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List of works by David E. J. Jones

A Novel Method for Continuous, Noninvasive, Cuff-Less Measurement of Blood Pressure: Evaluation in Patients With Nonalcoholic Fatty Liver Disease

scientific article published on 12 September 2016

A Placebo-Controlled Trial of Obeticholic Acid in Primary Biliary Cholangitis

scientific article published in August 2016

A Randomized Trial of Obeticholic Acid Monotherapy in Patients with Primary Biliary Cholangitis.

scientific article published on 10 October 2017

A Randomized, Controlled, Phase 2 Study of Maralixibat in the Treatment of Itching Associated With Primary Biliary Cholangitis

scientific article published on 01 February 2019

A Transcriptional Signature of Fatigue Derived from Patients with Primary Sjögren's Syndrome

scientific article published on 22 December 2015

A follow-up study of modafinil for the treatment of daytime somnolence and fatigue in primary biliary cirrhosis

scientific article published in November 2010

A key role for autoreactive B cells in the breakdown of T-cell tolerance to pyruvate dehydrogenase complex in the mouse

scientific article published in May 2005

A potential retroviral aetiology for mouse PBC: More answers or more questions? ⬇️

scientific article published on 09 March 2011

A predictive model for fatigue and its etiologic associations in primary biliary cirrhosis

scientific article published in February 2008

A randomized trial of antioxidant therapy alone or with corticosteroids in acute alcoholic hepatitis

scientific article published on 4 May 2007

Abnormalities of AMPK activation and glucose uptake in cultured skeletal muscle cells from individuals with chronic fatigue syndrome

scientific article (publication date: 2015)

Access to Care in Rare Liver Diseases: New Challenges and New Opportunities

scientific article published on 4 November 2017

Acetate, the key modulator of inflammatory responses in acute alcoholic hepatitis.

scientific article published on June 2010

Addison's other disease: primary biliary cirrhosis as a model autoimmune disease.

scientific article

Amino acid residues in five separate HLA genes can explain most of the known associations between the MHC and primary biliary cholangitis

article

An integrated care pathway improves quality of life in Primary Biliary Cirrhosis

scientific article published on 3 April 2008

An international genome-wide meta-analysis of primary biliary cholangitis: Novel risk loci and candidate drugs

scientific article

Apical Sodium-Dependent Transporter Inhibitors in Primary Biliary Cholangitis and Primary Sclerosing Cholangitis.

scientific article published on March 2017

Are Clinicians Ready for Safe Use of Stratified Therapy in Primary Biliary Cholangitis (PBC)? A Study of Educational Awareness

scientific article published on 08 May 2018

Assessing quality of life in primary biliary cirrhosis

scientific article published on 01 February 2004

Authors' reply

Autonomic dysfunction in primary biliary cirrhosis correlates with fatigue severity

article

Autotaxin, bile acid profile and effect of ileal bile acid transporter inhibition in primary biliary cholangitis patients with pruritus

scientific article published on 25 February 2019

BAT117213: Ileal bile acid transporter (IBAT) inhibition as a treatment for pruritus in primary biliary cirrhosis: study protocol for a randomised controlled trial

scientific article

Bacterial motif DNA as an adjuvant for the breakdown of immune self-tolerance to pyruvate dehydrogenase complex

scientific article published in September 2002

Bile acid receptor agonists in primary biliary cholangitis: Regulation of the cholangiocyte secretome and downstream T cell differentiation

scientific article published on 22 April 2019

Biliary epithelial-mesenchymal transition in posttransplantation recurrence of primary biliary cirrhosis

scientific article published on 01 April 2007

Cardiac torsion-strain relationships in fatigued primary biliary cirrhosis patients show accelerated aging: a pilot cross-sectional study ⬇️

scientific article published on March 29, 2012

Central nervous system dysfunction in primary biliary cirrhosis and its relationship to symptoms

scientific article published on 11 August 2010

Changes in natural killer cells and exhausted memory regulatory T Cells with corticosteroid therapy in acute autoimmune hepatitis

scientific article published on 26 February 2018

Changing Nomenclature for PBC: From 'Cirrhosis' to 'Cholangitis'

scientific article published on 18 September 2015

Changing Nomenclature for PBC: From 'Cirrhosis' to 'Cholangitis'.

scientific article

Changing nomenclature for PBC: From 'cirrhosis' to 'cholangitis'

scientific article published on 26 September 2015

Changing nomenclature for PBC: From 'cirrhosis' to 'cholangitis'

scientific article published on 01 October 2015

Changing nomenclature for PBC: From 'cirrhosis' to 'cholangitis'.

scientific article

Changing nomenclature for PBC: from 'cirrhosis' to 'cholangitis'.

scientific article published on 15 September 2015

Changing nomenclature for PBC: from 'cirrhosis' to 'cholangitis'.

scientific article

Characterisation of the associations and impact of symptoms in primary biliary cirrhosis using a disease specific quality of life measure

scientific article published on 23 January 2006

Chronic liver disease in an ageing population.

scientific article

Clinical application of the GLOBE and United Kingdom-primary biliary cholangitis risk scores in a trial cohort of patients with primary biliary cholangitis.

scientific article

Cognitive impairment in non-cirrhotic chronic liver disease is unrelated to liver disease severity but associated with ineffective baroreflex function

scientific article published on 04 November 2011

Cognitive impairment in primary biliary cirrhosis: symptom impact and potential etiology

scientific article published in August 2008

Comment on biochemical response to ursodeoxycholic acid and long-term prognosis in primary biliary cirrhosis

scientific article published in January 2009

Corrigendum to "The independent effects of fatigue and UDCA therapy on mortality in primary biliary cirrhosis: Results of a 9 year cohort follow-up" J. Hepatol. 2010 Nov; 53(5):911-917

scientific article published on 25 May 2011

Covalent modification as a mechanism for the breakdown of immune tolerance to pyruvate dehydrogenase complex in the mouse.

scientific article

Cytotoxic T-lymphocyte-associated antigen-4 single nucleotide polymorphisms and haplotypes in primary biliary cirrhosis

article

Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis

scientific article

Development and adaptation of patient-reported outcome measures for patients who experience itch associated with primary biliary cholangitis

article

Development of an Evidence-Based Patient Information Medium: Empowering Newly Diagnosed Patients With Primary Biliary Cirrhosis

scientific article published on 01 March 2011

Diagnosis and management of patients with primary biliary cirrhosis

scientific article published on 01 March 2014

Drug treatment of pruritus in liver diseases.

scientific article published on August 2015

Early Molecular Stratification of High-risk Primary Biliary Cholangitis

scientific article

Editorial: rapid assessment of health-related quality of life in primary biliary cholangitis-no excuse not to ask. Authors' reply

scientific article published on 01 January 2020

Effect of ileal bile acid transporter inhibitor GSK2330672 on pruritus in primary biliary cholangitis: a double-blind, randomised, placebo-controlled, crossover, phase 2a study.

scientific article published on 7 February 2017

Effects of Primary Biliary Cholangitis on Quality of Life and Health Care Costs in the United Kingdom

scientific article published on 17 June 2020

Emerging drugs for the treatment of primary biliary cholangitis

scientific article published on 07 April 2020

Epithelial to mesenchymal transition in primary sclerosing cholangitis

scientific article published on 01 September 2008

Epithelial-mesenchymal transition contributes to portal tract fibrogenesis during human chronic liver disease

scientific article published on 03 December 2007

Exercise therapy in primary biliary cirrhosis: the importance of moving while sitting on a surgical waiting list-a case study

scientific article published on 12 April 2016

Falls and fall-related injury are common in older people with chronic liver disease.

scientific article published on 11 May 2012

Fat is an immuno-regulatory issue

scientific article published on 01 October 2005

Fatigue and autonomic dysfunction in non-alcoholic fatty liver disease

scientific article published in December 2009

Fatigue in Primary Biliary Cirrhosis: Prevalence, Pathogenesis and Management

scientific article

Fatigue in cholestatic liver disease: is it all in the mind?

scientific article published on 26 March 2007

Fatigue in chronic liver disease: New insights and therapeutic approaches

scientific article published on 10 August 2018

Fatigue in primary biliary cirrhosis

scientific article published on 22 October 2012

Fatigue in primary biliary cirrhosis is associated with excessive daytime somnolence

scientific article published in July 2006

Fatigue in primary sclerosing cholangitis is associated with sympathetic over-activity and increased cardiac output

scientific article published on 4 December 2014

Folic acid handling by the human gut: implications for food fortification and supplementation.

scientific article

Functional capacity is significantly impaired in primary biliary cirrhosis and is related to orthostatic symptoms

scientific article published on 01 July 2011

Functional impairment in alcoholic liver disease and non-alcoholic fatty liver disease is significant and persists over 3 years of follow-up

scientific article

Genetic and epigenetic factors in autoimmune reactions toward cytochrome P4502E1 in alcoholic liver disease.

scientific article published in February 2003

Genetic factors in the pathogenesis of primary biliary cirrhosis ⬇️

scientific article published on November 1, 2003

Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis

scientific article

Globus pallidus magnetization transfer ratio, T(1) and T(2) in primary biliary cirrhosis: relationship with disease stage and age.

scientific article published in April 2009

HLA class II alleles, genotypes, haplotypes, and amino acids in primary biliary cirrhosis: a large-scale study

scientific article published on 01 September 2006

Health related quality of life in people with advanced chronic liver disease.

scientific article published on 07 July 2014

Identification of a xenobiotic as a potential environmental trigger in primary biliary cholangitis

scientific article published on 11 July 2018

Impact of primary biliary cirrhosis on perceived quality of life: the UK-PBC national study

scientific article

Impaired cardiovascular function in primary biliary cirrhosis

scientific article

Impaired cardiovascular response to standing in chronic fatigue syndrome

scientific article published on 23 May 2010

Impaired cerebral autoregulation in primary biliary cirrhosis: implications for the pathogenesis of cognitive decline.

scientific article

Inequity of care provision and outcome disparity in autoimmune hepatitis in the United Kingdom

scientific article published on 18 September 2018

Investigation of a mechanism for accelerated breakdown of immune tolerance to the primary biliary cirrhosis-associated autoantigen, pyruvate dehydrogenase complex

scientific article published in February 2002

Itch and liver: management in primary care.

scientific article published on June 2015

Letter: histology is relevant for risk stratification in primary biliary cholangitis

scientific article published on 01 January 2020

Liver disease in the UK.

scientific article

Long-Term Fenofibrate Treatment in Primary Biliary Cholangitis Improves Biochemistry but Not the UK-PBC Risk Score

scientific article published on 19 July 2016

Loss of capacity to recover from acidosis in repeat exercise is strongly associated with fatigue in primary biliary cirrhosis

scientific article published on 31 March 2010

Loss of capacity to recover from acidosis on repeat exercise in chronic fatigue syndrome: a case-control study

scientific article published on 12 July 2011

Lower ambulatory blood pressure in chronic fatigue syndrome.

scientific article

Making sense of fatigue

scientific article published in August 2010

Managing systemic symptoms in chronic liver disease ⬇️

scientific article published on January 1, 2012

Metastatic breast carcinoma presenting as acute liver failure and portal hypertension

scientific article published on 01 March 2002

Microvascular optical assessment confirms the presence of peripheral autonomic dysfunction in primary biliary cirrhosis

scientific article published on 7 July 2009

NI-0801, an anti-chemokine (C-X-C motif) ligand 10 antibody, in patients with primary biliary cholangitis and an incomplete response to ursodeoxycholic acid.

scientific article published on 23 March 2018

Novel bile acid therapeutics for the treatment of chronic liver diseases

scientific article

Novel strategies and therapeutic options for the management of primary biliary cholangitis

scientific article published on 7 September 2017

Novel therapeutic targets in primary biliary cirrhosis

scientific article

Obeticholic acid for the treatment of primary biliary cirrhosis

article

Oral tolerisation to pyruvate dehydrogenase complex as a potential therapy for primary biliary cirrhosis.

scientific article published in December 2002

Orthostatic intolerance is common in chronic disease--a clinical cohort study

scientific article published on 26 April 2014

Oxidative stress as a trigger for cellular immune responses in patients with alcoholic liver disease

scientific article published in January 2004

PBC-10: a short quality of life measure for clinical screening in primary biliary cholangitis

scientific article published on 30 October 2019

PBC: Better Solutions to Beat Feeling Beat

scientific article published on 01 August 2019

PDC-E3BP is not a dominant T-cell autoantigen in primary biliary cirrhosis

scientific article (publication date: May 2006)

Pain as a complication of use of opiate antagonists for symptom control in cholestasis

scientific article published on 01 August 2003

Pathogenesis of cholestatic itch: Old questions, new answers, and future opportunities ⬇️

scientific article published on October 1, 2012

Pathogenesis of primary biliary cirrhosis

scientific article

Pathogenesis of primary biliary cirrhosis

scientific article published on 01 October 2003

Pathogenesis of primary biliary cirrhosis

scientific article published on 01 May 2008

Pathogenesis of primary biliary cirrhosis and its fatigue

scientific article published on 14 July 2014

Pilot study of peripheral muscle function in primary biliary cirrhosis: potential implications for fatigue pathogenesis

scientific article published on 8 August 2008

Population prevalence and symptom associations of autonomic dysfunction in primary biliary cirrhosis.

scientific article published in June 2007

Position statement on access to care in rare liver diseases: advancements of the European reference network (ERN) RARE-LIVER

scientific article published on 08 July 2019

Potential strategies to improve uptake of exercise interventions in non-alcoholic fatty liver disease

scientific article published on 23 October 2009

Pretreatment prediction of response to ursodeoxycholic acid in primary biliary cholangitis: development and validation of the UDCA Response Score

scientific article published on 13 July 2018

Primary biliary cirrhosis

scientific article published on 01 June 2004

Primary biliary cirrhosis: report of a focus study group

scientific article published in October 2004

Primary sclerosing cholangitis

scientific article published on 13 February 2018

Progenitor-derived hepatocyte-like (B-13/H) cells metabolise 1'-hydroxyestragole to a genotoxic species via a SULT2B1-dependent mechanism.

scientific article published on 28 December 2015

Pruritus Is Common and Undertreated in Patients With Primary Biliary Cholangitis in the United Kingdom

scientific article published on 14 December 2018

RITPBC: B-cell depleting therapy (rituximab) as a treatment for fatigue in primary biliary cirrhosis: study protocol for a randomised controlled trial

scientific article

Reduced heart rate variability and baroreflex sensitivity in primary biliary cirrhosis.

scientific article published in March 2006

Reduced thoracic fluid content in early-stage primary biliary cirrhosis that associates with impaired cardiac inotropy.

scientific article published on 18 July 2013

Reduction in functional ability is significant postliver transplantation compared with matched liver disease and community dwelling controls

scientific article published on 08 March 2011

Reflections on therapeutic trials in primary biliary cirrhosis: a quality of life oriented counter-view.

scientific article published in March 2006

Reply to: "Fatigue and liver transplantation in patients with primary biliary cirrhosis"

scientific article published on 12 February 2014

Restless leg syndrome is a treatable cause of sleep disturbance and fatigue in primary biliary cirrhosis.

scientific article published in February 2013

Rituximab Is Ineffective for Treatment of Fatigue in Primary Biliary Cholangitis: A Phase 2 Randomized Controlled Trial

scientific article published on 22 September 2018

Rituximab for the treatment of fatigue in primary biliary cholangitis (formerly primary biliary cirrhosis): a randomised controlled trial

scientific article published on 8 May 2018

Schrödinger's pipeline and the outsourcing of pharmaceutical innovation

scientific article published on 10 December 2019

Seladelpar (MBX-8025), a selective PPAR-δ agonist, in patients with primary biliary cholangitis with an inadequate response to ursodeoxycholic acid: a double-blind, randomised, placebo-controlled, phase 2, proof-of-concept study

scientific article

Serum anti-mitochondrial antibodies and fatigue in primary biliary cirrhosis

scientific article published on 01 September 2009

Sex and Age Are Determinants of the Clinical Phenotype of Primary Biliary Cirrhosis and Response to Ursodeoxycholic Acid ⬇️

scientific article published on December 12, 2012

Stratified medicine and primary biliary cholangitis.

scientific article

T cell-mediated biliary epithelial-to-mesenchymal transition in liver allograft rejection.

scientific article

TGF-β2 silencing to target biliary-derived liver diseases

scientific article published on 28 January 2020

The British Society of Gastroenterology/UK-PBC primary biliary cholangitis treatment and management guidelines

scientific article published on 28 March 2018

The Impact of Autoimmune Hepatitis and its Treatment on Health Utility.

scientific article published on 17 April 2018

The UK-PBC risk scores: Derivation and validation of a scoring system for long-term prediction of end-stage liver disease in primary biliary cholangitis.

scientific article published on 29 July 2015

The challenges of primary biliary cholangitis: What is new and what needs to be done

scientific article published on 20 September 2019

The complexity of fatigue ⬇️

scientific article published on October 1, 2010

The effect of liver transplantation on fatigue in patients with primary biliary cirrhosis: a prospective study

scientific article published on 27 April 2013

The genetics of primary biliary cirrhosis: the revolution moves on

scientific article published on 01 January 2011

The impact of liver transplantation on the phenotype of primary biliary cirrhosis patients in the UK-PBC cohort.

scientific article

The independent effects of fatigue and UDCA therapy on mortality in primary biliary cirrhosis: Results of a 9year follow-up ⬇️

scientific article published on August 1, 2010

The new epidemiology of primary biliary cirrhosis

scientific article

The role of psychological factors in the fatigue of primary biliary cirrhosis

scientific article published in June 2007

The specificity of liver inflammation in mouse models of primary biliary cirrhosis

scientific article

The toxicity of the methylimidazolium ionic liquids, with a focus on M8OI and hepatic effects

scientific article published on 27 December 2019

The true impact of fatigue in primary biliary cirrhosis: a population study

scientific article published on May 2002

Theophylline improves steroid sensitivity in acute alcoholic hepatitis

scientific article published in July 2010

Toll-like receptor (TLR) response tolerance: a key physiological "damage limitation" effect and an important potential opportunity for therapy.

scientific article published on January 2006

Toll-like receptor interactions: tolerance of MyD88-dependent cytokines but enhancement of MyD88-independent interferon-beta production

scientific article published on 11 October 2006

Tumour necrosis factor-α promoter polymorphisms in primary biliary cirrhosis

UDCA prophylaxis for post-transplant PBC recurrence prevention: Time to change practice

scientific article published on 20 June 2020

Understanding Fatigue in Primary Biliary Cholangitis

scientific article published on 26 August 2020

Understanding and Treating Fatigue in Primary Biliary Cirrhosis and Primary Sclerosing Cholangitis

scientific article published on February 2016

Unmet clinical need in autoimmune liver diseases

scientific article

Unmet needs and new models for future trials in autoimmune hepatitis

scientific article published on 6 April 2018

Ustekinumab for patients with primary biliary cholangitis who have an inadequate response to ursodeoxycholic acid: A proof-of-concept study

scientific article

Variability of perceived fatigue in primary biliary cirrhosis: implications for symptom assessment

scientific article published on 11 September 2009

What Comes after Ursodeoxycholic Acid in Primary Biliary Cholangitis?

scientific article published on 3 May 2017

What impact has the NIHR Academic Clinical Fellowship (ACF) scheme had on clinical academic careers in England over the last 10 years? A retrospective study

scientific article published on 12 June 2017

Xenobiotic incorporation into pyruvate dehydrogenase complex can occur via the exogenous lipoylation pathway

scientific article

αEβ7 Integrin Identifies Subsets of Pro-Inflammatory Colonic CD4+ T Lymphocytes in Ulcerative Colitis

scientific article published on May 2017

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