List of works by Alapakkam P Sampath

ATP consumption by mammalian rod photoreceptors in darkness and in light.

scientific article published on 11 December 2008

Activation of Rod Input in a Model of Retinal Degeneration Reverses Retinal Remodeling and Induces Formation of Functional Synapses and Recovery of Visual Signaling in the Adult Retina

scientific article published on 08 July 2019

Apoptosis regulates ipRGC spacing necessary for rods and cones to drive circadian photoentrainment.

scientific article published on February 2013

Behavioural and physiological limits to vision in mammals

scientific article published on April 2017

Bleached pigment produces a maintained decrease in outer segment Ca2+ in salamander rods

scientific article published in January 1998

Changes in ganglion cell physiology during retinal degeneration influence excitability by prosthetic electrodes

scientific article published on 23 February 2016

Cones and Cone Pathways Remain Functional in Advanced Retinal Degeneration

preprint of a scholarly article

Cones and cone pathways remain functional in advanced retinal degeneration

scientific article published on 24 April 2023

Controlling the gain of rod-mediated signals in the Mammalian retina

scientific article published on 01 April 2006

Coordinated control of sensitivity by two splice variants of Gα(o) in retinal ON bipolar cells

scientific article

Dark-adapted response threshold of OFF ganglion cells is not set by OFF bipolar cells in the mouse retina

scientific article

Detection of single photons by toad and mouse rods.

scientific article

Diminished Cone Sensitivity in cpfl3 Mice Is Caused by Defective Transducin Signaling

scientific article published on 01 April 2020

Elevated energy requirement of cone photoreceptors

scientific article published on 27 July 2020

Energy Shortage in Human and Mouse Models of SLC4A11-Associated Corneal Endothelial Dystrophies

scientific article published on 01 July 2020

Exchange of Cone for Rod Phosphodiesterase 6 Catalytic Subunits in Rod Photoreceptors Mimics in Part Features of Light Adaptation.

scientific article published on June 2015

Flow of energy in the outer retina in darkness and in light.

scientific article

Functional comparison of rod and cone Gα(t) on the regulation of light sensitivity

scientific article published on 3 January 2013

Functional properties of synaptic transmission in primary sense organs

scientific article

Investigation of the functional impact of CHED- and FECD4-associated SLC4A11 mutations in human corneal endothelial cells

scholarly article

LRIT1 Modulates Adaptive Changes in Synaptic Communication of Cone Photoreceptors.

scientific article published in March 2018

LRR-ning the Rules: Synapse Organization in the Primary Rod Pathway

scientific article published on 01 March 2020

Late gene therapy limits the restoration of retinal function in a mouse model of retinitis pigmentosa

scientific article published on 12 December 2023

Late gene therapy limits the restoration of retinal function in a mouse model of retinitis pigmentosa

preprint article published on 8 April 2023

Light-Driven Regeneration of Cone Visual Pigments through a Mechanism Involving RGR Opsin in Müller Glial Cells

scientific article published on 02 May 2019

Light-dependent changes in outer segment free-Ca2+ concentration in salamander cone photoreceptors.

scientific article

Measurement of cytoplasmic calcium concentration in the rods of wild-type and transducin knock-out mice

scientific article

Mechanism for Selective Synaptic Wiring of Rod Photoreceptors into the Retinal Circuitry and Its Role in Vision

scientific article published on September 2015

Membrane conductances of mouse cone photoreceptors

scientific article published on 01 March 2020

Metabolic constraints on the recovery of sensitivity after visual pigment bleaching in retinal rods.

scientific article published on 17 August 2009

Molecular mechanism of spontaneous pigment activation in retinal cones

scientific article

Optimal processing of photoreceptor signals is required to maximize behavioural sensitivity

scientific article published on 19 April 2010

Optimization of single-photon response transmission at the rod-to-rod bipolar synapse

scientific article published on August 2007

Patch Clamp Recordings from Mouse Retinal Neurons in a Dark-adapted Slice Preparation ⬇️

scientific article published on September 12, 2010

Perspectives on: information coding in mammalian sensory physiology

scientific article

Photopigment quenching is Ca2+ dependent and controls response duration in salamander L-cone photoreceptors

scientific article

Physiological response of mouse retinal ganglion cells to electrical stimulation: effect of soma size

scientific article

Physiological response of normal and RD mouse retinal ganglion cells to electrical stimulation

scientific article published in January 2012

Recoverin improves rod-mediated vision by enhancing signal transmission in the mouse retina

scientific article published in May 2005

Regulators of G protein signaling RGS7 and RGS11 determine the onset of the light response in ON bipolar neurons.

scientific article

Retina-specific GTPase accelerator RGS11/G beta 5S/R9AP is a constitutive heterotrimer selectively targeted to mGluR6 in ON-bipolar neurons

scientific article published on July 2009

Retinal processing near absolute threshold: from behavior to mechanism.

scientific article

Robust cone-mediated signaling persists late into rod photoreceptor degeneration

scientific article published on 30 August 2022

Robust cone-mediated signaling persists late into rod photoreceptor degeneration

preprint of a scientific article published on 28 April 2022

Rod Photoreceptors Avoid Saturation in Bright Light by the Movement of the G Protein Transducin

scientific article published on 16 February 2021

Rod and cone interactions in the retina.

scientific article published on 23 May 2018

Rod photoreceptors drive circadian photoentrainment across a wide range of light intensities

scientific article

Selective transmission of single photon responses by saturation at the rod-to-rod bipolar synapse

scientific article published in February 2004

Sensitivity and kinetics of signal transmission at the first visual synapse differentially impact visually-guided behavior

scientific article published on 16 April 2015

Separate ON and OFF pathways in vertebrate vision first arose during the Cambrian

scientific article published on 01 June 2020

Setting the absolute threshold of vision

scientific article

Targeting of RGS7/Gbeta5 to the dendritic tips of ON-bipolar cells is independent of its association with membrane anchor R7BP.

scientific article

The Auxiliary Calcium Channel Subunit α2δ4 Is Required for Axonal Elaboration, Synaptic Transmission, and Wiring of Rod Photoreceptors

scientific article published on 23 February 2017

The Transduction Cascade in Retinal ON-Bipolar Cells: Signal Processing and Disease

scientific article published on 17 July 2017

Transducin translocation contributes to rod survival and enhances synaptic transmission from rods to rod bipolar cells

scientific article published on 08 July 2013

Virally delivered channelrhodopsin-2 safely and effectively restores visual function in multiple mouse models of blindness

scientific article published on 19 April 2011

Visual threshold is set by linear and nonlinear mechanisms in the retina that mitigate noise: how neural circuits in the retina improve the signal-to-noise ratio of the single-photon response

scientific article

Voltage-clamp recordings of light responses from wild-type and mutant mouse cone photoreceptors

scientific article published on 27 September 2019

Voltage-sensitive conductances increase the sensitivity of rod photoresponses following pigment bleaching.

scientific article published on 7 February 2017

Why are rods more sensitive than cones?

scientific article

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