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List of works by William B Isaacs

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AR-V7 and Resistance to Enzalutamide and Abiraterone in Prostate Cancer

scientific article published on September 3, 2014
Inflammation in prostate carcinogenesis

scientific article published on April 2007
Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24.

scientific article published in April 2007
Ligand-independent androgen receptor variants derived from splicing of cryptic exons signify hormone-refractory prostate cancer

scientific article
The evolutionary history of lethal metastatic prostate cancer

scientific article published on April 2015
Prostate cancer

scientific article published on 01 July 2003
Cumulative association of five genetic variants with prostate cancer

scientific article published on 16 January 2008
Copy number analysis indicates monoclonal origin of lethal metastatic prostate cancer

scientific article
Androgen-induced TOP2B-mediated double-strand breaks and prostate cancer gene rearrangements

scientific article published on 4 July 2010
Distinct transcriptional programs mediated by the ligand-dependent full-length androgen receptor and its splice variants in castration-resistant prostate cancer.

scientific article
Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer

scientific journal article
Evidence for a prostate cancer susceptibility locus on the X chromosome

article
Germline mutations in HOXB13 and prostate-cancer risk

scientific article
REVEL: An Ensemble Method for Predicting the Pathogenicity of Rare Missense Variants

scientific article published on 21 September 2016
Hypermethylation of CpG islands in primary and metastatic human prostate cancer.

scientific article
A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer

scientific article published on 14 September 2014
Phenotypic analysis of prostate-infiltrating lymphocytes reveals TH17 and Treg skewing

scientific article published on June 2008
Tracking the clonal origin of lethal prostate cancer

scientific article published on 25 October 2013
Nuclear MYC protein overexpression is an early alteration in human prostate carcinogenesis

scientific article
The landscape of recombination in African Americans

scientific article
Two genome-wide association studies of aggressive prostate cancer implicate putative prostate tumor suppressor gene DAB2IP

scientific article published on 11 December 2007
Pathological and molecular aspects of prostate cancer

scientific article
Identification of a new prostate cancer susceptibility locus on chromosome 8q24.

scientific article
Prostate carcinogenesis and inflammation: emerging insights.

scientific article published on 21 October 2004
Germline mutations and sequence variants of the macrophage scavenger receptor 1 gene are associated with prostate cancer risk

scientific article (publication date: October 2002)
Cyclooxygenases in cancer: progress and perspective

scientific article (publication date: 8 November 2004)
Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes

scientific article
PTEN protein loss by immunostaining: analytic validation and prognostic indicator for a high risk surgical cohort of prostate cancer patients

scientific article published on 30 August 2011
Alpha-methylacyl-CoA racemase: a new molecular marker for prostate cancer.

scientific article
DNA methylation alterations exhibit intraindividual stability and interindividual heterogeneity in prostate cancer metastases

scientific article published on January 2013
The role of inflammation in the pathogenesis of prostate cancer

scientific article
Genome-wide association study of prostate cancer in men of African ancestry identifies a susceptibility locus at 17q21.

scientific article
Evidence for two independent prostate cancer risk-associated loci in the HNF1B gene at 17q12

scientific article
Rb Loss Is Characteristic of Prostatic Small Cell Neuroendocrine Carcinoma

scientific article published on December 9, 2013
A snapshot of the expression signature of androgen receptor splicing variants and their distinctive transcriptional activities

scientific article
Genome-wide association study identifies new prostate cancer susceptibility loci

scientific journal article
Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer

scientific article
A Germline DNA Polymorphism Enhances Alternative Splicing of theKLF6Tumor Suppressor Gene and Is Associated with Increased Prostate Cancer Risk

article
Human prostate-infiltrating CD8+ T lymphocytes are oligoclonal and PD-1+.

scientific article
DNA hypomethylation arises later in prostate cancer progression than CpG island hypermethylation and contributes to metastatic tumor heterogeneity.

scientific article
Sequence variants of toll-like receptor 4 are associated with prostate cancer risk: results from the CAncer Prostate in Sweden Study

scientific article
DNA copy number alterations in prostate cancers: a combined analysis of published CGH studies

scientific article published in May 2007
A combined genomewide linkage scan of 1,233 families for prostate cancer-susceptibility genes conducted by the international consortium for prostate cancer genetics

scientific article
A molecular analysis of prokaryotic and viral DNA sequences in prostate tissue from patients with prostate cancer indicates the presence of multiple and diverse microorganisms

scientific article
CYP3A4-V and prostate cancer in African Americans: causal or confounding association because of population stratification?

scientific article published on 7 May 2002
Pathological and molecular mechanisms of prostate carcinogenesis: implications for diagnosis, detection, prevention, and treatment

scientific article published on February 2004
HOXB13 is a susceptibility gene for prostate cancer: results from the International Consortium for Prostate Cancer Genetics (ICPCG).

scientific article published on 12 October 2012
In vitro evidence for complex modes of nuclear beta-catenin signaling during prostate growth and tumorigenesis

scientific article published in April 2002
Human polymorphisms at long non-coding RNAs (lncRNAs) and association with prostate cancer risk

scientific article
Association between two unlinked loci at 8q24 and prostate cancer risk among European Americans

scientific article published on 9 October 2007

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