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List of works by Yoshinobu Takakura

Accelerated growth of B16BL6 tumor in mice through efficient uptake of their own exosomes by B16BL6 cells.

scientific article published on July 2017

Amelioration of Experimental Autoimmune Encephalomyelitis in Mice by Interferon-Beta Gene Therapy, Using a Long-Term Expression Plasmid Vector

scientific article published on 3 March 2017

Cell type-specific and common characteristics of exosomes derived from mouse cell lines: Yield, physicochemical properties, and pharmacokinetics.

scientific article published on 5 October 2016

Effects of Localization of Antigen Proteins in Antigen-Loaded Exosomes on Efficiency of Antigen Presentation

scientific article published on 13 May 2019

Enhanced Class I Tumor Antigen Presentation via Cytosolic Delivery of Exosomal Cargos by Tumor-Cell-Derived Exosomes Displaying a pH-Sensitive Fusogenic Peptide.

scientific article published on 4 October 2017

Exosome-based tumor antigens-adjuvant co-delivery utilizing genetically engineered tumor cell-derived exosomes with immunostimulatory CpG DNA.

scientific article

Macrophage-dependent clearance of systemically administered B16BL6-derived exosomes from the blood circulation in mice

scientific article published on 9 February 2015

Multifunctionalization of Cells with a Self-Assembling Molecule to Enhance Cell Engraftment

scientific article published on 05 April 2019

Pharmacokinetics of Exosomes-An Important Factor for Elucidating the Biological Roles of Exosomes and for the Development of Exosome-Based Therapeutics.

scientific article published on 7 March 2017

Quantitative analysis of tissue distribution of the B16BL6-derived exosomes using a streptavidin-lactadherin fusion protein and iodine-125-labeled biotin derivative after intravenous injection in mice.

scientific article

Role of Phosphatidylserine-Derived Negative Surface Charges in the Recognition and Uptake of Intravenously Injected B16BL6-Derived Exosomes by Macrophages.

scientific article published on 17 September 2016

Role of extracellular vesicle surface proteins in the pharmacokinetics of extracellular vesicles

scientific article published on 30 January 2018