List of works - Shuh Narumiya

A role for mDia, a Rho-regulated actin nucleator, in tangential migration of interneuron precursors

scientific article published on 15 January 2012

A sphingosine-1-phosphate receptor type 1 agonist, ASP4058, suppresses intracranial aneurysm through promoting endothelial integrity and blocking macrophage transmigration

scientific article

Actin polymerization-driven molecular movement of mDia1 in living cells

scientific article published in March 2004

Adhesion of platelets through thromboxane A₂ receptor signaling facilitates liver repair during acute chemical-induced hepatotoxicity

scientific article

An essential role of Cdc42-like GTPases in mitosis of HeLa cells

scientific article published on 11 May 2006

Anti-inflammatory role of PGD 2 in acute lung inflammation and therapeutic application of its signal enhancement ⬇️

scientific article published on March 11, 2013

Aquaporin-3 potentiates allergic airway inflammation in ovalbumin-induced murine asthma

scientific article published on 11 May 2016

Arachidonic acid and prostacyclin signaling promote adipose tissue development: a human health concern?

scientific article

Augmented cardiac hypertrophy in response to pressure overload in mice lacking the prostaglandin I2 receptor

scientific article published on 27 June 2005

Bone marrow-derived EP3-expressing stromal cells enhance tumor-associated angiogenesis and tumor growth

scientific article published on 24 March 2009

CCAAT/enhancer-binding protein delta/miR135a/thrombospondin 1 axis mediates PGE2-induced angiogenesis in Alzheimer's disease

scientific article published on 4 December 2014

Cdc42 and Rac family GTPases regulate mode and speed but not direction of primary fibroblast migration during platelet-derived growth factor-dependent chemotaxis

scientific article

Central PGE2exhibits anxiolytic-like activity via EP1and EP4receptors in a manner dependent on serotonin 5-HT1A, dopamine D1and GABAAreceptors ⬇️

scientific article published on June 17, 2011

Characteristics of thermoregulatory and febrile responses in mice deficient in prostaglandin EP1 and EP3 receptors

scientific article published on July 2003

Cigarette Smoke Extract Inhibits Platelet Aggregation by Suppressing Cyclooxygenase Activity

scientific article published on 01 July 2017

Constitutive Activation of Integrin α9 Augments Self-Directed Hyperplastic and Proinflammatory Properties of Fibroblast-like Synoviocytes of Rheumatoid Arthritis

scientific article published on 16 October 2017

Conversion of antigen-specific effector/memory T cells into Foxp3-expressing Treg cells by inhibition of CDK8/19

scientific article published on 01 October 2019

Critical role of TNF-alpha-TNFR1 signaling in intracranial aneurysm formation

scientific article published on 31 March 2014

Crystal structure of the endogenous agonist-bound prostanoid receptor EP3

scientific article published on 03 December 2018

Deficiency of mDia, an actin nucleator, disrupts integrity of neuroepithelium and causes periventricular dysplasia.

scientific article

Definition of Prostaglandin E2-EP2 Signals in the Colon Tumor Microenvironment That Amplify Inflammation and Tumor Growth

scientific article

Disruption of Actin Dynamics Regulated by Rho Effector mDia1 Attenuates Pressure Overload-Induced Cardiac Hypertrophic Responses and Exacerbates Dysfunction

scientific article published on 09 July 2020

Dual functions of prostaglandin D2 in murine contact hypersensitivity via DP and CRTH2.

scientific article

Dual roles of PGE2-EP4 signaling in mouse experimental autoimmune encephalomyelitis

scientific article

EP2and EP4receptors on muscularis resident macrophages mediate LPS-induced intestinal dysmotility via iNOS upregulation through cAMP/ERK signals ⬇️

scientific article published on December 8, 2011

EP3 signaling in dendritic cells promotes liver repair by inducing IL-13-mediated macrophage differentiation in mice

scientific article published on 28 February 2020

Effects of the prostanoids on the proliferation or hypertrophy of cultured murine aortic smooth muscle cells

scientific article published in June 2002

Emerging roles of prostanoids in T cell‐mediated immunity ⬇️

scientific article published on August 1, 2010

EphA4-dependent axon retraction and midline localization of Ephrin-B3 are disrupted in the spinal cord of mice lacking mDia1 and mDia3 in combination.

scientific article published on 25 July 2013

Epistatic interaction between Toll-like receptor 3 (TLR3) and prostaglandin E receptor 3 (PTGER3) genes

scientific article published on 14 March 2012

Erratum: Prostaglandin E2 promotes Th1 differentiation via synergistic amplification of IL-12 signalling by cAMP and PI3-kinase

scientific article published in Nature Communications

Exacerbation of intracranial aneurysm and aortic dissection in hypertensive rat treated with the prostaglandin F-receptor antagonist AS604872.

scientific article published on 23 October 2014

Expression of prostaglandin F receptor in scleral and subconjunctival tissue ⬇️

scientific article published on May 11, 2012

Expression of the prostaglandin F receptor (FP) gene along the mouse genitourinary tract

scientific article published on 11 March 2003

Expression profiling of cumulus cells reveals functional changes during ovulation and central roles of prostaglandin EP2 receptor in cAMP signaling

scientific article published on 20 April 2010

F- and G-actin homeostasis regulates mechanosensitive actin nucleation by formins ⬇️

scientific article published on March 3, 2013

Fever, inflammation, pain and beyond: prostanoid receptor research during these 25 years ⬇️

scientific article published on March 1, 2011

Functional evidence for interaction between prostaglandin EP3 and kappa-opioid receptor pathways in tactile pain induced by human immunodeficiency virus type-1 (HIV-1) glycoprotein gp120.

scientific article

G-CSF-induced sympathetic tone provokes fever and primes antimobilizing functions of neutrophils via PGE2.

scientific article published on 8 November 2016

G-actin regulates rapid induction of actin nucleation by mDia1 to restore cellular actin polymers

scientific article published on 30 September 2008

Genetic and pharmacological inhibition of Rho-associated kinase II enhances adipogenesis.

scientific article published on 6 August 2007

Hepatic stellate cells relay inflammation signaling from sinusoids to parenchyma in mouse models of immune-mediated hepatitis

scientific article published on 30 September 2015

Host prostaglandin E(2)-EP3 signaling regulates tumor-associated angiogenesis and tumor growth

scientific article

Host prostaglandin EP3 receptor signaling relevant to tumor-associated lymphangiogenesis

scientific article

Identification of EP4 as a potential target for the treatment of castration-resistant prostate cancer using a novel xenograft model

scientific article

Impaired adrenocorticotropic hormone response to bacterial endotoxin in mice deficient in prostaglandin E receptor EP1 and EP3 subtypes

scientific article

Impaired vascular remodeling in the yolk sac of embryos deficient in ROCK-I and ROCK-II ⬇️

scientific article published on September 5, 2011

Improvement of cognitive function in Alzheimer's disease model mice by genetic and pharmacological inhibition of the EP(4) receptor

scientific article published on 23 January 2012

Inactivation of Rho GTPases with Clostridium difficile toxin B impairs centrosomal activation of Aurora-A in G2/M transition of HeLa cells

scientific article published on 18 July 2007

Inhibition of microsomal prostaglandin E synthase-1 facilitates liver repair after hepatic injury in mice

scientific article published on 16 February 2018

Involvement of cyclooxygenase-2 and EP3 prostaglandin receptor in acute herpetic but not postherpetic pain in mice

scientific article

Involvement of prostaglandin E receptor subtype EP(4) in colon carcinogenesis.

scientific article

Involvement of prostaglandin E2 in production of amyloid-beta peptides both in vitro and in vivo

scientific article published on 2 September 2007

LPA Induces Keratinocyte Differentiation and Promotes Skin Barrier Function through the LPAR1/LPAR5-RHO-ROCK-SRF Axis

scientific article published on 14 November 2018

Ligand binding to human prostaglandin E receptor EP4 at the lipid-bilayer interface

scientific article published on 03 December 2018

Lipocalin-type prostaglandin D synthase regulates light-induced phase advance of the central circadian rhythm in mice

scientific article published on 08 October 2020

Loss of a Rho-regulated actin nucleator, mDia2, impairs cytokinesis during mouse fetal erythropoiesis

scientific article published on 14 November 2013

Macrophage Imaging of Cerebral Aneurysms with Ferumoxytol: an Exploratory Study in an Animal Model and in Patients.

scientific article published on 31 July 2017

Migration without a clutch

scientific article published on 01 December 2009

Molecular identification and characterization of a family of kinases with homology to Ca2+/calmodulin-dependent protein kinases I/IV

scientific journal article

Multiple spatiotemporal modes of actin reorganization by NMDA receptors and voltage-gated Ca2+ channels

scientific article

Opposing immunomodulatory roles of prostaglandin D2 during the progression of skin inflammation

scientific article

Orally administered rubiscolin-6, a δ opioid peptide derived from Rubisco, stimulates food intake via leptomeningeal lipocallin-type prostaglandin D synthase in mice

scientific article

PS144. Dopamine D1 receptor in the medial prefrontal cortex mediates behavioral resilience under stress in mice.

scientific article published on 27 May 2016

PS205. Innate immune molecules activate microglia in mPFC to induce neuronal and emotional changes in mice.

scientific article published on 27 May 2016

Pathophysiological roles of the prostanoids in the cardiovascular system: studies using mice deficient in prostanoid receptors

scientific article published in November 2003

Prostacyclin-IP signaling and prostaglandin E2-EP2/EP4 signaling both mediate joint inflammation in mouse collagen-induced arthritis

scientific article

Prostaglandin D 2 -DP Signaling Promotes Endothelial Barrier Function via the cAMP/PKA/Tiam1/Rac1 Pathway ⬇️

scientific article published on January 10, 2013

Prostaglandin D2 protects neonatal mouse brain from hypoxic ischemic injury.

scientific article

Prostaglandin D2-mediated microglia/astrocyte interaction enhances astrogliosis and demyelination in twitcher.

scientific article

Prostaglandin E receptor EP1 controls impulsive behavior under stress.

scientific article

Prostaglandin E receptor EP1 enhances GABA-mediated inhibition of dopaminergic neurons in the substantia nigra pars compacta and regulates dopamine level in the dorsal striatum

scientific article published on 10 December 2009

Prostaglandin E receptor EP1 forms a complex with dopamine D1 receptor and directs D1-induced cAMP production to adenylyl cyclase 7 through mobilizing G(βγ) subunits in human embryonic kidney 293T cells.

scientific article published on 10 July 2013

Prostaglandin E receptor EP3 deficiency modifies tumor outcome in mouse two-stage skin carcinogenesis

scientific article published on 28 July 2005

Prostaglandin E receptor EP4 stimulates lymphangiogenesis to promote mucosal healing during DSS-induced colitis

scientific article published on 21 May 2020

Prostaglandin E receptor subtype EP(1) deficiency inhibits colon cancer development

scientific article

Prostaglandin E receptor subtype EP3 in conjunctival epithelium regulates late-phase reaction of experimental allergic conjunctivitis

scientific article

Prostaglandin E receptors

scientific article published on 28 February 2007

Prostaglandin E(2) regulates murine hematopoietic stem/progenitor cells directly via EP4 receptor and indirectly through mesenchymal progenitor cells.

scientific article published on 11 January 2013

Prostaglandin E2 (PGE2)-EP2 signaling negatively regulates murine atopic dermatitis-like skin inflammation by suppressing thymic stromal lymphopoietin expression

scientific article published on 11 July 2019

Prostaglandin E2 acts on EP1 receptor and amplifies both dopamine D1 and D2 receptor signaling in the striatum.

scientific article published in November 2007

Prostaglandin E2 promotes Th1 differentiation via synergistic amplification of IL-12 signalling by cAMP and PI3-kinase ⬇️

scientific article published on January 1, 2013

Prostaglandin E2 protects the heart from ischemia-reperfusion injury via its receptor subtype EP4.

scientific article

Prostaglandin E2 stimulates adaptive IL-22 production and promotes allergic contact dermatitis

scientific article published on 2 June 2017

Prostaglandin E2 stimulates the production of amyloid-beta peptides through internalization of the EP4 receptor.

scientific article published on 30 April 2009

Prostaglandin E2, an immunoactivator.

scientific article published on 06 January 2010

Prostaglandin E2-EP2-NF-κB signaling in macrophages as a potential therapeutic target for intracranial aneurysms.

scientific article published on 7 February 2017

Prostaglandin E2-EP4 signaling persistently amplifies CD40-mediated induction of IL-23 p19 expression through canonical and non-canonical NF-κB pathways.

scientific article published on 20 July 2015

Prostaglandin E2-EP4 signaling promotes immune inflammation through Th1 cell differentiation and Th17 cell expansion

scientific journal article

Prostaglandin E2-Mediated Attenuation of Mesocortical Dopaminergic Pathway Is Critical for Susceptibility to Repeated Social Defeat Stress in Mice ⬇️

scientific article published on March 21, 2012

Prostaglandin E2-prostaglandin E receptor subtype 4 (EP4) signaling mediates UV irradiation-induced systemic immunosuppression

scientific article

Prostaglandin E₂ constrains systemic inflammation through an innate lymphoid cell-IL-22 axis

scientific article published on March 2016

Prostaglandin F(2alpha) receptor signaling facilitates bleomycin-induced pulmonary fibrosis independently of transforming growth factor-beta

scientific article published on 29 November 2009

Prostaglandin F2α Facilitates Platelet Activation by Acting on Prostaglandin E2 Receptor Subtype EP3 and Thromboxane A2 Receptor TP in Mice

scientific article published on 26 May 2019

Prostaglandin I2 plays a key role in zymosan-induced mouse pleurisy

scientific article published on 6 February 2008

Prostaglandin I2 promotes recruitment of endothelial progenitor cells and limits vascular remodeling.

scientific article published on 10 December 2009

Prostaglandin I2 suppresses the development of diet-induced nonalcoholic steatohepatitis in mice.

scientific article

Prostaglandin receptors EP2, EP3, and IP mediate exudate formation in carrageenin-induced mouse pleurisy

scientific article

Prostaglandin-cytokine crosstalk in chronic inflammation

scientific article published on 18 December 2018

Prostanoid receptors: structures, properties, and functions

scientific article (publication date: October 1999)

Protection of atherogenesis in thromboxane A2 receptor-deficient mice is not associated with thromboxane A2 receptor in bone marrow-derived cells

scientific article published on 02 November 2006

RNA sequencing analysis revealed the induction of CCL3 expression in human intracranial aneurysms

scientific article published on 17 July 2019

ROCK and mDia1 antagonize in Rho-dependent Rac activation in Swiss 3T3 fibroblasts

scientific article published on 20 May 2002

ROCK-I and ROCK-II cooperatively regulate closure of eyelid and ventral body wall in mouse embryo

scientific article published in August 2005

ROCK-I regulates closure of the eyelids and ventral body wall by inducing assembly of actomyosin bundles

scientific article

Real-time Imaging of an Experimental Intracranial Aneurysm in Rats

scientific article published on 15 December 2018

Repeated social defeat stress impairs attentional set shifting irrespective of social avoidance and increases female preference associated with heightened anxiety.

scientific article published on 11 July 2018

Rho and anillin-dependent control of mDia2 localization and function in cytokinesis

scientific article published on 21 July 2010

Rho signaling research: history, current status and future directions.

scientific article

Rho signaling, ROCK and mDia1, in transformation, metastasis and invasion

scientific article published on June 2009

RhoA/Rho kinase signaling in the cumulus mediates extracellular matrix assembly

scientific article

Role of PGE-type receptor 4 in auditory function and noise-induced hearing loss in mice ⬇️

scientific article published on December 16, 2011

Roles of Toll-like receptor 2/4, monoacylglycerol lipase, and cyclooxygenase in social defeat stress-induced prostaglandin E2 synthesis in the brain and their behavioral relevance

scientific article published on 26 November 2019

Roles of prostaglandin E receptors in stress responses

scientific article

Roles of prostaglandin E2-EP1 receptor signaling in regulation of gastric motor activity and emptying ⬇️

scientific article published on August 26, 2010

Roles of prostaglandin E2-EP3/EP4 receptor signaling in the enhancement of lymphangiogenesis during fibroblast growth factor-2-induced granulation formation.

scientific article

Roles of prostanoids in the pathogenesis of cardiovascular diseases: Novel insights from knockout mouse studies ⬇️

scientific article published on February 1, 2011

Roles of thromboxane A(2) and prostacyclin in the development of atherosclerosis in apoE-deficient mice

scientific article published on September 2004

Rotational Movement of the Formin mDia1 Along the Double Helical Strand of an Actin Filament ⬇️

scientific article published on December 9, 2010

Selective activation of the prostaglandin E2 receptor subtype EP2 or EP4 leads to inhibition of platelet aggregation

scientific article published on 20 July 2010

Single-cell RNA sequencing identifies a migratory keratinocyte subpopulation expressing THBS1 in epidermal wound healing

scientific article published on 21 March 2022

Stimulation of bone formation and prevention of bone loss by prostaglandin E EP4 receptor activation

scientific article

Stress responses: the contribution of prostaglandin E2 and its receptors ⬇️

scientific article published on November 30, 2010

Suppression of polyI:C-inducible gene expression by EP3 in murine conjunctival epithelium

scientific article published on 12 September 2013

Suppression of polyi:c-inducible gene expression by EP3 in murine conjunctival epithelium

scientific article published on 17 March 2014

Sustained expression of MCP-1 by low wall shear stress loading concomitant with turbulent flow on endothelial cells of intracranial aneurysm

scientific article published on 9 May 2016

T cell function is dispensable for intracranial aneurysm formation and progression

scientific article

T cell-intrinsic prostaglandin E-EP2/EP4 signaling is critical in pathogenic T17 cell-driven inflammation

scientific article published on 20 June 2018

TNF-alpha induces thromboxane receptor signaling-dependent microcirculatory dysfunction in mouse liver

scientific article

The Innate Immune Receptors TLR2/4 Mediate Repeated Social Defeat Stress-Induced Social Avoidance through Prefrontal Microglial Activation

scientific article published on 19 July 2018

The PGE2-EP4 receptor is necessary for stimulation of the renin-angiotensin-aldosterone system in response to low dietary salt intake in vivo ⬇️

scientific article published on September 19, 2012

The Rho-mDia1 pathway regulates cell polarity and focal adhesion turnover in migrating cells through mobilizing Apc and c-Src

scientific article

The intrinsic prostaglandin E2–EP4 system of the renal tubular epithelium limits the development of tubulointerstitial fibrosis in mice ⬇️

scientific article published on April 18, 2012

The novel prostaglandin I2 mimetic ONO-1301 escapes desensitization in an antiplatelet effect due to its inhibitory action on thromboxane A2 synthesis in mice

scientific article published on 04 March 2015

The prostaglandin receptor EP4 suppresses colitis, mucosal damage and CD4 cell activation in the gut

scientific article

Thromboxane A 2 Regulates Vascular Tone via Its Inhibitory Effect on the Expression of Inducible Nitric Oxide Synthase ⬇️

scientific article published on October 13, 2003

Thromboxane A2 and prostaglandin F2alpha mediate inflammatory tachycardia

scientific journal article

Thromboxane A2 facilitates IL-17A production from Vγ4+ γδ T cells and promotes psoriatic dermatitis in mice.

scientific article published on 17 April 2018

Thromboxane A2 modulates interaction of dendritic cells and T cells and regulates acquired immunity

scientific article published in June 2003

Thromboxane A2 receptor signaling in endothelial cells attenuates monocrotaline-induced liver injury

scientific article published on 27 August 2019

Thromboxane A2 receptor signaling promotes liver tissue repair after toxic injury through the enhancement of macrophage recruitment ⬇️

scientific article published on December 21, 2011

Thromboxane receptor activation enhances striatal dopamine release, leading to suppression of GABAergic transmission and enhanced sugar intake

scientific article published on 12 July 2011

Timely interaction between prostaglandin and chemokine signaling is a prerequisite for successful fertilization

scholarly article

Two Diverse Hemodynamic Forces, a Mechanical Stretch and a High Wall Shear Stress, Determine Intracranial Aneurysm Formation

scientific article published on 08 February 2019

Ulk2 controls cortical excitatory-inhibitory balance via autophagic regulation of p62 and GABAA receptor trafficking in pyramidal neurons

scientific article published on 01 September 2018

Vasa vasorum formation is associated with rupture of intracranial aneurysms

scientific article published on 16 August 2019

mDia and ROCK Mediate Actin-Dependent Presynaptic Remodeling Regulating Synaptic Efficacy and Anxiety.

scientific article published in November 2016

mDia1 targets v-Src to the cell periphery and facilitates cell transformation, tumorigenesis, and invasion

scientific article

mDia1/3 generate cortical F-actin meshwork in Sertoli cells that is continuous with contractile F-actin bundles and indispensable for spermatogenesis and male fertility

scientific article published on 26 September 2018

mDia1/3-dependent actin polymerization spatiotemporally controls LAT phosphorylation by Zap70 at the immune synapse

scientific article published on 01 January 2020

List of works by Shuh Narumiya

A role for mDia, a Rho-regulated actin nucleator, in tangential migration of interneuron precursors

A sphingosine-1-phosphate receptor type 1 agonist, ASP4058, suppresses intracranial aneurysm through promoting endothelial integrity and blocking macrophage transmigration

Actin polymerization-driven molecular movement of mDia1 in living cells

Adhesion of platelets through thromboxane A₂ receptor signaling facilitates liver repair during acute chemical-induced hepatotoxicity

An essential role of Cdc42-like GTPases in mitosis of HeLa cells

Anti-inflammatory role of PGD 2 in acute lung inflammation and therapeutic application of its signal enhancement ⬇️

Aquaporin-3 potentiates allergic airway inflammation in ovalbumin-induced murine asthma

Arachidonic acid and prostacyclin signaling promote adipose tissue development: a human health concern?

Augmented cardiac hypertrophy in response to pressure overload in mice lacking the prostaglandin I2 receptor

Bone marrow-derived EP3-expressing stromal cells enhance tumor-associated angiogenesis and tumor growth

CCAAT/enhancer-binding protein delta/miR135a/thrombospondin 1 axis mediates PGE2-induced angiogenesis in Alzheimer's disease

Cdc42 and Rac family GTPases regulate mode and speed but not direction of primary fibroblast migration during platelet-derived growth factor-dependent chemotaxis

Central PGE2exhibits anxiolytic-like activity via EP1and EP4receptors in a manner dependent on serotonin 5-HT1A, dopamine D1and GABAAreceptors ⬇️

Characteristics of thermoregulatory and febrile responses in mice deficient in prostaglandin EP1 and EP3 receptors

Cigarette Smoke Extract Inhibits Platelet Aggregation by Suppressing Cyclooxygenase Activity

Constitutive Activation of Integrin α9 Augments Self-Directed Hyperplastic and Proinflammatory Properties of Fibroblast-like Synoviocytes of Rheumatoid Arthritis

Conversion of antigen-specific effector/memory T cells into Foxp3-expressing Treg cells by inhibition of CDK8/19

Critical role of TNF-alpha-TNFR1 signaling in intracranial aneurysm formation

Crystal structure of the endogenous agonist-bound prostanoid receptor EP3

Deficiency of mDia, an actin nucleator, disrupts integrity of neuroepithelium and causes periventricular dysplasia.

Definition of Prostaglandin E2-EP2 Signals in the Colon Tumor Microenvironment That Amplify Inflammation and Tumor Growth

Disruption of Actin Dynamics Regulated by Rho Effector mDia1 Attenuates Pressure Overload-Induced Cardiac Hypertrophic Responses and Exacerbates Dysfunction

Dual functions of prostaglandin D2 in murine contact hypersensitivity via DP and CRTH2.

Dual roles of PGE2-EP4 signaling in mouse experimental autoimmune encephalomyelitis

EP2and EP4receptors on muscularis resident macrophages mediate LPS-induced intestinal dysmotility via iNOS upregulation through cAMP/ERK signals ⬇️

EP3 signaling in dendritic cells promotes liver repair by inducing IL-13-mediated macrophage differentiation in mice

Effects of the prostanoids on the proliferation or hypertrophy of cultured murine aortic smooth muscle cells

Emerging roles of prostanoids in T cell‐mediated immunity ⬇️

EphA4-dependent axon retraction and midline localization of Ephrin-B3 are disrupted in the spinal cord of mice lacking mDia1 and mDia3 in combination.

Epistatic interaction between Toll-like receptor 3 (TLR3) and prostaglandin E receptor 3 (PTGER3) genes

Erratum: Prostaglandin E2 promotes Th1 differentiation via synergistic amplification of IL-12 signalling by cAMP and PI3-kinase

Exacerbation of intracranial aneurysm and aortic dissection in hypertensive rat treated with the prostaglandin F-receptor antagonist AS604872.

Expression of prostaglandin F receptor in scleral and subconjunctival tissue ⬇️

Expression of the prostaglandin F receptor (FP) gene along the mouse genitourinary tract

Expression profiling of cumulus cells reveals functional changes during ovulation and central roles of prostaglandin EP2 receptor in cAMP signaling

F- and G-actin homeostasis regulates mechanosensitive actin nucleation by formins ⬇️

Fever, inflammation, pain and beyond: prostanoid receptor research during these 25 years ⬇️

Functional evidence for interaction between prostaglandin EP3 and kappa-opioid receptor pathways in tactile pain induced by human immunodeficiency virus type-1 (HIV-1) glycoprotein gp120.

G-CSF-induced sympathetic tone provokes fever and primes antimobilizing functions of neutrophils via PGE2.

G-actin regulates rapid induction of actin nucleation by mDia1 to restore cellular actin polymers

Genetic and pharmacological inhibition of Rho-associated kinase II enhances adipogenesis.

Hepatic stellate cells relay inflammation signaling from sinusoids to parenchyma in mouse models of immune-mediated hepatitis

Host prostaglandin E(2)-EP3 signaling regulates tumor-associated angiogenesis and tumor growth

Host prostaglandin EP3 receptor signaling relevant to tumor-associated lymphangiogenesis

Identification of EP4 as a potential target for the treatment of castration-resistant prostate cancer using a novel xenograft model

Impaired adrenocorticotropic hormone response to bacterial endotoxin in mice deficient in prostaglandin E receptor EP1 and EP3 subtypes

Impaired vascular remodeling in the yolk sac of embryos deficient in ROCK-I and ROCK-II ⬇️

Improvement of cognitive function in Alzheimer's disease model mice by genetic and pharmacological inhibition of the EP(4) receptor

Inactivation of Rho GTPases with Clostridium difficile toxin B impairs centrosomal activation of Aurora-A in G2/M transition of HeLa cells

Inhibition of microsomal prostaglandin E synthase-1 facilitates liver repair after hepatic injury in mice

Involvement of cyclooxygenase-2 and EP3 prostaglandin receptor in acute herpetic but not postherpetic pain in mice

Involvement of prostaglandin E receptor subtype EP(4) in colon carcinogenesis.

Involvement of prostaglandin E2 in production of amyloid-beta peptides both in vitro and in vivo

LPA Induces Keratinocyte Differentiation and Promotes Skin Barrier Function through the LPAR1/LPAR5-RHO-ROCK-SRF Axis

Ligand binding to human prostaglandin E receptor EP4 at the lipid-bilayer interface

Lipocalin-type prostaglandin D synthase regulates light-induced phase advance of the central circadian rhythm in mice

Loss of a Rho-regulated actin nucleator, mDia2, impairs cytokinesis during mouse fetal erythropoiesis

Macrophage Imaging of Cerebral Aneurysms with Ferumoxytol: an Exploratory Study in an Animal Model and in Patients.

Migration without a clutch

Molecular identification and characterization of a family of kinases with homology to Ca2+/calmodulin-dependent protein kinases I/IV

Multiple spatiotemporal modes of actin reorganization by NMDA receptors and voltage-gated Ca2+ channels

Opposing immunomodulatory roles of prostaglandin D2 during the progression of skin inflammation

Orally administered rubiscolin-6, a δ opioid peptide derived from Rubisco, stimulates food intake via leptomeningeal lipocallin-type prostaglandin D synthase in mice

PS144. Dopamine D1 receptor in the medial prefrontal cortex mediates behavioral resilience under stress in mice.

PS205. Innate immune molecules activate microglia in mPFC to induce neuronal and emotional changes in mice.

Pathophysiological roles of the prostanoids in the cardiovascular system: studies using mice deficient in prostanoid receptors

Prostacyclin-IP signaling and prostaglandin E2-EP2/EP4 signaling both mediate joint inflammation in mouse collagen-induced arthritis

Prostaglandin D 2 -DP Signaling Promotes Endothelial Barrier Function via the cAMP/PKA/Tiam1/Rac1 Pathway ⬇️

Prostaglandin D2 protects neonatal mouse brain from hypoxic ischemic injury.

Prostaglandin D2-mediated microglia/astrocyte interaction enhances astrogliosis and demyelination in twitcher.

Prostaglandin E receptor EP1 controls impulsive behavior under stress.

Prostaglandin E receptor EP1 enhances GABA-mediated inhibition of dopaminergic neurons in the substantia nigra pars compacta and regulates dopamine level in the dorsal striatum

Prostaglandin E receptor EP1 forms a complex with dopamine D1 receptor and directs D1-induced cAMP production to adenylyl cyclase 7 through mobilizing G(βγ) subunits in human embryonic kidney 293T cells.

Prostaglandin E receptor EP3 deficiency modifies tumor outcome in mouse two-stage skin carcinogenesis

Prostaglandin E receptor EP4 stimulates lymphangiogenesis to promote mucosal healing during DSS-induced colitis

Prostaglandin E receptor subtype EP(1) deficiency inhibits colon cancer development

Prostaglandin E receptor subtype EP3 in conjunctival epithelium regulates late-phase reaction of experimental allergic conjunctivitis

Prostaglandin E receptors

Prostaglandin E(2) regulates murine hematopoietic stem/progenitor cells directly via EP4 receptor and indirectly through mesenchymal progenitor cells.