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List of works by William B Isaacs

A Genome-Wide Assessment of Variability in Human Serum Metabolism

article

A Germline DNA Polymorphism Enhances Alternative Splicing of theKLF6Tumor Suppressor Gene and Is Associated with Increased Prostate Cancer Risk

article

A Germline Variant at 8q24 Contributes to Familial Clustering of Prostate Cancer in Men of African Ancestry

scientific article published on 11 May 2020

A combined genomewide linkage scan of 1,233 families for prostate cancer-susceptibility genes conducted by the international consortium for prostate cancer genetics

scientific article

A comprehensive association study for genes in inflammation pathway provides support for their roles in prostate cancer risk in the CAPS study

scientific article published on 01 October 2006

A comprehensive evaluation of CHEK2 germline mutations in men with prostate cancer

scientific article published on 09 March 2018

A genetic variant near GATA3 implicated in inherited susceptibility and etiology of benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS).

scientific article published on 28 June 2017

A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants

scientific journal article

A genome-wide survey over the ChIP-on-chip identified androgen receptor-binding genomic regions identifies a novel prostate cancer susceptibility locus at 12q13.13.

scientific article published on 29 September 2011

A major locus for hereditary prostate cancer in Finland: localization by linkage disequilibrium of a haplotype in the HPCX region

scientific article published on 20 May 2005

A major locus for hereditary prostate cancer in Finland: localization by linkage disequilibrium of a haplotype in the HPCX region

scholarly article by Agnes B. Baffoe-Bonnie et al published 22 October 2005 in Human Genetics

A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer

scientific article published on 14 September 2014

A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease

scientific article

A molecular analysis of prokaryotic and viral DNA sequences in prostate tissue from patients with prostate cancer indicates the presence of multiple and diverse microorganisms

scientific article

A multigenic approach to evaluating prostate cancer risk in a systematic replication study

scientific article

A novel prostate cancer susceptibility locus at 19q13

scientific article

A novel role of myosin VI in human prostate cancer

scientific article published on November 2006

A peripheral circulating TH1 cytokine profile is inversely associated with prostate cancer risk in CLUE II.

scientific article

A polymorphism in the CDKN1B gene is associated with increased risk of hereditary prostate cancer

scientific article

A snapshot of the expression signature of androgen receptor splicing variants and their distinctive transcriptional activities

scientific article

AIM1 is an actin-binding protein that suppresses cell migration and micrometastatic dissemination

scientific article published on 26 July 2017

AR-V7 and resistance to enzalutamide and abiraterone in prostate cancer

scientific article

Abstract 1642: Rare missense variants inMAP3K14andARHGAP27in men with hereditary prostate cancer

Abstract 2564: Identification of a novel SPOP missense mutation from targeted next-generation sequencing of men with chromosome 17-q linkage

Abstract 3883: Clonal evolution of a lethal prostate cancer: Integrated whole genome analysis case study

Abstract B40: Rare variant discovery in known cancer genes from whole-exome sequencingof African American hereditary prostate cancer families

article

Acne and risk of prostate cancer

scientific article

Acute inflammatory proteins constitute the organic matrix of prostatic corpora amylacea and calculi in men with prostate cancer

scholarly article

Adding genetic risk score to family history identifies twice as many high-risk men for prostate cancer: Results from the prostate cancer prevention trial

scientific article

Alpha-methylacyl-CoA racemase as an androgen-independent growth modifier in prostate cancer.

scientific article

Alpha-methylacyl-CoA racemase: a new molecular marker for prostate cancer.

scientific article

Alpha-methylacyl-CoA racemase: a variably sensitive immunohistochemical marker for the diagnosis of small prostate cancer foci on needle biopsy

scientific article published on August 2003

An evaluation of PCR primer sets used for detection of Propionibacterium acnes in prostate tissue samples

scientific article published on 01 October 2008

Analysis of Xq27-28 linkage in the international consortium for prostate cancer genetics (ICPCG) families ⬇️

scientific article published on June 19, 2012

Analytic, Preanalytic, and Clinical Validation of p53 IHC for Detection of TP53 Missense Mutation in Prostate Cancer

scientific article published on 26 April 2017

Androgen receptor outwits prostate cancer drugs

scientific article

Androgen-induced TOP2B-mediated double-strand breaks and prostate cancer gene rearrangements

scientific article published on 4 July 2010

Appraising the relevance of DNA copy number loss and gain in prostate cancer using whole genome DNA sequence data

scientific article published on 25 September 2017

Assembly of inflammation-related genes for pathway-focused genetic analysis

scientific article (publication date: 17 October 2007)

Association analysis of 9,560 prostate cancer cases from the International Consortium of Prostate Cancer Genetics confirms the role of reported prostate cancer associated SNPs for familial disease

scientific article published on 26 October 2013

Association between sequence variants at 17q12 and 17q24.3 and prostate cancer risk in European and African Americans

scientific article

Association between two unlinked loci at 8q24 and prostate cancer risk among European Americans

scientific article published on 9 October 2007

Association between variants in genes involved in the immune response and prostate cancer risk in men randomized to the finasteride arm in the Prostate Cancer Prevention Trial

scientific article published on 20 March 2017

Association of 17 prostate cancer susceptibility loci with prostate cancer risk in Chinese men.

scientific article

Association of CASP8 D302H polymorphism with reduced risk of aggressive prostate carcinoma

scientific article

Association of IL10 and other immune response- and obesity-related genes with prostate cancer in CLUE II.

scientific article

Association of a germ-line copy number variation at 2p24.3 and risk for aggressive prostate cancer

scientific article published on 03 March 2009

Association of prostate cancer risk variants with clinicopathologic characteristics of the disease

scientific article

Association of prostate cancer risk with snps in regions containing androgen receptor binding sites captured by ChIP‐On‐chip analyses ⬇️

scientific article published on June 10, 2011

Association of reported prostate cancer risk alleles with PSA levels among men without a diagnosis of prostate cancer

scientific article

Associations between hOGG1 sequence variants and prostate cancer susceptibility

scientific article published in April 2002

Associations of prostate cancer risk variants with disease aggressiveness: results of the NCI-SPORE Genetics Working Group analysis of 18,343 cases

scientific article

Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation

scientific article published on 7 April 2016

CD38 is methylated in prostate cancer and regulates extracellular NAD

scientific article published on 21 September 2018

COX-2 gene promoter haplotypes and prostate cancer risk

scientific article published on 30 January 2004

CYP3A4-V and prostate cancer in African Americans: causal or confounding association because of population stratification?

scientific article published on 7 May 2002

Cadherin-6: a new prognostic marker for renal cell carcinoma

scientific article published in January 2004

Carbohydrate restriction, prostate cancer growth, and the insulin-like growth factor axis

scientific article

Characterizing genetic risk at known prostate cancer susceptibility loci in African Americans

scientific article

Chromosome 8q24 risk variants in hereditary and non-hereditary prostate cancer patients

scientific article published on 01 April 2008

Chromosomes 4 and 8 implicated in a genome wide SNP linkage scan of 762 prostate cancer families collected by the ICPCG

scientific article published on 11 July 2011

Common sequence variants of the macrophage scavenger receptor 1 gene are associated with prostate cancer risk

scientific article

Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer

scientific journal article

Comparison of two methods for estimating absolute risk of prostate cancer based on single nucleotide polymorphisms and family history

scientific article

Compelling evidence for a prostate cancer gene at 22q12.3 by the International Consortium for Prostate Cancer Genetics

scientific article published on 03 May 2007

Comprehensive assessment of DNA copy number alterations in human prostate cancers using Affymetrix 100K SNP mapping array

scientific article

Comprehensive genetic evaluation of common E-cadherin sequence variants and prostate cancer risk: strong confirmation of functional promoter SNP.

scientific article

Comprehensive mutational analysis and mRNA isoform quantification of TP63 in normal and neoplastic human prostate cells

scientific article

Concept and benchmarks for assessing narrow-sense validity of genetic risk score values

scientific article published on 29 April 2019

Constitutively active androgen receptor splice variants AR-V3, AR-V7 and AR-V9 are co-expressed in castration-resistant prostate cancer metastases

scientific article published on 10 July 2018

Copy number analysis indicates monoclonal origin of lethal metastatic prostate cancer

scientific article

Cumulative association of five genetic variants with prostate cancer

scientific article published on 16 January 2008

Cumulative effect of five genetic variants on prostate cancer risk in multiple study populations

scientific article

Cyclin D1 Loss Distinguishes Prostatic Small-Cell Carcinoma from Most Prostatic Adenocarcinomas

scientific article published on 5 August 2015

Cyclooxygenases in cancer: progress and perspective

scientific article (publication date: 8 November 2004)

Cytokine profiling of prostatic fluid from cancerous prostate glands identifies cytokines associated with extent of tumor and inflammation.

scientific article published in June 2008

DIAPH3 governs the cellular transition to the amoeboid tumour phenotype ⬇️

scientific article published on May 16, 2012

DNA copy number alterations in prostate cancers: a combined analysis of published CGH studies

scientific article published in May 2007

DNA hypomethylation arises later in prostate cancer progression than CpG island hypermethylation and contributes to metastatic tumor heterogeneity.

scientific article

DNA methylation alterations exhibit intraindividual stability and interindividual heterogeneity in prostate cancer metastases

scientific article published on January 2013

Decreased gene expression of steroid 5 alpha-reductase 2 in human prostate cancer: implications for finasteride therapy of prostate carcinoma

scientific article published in October 2003

Deletion of a small consensus region at 6q15, including the MAP3K7 gene, is significantly associated with high-grade prostate cancers

scientific article published on 01 September 2007

Design, synthesis, and in vitro testing of alpha-methylacyl-CoA racemase inhibitors

scientific article published on 04 May 2007

Differences in inherited risk among relatives of hereditary prostate cancer patients using genetic risk score

scientific article published on 19 June 2018

Distinct transcriptional programs mediated by the ligand-dependent full-length androgen receptor and its splice variants in castration-resistant prostate cancer.

scientific article

Do environmental factors modify the genetic risk of prostate cancer?

scientific article

Does diabetes mellitus modify the association between 17q12 risk variant and prostate cancer aggressiveness?

scientific article

Dynamic structure of the SPANX gene cluster mapped to the prostate cancer susceptibility locus HPCX at Xq27

scientific article

Effects of RNase L mutations associated with prostate cancer on apoptosis induced by 2',5'-oligoadenylates ⬇️

scientific article published on October 15, 2003

Endoglin (CD105) as a urinary and serum marker of prostate cancer

scientific article

Erratum: Copy number analysis indicates monoclonal origin of lethal metastatic prostate cancer

article

Established prostate cancer susceptibility variants are not associated with disease outcome

scientific article

Estimation of absolute risk for prostate cancer using genetic markers and family history

scientific article published on October 2009

Evaluation of DLC1 as a prostate cancer susceptibility gene: mutation screen and association study

scientific article

Evaluation of PPP2R2A as a prostate cancer susceptibility gene: a comprehensive germline and somatic study

scientific article published on July 2011

Evaluation of SRD5A2 sequence variants in susceptibility to hereditary and sporadic prostate cancer ⬇️

scientific article published on June 15, 2003

Evaluation of association of HNF1B variants with diverse cancers: collaborative analysis of data from 19 genome-wide association studies

scientific article

Evidence for a general cancer susceptibility locus at 3p24 in families with hereditary prostate cancer

scientific article published on 01 March 2005

Evidence for a prostate cancer susceptibility locus on the X chromosome.

article

Evidence for two independent prostate cancer risk-associated loci in the HNF1B gene at 17q12

scientific article

Explaining racial differences in prostate cancer in the United States: sociology or biology?

scientific article published in February 2005

Expression mapping at 12p12-13 in advanced prostate carcinoma

scientific article published on May 2004

Familial aggregation of bothersome benign prostatic hyperplasia symptoms

scientific article published in April 2003

Family-based samples can play an important role in genetic association studies

scientific article published on September 2008

Feasibility and performance of a novel probe panel to detect somatic DNA copy number alterations in clinical specimens for predicting prostate cancer progression

scientific article published on 17 August 2020

Fine mapping association study and functional analysis implicate a SNP in MSMB at 10q11 as a causal variant for prostate cancer risk

scientific article published on 19 January 2009

Fine mapping of a region of chromosome 11q13 reveals multiple independent loci associated with risk of prostate cancer

scientific article

Fine-mapping and family-based association analyses of prostate cancer risk variants at Xp11.

scientific article published on 23 June 2009

Fine-mapping the putative chromosome 17q21–22 prostate cancer susceptibility gene to a 10 cM region based on linkage analysis

article

Focus on prostate cancer.

scientific article

Functional annotation of risk loci identified through genome-wide association studies for prostate cancer

scientific article

GOLPH2 and MYO6: putative prostate cancer markers localized to the Golgi apparatus.

scientific article

Gene expression signature of benign prostatic hyperplasia revealed by cDNA microarray analysis

scientific article (publication date: 15 May 2002)

Generalizability of established prostate cancer risk variants in men of African ancestry

scientific article

Genetic and epigenetic inactivation of LPL gene in human prostate cancer

scientific article published on February 2009

Genetic and epigenetic inactivation of TNFRSF10C in human prostate cancer

scientific article published on February 2009

Genetic factors influencing prostate cancer risk in Norwegian men.

scientific article published on 27 November 2017

Genetic markers associated with early cancer-specific mortality following prostatectomy

scientific article

Genetic variability in inflammation pathways and prostate cancer risk

scientific article published on May 2007

Genetic variants and family history predict prostate cancer similar to prostate-specific antigen

scientific article

Genetic variants in cell cycle control pathway confer susceptibility to aggressive prostate carcinoma

scientific article published on 28 December 2015

Genetic variants in the LEPR, CRY1, RNASEL, IL4, and ARVCF genes are prognostic markers of prostate cancer-specific mortality

scientific article

Genome-wide association of familial prostate cancer cases identifies evidence for a rare segregating haplotype at 8q24.21.

scientific article published on 4 June 2016

Genome-wide association scan for variants associated with early-onset prostate cancer

scientific article

Genome-wide association study identifies a new locus JMJD1C at 10q21 that may influence serum androgen levels in men.

scientific article published on 30 August 2012

Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24.

scientific article published in April 2007

Genome-wide association study identifies genetic determinants of urine PCA3 levels in men.

scientific article published on April 2013

Genome-wide association study identifies loci at ATF7IP and KLK2 associated with percentage of circulating free PSA.

scientific article published on January 2013

Genome-wide association study identifies new prostate cancer susceptibility loci

scientific journal article

Genome-wide association study of prostate cancer in men of African ancestry identifies a susceptibility locus at 17q21.

scientific article

Genome-wide copy-number variation analysis identifies common genetic variants at 20p13 associated with aggressiveness of prostate cancer

scientific article

Genome-wide expression analysis of recently processed formalin-fixed paraffin embedded human prostate tissues

scientific article published in February 2009

Genome-wide linkage analysis of 1,233 prostate cancer pedigrees from the International Consortium for Prostate Cancer Genetics using novel sumLINK and sumLOD analyses

scientific article

Genome-wide scan of 29,141 African Americans finds no evidence of directional selection since admixture

scientific article

Genome-wide screen for prostate cancer susceptibility genes in men with clinically significant disease

scientific article

Genome-wide two-locus epistasis scans in prostate cancer using two European populations

scientific article published on 26 February 2012

Genome‐wide scan for prostate cancer susceptibility genes in the Johns Hopkins hereditary prostate cancer families ⬇️

scientific article published on December 1, 2003

Germ-line mutation of NKX3.1 cosegregates with hereditary prostate cancer and alters the homeodomain structure and function

scientific article published on 01 January 2006

Germ-line sequence variants of PTEN do not have an important role in hereditary and non-hereditary prostate cancer susceptibility

scientific article

Germline ATBF1 mutations and prostate cancer risk

scientific article (publication date: July 2006)

Germline BLM mutations and metastatic prostate cancer

scientific article published on 05 November 2019

Germline DNA-repair Gene Mutations and Outcomes in Men with Metastatic Castration-resistant Prostate Cancer Receiving First-line Abiraterone and Enzalutamide

scientific article published on 10 February 2018

Germline Mutations in ATM and BRCA1/2 Are Associated with Grade Reclassification in Men on Active Surveillance for Prostate Cancer

scientific article published on 08 October 2018

Germline Mutations in ATM and BRCA1/2 Distinguish Risk for Lethal and Indolent Prostate Cancer and are Associated with Early Age at Death

scientific article published on 9 December 2016

Germline Variants in Asporin Vary by Race, Modulate the Tumor Microenvironment, and Are Differentially Associated with Metastatic Prostate Cancer

scientific article

Germline copy number polymorphisms involving larger than 100 kb are uncommon in normal subjects

scientific article published on 01 February 2007

Germline mutations and sequence variants of the macrophage scavenger receptor 1 gene are associated with prostate cancer risk

scientific article (publication date: October 2002)

Germline mutations in DNA repair genes are associated with bladder cancer risk and unfavourable prognosis

scientific article published on 04 June 2018

Germline mutations in HOXB13 and prostate-cancer risk

scientific article

Germline mutations in PPFIBP2 are associated with lethal prostate cancer

scientific article published on 24 July 2018

Germline sequence variants of the LZTS1 gene are associated with prostate cancer risk

scientific article

Global patterns of prostate cancer incidence, aggressiveness, and mortality in men of african descent

scientific article published on 13 February 2013

H6D polymorphism in macrophage-inhibitory cytokine-1 gene associated with prostate cancer

scientific article

HOXB13 interaction with MEIS1 modifies proliferation and gene expression in prostate cancer

scientific article published on 17 December 2018

HOXB13 is a susceptibility gene for prostate cancer: results from the International Consortium for Prostate Cancer Genetics (ICPCG).

scientific article published on 12 October 2012

Homozygous deletions and recurrent amplifications implicate new genes involved in prostate cancer

scientific article published on August 2008

Human polymorphisms at long non-coding RNAs (lncRNAs) and association with prostate cancer risk

scientific article

Human prostate cancer precursors and pathobiology.

scientific article published on November 2003

Human prostate-infiltrating CD8+ T lymphocytes are oligoclonal and PD-1+.

scientific article

Hypermethylation of CpG islands in primary and metastatic human prostate cancer.

scientific article

Identification and characterization of novel SNPs in CHEK2 in Ashkenazi Jewish men with prostate cancer

scientific article

Identification of a new prostate cancer susceptibility locus on chromosome 8q24.

scientific article

Identification of a novel NBN truncating mutation in a family with hereditary prostate cancer ⬇️

scientific article

Identification of a novel germline SPOP mutation in a family with hereditary prostate cancer

scientific article

Identification of a prostate cancer susceptibility locus on chromosome 7q11-21 in Jewish families

scholarly article

Identification of aryl hydrocarbon receptor as a putative Wnt/beta-catenin pathway target gene in prostate cancer cells

scientific article published on April 2004

Identification of miR-30b-3p and miR-30d-5p as direct regulators of androgen receptor signaling in prostate cancer by complementary functional microRNA library screening

scientific article

Identification of new differentially methylated genes that have potential functional consequences in prostate cancer

scientific article

Immunomodulatory IL-18 binding protein is produced by prostate cancer cells and its levels in urine and serum correlate with tumor status.

scientific article published on 16 November 2010

Implementation of Germline Testing for Prostate Cancer: Philadelphia Prostate Cancer Consensus Conference 2019

scientific article published on 09 June 2020

Improved biomarkers for prostate cancer: a definite need

scientific article published in June 2004

In vitro evidence for complex modes of nuclear beta-catenin signaling during prostate growth and tumorigenesis

scientific article published in April 2002

Increased gene copy number of ERG on chromosome 21 but not TMPRSS2-ERG fusion predicts outcome in prostatic adenocarcinomas

scientific article published on 8 July 2011

Individual and cumulative effect of prostate cancer risk-associated variants on clinicopathologic variables in 5,895 prostate cancer patients

scientific article

Infections and inflammation in prostate cancer

scientific article

Infectious mononucleosis, other infections and prostate-specific antigen concentration as a marker of prostate involvement during infection.

scientific article published on 17 December 2015

Inflammation in prostate carcinogenesis

scientific article published on April 2007

Inflammation, Microbiota, and Prostate Cancer

scientific article

Inherited genetic markers discovered to date are able to identify a significant number of men at considerably elevated risk for prostate cancer

scientific article

Inherited genetic variant predisposes to aggressive but not indolent prostate cancer

scientific article

Inherited risk assessment of prostate cancer: it takes three to do it right

scientific article published on 15 August 2019

Insight into infection-mediated prostate damage: Contrasting patterns of C-reactive protein and prostate-specific antigen levels during infection

scientific article published on 12 July 2017

Integrated clinical, whole-genome, and transcriptome analysis of multisampled lethal metastatic prostate cancer.

scientific article published on May 2016

Integration of multiethnic fine-mapping and genomic annotation to prioritize candidate functional SNPs at prostate cancer susceptibility regions

scientific article

Integration of somatic deletion analysis of prostate cancers and germline linkage analysis of prostate cancer families reveals two small consensus regions for prostate cancer genes at 8p

scientific article published on 01 May 2007

Interaction effect of PTEN and CDKN1B chromosomal regions on prostate cancer linkage

scientific article published on 5 June 2004

Interactions of sequence variants in interleukin-1 receptor-associated kinase4 and the toll-like receptor 6-1-10 gene cluster increase prostate cancer risk

scientific article

Interleukin-6 sequence variants are not associated with prostate cancer risk

article

Intraductal/ductal histology and lymphovascular invasion are associated with germline DNA-repair gene mutations in prostate cancer

scientific article

Joint effect of HSD3B1 and HSD3B2 genes is associated with hereditary and sporadic prostate cancer susceptibility

scientific article published on 01 March 2002

Key genes involved in the immune response are generally not associated with intraprostatic inflammation in men without a prostate cancer diagnosis: Results from the prostate cancer prevention trial

scientific article published on 15 January 2016

Lactoferrin CpG Island Hypermethylation and Decoupling of mRNA and Protein Expression in the Early Stages of Prostate Carcinogenesis

scientific article published on 06 September 2019

Large-scale association analysis in Asians identifies new susceptibility loci for prostate cancer

scientific article

Large-scale fine mapping of the HNF1B locus and prostate cancer risk

scientific article

Leveraging population admixture to characterize the heritability of complex traits

scientific article

Ligand-independent androgen receptor variants derived from splicing of cryptic exons signify hormone-refractory prostate cancer

scientific article

Looking beyond morphology: cancer gene expression profiling using DNA microarrays

scientific article published on January 2003

Loss of PTEN is associated with aggressive behavior in ERG-positive prostate cancer

scientific article

MP69-12 ADDED VALUE OF GENETIC RISK SCORE TO THE PROSTATE CANCER PREVENTION TRIAL (PCPT) RISK CALCULATOR: FINDINGS FROM THE PCPT STUDY

MSH2 Loss in Primary Prostate Cancer

scientific article published on 8 August 2017

Macrophage inhibitory cytokine 1: a new prognostic marker in prostate cancer

scientific article published on 20 October 2009

Mannose Receptor-positive Macrophage Infiltration Correlates with Prostate Cancer Onset and Metastatic Castration-resistant Disease

scientific article published on 19 October 2018

Meta-analysis of association of rare mutations and common sequence variants in the MSR1 gene and prostate cancer risk

scientific article published on 01 May 2006

Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes

scientific article

Modulation of CXCL14 (BRAK) expression in prostate cancer

scientific article published in June 2005

Molecular Characterization and Clinical Outcomes of Primary Gleason Pattern 5 Prostate Cancer After Radical Prostatectomy

scientific article published on 26 July 2019

Molecular evidence that invasive adenocarcinoma can mimic prostatic intraepithelial neoplasia (PIN) and intraductal carcinoma through retrograde glandular colonization

scientific article

Molecular pathways to prostate cancer

scientific article published on December 2003

Molecular prostate cancer pathology: current issues and achievements.

scientific article

Monocyte chemotactic protein-1 (MCP-1/CCL2) is associated with prostatic growth dysregulation and benign prostatic hyperplasia

scientific article published on April 2010

Multiple genomic alterations on 21q22 predict various TMPRSS2/ERG fusion transcripts in human prostate cancers

scientific article published on 01 November 2007

Mutational analysis of ETV6 in prostate carcinoma

scientific article

Mutational analysis of PINX1 in hereditary prostate cancer.

scientific article

Mutational analysis of SPANX genes in families with X-linked prostate cancer

scientific article published on 01 June 2007

National Cancer Institute Prostate Cancer Genetics Workshop

scientific article

Nuclear MYC protein overexpression is an early alteration in human prostate carcinogenesis

scientific article

Nucleotide resolution analysis of TMPRSS2 and ERG rearrangements in prostate cancer ⬇️

scientific article published on June 1, 2013

Obesity and capsular incision at the time of open retropubic radical prostatectomy

scientific article published on November 2005

Obesity and risk of biochemical progression following radical prostatectomy at a tertiary care referral center

scientific article published on 01 September 2005

Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer

scientific article

PTEN protein loss by immunostaining: analytic validation and prognostic indicator for a high risk surgical cohort of prostate cancer patients

scientific article published on 30 August 2011

Pathological and molecular aspects of prostate cancer

scientific article

Pathological and molecular mechanisms of prostate carcinogenesis: implications for diagnosis, detection, prevention, and treatment

scientific article published on February 2004

Peripheral Zone Inflammation Is Not Strongly Associated With Lower Urinary Tract Symptom Incidence and Progression in the Placebo Arm of the Prostate Cancer Prevention Trial .

scientific article published on 21 June 2016

Peroxisomal branched chain fatty acid beta-oxidation pathway is upregulated in prostate cancer

scientific article

Phenotypic analysis of prostate-infiltrating lymphocytes reveals TH17 and Treg skewing

scientific article published on June 2008

Phenotypic characterization of telomerase-immortalized primary non-malignant and malignant tumor-derived human prostate epithelial cell lines

scientific article published on 17 January 2006

Physical and transcript map of the hereditary prostate cancer region at xq27.

scientific article

Polygenic risk score improves prostate cancer risk prediction: results from the Stockholm-1 cohort study

scientific article published on 18 January 2011

Polymorphic GGC repeats in the androgen receptor gene are associated with hereditary and sporadic prostate cancer risk

scientific article published on 23 January 2002

Polymorphic variants in α-methylacyl-CoA racemase and prostate cancer

article

Polymorphisms in the CYP1A1 gene are associated with prostate cancer risk

scientific article published in September 2003

Polymorphisms influencing prostate-specific antigen concentration may bias genome-wide association studies on prostate cancer

scientific article

Pooled genome linkage scan of aggressive prostate cancer: results from the International Consortium for Prostate Cancer Genetics

scientific article published on 25 August 2006

Post hoc Analysis for Detecting Individual Rare Variant Risk Associations Using Probit Regression Bayesian Variable Selection Methods in Case-Control Sequencing Studies

scientific article published on 17 June 2016

Potential impact of adding genetic markers to clinical parameters in predicting prostate biopsy outcomes in men following an initial negative biopsy: findings from the REDUCE trial

scientific article published on 12 May 2012

Prevalence of the HOXB13 G84E prostate cancer risk allele in men treated with radical prostatectomy

scientific article published on 05 March 2014

Prostate Cancer Susceptibility in Men of African Ancestry at 8q24

scientific article published on 27 January 2016

Prostate cancer

scientific article published on 01 July 2003

Prostate cancer detection on urinalysis for alpha methylacyl coenzyme a racemase protein

scientific article published on October 2004

Prostate cancer predisposition loci and risk of metastatic disease and prostate cancer recurrence

scientific article

Prostate cancer risk associated loci in African Americans

scientific article published on 23 June 2009

Prostate cancer risk-associated variants reported from genome-wide association studies: meta-analysis and their contribution to genetic Variation

scientific article

Prostate carcinogenesis and inflammation: emerging insights.

scientific article published on 21 October 2004

Prostate size and risk of high-grade, advanced prostate cancer and biochemical progression after radical prostatectomy: a search database study

scientific article published in October 2005

REVEL: An Ensemble Method for Predicting the Pathogenicity of Rare Missense Variants

scientific article published on 21 September 2016

RNASEL Arg462Gln polymorphism and prostate cancer in PLCO

article

Rare Germline Pathogenic Mutations of DNA Repair Genes Are Most Strongly Associated with Grade Group 5 Prostate Cancer

scientific article published on 13 January 2020

Rare Variation in TET2 Is Associated with Clinically Relevant Prostate Carcinoma in African Americans

scientific article published on 2 August 2016

Rb loss is characteristic of prostatic small cell neuroendocrine carcinoma

scientific article published on 9 December 2013

Refining the prostate cancer genetic association within the JAZF1 gene on chromosome 7p15.2.

scientific article

Role of Genetic Testing for Inherited Prostate Cancer Risk: Philadelphia Prostate Cancer Consensus Conference 2017.

scientific article

Role of the Nijmegen breakage syndrome 1 gene in familial and sporadic prostate cancer

scientific article published in May 2006

Screening for familial and hereditary prostate cancer

scientific article published on 5 December 2015

Sequence Variants in Toll-Like Receptor Gene Cluster (TLR6-TLR1-TLR10) and Prostate Cancer Risk

article

Sequence variants at 22q13 are associated with prostate cancer risk

scientific article published on January 2009

Sequence variants in the 3'-->5' deoxyribonuclease TREX2: identification in a genetic screen and effects on catalysis by the recombinant proteins

scientific article

Sequence variants in the human 25-hydroxyvitamin D3 1-alpha-hydroxylase (CYP27B1) gene are not associated with prostate cancer risk

scientific article published in November 2002

Sequence variants of alpha-methylacyl-CoA racemase are associated with prostate cancer risk

scientific article published on 01 November 2002

Sequence variants of toll-like receptor 4 are associated with prostate cancer risk: results from the CAncer Prostate in Sweden Study

scientific article

Sequence variation within the 5' regulatory regions of the vitamin D binding protein and receptor genes and prostate cancer risk

scientific article

Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets

scientific article published on 16 April 2018

Sexually transmitted infections and prostatic inflammation/cell damage as measured by serum prostate specific antigen concentration

scientific article published on May 2006

Single nucleotide polymorphisms and the likelihood of prostate cancer at a given prostate specific antigen level

scientific article

Single-Nucleotide Polymorphism-Based Genetic Risk Score and Patient Age at Prostate Cancer Diagnosis

scientific article published on 02 December 2019

Somatic molecular subtyping of prostate tumors from HOXB13 G84E carriers

scientific article

Specific detection of prostate cancer cells in urine by multiplex immunofluorescence cytology.

scientific article published on 14 April 2009

Stronger association between obesity and biochemical progression after radical prostatectomy among men treated in the last 10 years

scientific article published on 01 April 2005

Sustained influence of infections on prostate-specific antigen concentration: An analysis of changes over 10 years of follow-up

article

Systematic replication study of reported genetic associations in prostate cancer: Strong support for genetic variation in the androgen pathway

scientific article published on December 2006

TMPRSS2-ERG gene fusion status in minute (minimal) prostatic adenocarcinoma

scientific article published on 4 September 2009

Telomere length as a risk factor for hereditary prostate cancer

scientific article published on 28 November 2013

The G84E mutation of HOXB13 is associated with increased risk for prostate cancer: results from the REDUCE trial

scientific article published on 7 February 2013

The HOXB13 G84E Mutation Is Associated with an Increased Risk for Prostate Cancer and Other Malignancies

scientific article

The evolutionary history of lethal metastatic prostate cancer

scientific article published on April 2015

The expression of AURKA is androgen regulated in castration-resistant prostate cancer.

scientific article published on 21 December 2017

The interaction of four genes in the inflammation pathway significantly predicts prostate cancer risk

scientific article

The landscape of recombination in African Americans

scientific article

The role of genetic markers in the management of prostate cancer

scientific article published on 05 June 2012

The role of inflammation in the pathogenesis of prostate cancer

scientific article

Tracking the clonal origin of lethal prostate cancer

scientific article published on 25 October 2013

Transmission/disequilibrium tests of androgen receptor and glutathione S-transferase pi variants in prostate cancer families

scientific article

Trefoil factor 3 overexpression in prostatic carcinoma: prognostic importance using tissue microarrays

scientific article published in November 2004

Trichomonas vaginalis infection and prostate-specific antigen concentration: Insights into prostate involvement and prostate disease risk

scientific article published on 02 August 2019

Truncating variants in p53AIP1 disrupting DNA damage-induced apoptosis are associated with prostate cancer risk

scientific article published in November 2006

Two Novel Susceptibility Loci for Prostate Cancer in Men of African Ancestry.

scientific article published in August 2017

Two genome-wide association studies of aggressive prostate cancer implicate putative prostate tumor suppressor gene DAB2IP

scientific article published on 11 December 2007

Two independent prostate cancer risk-associated Loci at 11q13

scientific article

Two-locus genome-wide linkage scan for prostate cancer susceptibility genes with an interaction effect

article

Updated insights into genetic contribution to prostate cancer predisposition: focus on HOXB13

scientific article published on 01 October 2019

Use of Aspirin and Statins in Relation to Inflammation in Benign Prostate Tissue in the Placebo Arm of the Prostate Cancer Prevention Trial

scientific article published on 24 June 2020

Validation of a prostate cancer polygenic risk score

scientific article published on 17 August 2020

Validation of genome-wide prostate cancer associations in men of African descent

scientific article

Validation of prostate cancer risk-related loci identified from genome-wide association studies using family-based association analysis: evidence from the International Consortium for Prostate Cancer Genetics (ICPCG)

scientific article published on 25 December 2011

Variation in IL10 and other genes involved in the immune response and in oxidation and prostate cancer recurrence

scientific article

Variation in genes involved in the immune response and prostate cancer risk in the placebo arm of the Prostate Cancer Prevention Trial

scientific article

Viral infections and lower urinary tract symptoms in the third national health and nutrition examination survey

scientific article published on 17 September 2007

XMRV: A New Virus in Prostate Cancer? ⬇️

scientific article published on October 21, 2010

Xq27-28 deletions in prostate carcinoma

scientific article

gsSKAT: Rapid gene set analysis and multiple testing correction for rare-variant association studies using weighted linear kernels

scientific article published on 16 February 2017

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