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List of works by Michael Emerman

A CRISPR screen for factors regulating SAMHD1 degradation identifies IFITMs as potent inhibitors of lentiviral particle delivery

scientific article published on 20 March 2018

A Plea for Justice for Jailed Medical Workers

scientific article published in Science

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

scientific article published on 30 April 2020

A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing

journal article from 'bioRxiv' published in 2020

A Single Nucleotide Polymorphism in Human APOBEC3C Enhances Restriction of Lentiviruses

scientific article

A novel Bayesian method for detection of APOBEC3-mediated hypermutation and its application to zoonotic transmission of simian foamy viruses

scientific article

A virus-packageable CRISPR screen identifies host factors mediating interferon inhibition of HIV

article

APOBEC3C Tandem Domain Proteins Create Super Restriction Factors against HIV-1

scientific article published on 28 April 2020

Activation of the DNA Damage Response Is a Conserved Function of HIV-1 and HIV-2 Vpr That Is Independent of SLX4 Recruitment

scientific article published on 13 September 2016

Adaptive evolution and antiviral activity of the conserved mammalian cytidine deaminase APOBEC3H.

scientific article

Advances in HIV molecular biology

scientific article published on January 1, 2002

An evolutionary perspective on the broad antiviral specificity of MxA

scientific article published on May 28, 2013

An evolutionary screen highlights canonical and noncanonical candidate antiviral genes within the primate TRIM gene family

scientific article (publication date: 2013)

An expanded clade of rodent Trim5 genes

scientific article published on 15 January 2009

Ancient adaptive evolution of tetherin shaped the functions of Vpu and Nef in human immunodeficiency virus and primate lentiviruses.

scientific article

Ancient adaptive evolution of the primate antiviral DNA-editing enzyme APOBEC3G

scientific article

Antagonism of SAMHD1 is actively maintained in natural infections of simian immunodeficiency virus

scientific article published on 09 December 2013

Antiretroelement activity of APOBEC3H was lost twice in recent human evolution

scientific article

Binding of Human Immunodeficiency Virus Type 1 to Immature Dendritic Cells Can Occur Independently of DC-SIGN and Mannose Binding C-Type Lectin Receptors via a Cholesterol-Dependent Pathway

scientific article published on December 1, 2003

Birth, decay, and reconstruction of an ancient TRIMCyp gene fusion in primate genomes

scientific article (publication date: 12 February 2013)

Capsid is a dominant determinant of retrovirus infectivity in nondividing cells

scientific article

Cellular restriction targeting viral capsids perturbs human immunodeficiency virus type 1 infection of nondividing cells

scientific article

Combinatorial mutagenesis of rapidly evolving residues yields super-restrictor antiviral proteins

scientific article published on 01 October 2019

Conservation and Innovation of APOBEC3A Restriction Functions during Primate Evolution

scientific article published on 6 April 2016

Controlling lentiviruses: single amino acid changes can determine specificity

scholarly article

Convergence and Divergence in the Evolution of the APOBEC3G-Vif Interaction Reveal Ancient Origins of Simian Immunodeficiency Viruses

scientific article published on January 24, 2013

Cyclophilin A interacts with diverse lentiviral capsids

scientific article published on 12 October 2006

Cytidine deaminase efficiency of the lentiviral viral restriction factor APOBEC3C correlates with dimerization.

scientific article

Dendritic cell-mediated viral transfer to T cells is required for human immunodeficiency virus type 1 persistence in the face of rapid cell turnover

scientific article

Determinants of cyclophilin A-dependent TRIM5 alpha restriction against HIV-1

scientific article

Discordant evolution of the adjacent antiretroviral genes TRIM22 and TRIM5 in mammals

scientific article

Evidence for a cytopathogenicity determinant in HIV-1 Vpr.

scientific article

Evidence for direct involvement of the capsid protein in HIV infection of nondividing cells

scientific article

Evolution-guided identification of antiviral specificity determinants in the broadly acting interferon-induced innate immunity factor MxA.

scientific article published on October 2012

Evolutionary Analyses Suggest a Function of MxB Immunity Proteins Beyond Lentivirus Restriction

scientific article

Evolutionary conflicts between viruses and restriction factors shape immunity

scientific article

Evolutionary toggling of Vpx/Vpr specificity results in divergent recognition of the restriction factor SAMHD1.

scientific article

Gene loss and adaptation to hominids underlie the ancient origin of HIV-1.

scientific article published on July 2013

Genetic drift of HIV populations in culture

scientific article

Going for the watchman

scientific article published on June 29, 2011

Guidelines for naming nonprimate APOBEC3 genes and proteins

scientific article

HIV-1 Vpr does not inhibit CTL-mediated apoptosis of HIV-1 infected cells

scientific article published on March 2002

HIV-1 infection of non-dividing cells

scientific article published in Nature

High-frequency persistence of an impaired allele of the retroviral defense gene TRIM5alpha in humans

scientific article published on January 2006

Host gene evolution traces the evolutionary history of ancient primate lentiviruses

scientific article (publication date: 19 September 2013)

How TRIM5alpha defends against retroviral invasions

scholarly article

Human Trim5α has additional activities that are uncoupled from retroviral capsid recognition

scientific article published on 28 October 2010

Identification and antiviral activity of common polymorphisms in the APOBEC3 locus in human populations

scientific article published on 10 June 2013

Identification of postentry restrictions to Mason-Pfizer monkey virus infection in New World monkey cells

scientific article published on 17 September 2008

Macaque interferon-induced transmembrane proteins limit replication of SHIV strains in an Envelope-dependent manner

scientific article published on 01 July 2019

Mutational resilience of antiviral restriction favors primate TRIM5α in host-virus evolutionary arms races

scientific article published on 15 September 2020

Natural polymorphisms in human APOBEC3H and HIV-1 Vif combine in primary T lymphocytes to affect viral G-to-A mutation levels and infectivity

scientific article

Paleovirology - ghosts and gifts of viruses past

scientific article (publication date: October 2011)

Paleovirology--modern consequences of ancient viruses

scientific article published in February 2010

Polymorphism in Human APOBEC3H Affects a Phenotype Dominant for Subcellular Localization and Antiviral Activity

scientific article published on June 8, 2011

Polymorphisms in Human APOBEC3H Differentially Regulate Ubiquitination and Antiviral Activity

scientific article published on 30 March 2020

Positive selection and increased antiviral activity associated with the PARP-containing isoform of human zinc-finger antiviral protein

scientific article

Positive selection of primate TRIM5alpha identifies a critical species-specific retroviral restriction domain

scientific article (publication date: 22 February 2005)

Primary isolates of human immunodeficiency virus type 1 are usually dominated by the major variants found in blood

scientific article

Reassessment of the roles of integrase and the central DNA flap in human immunodeficiency virus type 1 nuclear import

scientific article

Recurrent Loss of APOBEC3H Activity during Primate Evolution

scientific article published on 16 August 2018

Restriction of an extinct retrovirus by the human TRIM5alpha antiviral protein

scientific article

Retroviral DNA integration: viral and cellular determinants of target-site selection

scientific article published on 23 June 2006

Retroviral infection of non-dividing cells: old and new perspectives

scientific article

Simian immunodeficiency virus SIVagm from African green monkeys does not antagonize endogenous levels of African green monkey tetherin/BST-2.

scientific article published on 02 September 2009

Simian immunodeficiency virus variants that differ in pathogenicity differ in fitness under rapid cell turnover conditions

scientific article published on December 2005

TRIM34 restricts HIV-1 and SIV capsids in a TRIM5α-dependent manner

scientific article published on 13 April 2020

The DEAD-box RNA helicase DDX6 is required for efficient encapsidation of a retroviral genome

scientific article

The Little Book of Viruses

scientific article (publication date: 6 September 2011)

The Role of the Antiviral APOBEC3 Gene Family in Protecting Chimpanzees against Lentiviruses from Monkeys

scientific article

The ability of primate lentiviruses to degrade the monocyte restriction factor SAMHD1 preceded the birth of the viral accessory protein Vpx.

scientific article published on 26 January 2012

The breadth of antiviral activity of Apobec3DE in chimpanzees has been driven by positive selection

scientific article published on 10 August 2011

The cell cycle independence of HIV infections is not determined by known karyophilic viral elements

scientific article

The function and evolution of the restriction factor Viperin in primates was not driven by lentiviruses

scientific article

The host restriction factor APOBEC3G and retroviral Vif protein coevolve due to ongoing genetic conflict

scientific article published on January 2012

The human immunodeficiency virus Vpr protein binds Cdc25C: implications for G2 arrest

scientific article published in January 2004

The mongoose, the pheasant, the pox, and the retrovirus

scientific article (publication date: 2013)

The range of human APOBEC3H sensitivity to lentiviral Vif proteins

scientific article

Trim5 TAKes on pattern recognition

scientific article published in May 2011

Uracil DNA glycosylase is dispensable for human immunodeficiency virus type 1 replication and does not contribute to the antiviral effects of the cytidine deaminase Apobec3G.

scientific article

Visualization of the intracellular behavior of HIV in living cells

scientific article

Vpx overcomes a SAMHD1-independent block to HIV reverse transcription that is specific to resting CD4 T cells.

scientific article published on 22 February 2017