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List of works by Athar H Chishti

A Presenilin-like protease associated with Plasmodium falciparum micronemes is involved in erythrocyte invasion ⬇️

scientific article (publication date: March 2008)

A co-ligand complex anchors Plasmodium falciparum merozoites to the erythrocyte invasion receptor band 3.

scientific article published on 20 November 2003

A molecular switch that controls cell spreading and retraction

scientific article

Activation of transglutaminase in mu-calpain null erythrocytes

scientific article

Alternatively spliced exon 5 of the FERM domain of protein 4.1R encodes a novel binding site for erythrocyte p55 and is critical for membrane targeting in epithelial cells

scientific article published on 08 October 2008

Ankyrin peptide blocks falcipain-2-mediated malaria parasite release from red blood cells

scientific article published on 29 May 2003

Association of cottontail rabbit papillomavirus E6 oncoproteins with the hDlg/SAP97 tumor suppressor

scientific article

Atomic force microscopy demonstration of cytoskeleton instability in mouse erythrocytes with dematin‐headpiece and β‐adducin deficiency ⬇️

scientific article published on 02 June 2011

BDA-410: a novel synthetic calpain inhibitor active against blood stage malaria

scientific article published on 18 May 2007

Band 3 is a host receptor binding merozoite surface protein 1 during the Plasmodium falciparum invasion of erythrocytes ⬇️

scientific article published on April 11, 2003

Calpain is required for normal osteoclast function and is down-regulated by calcitonin

scientific article

Calpain-1 ablation partially rescues disease-associated hallmarks in models of Machado-Joseph disease

scientific article published on 21 January 2020

Calpain-1 contributes to IgE-mediated mast cell activation

scientific article

Calpain-1 knockout reveals broad effects on erythrocyte deformability and physiology

scientific article

Calpain-1 regulates platelet function in a humanized mouse model of sickle cell disease.

scientific article

Calpain-2 compensation promotes angiotensin II-induced ascending and abdominal aortic aneurysms in calpain-1 deficient mice

scientific article

Calpain-mediated regulation of platelet signaling pathways

scientific article published on May 2007

Centaurin-alpha1 interacts directly with kinesin motor protein KIF13B.

scientific article published in June 2005

Characterization of events preceding the release of malaria parasite from the host red blood cell

scientific article published on September 2005

Cloning and characterization of Plasmodium falciparum cysteine protease, falcipain-2B.

scientific article published on 3 April 2006

Combined deletion of mouse dematin-headpiece and beta-adducin exerts a novel effect on the spectrin-actin junctions leading to erythrocyte fragility and hemolytic anemia

scientific article published on 02 December 2006

Correction for Takano et al., "Vital Role of the Calpain-Calpastatin System for Placental-Integrity-Dependent Embryonic Survival".

scientific article published on 29 January 2018

Deletion of the Capn1 Gene Results in Alterations in Signaling Pathways Related to Alzheimer's Disease, Protein Quality Control and Synaptic Plasticity in Mouse Brain

scientific article published on 09 April 2020

Dematin and adducin provide a novel link between the spectrin cytoskeleton and human erythrocyte membrane by directly interacting with glucose transporter-1

scientific article

Dematin exhibits a natively unfolded core domain and an independently folded headpiece domain

scientific article

Dematin interacts with the Ras-guanine nucleotide exchange factor Ras-GRF2 and modulates mitogen-activated protein kinase pathways

scientific article

Differential expression of human Dlg in cervical intraepithelial neoplasias

scientific article published on May 2004

Direct interaction with a kinesin-related motor mediates transport of mammalian discs large tumor suppressor homologue in epithelial cells

scientific article

Distinct roles for μ-calpain and m-calpain in synaptic NMDAR-mediated neuroprotection and extrasynaptic NMDAR-mediated neurodegeneration.

scientific article

Dlg1, Sec8, and Mtmr2 regulate membrane homeostasis in Schwann cell myelination

scientific journal article

Double knockouts reveal that protein tyrosine phosphatase 1B is a physiological target of calpain-1 in platelets

scientific article

Dual Mechanism of Integrin αIIbβ3 Closure in Procoagulant Platelets ⬇️

scientific article published on March 21, 2013

Erythrocyte calpain is dispensable for malaria parasite invasion and growth

scientific article published in July 2002

Erythrocyte dematin is a candidate gene for Marie Unna hereditary hypotrichosis and related hairloss disorders

scientific article published on 01 May 2008

Erythrocyte scaffolding protein p55/MPP1 functions as an essential regulator of neutrophil polarity

scientific article

Expression of Concern for Takano et al., "Vital Role of the Calpain-Calpastatin System for Placental-Integrity-Dependent Embryonic Survival".

scientific article published on 13 November 2017

Filamin (FLN1),plexin (SEX), major palmitoylated proteinp55 (MPP1), and von-Hippel Lindau binding protein (VBP1) are not involved in incontinentia pigmenti type 2

scientific article published on 01 September 2000

Functional involvement of human discs large tumor suppressor in cytokinesis

scientific article published on 15 August 2008

Gene disruption of dematin causes precipitous loss of erythrocyte membrane stability and severe hemolytic anemia

scientific article published on 12 April 2016

Genetic inactivation of calpain-1 attenuates pain sensitivity in a humanized mouse model of sickle cell disease

scientific article published on 14 July 2016

Glutamate receptors localize postsynaptically at neuromuscular junctions in mice

scientific article

Gα13 Switch Region 2 Binds to the Talin Head Domain and Activates αIIbβ3 Integrin in Human Platelets

scientific article

Gα13 Switch Region 2 Relieves Talin Autoinhibition to Activate αIIbβ3 Integrin

scientific article published in November 2016

HIV protease inhibitors block parasite signal peptide peptidases and prevent growth of Babesia microti parasites in erythrocytes

scientific article published on 13 July 2019

Headpiece Domain of Dematin Regulates Calcium Mobilization and Signaling in Platelets ⬇️

scientific article published on October 11, 2012

Headpiece domain of dematin is required for the stability of the erythrocyte membrane

scientific article

Hemozoin Regulates iNOS Expression by Modulating the Transcription Factor NF-κB in Macrophages.

scientific article

Human Dlg protein binds to the envelope glycoproteins of human T-cell leukemia virus type 1 and regulates envelope mediated cell-cell fusion in T lymphocytes

scientific article

Human erythrocyte band 3 functions as a receptor for the sialic acid-independent invasion of Plasmodium falciparum. Role of the RhopH3-MSP1 complex ⬇️

scientific article (publication date: December 2014)

Human erythrocyte band 3 is a host receptor for glutamic acid-rich protein

scientific article published on 13 December 2018

Identification of a specific region of Plasmodium falciparum EBL-1 that binds to host receptor glycophorin B and inhibits merozoite invasion in human red blood cells ⬇️

scientific article

Identification of erythrocyte p55/MPP1 as a binding partner of NF2 tumor suppressor protein/Merlin

scientific article

Kinesin-73 Is a Processive Motor That Localizes to Rab5-containing Organelles ⬇️

scientific article published on December 18, 2010

LDL receptor related protein 1 requires the I3 domain of discs-large homolog 1/DLG1 for interaction with the kinesin motor protein KIF13B

scientific article published on 02 September 2019

Lack of phenotype for LTP and fear conditioning learning in calpain 1 knock-out mice

scientific article

Leukocyte Calpain Deficiency Reduces Angiotensin II-Induced Inflammation and Atherosclerosis But Not Abdominal Aortic Aneurysms in Mice

scientific article published on 10 March 2016

MPP1/p55 gene deletion in a hemophilia A patient with ectrodactyly and severe developmental defects

article

Malaria selectively targets pregnancy receptors

scientific article published in January 2015

Merozoite surface protein 1 recognition of host glycophorin A mediates malaria parasite invasion of red blood cells

scientific article (publication date: 23 April 2015)

Novel Peptidomimetic Cysteine Protease Inhibitors as Potential Antimalarial Agents

scientific article published on 01 June 2006

Pharmacological inhibition of calpain-1 prevents red cell dehydration and reduces Gardos channel activity in a mouse model of sickle cell disease

scientific article published on 19 October 2012

Phosphorylation-independent dual-site binding of the FHA domain of KIF13 mediates phosphoinositide transport via centaurin  1

scientific article

Plasmodium falciparum cysteine protease falcipain-2 cleaves erythrocyte membrane skeletal proteins at late stages of parasite development

scientific article

Plasmodium falciparum signal peptide peptidase cleaves malaria heat shock protein 101 (HSP101). Implications for gametocytogenesis

scientific article (publication date: 8 August 2014)

Plasmodium falciparum signal peptide peptidase is a promising drug target against blood stage malaria

scientific article published on 25 January 2009

Protein 4.1-mediated membrane targeting of human discs large in epithelial cells

scientific article

Proteomic and functional analyses of the periodic membrane skeleton in neurons

scientific article published on 09 June 2022

Purification of the NF2 tumor suppressor protein from human erythrocytes

scientific article published on 01 November 2006

Receptor-Independent Cardiac Protein Kinase Cα Activation by Calpain-Mediated Truncation of Regulatory Domains ⬇️

scientific article published on August 5, 2010

Receptor-based identification of an inhibitory peptide against blood stage malaria

scientific article

Regulatory models of RhoA suppression by dematin, a cytoskeletal adaptor protein

scientific article published on 7 April 2009

Role of mu-calpain in proteolytic cleavage of brain L-glutamic acid decarboxylase

scientific article published on 4 March 2008

Targeted Gene Inactivation of Calpain-1 Suppresses Cortical Degeneration Due to Traumatic Brain Injury and Neuronal Apoptosis Induced by Oxidative Stress ⬇️

scientific article published on February 24, 2012

The Drosophila miR-310 cluster negatively regulates synaptic strength at the neuromuscular junction

scientific article

The NMR structure of dematin headpiece reveals a dynamic loop that is conformationally altered upon phosphorylation at a distal site

scientific article

The effector domain of human Dlg tumor suppressor acts as a switch that relieves autoinhibition of kinesin-3 motor GAKIN/KIF13B.

scientific article

The headpiece domain of dematin regulates cell shape, motility, and wound healing by modulating RhoA activation

scientific journal article

Transglutaminase‐Mediated Remodeling of the Human Erythrocyte Membrane Skeleton: Relevance for Erythrocyte Diseases with Shortened Cell Lifespan ⬇️

scientific article published on January 1, 2011

Transport of PIP3 by GAKIN, a kinesin-3 family protein, regulates neuronal cell polarity

scientific article

Two Plasmodium falciparum merozoite proteins binding to erythrocyte band 3 form a direct complex

scientific article published on 2 November 2005

Tyrosine phosphorylation of the integrin beta 3 subunit regulates beta 3 cleavage by calpain

scientific article

Vital Role of the Calpain-Calpastatin System for Placental-Integrity-Dependent Embryonic Survival ⬇️

scientific article published on July 26, 2011

[Transport of PIP3 mediated by kinesin regulates neuronal cell polarity]

scientific article published on 01 July 2007

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