Search filters

List of works by Robert Gatenby

A Mathematical Dissection of the Adaptation of Cell Populations to Fluctuating Oxygen Levels

scientific article published on 16 June 2020

A mathematical model of tumour and blood pHe regulation: The HCO3-/CO2 buffering system

scientific article

A microenvironmental model of carcinogenesis

scientific article published in January 2008

A multiscale model of the bone marrow and hematopoiesis

scientific article published on April 2011

A pharmacodynamic model of clinical synergy in multiple myeloma

scientific article published on 05 April 2020

A physical sciences network characterization of non-tumorigenic and metastatic cells

scientific article published on January 2013

A quantitative theoretical model for the development of malignancy in ductal carcinoma in situ

scientific article published on 31 October 2009

A simulation of parental and glycolytic tumor phenotype competition predicts observed responses to pH changes and increased glycolysis after anti-VEGF therapy

scientific article published in 2022

A theoretical quantitative model for evolution of cancer chemotherapy resistance

scientific article published on 20 April 2010

A unifying theory of carcinogenesis, and why targeted therapy doesn't work

scientific article published in September 2012

Abstract 793: Evolutionary therapy modeling for multidrug resistance: A novel concept of false drug

scientific article published in 2012

Acid treatment of melanoma cells selects for invasive phenotypes

scientific article

Acid-mediated tumor invasion: a multidisciplinary study

scientific article published on May 2006

Acidity generated by the tumor microenvironment drives local invasion

scientific article

Acidity promotes tumour progression by altering macrophage phenotype in prostate cancer

scientific article published on 16 August 2019

Adaptation to Stochastic Temporal Variations in Intratumoral Blood Flow: The Warburg Effect as a Bet Hedging Strategy

scientific article

Adaptation to Survival in Germinal Center Is the Initial Step in Onset of Indolent Stage of Multiple Myeloma ⬇️

scientific article published on October 12, 2011

Adaptive therapy.

scientific article

Aggregation Effects and Population-Based Dynamics as a Source of Therapy Resistance in Cancer

scientific article published in November 2016

Alternating synchronizability of complex clustered networks with regular local structure

scientific article published on 14 January 2008

An Ex Vivo Platform for the Prediction of Clinical Response in Multiple Myeloma.

scientific article published on 11 April 2017

An evolutionary model of carcinogenesis ⬇️

scientific article published on October 1, 2003

An integrated computational/experimental model of tumor invasion

scientific article published in February 2006

Ancient hot and cold genes and chemotherapy resistance emergence

scientific article

Application of Evolutionary Principles to Cancer Therapy

scientific article published on 2 November 2015

Application of information theory and extreme physical information to carcinogenesis

scientific article published on 01 July 2002

Application of quantitative models from population biology and evolutionary game theory to tumor therapeutic strategies.

scientific article published on September 2003

Artificial selection for host resistance to tumour growth and subsequent cancer cell adaptations: an evolutionary arms race

scientific article published on 07 October 2020

Automated Delineation of Lung Tumors from CT Images Using a Single Click Ensemble Segmentation Approach.

scientific article

Bayesian Framework to Augment Tumor Board Decision Making

scientific article published on 01 May 2021

Beyond mammography: new frontiers in breast cancer screening

scientific article

Bicarbonate increases tumor pH and inhibits spontaneous metastases

scientific article

Buffer Therapy for Cancer

scientific article published on August 2012

Cancer suppression by compression

scientific article published on 18 December 2014

Cancer treatment as a game: integrating evolutionary game theory into the optimal control of chemotherapy ⬇️

scientific article published on November 29, 2012

Cancer: an emergent property of disturbed resource-rich environments? Ecology meets personalized medicine

scientific article published on 26 March 2015

Characterizing the ecological and evolutionary dynamics of cancer

scientific article published on 27 July 2020

Chiral Monomers Ensure Orientational Specificity of Monomer Binding During Polymer Self-Replication

scientific article published on 03 May 2018

Chronic acidosis in the tumour microenvironment selects for overexpression of LAMP2 in the plasma membrane

scientific article

Comparative study between discrete and continuum models for the evolution of competing phenotype-structured cell populations in dynamical environments

scientific article published on 01 October 2020

Conditions for correspondence between Hartree scattering and biological growth

scientific article published in October 2008

Correction: Acidity promotes tumour progression by altering macrophage phenotype in prostate cancer

scientific article published on 01 March 2020

Coulomb interactions between cytoplasmic electric fields and phosphorylated messenger proteins optimize information flow in cells

scientific article

Cytoplasmic convection currents and intracellular temperature gradients

scientific article published on 04 November 2019

Darwinian Dynamics of Intratumoral Heterogeneity: Not Solely Random Mutations but Also Variable Environmental Selection Forces

scientific article published on 23 March 2016

Defining Cancer Subpopulations by Adaptive Strategies Rather Than Molecular Properties Provides Novel Insights into Intratumoral Evolution.

scientific article

Divergent and convergent evolution in metastases suggest treatment strategies based on specific metastatic sites

scientific article

Dynamics-based scalability of complex networks

scientific article published on 27 October 2008

ENvironmental Dynamics Underlying Responsive Extreme Survivors (ENDURES) of Glioblastoma: A Multidisciplinary Team-based, Multifactorial Analytical Approach

scientific article published on 01 August 2019

Eco-evolutionary causes and consequences of temporal changes in intratumoural blood flow

article

Episodic, transient systemic acidosis delays evolution of the malignant phenotype: Possible mechanism for cancer prevention by increased physical activity

scientific article

Eradicating Metastatic Cancer and the Eco-Evolutionary Dynamics of Anthropocene Extinctions

scientific article published on 26 November 2019

Evolution of Tumor Invasiveness: The Adaptive Tumor Microenvironment Landscape Model ⬇️

scientific article published on August 22, 2011

Evolutionary Dynamics in Cancer Therapy ⬇️

scientific article published on August 23, 2011

Evolutionary Ecology of Organs: A Missing Link in Cancer Development?

scientific article

Evolutionary advantage of directional symmetry breaking in self-replicating polymers.

scientific article published on 12 March 2018

Evolutionary approaches to prolong progression-free survival in breast cancer

scientific article

Evolutionary dynamics of cancer prevention

scientific article published on August 2010

Evolutionary dynamics of carcinogenesis and why targeted therapy does not work.

scientific article

Evolutionary dynamics of competing phenotype-structured populations in periodically fluctuating environments

scientific article published on 22 October 2019

Evolutionary perspective of cancer: myth, metaphors, and reality

scientific article published on 27 May 2015

Evolutionary strategy for systemic therapy of metastatic breast cancer: balancing response with suppression of resistance

scientific article

Exploiting evolution to treat drug resistance: combination therapy and the double bind

scientific article published on 19 March 2012

Exploiting evolutionary principles to prolong tumor control in preclinical models of breast cancer

scientific article published on February 2016

First Strike-Second Strike Strategies in Metastatic Cancer: Lessons from the Evolutionary Dynamics of Extinction

scientific article published on 20 June 2019

Free Base Lysine Increases Survival and Reduces Metastasis in Prostate Cancer Model.

scientific article

Glycolysis in cancer: a potential target for therapy.

scientific article published on 4 April 2007

Heterogeneity in intratumoral regions with rapid gadolinium washout correlates with estrogen receptor status and nodal metastasis

scientific article published on 17 April 2015

High School Internship Program in Integrated Mathematical Oncology (HIP IMO): Five-Year Experience at Moffitt Cancer Center

scientific article published on 09 July 2020

Hypoxia and adaptive landscapes in the evolution of carcinogenesis

scientific article published on June 2007

Identifying spatial imaging biomarkers of glioblastoma multiforme for survival group prediction.

scientific article published on 28 September 2016

Impact of metabolic heterogeneity on tumor growth, invasion, and treatment outcomes. ⬇️

scientific article

Information Dynamics in Living Systems: Prokaryotes, Eukaryotes, and Cancer ⬇️

scientific article published on July 19, 2011

Information dynamics in carcinogenesis and tumor growth

scientific article

Information theory in living systems, methods, applications, and challenges

scientific article published on 3 November 2006

Innovations in Diagnostic Imaging and the Transformation of the Clinical Practice of Radiology in Collaborative, Multidisciplinary Cancer Care

scientific article

Integrated imaging of cancer metabolism

scientific article published on August 2011

Integrating evolutionary dynamics into cancer therapy

scientific article published on 22 July 2020

Integrating evolutionary dynamics into treatment of metastatic castrate-resistant prostate cancer

scientific article

Integrating genetic and nongenetic drivers of somatic evolution during carcinogenesis: The biplane model

scientific article published on 13 May 2020

Intermittent hormonal therapy shows similar outcome than SOC in ER+ breast cancer preclinical model

article

Intermittent hypoxia selects for genotypes and phenotypes that increase survival, invasion, and therapy resistance

scientific article

Intracellular electric field and pH optimize protein localization and movement.

scientific article

Investigating Information Dynamics in Living Systems through the Structure and Function of Enzymes

scientific article

Is adaptive therapy natural?

article

Leaky vessels as a potential source of stromal acidification in tumours.

scientific article

Lessons from applied ecology: cancer control using an evolutionary double bind

scientific article published on 14 September 2009

Life history trade-offs in cancer evolution

scientific article (publication date: December 2013)

Mathematical modelling of tumour acidity

scientific article published on 7 August 2008

Mathematical oncology: cancer summed up.

scientific article published in January 2003

Metabolic changes during carcinogenesis: potential impact on invasiveness

scientific article published on 16 September 2006

Minimization of thermodynamic costs in cancer cell invasion

scientific article published on 14 January 2013

Mistic: An Open-Source <u>M</u>ultiplexed <u>I</u>mage <u>t-S</u>NE Viewer

scientific article published in 2021

Mistic: An open-source multiplexed image t-SNE viewer

scientific article published in 2022

Modelling a new angle on understanding cancer

scientific article published in December 2002

Molecular and Functional Imaging of Breast Cancer ⬇️

scientific article published on July 1, 2010

Morphologic instability and cancer invasion

scientific article published on October 2005

Multidrug Cancer Therapy in Metastatic Castrate-Resistant Prostate Cancer: An Evolution-Based Strategy

scientific article published on 16 April 2019

Multiparameter MRI Predictors of Long-Term Survival in Glioblastoma Multiforme

scientific article published on 01 March 2019

Multiscale modelling of vascular tumour growth in 3D: the roles of domain size and boundary conditions

scientific article (publication date: 2011)

Mutation-selection balance and compensatory mechanisms in tumour evolution

scientific article published on 30 November 2020

NCI Workshop Report: Clinical and Computational Requirements for Correlating Imaging Phenotypes with Genomics Signatures

scientific article

NIMG-21. SEX DIFFERENCES IN EXTREME SURVIVORSHIP AMONG PRIMARY GLIOBLASTOMA PATIENTS

Natural resistance to cancers: a Darwinian hypothesis to explain Peto's paradox

scientific article

Novel evolutionary dynamics of small populations in breast cancer adjuvant and neoadjuvant therapy

publication published on 11 March 2021

Obesity paradox in cancer: Is bigger really better?

scientific article published on 24 April 2019

Of cancer and cave fish

scientific article published on April 2011

Optimal control to develop therapeutic strategies for metastatic castrate resistant prostate cancer

scientific article published on 20 September 2018

Optimal control to reach eco-evolutionary stability in metastatic castrate-resistant prostate cancer

scientific article published on 08 December 2020

Optimization of synchronization in complex clustered networks

scientific article

Optimizing Cancer Treatment Using Game Theory: A Review

article

Order in a multidimensional system ⬇️

scientific article published on July 19, 2011

Pathology to enhance precision medicine in oncology: lessons from landscape ecology

scientific article published on July 2015

Predicting Malignant Nodules from Screening CT Scans.

scientific article published on 12 July 2016

Prediction of drug response in breast cancer using integrative experimental/computational modeling

scientific article published on 14 April 2009

Predictive oncology: a review of multidisciplinary, multiscale in silico modeling linking phenotype, morphology and growth

scientific article

Prostate-specific antigen dynamics predict individual responses to intermittent androgen deprivation

scientific article published on 09 April 2020

Publisher Correction: Mutation-selection balance and compensatory mechanisms in tumour evolution

scientific article published on 14 December 2020

Pyruvate sensitizes pancreatic tumors to hypoxia-activated prodrug TH-302.

scientific article

Quantitative computed tomographic descriptors associate tumor shape complexity and intratumor heterogeneity with prognosis in lung adenocarcinoma.

scientific article

Quantitative imaging in cancer evolution and ecology

scientific article

Radiologically defined ecological dynamics and clinical outcomes in glioblastoma multiforme: preliminary results

scientific article published on February 2014

Radiomics in Brain Tumor: Image Assessment, Quantitative Feature Descriptors, and Machine-Learning Approaches.

scientific article published on 5 October 2017

Radiomics: the process and the challenges

scientific article

Reduction of metastasis using a non-volatile buffer

scientific article

Regulation of the Warburg effect in early-passage breast cancer cells.

scientific article

Report on EU-USA workshop: how systems biology can advance cancer research (27 October 2008)

scientific article

Reproducibility and Prognosis of Quantitative Features Extracted from CT Images

scientific article published on February 2014

Riparian ecosystems in human cancers

scientific article

Searching for Goldilocks: How evolution and ecology can help uncover more effective patient-specific chemotherapies

scientific article published on 15 September 2020

Separation of metabolic supply and demand: aerobic glycolysis as a normal physiological response to fluctuating energetic demands in the membrane

scientific article published on 5 June 2014

Sex-specific impact of patterns of imageable tumor growth on survival of primary glioblastoma patients

scientific article published on 19 May 2020

Spatial heterogeneity and evolutionary dynamics modulate time to recurrence in continuous and adaptive cancer therapies

scientific article published on 30 January 2018

Spatial vs. non-spatial eco-evolutionary dynamics in a tumor growth model.

scientific article published in September 2017

Steering Evolution with Sequential Therapy to Prevent the Emergence of Bacterial Antibiotic Resistance

scientific article

Sweat but no gain: inhibiting proliferation of multidrug resistant cancer cells with "ersatzdroges".

scientific article

Systemic Buffers Inhibit Carcinogenesis in TRAMP Mice ⬇️

scientific article published on June 15, 2012

Systems biologists seek fuller integration of systems biology approaches in new cancer research programs

scientific article

Test-retest reproducibility analysis of lung CT image features

scientific article

The 2019 mathematical oncology roadmap

scientific article published on 19 June 2019

The Critical Roles of Information and Nonequilibrium Thermodynamics in Evolution of Living Systems ⬇️

scientific article published on February 28, 2013

The Ecology of Human Papillomavirus–Induced Epithelial Lesions and the Role of Somatic Evolution in Their Progression ⬇️

scientific article published on April 18, 2013

The Goldilocks Window of Personalized Chemotherapy: Getting the Immune Response Just Right

scientific article published on 06 August 2019

The Physics of Cancer

scientific article published on 24 April 2019

The Warburg effect as an adaptation of cancer cells to rapid fluctuations in energy demand

scientific article published on 18 September 2017

The evolutionary ecology of transmissible cancers

scientific article published on 06 February 2016

The glycolytic phenotype in carcinogenesis and tumor invasion: insights through mathematical models

scientific article published in July 2003

The multiple facets of Peto's paradox: a life-history model for the evolution of cancer suppression

scientific article

The possible role of postoperative azotemia in enhanced survival of patients with metastatic renal cancer after cytoreductive nephrectomy

scientific article

The potential role of systemic buffers in reducing intratumoral extracellular pH and acid-mediated invasion

scientific article published on 10 March 2009

The role of acidity in solid tumour growth and invasion

scientific article (publication date: August 2005)

Towards Multidrug Adaptive Therapy

scientific article published on 16 January 2020

Transmissible Cancers in an Evolutionary Perspective

scientific article published on 12 June 2020

Transmissible cancers, are they more common than thought?

scientific article published on 17 May 2016

Tris-base buffer: a promising new inhibitor for cancer progression and metastasis.

scientific article published on 29 May 2017

Tumor Evolution in Space: The Effects of Competition Colonization Tradeoffs on Tumor Invasion Dynamics ⬇️

scientific article published on March 6, 2013

Tumour–stromal interactions in acid-mediated invasion: A mathematical model ⬇️

scientific article published on September 8, 2010

Turnover modulates the need for a cost of resistance in adaptive therapy

scientific article published on 10 November 2020

Variance of SUVs for FDG-PET/CT is greater in clinical practice than under ideal study settings

scientific article published on March 2013

Vascular measurements correlate with estrogen receptor status

scientific article

Why do cancers have high aerobic glycolysis?

scientific article

pH imaging. A review of pH measurement methods and applications in cancers.

scientific article

Paulina is supported by:

About Paulina

Help