antiplatelet therapeutic target

scientific article

Platelet-Mediated Thrombosis: From Bench to Bedside

scientific article published on April 2016

Point-of-care platelet function analysis ready for prime time?

scientific article published in March 2009

Potential role of oral anticoagulants in the treatment of patients with coronary artery disease: focus on dabigatran

scientific article published on 22 August 2013

Prasugrel

scientific article (publication date: December 2006)

Prasugrel 5 mg in the very elderly attenuates platelet inhibition but maintains noninferiority to prasugrel 10 mg in nonelderly patients: the GENERATIONS trial, a pharmacodynamic and pharmacokinetic study in stable coronary artery disease patients

scientific article

Prasugrel versus Clopidogrel for Acute Coronary Syndromes without Revascularization ⬇️

scientific article published on August 25, 2012

Prediction of Ischemic and Bleeding Events Using the Dual Antiplatelet Therapy Score in an Unrestricted Percutaneous Coronary Intervention Population

scientific article published on 01 October 2018

Prevalence and impact of high platelet reactivity in chronic kidney disease: results from the Assessment of Dual Antiplatelet Therapy with Drug-Eluting Stents registry

scientific article published on June 2015

Prevalence of aspirin and clopidogrel resistance among patients with and without drug-eluting stent thrombosis

scientific article published on 24 June 2009

Prevention of contrast-induced acute kidney injury in patients undergoing cardiovascular procedures-a systematic review and network meta-analysis

scientific article

Prime time for the sweet spot in timing of coronary invasive approach in patients with non-ST elevation myocardial infarction.

scientific article published in January 2018

Prolonged antithrombotic therapy in patients after acute coronary syndrome: A critical appraisal of current European Society of Cardiology guidelines

scientific article published on 19 October 2020

Prolonged antithrombotic therapy in patients after acute coronary syndrome: A critical appraisal of current European Society of Cardiology guidelines

Proprotein Convertase Subtilisin/Kexin Type 9 Monoclonal Antibodies for Acute Coronary Syndrome: A Narrative Review

scientific article published on 22 March 2016

Quantification of antibody avidities and accurate detection of SARS-CoV-2 antibodies in serum and saliva on plasmonic substrates

scientific article published on 29 October 2020

Race and sex differences in thrombogenicity: risk of ischemic events following coronary stenting

scientific article

Race-Related disparities in COVID-19 thrombotic outcomes: Beyond social and economic explanations

scientific article published on 20 November 2020

Randomized double-blind assessment of the ONSET and OFFSET of the antiplatelet effects of ticagrelor versus clopidogrel in patients with stable coronary artery disease: the ONSET/OFFSET study.

scientific article

Rapid Desensitization of the Patients With Aspirin Hypersensitivity and Coronary Artery Disease.

scientific article

Recent developments in clopidogrel pharmacology and their relation to clinical outcomes

scientific article published on August 2009

Reduced-function CYP2C19 genotype and risk of adverse clinical outcomes among patients treated with clopidogrel predominantly for PCI: a meta-analysis

scientific article

Relation of High Lipoprotein (a) Concentrations to Platelet Reactivity in Individuals with and Without Coronary Artery Disease

scientific article published on 05 September 2020

Relation of fish oil supplementation to markers of atherothrombotic risk in patients with cardiovascular disease not receiving lipid-lowering therapy

scientific article published on 12 February 2015

Relation of platelet activation and myocardial ischemia biomarkers dependent on type of chest pain (abrupt onset versus intermittent) in patients with angina pectoris or non-Q-wave acute myocardial infarction

scientific article published on 01 August 2002

Relationship of Platelet Reactivity With Bleeding Outcomes During Long-Term Treatment With Dual Antiplatelet Therapy for Medically Managed Patients With Non-ST-Segment Elevation Acute Coronary Syndromes

scientific article

Resistance to antiplatelet drugs: current status and future research

scientific article (publication date: October 2005)

Resistance to antiplatelet drugs: what progress has been made?

scientific article

Response to ticagrelor in clopidogrel nonresponders and responders and effect of switching therapies: the RESPOND study

scientific article

Response variability and the role of platelet function testing

scientific article published on April 2009

Review of pharmacokinetic and pharmacodynamic modeling and safety of proton pump inhibitors and aspirin.

scientific article published on 07 August 2014

Risk factors associated with plasma omega-3 fatty acid levels in patients with suspected coronary artery disease.

scientific article published on 18 August 2016

Role of genotype-based personalized antiplatelet therapy in the era of potent P2Y₁₂ receptor inhibitors

scientific article published on August 2012

Role of proprotein convertase subtilisin/kexin type 9 inhibitors in patients with coronary artery disease undergoing percutaneous coronary intervention

scientific article published on 23 May 2018

Selection of P2Y12 inhibitor in percutaneous coronary intervention and/or acute coronary syndrome

scientific article published on 12 January 2018

Short-term dual antiplatelet therapy (DAPT) followed by P2Y12 monotherapy versus traditional DAPT in patients undergoing percutaneous coronary intervention: meta-analysis and viewpoint

scientific article published on 01 January 2020

Should Antithrombotic Treatment Strategies in East Asians Differ from Caucasians? Focused on ACS or PCI-treated Patients

scientific article published on 16 January 2018

Smoking and cardiovascular diseases: paradox greater than expected?

scientific article published on 16 August 2019

Spaced administration of PA32540 and clopidogrel results in greater platelet inhibition than synchronous administration of enteric-coated aspirin and enteric-coated omeprazole and clopidogrel

Standardized Team-Based Care for Cardiogenic Shock

scientific article published on 01 April 2019

State of the art: Oral antiplatelet therapy

scientific article

Statin therapy and inflammation in patients with diabetes treated with high dose aspirin

scientific article published on 10 May 2016

Stent thrombosis: role of compliance and nonresponsiveness to antiplatelet therapy.

scientific article published on January 2007

Synergistic influence of rivaroxaban on inflammation and coagulation biomarkers in patients with coronary artery disease and peripheral artery disease on aspirin therapy

scientific article published on 04 March 2020

TEG®6s system measures the contributions of both platelet count and platelet function to clot formation at the site-of-care

scientific article published on 26 December 2019

Temporal Variability of Platelet Reactivity Phenotype: Another Barrier to Personalized Antiplatelet Strategy Guided by Platelet Function Testing

scientific article published on 01 November 2019

The Dogged Search for Cryptic Effects of Ticagrelor: Wishful Thinking or Real Benefits Beyond P2Y12 Inhibition?

scientific article published on 27 October 2016

The Impact of platelet-fibrin clot strength on occurrence and clinical outcomes of peripheral artery disease in patients with significant coronary artery disease

scientific article published on 11 April 2020

The Influence of CYP2C19 Polymorphisms on the Pharmacokinetics, Pharmacodynamics, and Clinical Effectiveness of P2Y12 Inhibitors ⬇️

scientific article published on January 1, 2011

The Rationale for and Clinical Pharmacology of Prasugrel 5 mg.

scientific article published on 17 November 2016

The Role of Platelet Function Testing and Genotyping in the Stented Patient Treated With Clopidogrel ⬇️

scientific article published on December 13, 2011

The Role of Platelet Function Testing in Risk Stratification and Clinical Decision-Making

scientific article published on 10 July 2013

The association of cigarette smoking with enhanced platelet inhibition by clopidogrel

scientific article

The clopidogrel-statin interaction

scientific article published on 07 February 2014

The difference between clopidogrel responsiveness and posttreatment platelet reactivity

scientific article (publication date: 2005)

The effect of St John's Wort on the pharmacodynamic response of clopidogrel in hyporesponsive volunteers and patients: increased platelet inhibition by enhancement of CYP3A4 metabolic activity

scientific article published on January 1, 2011

The effect of aspirin dosing on platelet function in diabetic and nondiabetic patients: an analysis from the aspirin-induced platelet effect (ASPECT) study

scientific article (publication date: December 2007)

The effect of ticagrelor versus clopidogrel on high on-treatment platelet reactivity: combined analysis of the ONSET/OFFSET and RESPOND studies

scientific article published on 12 June 2011

The enigmatic search for optimal DAPT duration.

scientific article published on 24 November 2013

The functional G143E variant of carboxylesterase 1 is associated with increased clopidogrel active metabolite levels and greater clopidogrel response

scientific article published on January 2013

The influence of smoking status on the pharmacokinetics and pharmacodynamics of clopidogrel and prasugrel: the PARADOX study

scientific article published on 16 April 2013

The link between heightened thrombogenicity and inflammation: pre-procedure characterization of the patient at high risk for recurrent events after stenting

scientific article published in March 2009

The next 10 years in personalized medicine in cardiology

scientific article published on 01 August 2013

The optimal antithrombotic regimen to prevent post-CABG adverse events: an ongoing controversy

scientific article published on 01 August 2019

The platelet-related effects of tenecteplase versus alteplase versus reteplase

scientific article

The problem of persistent platelet activation in acute coronary syndromes and following percutaneous coronary intervention

scientific article published on March 2008

The rationale for and comparisons of different antiplatelet treatments in acute coronary syndrome

scientific article published on December 2008

The relation between CYP2C19 genotype and phenotype in stented patients on maintenance dual antiplatelet therapy

scientific article

The relation between platelet reactivity and glycemic control in diabetic patients with cardiovascular disease on maintenance aspirin and clopidogrel therapy

scientific article published in November 2009

The relation of dosing to clopidogrel responsiveness and the incidence of high post-treatment platelet aggregation in patients undergoing coronary stenting

scientific article published in May 2005

The role of platelet receptors and adhesion molecules in coronary artery disease

scientific article

The stratification of platelet reactivity and activation in patients with stable coronary artery disease on aspirin therapy

scientific article (publication date: 2003)

The worry about clopidogrel "nonresponsiveness": identification and treatment in the post-percutaneous coronary intervention patient

scientific article published in November 2009

Thrombin-Induced Platelet-Fibrin Clot Strength Identified by Thrombelastography: A Novel Prothrombotic Marker of Coronary Artery Stent Restenosis.

scientific article

Thrombin-induced platelet-fibrin clot strength: Relation to high on-clopidogrel platelet reactivity, genotype, and post-percutaneous coronary intervention outcomes

Thromboembolism after WATCHMAN(TM) in a clopidogrel non-responder: A case for concern?

scientific article published on 11 November 2017

Thrombogenicity and central pulse pressure to enhance prediction of ischemic event occurrence in patients with established coronary artery disease: The MAGMA-ischemia score.

scientific article published on 20 November 2017

Thromboxane inhibition during concurrent therapy with low-dose aspirin and over-the-counter naproxen sodium

scientific article published on 2 December 2017

Ticagrelor With or Without Aspirin After PCI: The TWILIGHT Platelet Substudy

scientific article published on 01 February 2020

Ticagrelor alone vs. ticagrelor plus aspirin following percutaneous coronary intervention in patients with non-ST-segment elevation acute coronary syndromes: TWILIGHT-ACS

scientific article published on 01 October 2020

Ticagrelor for the treatment of arterial thrombosis

scientific article published on September 2010

Ticagrelor versus Clopidogrel in Peripheral Artery Disease

scientific article published on 01 April 2017

Ticagrelor with or without Aspirin in High-Risk Patients after PCI

scientific article published on 26 September 2019

Time dependence of clopidogrel loading effect: Platelet activation versus platelet aggregation ⬇️

scientific article published on August 20, 2011

Timing of Coronary Bypass Surgery in Patients Receiving Clopidogrel: The Role of VerifyNow.

scientific article

To stop or continue aspirin before aortocoronary bypass operations-do we have enough evidence to adequately guide us?

scientific article published on July 2016

Toward a therapeutic window for antiplatelet therapy in the elderly

scientific article published on 22 January 2012

Translational platelet research in patients with coronary artery disease: what are the major knowledge gaps?

scientific article published on 25 May 2012

Triple antithrombotic therapy with prasugrel in the stented patient: concern for more bleeding

scientific article published on 21 March 2013

Unravelling the smokers' paradox: cigarette smoking, high-risk coronary artery disease and enhanced clinical efficacy of oral P2Y₁₂ inhibitors

scientific article published on 20 February 2014

Update: Acute coronary syndromes (V). Personalized antiplatelet therapy

scientific article published on May 2014

Updated Expert Consensus Statement on Platelet Function and Genetic Testing for Guiding P2Y12 Receptor Inhibitor Treatment in Percutaneous Coronary Intervention

scientific article published on 12 June 2019

Updated evidence on intracoronary abciximab in ST-elevation myocardial infarction: a systematic review and meta-analysis of randomized clinical trials

scientific article published on January 2012

Usefulness of the VerifyNow P2Y12 assay to evaluate the antiplatelet effects of ticagrelor and clopidogrel therapies.

scientific article

Usefulness of thrombelastography platelet mapping assay to measure the antiplatelet effect of P2Y12receptor inhibitors and high on-treatment platelet reactivity ⬇️

scientific article published on May 30, 2012

Vascular risk levels affect the predictive value of platelet reactivity for the occurrence of MACE in patients on clopidogrel. Systematic review and meta-analysis of individual patient data

scientific article

Viscoelastic properties of clot formation and their clinical impact in East Asian versus Caucasian patients with stable coronary artery disease: a COMPARE-RACE analysis

scientific article published on 27 August 2020

Vorapaxar in the secondary prevention of atherothrombosis

scientific article

Vorapaxar: a novel protease-activated receptor-1 inhibitor ⬇️

scientific article published on 06 August 2011

We Need Further Studies for the Development of “Optimized Antiplatelet Therapy” Based on Ethnicity ⬇️

scientific article published on 01 July 2011

What is the best anticoagulant therapy during primary percutaneous coronary intervention for acute myocardial infarction?

scientific article published on 28 May 2015

What is the best measure of thrombotic risks--pretreatment platelet aggregation, clopidogrel responsiveness, or posttreatment platelet aggregation?

scientific article

What is the optimum adjunctive reperfusion strategy for primary percutaneous coronary intervention?

scientific article published on August 2013

[The role of clopidogrel in cardiovascular diseases].

scientific article

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