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List of works by Martina Kluth

13q deletion is linked to an adverse phenotype and poor prognosis in prostate cancer

scientific article published on 20 August 2018

5q21 deletion is often heterogeneous in prostate cancer

scientific article published on 24 January 2019

8p deletions in renal cell carcinoma are associated with unfavorable tumor features and poor overall survival

scientific article published on 19 November 2019

A non-diploid DNA status is linked to poor prognosis in renal cell cancer

scientific article published on 02 May 2020

A nuclear shift of GSK3β protein is an independent prognostic factor in prostate cancer

Aberrant expression of membranous carbonic anhydrase IX (CAIX) is associated with unfavorable disease course in papillary and clear cell renal cell carcinoma

scientific article published on 12 October 2018

Aberrant expression of the microtubule-associated protein tau is an independent prognostic feature in prostate cancer

scientific article published on 01 March 2019

Apurinic/apyrimidinic endonuclease 1 (APE1/Ref-1) overexpression is an independent prognostic marker in prostate cancer without TMPRSS2:ERG fusion.

scientific article published on 3 May 2017

Aquaporin 5 expression is frequent in prostate cancer and shows a dichotomous correlation with tumor phenotype and PSA recurrence

scientific article published on 22 October 2015

Author Correction: Up regulation and nuclear translocation of Y-box binding protein 1 (YB-1) is linked to poor prognosis in ERG-negative prostate cancer

scientific article published in Scientific Reports

CHD1 is a 5q21 tumor suppressor required for ERG rearrangement in prostate cancer.

scientific article

Chromosomal deletion of 9p21 is linked to poor patient prognosis in papillary and clear cell kidney cancer

scientific article published on 30 March 2020

Chromosome 17p13 deletion is associated with an aggressive tumor phenotype in clear cell renal cell carcinoma

scientific article published on 13 June 2020

Chromosome 5 harbors two independent deletion hotspots at 5q13 and 5q21 that characterize biologically different subsets of aggressive prostate cancer

scientific article published on 12 October 2020

Claudin-1 upregulation is associated with favorable tumor features and a reduced risk for biochemical recurrence in ERG-positive prostate cancer

scientific article published on 19 November 2019

Clinical significance of different types of p53 gene alteration in surgically treated prostate cancer

scientific article published on 26 April 2014

Correction: Genomic deletion of chromosome 12p is an independent prognostic marker in prostate cancer

scientific article published on January 2017

Cytoplasmic Accumulation of Sequestosome 1 (p62) Is a Predictor of Biochemical Recurrence, Rapid Tumor Cell Proliferation, and Genomic Instability in Prostate Cancer

scientific article published on 29 April 2015

Cytoplasmic accumulation of ELAVL1 is an independent predictor of biochemical recurrence associated with genomic instability in prostate cancer

scientific article published on 02 November 2015

Deletion lengthening at chromosomes 6q and 16q targets multiple tumor suppressor genes and is associated with an increasingly poor prognosis in prostate cancer

scientific article published on 11 November 2017

Deletion of 18q is a strong and independent prognostic feature in prostate cancer

scientific article published on 16 November 2016

Deletion of 3p13 is a late event linked to progression of : fusion prostate cancer

Deletion of 8p is an independent prognostic parameter in prostate cancer

scientific article published on 17 November 2016

Development and Characterization of a Spontaneously Metastatic Patient-Derived Xenograft Model of Human Prostate Cancer

scientific article published in Scientific Reports

Expression of CCCTC-binding factor (CTCF) is linked to poor prognosis in prostate cancer

scientific article published on 29 November 2019

Expression of DNA ligase IV is linked to poor prognosis and characterizes a subset of prostate cancers harboring TMPRSS2:ERG fusion and PTEN deletion

scientific article

Expression of the immune checkpoint receptor TIGIT in Hodgkin's lymphoma

scientific article published on 04 December 2018

Expression of the immune checkpoint receptor TIGIT in seminoma

scientific article published on 31 May 2019

FOXA1 expression is a strong independent predictor of early PSA recurrence in ERG negative prostate cancers treated by radical prostatectomy

scientific article

Family with sequence similarity 13C (FAM13C) overexpression is an independent prognostic marker in prostate cancer

scientific article

Genomic deletion of chromosome 12p is an independent prognostic marker in prostate cancer

scientific article published on 21 July 2015

HDAC1 overexpression independently predicts biochemical recurrence and is associated with rapid tumor cell proliferation and genomic instability in prostate cancer.

scientific article published on 18 March 2015

Heterogeneity of ERG expression in prostate cancer: a large section mapping study of entire prostatectomy specimens from 125 patients.

scientific article

High B7-H3 expression is linked to increased risk of prostate cancer progression

scientific article published on 10 August 2020

High BCAR1 expression is associated with early PSA recurrence in ERG negative prostate cancer

scientific article

High concordance of TMPRSS-ERG fusion between primary prostate cancer and its lymph node metastases

High homogeneity of MMR deficiency in ovarian cancer

scientific article published on 08 January 2020

High homogeneity of mismatch repair deficiency in advanced prostate cancer

scientific article published on 06 December 2019

High level of EZH2 expression is linked to high density of CD8-positive T-lymphocytes and an aggressive phenotype in renal cell carcinoma

scientific article published on 17 April 2020

High nuclear karyopherin α 2 expression is a strong and independent predictor of biochemical recurrence in prostate cancer patients treated by radical prostatectomy

scientific article published on 26 July 2013

High-Level Glyoxalase 1 (GLO1) expression is linked to poor prognosis in prostate cancer.

scientific article published on 19 September 2017

High-Level HOOK3 Expression Is an Independent Predictor of Poor Prognosis Associated with Genomic Instability in Prostate Cancer

scientific article published on 31 July 2015

High-Level γ-Glutamyl-Hydrolase (GGH) Expression is Linked to Poor Prognosis in ERG Negative Prostate Cancer

scientific article published on 29 January 2017

Homogeneous MMR Deficiency Throughout the Entire Tumor Mass Occurs in a Subset of Colorectal Neuroendocrine Carcinomas

scientific article published on 06 March 2020

Immunohistochemically detected IDH1R132H mutation is rare and mostly heterogeneous in prostate cancer

scientific article published on 9 February 2018

Increased ERCC1 expression is linked to chromosomal aberrations and adverse tumor biology in prostate cancer

scientific article

Integrative genomic analyses reveal an androgen-driven somatic alteration landscape in early-onset prostate cancer

scientific article

Loss of CCAAT-enhancer-binding protein alpha (CEBPA) is linked to poor prognosis in PTEN deleted and TMPRSS2:ERG fusion type prostate cancers

scientific article published on 14 November 2018

Loss of PSP94 expression is associated with early PSA recurrence and deteriorates outcome of PTEN deleted prostate cancers

scientific article published on 01 May 2019

Loss of SOX9 Expression Is Associated with PSA Recurrence in ERG-Positive and PTEN Deleted Prostate Cancers

scientific article published on June 2015

Loss of the adhesion molecule CEACAM1 is associated with early biochemical recurrence in TMPRSS2:ERG fusion-positive prostate cancers

scientific article published on 09 March 2020

MMR Deficiency is Homogeneous in Pancreatic Carcinoma and Associated with High Density of Cd8-Positive Lymphocytes

scientific article published on 27 February 2020

MMR deficiency in urothelial carcinoma of the bladder presents with temporal and spatial homogeneity throughout the tumor mass

scientific article published on 14 February 2020

Molecular Evolution of Early-Onset Prostate Cancer Identifies Molecular Risk Markers and Clinical Trajectories

scientific article published on 01 December 2018

Nuclear ELAC2 overexpression is associated with increased hazard for relapse after radical prostatectomy

scientific article published on 13 August 2019

Overexpression of enhancer of zeste homolog 2 (EZH2) characterizes an aggressive subset of prostate cancers and predicts patient prognosis independently from pre- and postoperatively assessed clinicopathological parameters

scientific article published on 21 September 2015

Overexpression of the A Disintegrin and Metalloproteinase ADAM15 is linked to a Small but Highly Aggressive Subset of Prostate Cancers

scientific article published on 07 March 2017

Overexpression of thymidylate synthase (TYMS) is associated with aggressive tumor features and early PSA recurrence in prostate cancer

scientific article published on April 2015

PSCA expression is associated with favorable tumor features and reduced PSA recurrence in operated prostate cancer.

scientific article

Patterns of TIGIT Expression in Lymphatic Tissue, Inflammation, and Cancer

scientific article published on 10 January 2019

Prevalence and clinical significance of VHL mutations and 3p25 deletions in renal tumor subtypes

scientific article published on 21 January 2020

Prognostic and diagnostic role of PSA immunohistochemistry: A tissue microarray study on 21,000 normal and cancerous tissues

scientific article published on 10 September 2019

Reduced AZGP1 expression is an independent predictor of early PSA recurrence and associated with ERG-fusion positive and PTEN deleted prostate cancers

scientific article published on 18 September 2015

Reduced KLK2 expression is a strong and independent predictor of poor prognosis in ERG-negative prostate cancer

scientific article published on 06 July 2020

SPINK1 expression is tightly linked to 6q15- and 5q21-deleted ERG-fusion negative prostate cancers but unrelated to PSA recurrence

scientific article published on 10 July 2013

The Combination of DNA Ploidy Status and PTEN/6q15 Deletions Provides Strong and Independent Prognostic Information in Prostate Cancer

scientific article published on 26 January 2016

The prognostic value of SUMO1/Sentrin specific peptidase 1 (SENP1) in prostate cancer is limited to ERG-fusion positive tumors lacking PTEN deletion

scientific article published on 23 July 2015

Up regulation and nuclear translocation of Y-box binding protein 1 (YB-1) is linked to poor prognosis in ERG-negative prostate cancer

scientific article published on 17 May 2017

Up regulation of the steroid hormone synthesis regulator HSD3B2 is linked to early PSA recurrence in prostate cancer

scientific article published on 24 May 2018

Up-regulation of Biglycan is Associated with Poor Prognosis and PTEN Deletion in Patients with Prostate Cancer

scientific article published on 19 August 2017

Up-regulation of mismatch repair genes MSH6, PMS2 and MLH1 parallels development of genetic instability and is linked to tumor aggressiveness and early PSA recurrence in prostate cancer

scientific article published in November 2016

Upregulation of centromere protein F is linked to aggressive prostate cancers

Upregulation of the heterogeneous nuclear ribonucleoprotein hnRNPA1 is an independent predictor of early biochemical recurrence in TMPRSS2:ERG fusion-negative prostate cancers

scientific article published on 16 May 2020

VEGFR-1 overexpression identifies a small subgroup of aggressive prostate cancers in patients treated by prostatectomy

scientific article published on 16 April 2015

p16 upregulation is linked to poor prognosis in ERG negative prostate cancer.

scientific article published on 21 July 2016