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List of works by Derek B Sant'Angelo

A novel TCR transgenic model reveals that negative selection involves an immediate, Bim-dependent pathway and a delayed, Bim-independent pathway

scientific article

A pool of central memory-like CD4 T cells contains effector memory precursors

scientific article published in March 2003

A transgenic TCR directs the development of IL-4+ and PLZF+ innate CD4 T cells

scientific article published on 17 June 2013

Altered development of NKT cells, γδ T cells, CD8 T cells and NK cells in a PLZF deficient patient

scientific article

An alternate pathway for CD4 T cell development: thymocyte-expressed MHC class II selects a distinct T cell population

scientific article published on 01 October 2005

Are fat NKT cells born that way?

scientific article published on 03 July 2017

Coevolution of TCR-MHC interactions: conserved MHC tertiary structure is not sufficient for interactions with the TCR.

scientific article

Coexpression of YY1 Is Required to Elaborate the Effector Functions Controlled by PLZF in NKT Cells

scientific article published on 21 June 2019

Corrigendum: TCRα-TCRβ pairing controls recognition of CD1d and directs the development of adipose NKT cells.

scientific article published in July 2017

Development of CD1d-restricted NKT cells in the mouse thymus

scientific article published in December 2004

Development of PLZF-expressing innate T cells ⬇️

scientific article published on January 21, 2011

Development of promyelocytic leukemia zinc finger-expressing innate CD4 T cells requires stronger T-cell receptor signals than conventional CD4 T cells.

scientific article

Development of promyelocytic zinc finger and ThPOK-expressing innate gamma delta T cells is controlled by strength of TCR signaling and Id3.

scientific article published on 28 December 2009

Dipping into the cytosol to broaden the MHC class II peptide repertoire

scientific article published on 01 May 2005

Direct identification of rat iNKT cells reveals remarkable similarities to human iNKT cells and a profound deficiency in LEW rats

scientific article published on 26 December 2012

Distinct PLZF+CD8αα+ Unconventional T Cells Enriched in Liver Use a Cytotoxic Mechanism to Limit Autoimmunity

scientific article published on 25 September 2019

Ectopic T Cell Receptor-α Locus Control Region Activity in B Cells Is Suppressed by Direct Linkage to Two Flanking Genes at Once ⬇️

scientific article published on November 22, 2010

Ectopic expression of HLA-DO in mouse dendritic cells diminishes MHC class II antigen presentation

scientific article published on 01 August 2004

Fulminant experimental autoimmune encephalo-myelitis induced by retrovirally mediated TCR gene transfer

scientific article published in June 2005

Histone deacetylase 3 is required for iNKT cell development

scientific article

Innate immune activation and CD4+ T cell priming during respiratory fungal infection

scientific article published on 05 October 2006

Intratumoral injection of the seasonal flu shot converts immunologically cold tumors to hot and serves as an immunotherapy for cancer

scientific article published on 30 December 2019

Label retention identifies a multipotent mesenchymal stem cell-like population in the postnatal thymus

scientific article

NKAP Regulates Invariant NKT Cell Proliferation and Differentiation into ROR-γt-Expressing NKT17 Cells.

scientific article published on 9 May 2016

Negative selection of thymocytes expressing the D10 TCR

scientific article

PLZF induces the spontaneous acquisition of memory/effector functions in T cells independently of NKT cell-related signals

scientific article

Recognition of a specific self-peptide: self-MHC class II complex is critical for positive selection of thymocytes expressing the D10 TCR.

scientific article published on January 2003

Recognition of core and flanking amino acids of MHC class II-bound peptides by the T cell receptor

scientific article

Regulatory iNKT cells lack expression of the transcription factor PLZF and control the homeostasis of T(reg) cells and macrophages in adipose tissue

scientific article published in December 2014

Requirements for Eomesodermin and Promyelocytic Leukemia Zinc Finger in the Development of Innate-Like CD8+ T Cells ⬇️

scientific article published on March 7, 2011

Selective depletion of eosinophils or neutrophils in mice impacts the efficiency of apoptotic cell clearance in the thymus

scientific article

TCR Affinity for Self-Ligands Influences the Development and Function of Encephalitogenic T Cells ⬇️

scientific article published on March 17, 2011

TCRα-TCRβ pairing controls recognition of CD1d and directs the development of adipose NKT cells.

scientific article published on 21 November 2016

Targeted regulation of self-peptide presentation prevents type I diabetes in mice without disrupting general immunocompetence

scientific article

The BTB-ZF Family of Transcription Factors: Key Regulators of Lineage Commitment and Effector Function Development in the Immune System ⬇️

scientific article published on September 15, 2011

The BTB-zinc finger transcriptional regulator PLZF controls the development of invariant natural killer T cell effector functions

scientific article

The Paf oncogene is essential for hematopoietic stem cell function and development ⬇️

scientific article published on August 15, 2011

The Transcription Factor PLZF Is Necessary for the Development and Function of Mouse Basophils

scientific article published on 31 July 2019

The transcriptional repressor NKAP is required for the development of iNKT cells

scientific article published on January 2013

Transcription factor Bcl11b sustains iNKT1 and iNKT2 cell programs, restricts iNKT17 cell program, and governs iNKT cell survival

scientific article published on 21 June 2016

Transcriptional control of invariant NKT cell development ⬇️

scientific article published on November 1, 2010

Tumor immunotherapy across MHC barriers using allogeneic T-cell precursors

scientific article

YY1lo NKT cells are dedicated IL-10 producers

scientific article published on 03 March 2020

Yin Yang 1 Promotes Thymocyte Survival by Downregulating p53.

scientific article published on 3 February 2016

Zbtb16 (PLZF) is stably suppressed and not inducible in non-innate T cells via T cell receptor-mediated signaling

scientific article published on 16 July 2015

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