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List of works by John S Blanchard

Aminoglycoside 2'-N-acetyltransferase from Mycobacterium tuberculosis in complex with coenzyme A and aminoglycoside substrates

scientific article

Bacterial Branched-Chain Amino Acid Biosynthesis: Structures, Mechanisms, and Drugability.

scientific article published on 4 October 2017

Bacterial GCN5-Related N-Acetyltransferases: From Resistance to Regulation

scientific article

Biochemical Characterization of the Mycobacterium smegmatis Threonine Deaminase

scientific article published on 03 October 2018

Biochemical and Structural Characterization of Mycobacterium tuberculosis β-Lactamase with the Carbapenems Ertapenem and Doripenem

scientific article

Can Inhibitor-Resistant Substitutions in the Mycobacterium tuberculosis  -Lactamase BlaC Lead to Clavulanate Resistance?: a Biochemical Rationale for the Use of  -Lactam- -Lactamase Inhibitor Combinations

scientific article

Crystal structure of RimI fromSalmonella typhimurium LT2, the GNAT responsible for Nα-acetylation of ribosomal protein S18

scientific article

Crystal structure of mycothiol synthase (Rv0819) fromMycobacterium tuberculosisshows structural homology to the GNAT family of N-acetyltransferases

scientific article

Crystallization of a pentapeptide-repeat protein by reductive cyclic pentylation of free amines with glutaraldehyde

scientific article

Functional characterization of a novel ArgA from Mycobacterium tuberculosis

scientific article

Kinetic and Structural Analysis of Bisubstrate Inhibition of the Salmonella enterica Aminoglycoside 6‘- N -Acetyltransferase † , ‡

scientific article

Kinetic and chemical mechanism of alpha-isopropylmalate synthase from Mycobacterium tuberculosis

scientific article

Mechanism-Based Inhibition of the Mycobacterium tuberculosis Branched-Chain Aminotransferase by d- and l-Cycloserine.

scientific article

Mechanistic Characterization of Escherichia coli l-Aspartate Oxidase from Kinetic Isotope Effects

scientific article published on 12 July 2017

Mechanistic and Structural Analysis of Aminoglycoside N -Acetyltransferase AAC(6′)-Ib and Its Bifunctional, Fluoroquinolone-Active AAC(6′)-Ib-cr Variant † ‡

scientific article

Mechanistic and Structural Analysis of Human Spermidine/Spermine N 1 -Acetyltransferase † , ‡

scientific article

Meropenem-Clavulanate Is Effective Against Extensively Drug-Resistant Mycobacterium tuberculosis

scientific article

NXL104 Irreversibly Inhibits the β-Lactamase from Mycobacterium tuberculosis

scientific article

New Insight into the Mechanism of Action of and Resistance to Isoniazid:  Interaction of Mycobacterium tuberculosis enoyl-ACP Reductase with INH-NADP

scientific article

Pentapeptide repeat proteins

scientific article

Pentapeptide-repeat proteins that act as topoisomerase poison resistance factors have a common dimer interface

scientific article

Rv0802c fromMycobacterium tuberculosis: the first structure of a succinyltransferase with the GNAT fold

scientific article

Structural and enzymatic analysis of MshA from Corynebacterium glutamicum: substrate-assisted catalysis

scientific article

Structural characterization of the fusion of two pentapeptide repeat proteins, Np275 and Np276, from Nostoc punctiforme: resurrection of an ancestral protein

scientific article

Structural, kinetic and chemical mechanism of isocitrate dehydrogenase-1 from Mycobacterium tuberculosis

scientific article

Structure and functions of the GNAT superfamily of acetyltransferases

scientific article

Structure of QnrB1, a Plasmid-mediated Fluoroquinolone Resistance Factor ⬇️

scientific article published on May 19, 2011

Structure of the covalent adduct formed between Mycobacterium tuberculosis beta-lactamase and clavulanate

scientific article

Structures of the Michaelis Complex (1.2 Å) and the Covalent Acyl Intermediate (2.0 Å) of Cefamandole Bound in the Active Sites of the Mycobacterium tuberculosis β-Lactamase K73A and E166A Mutants, ⬇️

scientific article published on October 25, 2010

Tebipenem, a New Carbapenem Antibiotic, Is a Slow Substrate That Inhibits the β-Lactamase from Mycobacterium tuberculosis

scientific article

The metabolism of nitrosothiols in the Mycobacteria: identification and characterization of S-nitrosomycothiol reductase

scientific article

The structure and mechanism of the Mycobacterium tuberculosis cyclodityrosine synthetase ⬇️

scientific article published on September 19, 2010

The three-dimensional structures of the Mycobacterium tuberculosis dihydrodipicolinate reductase-NADH-2,6-PDC and -NADPH-2,6-PDC complexes. Structural and mutagenic analysis of relaxed nucleotide specificity

scientific article

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