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List of works by Sibylle Grad

A Nucleotomy Model with Intact Annulus Fibrosus to Test Intervertebral Disc Regeneration Strategies.

scientific article

A combination of shear and dynamic compression leads to mechanically induced chondrogenesis of human mesenchymal stem cells ⬇️

scientific article published on October 11, 2011

A phenotypic comparison of intervertebral disc and articular cartilage cells in the rat.

scientific article published on 5 September 2007

A single-cell transcriptome of mesenchymal stromal cells to fabricate bioactive hydroxyapatite materials for bone regeneration

scientific article published on 11 August 2021

Advancing the cellular and molecular therapy for intervertebral disc disease

scientific article published on 30 June 2014

An injectable cross-linked scaffold for nucleus pulposus regeneration

scientific article

An injectable vehicle for nucleus pulposus cell-based therapy.

scientific article

An intervertebral disc whole organ culture system to investigate proinflammatory and degenerative disc disease condition.

scientific article published on 10 January 2018

Angiopoietin-1 receptor Tie2 distinguishes multipotent differentiation capability in bovine coccygeal nucleus pulposus cells

scientific article published on 23 May 2016

Anti-Inflammatory and Chondroprotective Effects of Vanillic Acid and Epimedin C in Human Osteoarthritic Chondrocytes

scientific article published on 19 June 2020

Association of the asporin D14 allele with lumbar-disc degeneration in Asians

scientific article published on 21 February 2008

Autologous Chondrocyte Implantation in Osteoarthritic Surroundings: TNFα and Its Inhibition by Adalimumab in a Knee-Specific Bioreactor

scientific article published in November 2017

Bioprinting Tissue Analogues with Decellularized Extracellular Matrix Bioink for Regeneration and Tissue Models of Cartilage and Intervertebral Discs

scientific article published in 2020

Bioreactor-Induced Chondrocyte Maturation Is Dependent on Cell Passage and Onset of Loading

scientific article

CD146 defines commitment of cultured annulus fibrosus cells to express a contractile phenotype

scientific article published on 8 June 2016

Cells and biomaterials in cartilage tissue engineering.

scientific article published on January 2009

Chondrocyte gene expression under applied surface motion.

scientific article published in January 2006

Chondrocytes seeded onto poly (L/DL-lactide) 80%/20% porous scaffolds: a biochemical evaluation

scientific article published in September 2003

Confocal imaging protocols for live/dead staining in three-dimensional carriers.

scientific article

Critical aspects and challenges for intervertebral disc repair and regeneration-Harnessing advances in tissue engineering

scientific article published on 30 July 2018

Defining the phenotype of young healthy nucleus pulposus cells: recommendations of the Spine Research Interest Group at the 2014 annual ORS meeting

scientific article

Differential phenotype of intervertebral disc cells: microarray and immunohistochemical analysis of canine nucleus pulposus and anulus fibrosus

scientific article published in June 2009

Differential response of human bone marrow stromal cells to either TGF-β(1) or rhGDF-5.

scientific article

Diversity of intervertebral disc cells: phenotype and function

scientific article

Effect of cyclic mechanical loading on immunoinflammatory microenvironment in biofabricating hydroxyapatite scaffold for bone regeneration

scientific article published on 09 March 2021

Effect of reduced oxygen tension and long-term mechanical stimulation on chondrocyte-polymer constructs.

scientific article published on 24 October 2007

Effects of Level, Loading Rate, Injury and Repair on Biomechanical Response of Ovine Cervical Intervertebral Discs

scientific article published on 20 June 2018

Effects of immobilization and dynamic compression on intervertebral disc cell gene expression in vivo

scientific article published in May 2003

Effects of simple and complex motion patterns on gene expression of chondrocytes seeded in 3D scaffolds

scientific article published in November 2006

Endogenous cell homing for intervertebral disk regeneration.

scientific article published on April 2015

Enhanced chondrogenic phenotype of primary bovine articular chondrocytes in Fibrin-Hyaluronan hydrogel by multi-axial mechanical loading and FGF18

scientific article published on 23 January 2020

Evaluation of biomimetic hyaluronic-based hydrogels with enhanced endogenous cell recruitment and cartilage matrix formation

scientific article published on 11 November 2019

Exhaustion of nucleus pulposus progenitor cells with ageing and degeneration of the intervertebral disc

scientific article published on January 2012

Farnesol-modified biodegradable polyurethanes for cartilage tissue engineering

scientific article published in January 2010

Fibrin-polyurethane composites for articular cartilage tissue engineering: a preliminary analysis

scientific article published in September 2005

Gene Expression Profiling Identifies Interferon Signalling Molecules and IGFBP3 in Human Degenerative Annulus Fibrosus

scientific article

Homing of mesenchymal stem cells in induced degenerative intervertebral discs in a whole organ culture system.

scientific article published in October 2012

Hyaluronan supplementation as a mechanical regulator of cartilage tissue development under joint-kinematic-mimicking loading.

scientific article published in August 2017

Hypoxic stress enhances extension and branching of dorsal root ganglion neuronal outgrowth

scientific article published on 04 May 2020

Identification and Characterization of Serum microRNAs as Biomarkers for Human Disc Degeneration: An RNA Sequencing Analysis

scientific article published on 08 December 2020

Induction of osteogenic differentiation by nanostructured alumina surfaces

scientific article published in May 2014

Influence of extremely low frequency, low energy electromagnetic fields and combined mechanical stimulation on chondrocytes in 3-D constructs for cartilage tissue engineering

scientific article published on 6 November 2013

Injectable hyaluronic acid down-regulates interferon signaling molecules, IGFBP3 and IFIT3 in the bovine intervertebral disc.

scientific article published on 18 December 2016

Injectable thermoreversible hyaluronan-based hydrogels for nucleus pulposus cell encapsulation

scientific article published on 27 August 2011

Intervertebral disc organ culture for the investigation of disc pathology and regeneration - benefits, limitations, and future directions of bioreactors

scientific article published on 26 September 2019

Isolation and characterisation of a recombinant antibody fragment that binds NCAM1-expressing intervertebral disc cells.

scientific article published on 13 December 2013

Isolation of high-quality RNA from intervertebral disc tissue via pronase predigestion and tissue pulverization

scientific article published on 19 June 2018

Mechanical Stress Inhibits Early Stages of Endogenous Cell Migration: A Pilot Study in an Ex Vivo Osteochondral Model

scientific article published on 06 August 2020

Mechanical and biological characterization of a composite annulus fibrosus repair strategy in an endplate delamination model

scientific article published on 16 July 2020

Mechanically stimulated osteochondral organ culture for evaluation of biomaterials in cartilage repair studies

article

Mesenchymal Stem/Stromal Cells seeded on cartilaginous endplates promote Intervertebral Disc Regeneration through Extracellular Matrix Remodeling.

scientific article published on 22 September 2016

Migration of bone marrow-derived cells for endogenous repair in a new tail-looping disc degeneration model in the mouse: a pilot study

scientific article published on 24 November 2014

Morphological and biomechanical effects of annulus fibrosus injury and repair in an ovine cervical model

scientific article published on 21 December 2019

Neoepitope fragments as biomarkers for different phenotypes of intervertebral disc degeneration

scientific article published in 2022

Organ culture bioreactors--platforms to study human intervertebral disc degeneration and regenerative therapy.

scientific article published on January 2015

Particulate cartilage under bioreactor-induced compression and shear

scientific article

Physical stimulation of chondrogenic cells in vitro: a review

scientific article published on October 2011

Physicobiochemical synergism through gene therapy and functional tissue engineering for in vitro chondrogenesis

scientific article

Physiological cartilage tissue engineering effect of oxygen and biomechanics

scientific article published on January 2011

Poly(γ-glutamic acid) and poly(γ-glutamic acid)-based nanocomplexes enhance type II collagen production in intervertebral disc.

scientific article published on 24 November 2016

Polyurethane scaffold with in situ swelling capacity for nucleus pulposus replacement.

scientific article published on 21 January 2016

Potential and limitations of intervertebral disc endogenous repair.

scientific article

Proinflammatory intervertebral disc cell and organ culture models induced by tumor necrosis factor alpha

scientific article published on 19 June 2020

Role of hypoxia and growth and differentiation factor-5 on differentiation of human mesenchymal stem cells towards intervertebral nucleus pulposus-like cells ⬇️

scientific article published on June 20, 2011

Strongly Enhanced Serum Levels of Vascular Endothelial Growth Factor (VEGF) after Poly-trauma and Burn ⬇️

scientific article published on 01 June 1998

Successful fishing for nucleus pulposus progenitor cells of the intervertebral disc across species

scientific article published on 27 June 2018

Surface motion upregulates superficial zone protein and hyaluronan production in chondrocyte-seeded three-dimensional scaffolds

scientific article published in January 2005

The combined effects of limited nutrition and high-frequency loading on intervertebral discs with endplates.

scientific article published in September 2010

The effect of sliding velocity on chondrocytes activity in 3D scaffolds

scientific article published on 18 January 2009

The roles and perspectives of microRNAs as biomarkers for intervertebral disc degeneration

scientific article published on 3 March 2017

The use of biodegradable polyurethane scaffolds for cartilage tissue engineering: potential and limitations

scientific article published in December 2003

Thermoreversible hyaluronan-based hydrogel supports in vitro and ex vivo disc-like differentiation of human mesenchymal stem cells.

scientific article published on 3 July 2013

Transcriptional profiling of intervertebral disc in a post-traumatic early degeneration organ culture model

scientific article published on 08 April 2021

Uncovering the secretome of mesenchymal stromal cells exposed to healthy, traumatic, and degenerative intervertebral discs: a proteomic analysis

scientific article published on 07 January 2021

Vascular endothelial growth factor serum level is strongly enhanced after burn injury and correlated with local and general tissue edema

scientific article

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