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List of works by Erik T Dustrude

(Biphenyl-4-yl)methylammonium chlorides: potent anticonvulsants that modulate Na+ currents

scientific article published on 03 July 2013

A single structurally conserved SUMOylation site in CRMP2 controls NaV1.7 function.

scientific article

CRMP2 protein SUMOylation modulates NaV1.7 channel trafficking

scientific article published on 08 July 2013

Carbamazepine potentiates the effectiveness of morphine in a rodent model of neuropathic pain

scientific article

Chimeric agents derived from the functionalized amino acid, lacosamide, and the α-aminoamide, safinamide: evaluation of their inhibitory actions on voltage-gated sodium channels, and antiseizure and antinociception activities and comparison with lac

scientific article

Chimeric derivatives of functionalized amino acids and α-aminoamides: compounds with anticonvulsant activity in seizure models and inhibitory actions on central, peripheral, and cardiac isoforms of voltage-gated sodium channels.

scientific article published on 11 April 2015

Discovery of lacosamide affinity bait agents that exhibit potent voltage-gated sodium channel blocking properties

scientific article published on 16 January 2013

Dissecting the role of the CRMP2-neurofibromin complex on pain behaviors.

scientific article published on 31 July 2017

Hierarchical CRMP2 posttranslational modifications control NaV1.7 function

scientific article published on 08 December 2016

Homology-guided mutational analysis reveals the functional requirements for antinociceptive specificity of collapsin response mediator protein 2-derived peptides.

scientific article published on 5 February 2017

Identification of the benzyloxyphenyl pharmacophore: a structural unit that promotes sodium channel slow inactivation

scientific article

Inhibition of the Ubc9 E2 SUMO-conjugating enzyme-CRMP2 interaction decreases NaV1.7 currents and reverses experimental neuropathic pain

scientific article published on 01 October 2018

Inhibition of transmitter release and attenuation of anti-retroviral-associated and tibial nerve injury-related painful peripheral neuropathy by novel synthetic Ca2+ channel peptides

scientific article

Mining the Nav1.7 interactome: Opportunities for chronic pain therapeutics

scientific article published on 27 January 2019

Orexin Depolarizes Central Amygdala Neurons via Orexin Receptor 1, Phospholipase C and Sodium-Calcium Exchanger and Modulates Conditioned Fear

scientific article published on 18 December 2018

Sensitization of Ion Channels Contributes to Central and Peripheral Dysfunction in Neurofibromatosis Type 1.

scientific article published on 11 May 2016

Substituted N-(biphenyl-4'-yl)methyl (R)-2-acetamido-3-methoxypropionamides: potent anticonvulsants that affect frequency (use) dependence and slow inactivation of sodium channels

scientific article

The small molecule GAT1508 activates brain-specific GIRK1/2 channel heteromers and facilitates conditioned fear extinction in rodents

scientific article published on 17 January 2020

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