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Authors whose works are in public domain in at least one jurisdiction

List of works by W Ripley Ballou

A Monovalent Chimpanzee Adenovirus Ebola Vaccine Boosted with MVA

scientific article

A field trial to assess a blood-stage malaria vaccine

scientific article published on September 2011

A phase 3 trial of RTS,S/AS01 malaria vaccine in African infants

scientific article

A phase I safety and immunogenicity trial with the candidate malaria vaccine RTS,S/SBAS2 in semi-immune adults in The Gambia.

scientific article published in December 1999

A phase I/IIa safety, immunogenicity, and efficacy bridging randomized study of a two-dose regimen of liquid and lyophilized formulations of the candidate malaria vaccine RTS,S/AS02A in malaria-naïve adults

scientific article published on 30 May 2007

A randomized trial assessing the safety and immunogenicity of AS01 and AS02 adjuvanted RTS,S malaria vaccine candidates in children in Gabon

scientific article

Activity of human volunteer sera to candidate Plasmodium falciparum circumsporozoite protein vaccines in the inhibition of sporozoite invasion assay of human hepatoma cells and hepatocytes.

scientific article published in May 1990

Acute Exacerbation and Respiratory InfectionS in COPD (AERIS): protocol for a prospective, observational cohort study

scientific article published on 07 March 2014

Ad35.CS.01-RTS,S/AS01 Heterologous Prime Boost Vaccine Efficacy against Sporozoite Challenge in Healthy Malaria-Naïve Adults

scientific article published on 6 July 2015

American cutaneous leishmaniasis: a comparison of three sodium stibogluconate treatment schedules

scientific article published on 01 September 1985

Azithromycin prophylaxis against a chloroquine-resistant strain of Plasmodium falciparum

scientific article published on June 1994

Blood stage malaria vaccine eliciting high antigen-specific antibody concentrations confers no protection to young children in Western Kenya

scientific article

Correction: Safety of the Malaria Vaccine Candidate, RTS,S/AS01E in 5 to 17 Month Old Kenyan and Tanzanian Children.

scientific article

Cultivation of the exoerythrocytic stage of Plasmodium berghei in primary cultures of mouse hepatocytes and continuous mouse cell lines

scientific article published on 01 September 1989

Design of a phase III multicenter trial to evaluate the efficacy of the RTS,S/AS01 malaria vaccine in children across diverse transmission settings in Africa

scientific article

Development and pre-clinical analysis of a Plasmodium falciparum Merozoite Surface Protein-1(42) malaria vaccine

scientific article published in May 2003

Development of a recombinant FimCH vaccine for urinary tract infections.

scientific article published on January 2003

Devices for rapid diagnosis of Malaria: evaluation of prototype assays that detect Plasmodium falciparum histidine-rich protein 2 and a Plasmodium vivax-specific antigen

scientific article

Duration of protection with RTS,S/AS02A malaria vaccine in prevention of Plasmodium falciparum disease in Mozambican children: single-blind extended follow-up of a randomised controlled trial

scientific article published on December 2005

Efficacy of RTS,S/AS01E malaria vaccine and exploratory analysis on anti-circumsporozoite antibody titres and protection in children aged 5-17 months in Kenya and Tanzania: a randomised controlled trial

scientific article published on 13 January 2011

Efficacy of RTS,S/AS01E vaccine against malaria in children 5 to 17 months of age

scientific article

Efficacy of RTS,S/AS02 malaria vaccine against Plasmodium falciparum infection in semi-immune adult men in The Gambia: a randomised trial

scientific article published in December 2001

Efficacy of recombinant circumsporozoite protein vaccine regimens against experimental Plasmodium falciparum malaria

scientific article published on 24 January 2001

Efficacy of the RTS,S/AS02A vaccine against Plasmodium falciparum infection and disease in young African children: randomised controlled trial

scientific article

Evaluation of RTS,S/AS02A and RTS,S/AS01B in adults in a high malaria transmission area.

scientific article

Evaluation of the immune response to RTS,S/AS01 and RTS,S/AS02 adjuvanted vaccines: randomized, double-blind study in malaria-naïve adults

scientific article published on January 2014

Evaluation of the safety and immunogenicity of two antigen concentrations of the Mtb72F/AS02(A) candidate tuberculosis vaccine in purified protein derivative-negative adults

scientific article

Evaluation of two formulations of adjuvanted RTS, S malaria vaccine in children aged 3 to 5 years living in a malaria-endemic region of Mozambique: a Phase I/IIb randomized double-blind bridging trial

scientific article published on 26 March 2007

Expression of genes associated with immunoproteasome processing of major histocompatibility complex peptides is indicative of protection with adjuvanted RTS,S malaria vaccine.

scientific article published in February 2010

Extended safety, immunogenicity and efficacy of a blood-stage malaria vaccine in malian children: 24-month follow-up of a randomized, double-blinded phase 2 trial

scientific article

Field trials of an asexual blood stage malaria vaccine: studies of the synthetic peptide polymer SPf66 in Thailand and the analytic plan for a phase IIb efficacy study.

scientific article published in January 1995

First results of phase 3 trial of RTS,S/AS01 malaria vaccine in African children

scientific article

Five-year safety and immunogenicity of GlaxoSmithKline's candidate malaria vaccine RTS,S/AS02 following administration to semi-immune adult men living in a malaria-endemic region of The Gambia

scientific article published on 22 April 2009

Follow-up of Gambian children recruited to a pilot safety and immunogenicity study of the malaria vaccine SPf66.

scientific article

Four year immunogenicity of the RTS,S/AS02(A) malaria vaccine in Mozambican children during a phase IIb trial

scientific article published on 7 April 2011

Fractional Third and Fourth Dose of RTS,S/AS01 Malaria Candidate Vaccine: A Phase 2a Controlled Human Malaria Parasite Infection and Immunogenicity Study

scientific article

Frequent transmission of HTLV-III among spouses of patients with AIDS-related complex and AIDS.

scientific article

Heterologous prime-boost immunization in rhesus macaques by two, optimally spaced particle-mediated epidermal deliveries of Plasmodium falciparum circumsporozoite protein-encoding DNA, followed by intramuscular RTS,S/AS02A.

scientific article published on 6 March 2006

Immunization against the murine malaria parasite Plasmodium yoelii using a recombinant protein with adjuvants developed for clinical use.

scientific article published in October 1997

Immunization of Aotus nancymai with recombinant C terminus of Plasmodium falciparum merozoite surface protein 1 in liposomes and alum adjuvant does not induce protection against a challenge infection

scientific article published on September 1996

Immunization of Saimiri sciureus boliviensis with recombinant vaccines based on the circumsporozoite protein of Plasmodium vivax.

scientific article published in May 1989

Immunological mechanisms underlying protection mediated by RTS,S: a review of the available data

scientific article

Impact of RTS,S/AS02(A) and RTS,S/AS01(B) on genotypes of P. falciparum in adults participating in a malaria vaccine clinical trial

scientific article

Induction of T helper type 1 and 2 responses to 19-kilodalton merozoite surface protein 1 in vaccinated healthy volunteers and adults naturally exposed to malaria

scientific article

Insights into long-lasting protection induced by RTS,S/AS02A malaria vaccine: further results from a phase IIb trial in Mozambican children

scientific article

Long-term safety and efficacy of the RTS,S/AS02A malaria vaccine in Mozambican children

scientific article published on August 2009

Malaria transmitted to humans by mosquitoes infected from cultured plasmodium falciparum

scientific article published in January 1986

Malaria treatment with atovaquone-proguanil in malaria-immune adults: implications for malaria intervention trials and for pre-exposure prophylaxis of malaria

scientific article published on 11 February 2008

Malaria vaccines in development

scientific article

Non-CS pre-erythrocytic protective antigens

scientific article published on 01 August 1990

Obstacles to the development of a safe and effective attenuated pre-erythrocytic stage malaria vaccine

scientific article published on 21 February 2007

Phase 1 safety and immunogenicity trial of malaria vaccine RTS,S/AS02A in adults in a hyperendemic region of western Kenya

scientific article published in July 2006

Phase 1/2a Trial of Plasmodium vivax Malaria Vaccine Candidate VMP001/AS01B in Malaria-Naive Adults: Safety, Immunogenicity, and Efficacy

scientific article

Phase 1/2a study of the malaria vaccine candidate apical membrane antigen-1 (AMA-1) administered in adjuvant system AS01B or AS02A.

scientific article

Phase 2a trial of 0, 1, and 3 month and 0, 7, and 28 day immunization schedules of malaria vaccine RTS,S/AS02 in malaria-naïve adults at the Walter Reed Army Institute of Research

scientific article published on 13 March 2008

Phase I dose escalation safety and immunogenicity trial of Plasmodium falciparum apical membrane protein (AMA-1) FMP2.1, adjuvanted with AS02A, in malaria-naïve adults at the Walter Reed Army Institute of Research.

scientific article published on 26 March 2007

Phase I safety and immunogenicity testing of clinical lots of the synthetic Plasmodium falciparum vaccine SPf66 produced under good manufacturing procedure conditions in the United States.

scientific article published in July 1996

Phase I trial of the SPf66 malaria vaccine in a malaria-experienced population in Southeast Asia

scientific article published in May 1997

Phase I/IIa safety, immunogenicity, and efficacy trial of NYVAC-Pf7, a pox-vectored, multiantigen, multistage vaccine candidate for Plasmodium falciparum malaria.

scientific article published in June 1998

Plasmodium falciparum malaria vaccines in development

scientific article published on March 2008

Plasmodium falciparum-specific cellular immune responses after immunization with the RTS,S/AS02D candidate malaria vaccine in infants living in an area of high endemicity in Mozambique

scientific article published on 03 August 2009

Plasmodium falciparum: elicitation by peptides and recombinant circumsporozoite proteins of circulating mouse antibodies inhibiting sporozoite invasion of hepatoma cells

scientific article published on 01 June 1987

Pre-clinical evaluation of the malaria vaccine candidate P. falciparum MSP1(42) formulated with novel adjuvants or with alum

scientific article published in September 2004

Pre-erythrocytic malaria vaccines to prevent Plasmodium falciparum malaria.

scientific article

Predicting RTS,S Vaccine-Mediated Protection from Transcriptomes in a Malaria-Challenge Clinical Trial

scientific article published on 23 May 2017

Protection against tetrodotoxin and saxitoxin intoxication by a cross-protective rabbit anti-tetrodotoxin antiserum

scientific article published in January 1991

Protection of humans against malaria by immunization with radiation-attenuated Plasmodium falciparum sporozoites

scientific article (publication date: 15 April 2002)

Protective immunity induced with malaria vaccine, RTS,S, is linked to Plasmodium falciparum circumsporozoite protein-specific CD4+ and CD8+ T cells producing IFN-gamma

scientific article published in December 2003

RTS,S/AS02A malaria vaccine does not induce parasite CSP T cell epitope selection and reduces multiplicity of infection

scientific article published on 19 May 2006

Randomised double-blind placebo-controlled trial of SPf66 malaria vaccine in children in northwestern Thailand. Shoklo SPf66 Malaria Vaccine Trial Group

scientific article

Randomized controlled trial of RTS,S/AS02D and RTS,S/AS01E malaria candidate vaccines given according to different schedules in Ghanaian children

scientific article published on 2 October 2009

Randomized, controlled trial of the long term safety, immunogenicity and efficacy of RTS,S/AS02D malaria vaccine in infants living in a malaria-endemic region ⬇️

scientific article published on January 8, 2013

Randomized, double-blind, phase 2a trial of falciparum malaria vaccines RTS,S/AS01B and RTS,S/AS02A in malaria-naive adults: safety, efficacy, and immunologic associates of protection

scientific article

Recombinant Liver Stage Antigen-1 (LSA-1) formulated with AS01 or AS02 is safe, elicits high titer antibody and induces IFN-gamma/IL-2 CD4+ T cells but does not protect against experimental Plasmodium falciparum infection

scientific article published on 6 September 2009

Reply from stoute et Al

scientific article published on 01 February 1998

Response of Plasmodium vivax variants to chloroquine as determined by microscopy and quantitative polymerase chain reaction.

scientific article published on October 1993

Results from tandem Phase 1 studies evaluating the safety, reactogenicity and immunogenicity of the vaccine candidate antigen Plasmodium falciparum FVO merozoite surface protein-1 (MSP1(42)) administered intramuscularly with adjuvant system AS01.

scientific article published on 23 January 2013

SPf66 malaria vaccine is safe and immunogenic in malaria naive adults in Thailand.

scientific article published in September 1997

Safety and efficacy of a recombinant DNA Plasmodium falciparum sporozoite vaccine

scientific article published in June 1987

Safety and efficacy of high-dose sodium stibogluconate therapy of American cutaneous leishmaniasis

scientific article published in July 1987

Safety and immunogenicity of RTS,S/AS02D malaria vaccine in infants

scientific article

Safety and immunogenicity of a chimpanzee adenovirus-vectored Ebola vaccine in healthy adults: a randomised, double-blind, placebo-controlled, dose-finding, phase 1/2a study

scientific article

Safety and immunogenicity of a recombinant Plasmodium falciparum AMA1 malaria vaccine adjuvanted with Alhydrogel, Montanide ISA 720 or AS02.

scientific article

Safety and immunogenicity of a recombinant parvovirus B19 vaccine formulated with MF59C.1.

scientific article

Safety and immunogenicity of an AMA1 malaria vaccine in Malian children: results of a phase 1 randomized controlled trial

scientific article

Safety and immunogenicity of rts,s+trap malaria vaccine, formulated in the as02a adjuvant system, in infant rhesus monkeys.

scientific article

Safety and reactogenicity of an MSP-1 malaria vaccine candidate: a randomized phase Ib dose-escalation trial in Kenyan children

scientific article published on 24 November 2006

Safety and reactogenicity profile of an adjuvanted H5N1 pandemic candidate vaccine in adults within a phase III safety trial.

scientific article

Safety of the RTS,S/AS02A malaria vaccine in Mozambican children during a Phase IIb trial

scientific article

Safety of the RTS,S/AS02D candidate malaria vaccine in infants living in a highly endemic area of Mozambique: a double blind randomised controlled phase I/IIb trial

scientific article

Safety of the malaria vaccine candidate, RTS,S/AS01E in 5 to 17 month old Kenyan and Tanzanian Children

scientific article (publication date: 29 November 2010)

Safety, immunogenicity and duration of protection of the RTS,S/AS02(D) malaria vaccine: one year follow-up of a randomized controlled phase I/IIb trial

scientific article (publication date: 4 November 2010)

Sequential Phase 1 and Phase 2 randomized, controlled trials of the safety, immunogenicity and efficacy of combined pre-erythrocytic vaccine antigens RTS,S and TRAP formulated with AS02 Adjuvant System in healthy, malaria naïve adults

scientific article published on 18 June 2014

Strain-specific Plasmodium falciparum growth inhibition among Malian children immunized with a blood-stage malaria vaccine

scientific article

Strain-specific Plasmodium falciparum multifunctional CD4(+) T cell cytokine expression in Malian children immunized with the FMP2.1/AS02A vaccine candidate

scientific article published on 14 April 2016

Systems analysis of protective immune responses to RTS,S malaria vaccination in humans

scientific article published on 13 February 2017

The candidate tuberculosis vaccine Mtb72F/AS02 in PPD positive adults: A randomized controlled phase I/II study ⬇️

scientific article published on 05 December 2012

The candidate tuberculosis vaccine Mtb72F/AS02A: Tolerability and immunogenicity in humans

scientific article published on 27 July 2009

The development of molecular vaccines against malaria sporozoites

scientific article published on January 1989

The development of the RTS,S malaria vaccine candidate: challenges and lessons

scientific article published on September 2009

Towards an RTS,S-based, multi-stage, multi-antigen vaccine against falciparum malaria: progress at the Walter Reed Army Institute of Research.

scientific article

Two decades of commitment to malaria vaccine development: GlaxoSmithKline Biologicals

scientific article published on December 2007

Update on the clinical development of candidate malaria vaccines.

scientific article published in August 2004

Use of ChAd3-EBO-Z Ebola virus vaccine in Malian and US adults, and boosting of Malian adults with MVA-BN-Filo: a phase 1, single-blind, randomised trial, a phase 1b, open-label and double-blind, dose-escalation trial, and a nested, randomised, doub

scientific article

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