Search filters

List of works by Sebastiaan Eeltink

A comprehensive study to protein retention in hydrophobic interaction chromatography.

scientific article published on 12 May 2016

A cyclic-olefin-copolymer microfluidic immobilized-enzyme reactor for rapid digestion of proteins from dried blood spots

scientific article published on 28 January 2017

A generic approach to post-column refocusing in liquid chromatography.

scientific article published in August 2014

Advances in Ultrahigh-Pressure Liquid Chromatography Technology and System Design.

scientific article published on 24 November 2015

Advances in native high-performance liquid chromatography and intact mass spectrometry for the characterization of biopharmaceutical products.

scientific article published on 9 October 2017

Advances in organic polymer-based monolithic column technology for high-resolution liquid chromatography-mass spectrometry profiling of antibodies, intact proteins, oligonucleotides, and peptides

scientific article published on 4 January 2017

Applicability of linear and nonlinear retention-time models for reversed-phase liquid chromatography separations of small molecules, peptides, and intact proteins.

scientific article published in February 2016

Aqueous size-exclusion chromatographic separations of intact proteins under native conditions: Effect of pressure on selectivity and efficiency.

scientific article published on 9 November 2015

Characterization of polymer monolithic columns for small-molecule separations using total-pore-blocking conditions

scientific article

Characterization of polymer-based monolithic capillary columns by inverse size-exclusion chromatography and mercury-intrusion porosimetry

scientific article

Chromatographic Properties of Minimal Aspect Ratio Monolithic Silica Columns

scientific article

Comparison of the efficiency of microparticulate and monolithic capillary columns

scientific article

Comprehensive study of the macropore and mesopore size distributions in polymer monoliths using complementary physical characterization techniques and liquid chromatography.

scientific article published on 5 October 2016

Design and evaluation of microfluidic devices for two-dimensional spatial separations

scientific article published on 6 January 2016

Design and performance evaluation of a microfluidic ion-suppression module for anion-exchange chromatography

scientific article published on 12 June 2014

Design of a microfluidic device for comprehensive spatial two-dimensional liquid chromatography

scientific article published on 9 March 2015

Development of an ion-exchange chromatography method for monitoring the degradation of prebiotic arabinoxylan-oligosaccharides in a complex fermentation medium

scientific article published on 3 May 2013

Effect of gradient steepness on the kinetic performance limits and peak compression for reversed-phase gradient separations of small molecules.

scientific article published on 17 July 2015

Effect of polyethylene glycol on pore structure and separation efficiency of silica-based monolithic capillary columns

scientific article published on 7 March 2016

Enhancing detection sensitivity in gradient liquid chromatography via post-column refocusing and strong-solvent remobilization.

scientific article published on 25 May 2016

Exploring the pressure resistance limits of monolithic silica capillary columns

scientific article published on 4 April 2016

Extending the limits of operating pressure of narrow-bore column liquid chromatography instrumentation.

scientific article published on 26 April 2014

Fabrication and chromatographic performance of porous-shell pillar-array columns

scientific article published on September 2010

Fundamentals for LC miniaturization

scientific article published on 07 December 2012

Generic approach to the method development of intact protein separations using hydrophobic interaction chromatography.

scientific article published on 27 November 2017

Gradient-elution parameters in capillary liquid chromatography for high-speed separations of peptides and intact proteins

scientific article published on 7 June 2014

High-speed gradient separations of peptides and proteins using polymer-monolithic poly(styrene-co-divinylbenzene) capillary columns at ultra-high pressure

scientific article published on 13 July 2013

High-speed isocratic and gradient liquid-chromatography separations at 1500bar.

scientific article published on 14 July 2015

In-line system containing porous polymer monoliths for protein digestion with immobilized pepsin, peptide preconcentration and nano-liquid chromatography separation coupled to electrospray ionization mass spectroscopy

scientific article published on 29 February 2008

Kinetic performance optimisation for liquid chromatography: principles and practice.

scientific article

Kinetic plot based comparison of the efficiency and peak capacity of high-performance liquid chromatography columns: theoretical background and selected examples

scientific article published on 10 August 2011

Maximizing the peak capacity using coupled columns packed with 2.6 μm core-shell particles operated at 1200 bar.

scientific article published on 20 July 2012

Microfluidic membrane suppressor module design and evaluation for capillary ion chromatography

scientific article published on 29 December 2016

Monolithic porous polymer stationary phases in polyimide chips for the fast high-performance liquid chromatography separation of proteins and peptides

scientific article published on 15 March 2008

Open-tubular capillary columns with a porous layer of monolithic polymer for highly efficient and fast separations in electrochromatography

scientific article published in November 2006

Optimization of the porous structure and polarity of polymethacrylate-based monolithic capillary columns for the LC-MS separation of enzymatic digests

scientific article

Optimizing the peak capacity per unit time in one-dimensional and off-line two-dimensional liquid chromatography for the separation of complex peptide samples.

scientific article published on 5 March 2009

Peak refocusing using subsequent retentive trapping and strong eluent remobilization in liquid chromatography: a theoretical optimization study

scientific article published on 7 January 2015

Performance limits of monolithic and packed capillary columns in high-performance liquid chromatography and capillary electrochromatography

scientific article published on 20 December 2005

Post-polymerization photografting on methacrylate-based monoliths for separation of intact proteins and protein digests with comprehensive two-dimensional liquid chromatography hyphenated with high-resolution mass spectrometry

scientific article published on 24 March 2015

Potential of poly(styrene-co-divinylbenzene) monolithic columns for the LC-MS analysis of protein digests

scientific article

Practical aspects of using methacrylate-ester-based monolithic columns in capillary electrochromatography

scientific article published on 26 September 2005

Prototyping of a Microfluidic Modulator Chip and Its Application in Heart-Cut Strong-Cation-Exchange-Reversed-Phase Liquid Chromatography Coupled to Nanoelectrospray Mass Spectrometry for Targeted Proteomics

scientific article published on 13 January 2020

Prototyping of thermoplastic microfluidic chips and their application in high-performance liquid chromatography separations of small molecules

scientific article published in June 2017

Recent advances in the control of morphology and surface chemistry of porous polymer-based monolithic stationary phases and their application in CEC.

scientific article published on January 2007

Recent applications in capillary electrochromatography

scientific article published on December 2003

Resolving power in liquid chromatography: A trade-off between efficiency and analysis time

scientific article published on 10 October 2018

Separations using a porous-shell pillar array column on a capillary LC instrument.

scientific article published on 2 July 2012

Stability and repeatability of capillary columns based on porous monoliths of poly(butyl methacrylate-co-ethylene dimethacrylate).

scientific article published on 19 December 2006

Study of the influence of the aspect ratio on efficiency, flow resistance and retention factors of packed capillary columns in pressure- and electrically-driven liquid chromatography.

scientific article published in July 2004

Tailoring the morphology of methacrylate ester-based monoliths for optimum efficiency in liquid chromatography

scientific article

Towards ultra-high peak capacities and peak-production rates using spatial three-dimensional liquid chromatography

scientific article published on 23 October 2015

Ultra-High-Pressure Ion Chromatography with Suppressed Conductivity Detection at 70 MPa Using Columns Packed with 2.5 μm Anion-Exchange Particles

scientific article published on 23 October 2019

Very high efficiency porous silica layer open-tubular capillary columns produced via in-column sol-gel processing.

scientific article published on 19 September 2016

Visualization procedures for proteins and peptides on flat-bed monoliths and their effects on matrix-assisted laser-desorption/ionization time-of-flight mass spectrometric detection

scientific article