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List of works by Michael T Lotze

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

scientific article (publication date: November 2016)

5-Fluorouracil upregulates cell surface B7-H1 (PD-L1) expression in gastrointestinal cancers

scientific article published on 18 October 2016

A Janus Tale of Two Active High Mobility Group Box 1 (HMGB1) Redox States

scientific article published on December 20, 2012

A Randomized Phase II Preoperative Study of Autophagy Inhibition With High-Dose Hydroxychloroquine and Gemcitabine/Nab-Paclitaxel in Pancreatic Cancer Patients

scientific article published on 10 March 2020

A basis for distinguishing cultured dendritic cells and macrophages in cytospins and fixed sections

scientific article published on 01 January 2005

A decade in the life of tumor immunology

scientific article published on 01 March 2001

A large scale method of separating multiple lymphokines secreted by the murine EL-4 thymoma

scientific article published on 01 January 1985

A new approach to the therapy of cancer based on the systemic administration of autologous lymphokine-activated killer cells and recombinant interleukin-2

scientific article published on 01 August 1986

A peaceful death orchestrates immune balance in a chaotic environment

scientific article published on 25 October 2019

A phase I trial of a synthetic mucin peptide vaccine. Induction of specific immune reactivity in patients with adenocarcinoma

scientific article published on 01 June 1996

A pilot study of the combination of interleukin-2-based immunotherapy and radiation therapy

scientific article published on 01 November 1992

A progress report on the treatment of 157 patients with advanced cancer using lymphokine-activated killer cells and interleukin-2 or high-dose interleukin-2 alone

scientific article published on 01 April 1987

A prospective randomized trial evaluating colloid versus crystalloid resuscitation in the treatment of the vascular leak syndrome associated with interleukin-2 therapy

scientific article published on 01 January 1994

AGER/RAGE-mediated autophagy promotes pancreatic tumorigenesis and bioenergetics through the IL6-pSTAT3 pathway

scientific article published on June 1, 2012

AMPK-Mediated BECN1 Phosphorylation Promotes Ferroptosis by Directly Blocking System Xc- Activity

scientific article published on 26 July 2018

Actin-binding protein Profilin1 promotes aggressiveness of clear cell renal cell carcinoma cells

scientific article published on 03 September 2020

Activation of Dendritic Cells by Surrogate T Cell Interactions Leads to Enhanced Costimulation, Secretion of TH1-Associated Cytokines, and CTL Inductive Capacity

scientific article published on 01 January 1997

Active specific T-cell-based immunotherapy for cancer: nucleic acids, peptides, whole native proteins, recombinant viruses, with dendritic cell adjuvants or whole tumor cell-based vaccines. Principles and future prospects

scientific article published on March 1, 1998

Addicted to death: invasive cancer and the immune response to unscheduled cell death

scientific article

Addition of interleukin 12 to low dose interleukin 2 treatment improves antitumor efficacy in vivo.

scientific article

Administration of systemic or local interleukin-2 enhances the anti-tumor effects of interleukin-12 gene therapy

scientific article published on February 1995

Adoptive transfer of natural killer cells promotes the anti-tumor efficacy of T cells

scientific article published on July 2016

Amino acid substitutions at position 97 in HLA-A2 segregate cytolysis from cytokine release in MART-1/Melan-A peptide AAGIGILTV-specific cytotoxic T lymphocytes

scientific article published on 01 November 1996

Antitumor Activities of IL-12 and Mechanisms of Action

scientific article published on January 1, 1997

Antitumor effects of interleukin-12 (IL-12): applications for the immunotherapy and gene therapy of cancer.

scientific article

Apoptosis induced in T cells by human neuroblastoma cells: role of Fas ligand

scientific article published on 01 January 1998

Apoptosis promotes early tumorigenesis

scientific article published on December 13, 2010

Assessment of Response to Neoadjuvant Therapy Using CT Texture Analysis in Patients With Resectable and Borderline Resectable Pancreatic Ductal Adenocarcinoma

scientific article published on 04 December 2019

Autologous human dendriphages pulsed with synthetic or natural tumor peptides elicit tumor-specific CTLs in vitro.

scientific article published on March 1998

Autologous human monocyte-derived dendritic cells genetically modified to express melanoma antigens elicit primary cytotoxic T cell responses in vitro: enhancement by cotransfection of genes encoding the Th1-biasing cytokines IL-12 and IFN-alpha

scientific article published on February 1, 1998

Autophagy inhibition in combination cancer treatment.

scientific article published on December 2009

Autophagy inhibition is the next step in the treatment of glioblastoma patients following the Stupp era

scientific article published on 05 August 2020

Autophagy is required for IL-2-mediated fibroblast growth

scientific article published on November 27, 2012

Autophagy promotes ferroptosis by degradation of ferritin

scientific article published on 31 May 2016

Bi- and Tri-Specific T Cell Engager-Armed Oncolytic Viruses: Next-Generation Cancer Immunotherapy

scientific article published on 10 July 2020

Blocking the interleukin 2 (IL2)-induced systemic autophagic syndrome promotes profound antitumor effects and limits toxicity.

scientific article

Bone marrow-derived dendritic cells pulsed with a tumor-specific peptide elicit effective anti-tumor immunity against intracranial neoplasms

scientific article published on October 5, 1998

Bone marrow-derived dendritic cells serve as potent adjuvants for peptide-based antitumor vaccines

scientific article published on January 1997

C16 ceramide accumulates following androgen ablation in LNCaP prostate cancer cells

scientific article published in September 2003

CC chemokine receptor-7 on dendritic cells is induced after interaction with apoptotic tumor cells: critical role in migration from the tumor site to draining lymph nodes

scientific article published on 01 April 2000

CD154 inhibits tumor-induced apoptosis in dendritic cells and tumor growth

scientific article published on 01 July 1999

CDK1/2/5 inhibition overcomes IFNG-mediated adaptive immune resistance in pancreatic cancer

scientific article published on 14 August 2020

Cancer and inflammation: promise for biologic therapy.

scientific article

Cancer genomics: the unknown unknowns.

scientific article

Cancer immunotherapy of established tumors with IL-12. Effective delivery by genetically engineered fibroblasts

scientific article published on 01 August 1995

Cancer immunotherapy using interleukin-2 and interleukin-2-activated lymphocytes

scientific article

Cell death and DAMPs in acute pancreatitis

scientific article

Cell-mediated autophagy promotes cancer cell survival.

scientific article

Cells invading tumors: strategies for the identification and expansion of tumor reactive lymphocytes

scientific article published on April 1, 1988

Ceramide mediates tumor-induced dendritic cell apoptosis

scientific article published in October 2001

Characteristics of Malignant Pleural Effusion Resident CD8+ T Cells from a Heterogeneous Collection of Tumors

scientific article published on 27 August 2020

Characterization and transduction of a retroviral vector encoding human interleukin-4 and herpes simplex virus-thymidine kinase for glioma tumor vaccine therapy

scientific article

Chloroquine reduces hypercoagulability in pancreatic cancer through inhibition of neutrophil extracellular traps.

scientific article

Cisplatin prevents high mobility group box 1 release and is protective in a murine model of hepatic ischemia/reperfusion injury

scientific article published on 01 August 2009

Classification of current anticancer immunotherapies

scientific article

Clearance kinetics and matrix binding partners of the receptor for advanced glycation end products.

scientific article

Clinical effects and toxicity of interleukin-2 in patients with cancer

scientific article

Clinical trial to assess the safety, feasibility, and efficacy of transferring a potentially anti-arthritic cytokine gene to human joints with rheumatoid arthritis

scientific article published on 01 June 1996

Clockophagy is a novel selective autophagy process favoring ferroptosis

scientific article published on 24 July 2019

Combined treatment with interleukin-18 and low-dose interleukin-2 induced regression of a murine sarcoma and memory response

scientific article published in May 2003

Complementary dendritic cell-activating function of CD8+ and CD4+ T cells: helper role of CD8+ T cells in the development of T helper type 1 responses.

scientific article

Consensus guidelines for the definition, detection and interpretation of immunogenic cell death

scientific article published on 01 March 2020

Consensus nomenclature for CD8(+) T cell phenotypes in cancer

scientific article published on 25 February 2015

Construction and characterization of retroviral vectors expressing biologically active human interleukin-12.

scientific article published in December 1994

Correction to: Toward a comprehensive view of cancer immune responsiveness: a synopsis from the SITC workshop

scientific article published on 04 July 2019

Correction: Damage Associated Molecular Pattern Molecule-Induced microRNAs (DAMPmiRs) in Human Peripheral Blood Mononuclear Cells.

scientific article published on 21 August 2012

Corrigendum: Longitudinal Analysis of T and B Cell Receptor Repertoire Transcripts Reveal Dynamic Immune Response in COVID-19 Patients

scientific article published on 21 December 2020

Cutting edge: high-mobility group box 1 preconditioning protects against liver ischemia-reperfusion injury

scientific article published on 01 June 2006

Cytokine gene therapy of cancer using interleukin-12: murine and clinical trials.

scientific article published on October 1996

Cytokine gene therapy of gliomas: effective induction of therapeutic immunity to intracranial tumors by peripheral immunization with interleukin-4 transduced glioma cells

scientific article

Cytokine gene therapy of gliomas: induction of reactive CD4+ T cells by interleukin-4-transfected 9L gliosarcoma is essential for protective immunity

scientific article published in May 2000

Cytokine regulation of tumor necrosis factor-alpha and -beta (lymphotoxin)-messenger RNA expression in human peripheral blood mononuclear cells

scientific article published on 01 August 1990

Cytokine-mediated protection of human dendritic cells from prostate cancer-induced apoptosis is regulated by the Bcl-2 family of proteins

scientific article published on August 2000

Cytokines alter target cell susceptibility to lysis. II. Evaluation of tumor infiltrating lymphocytes

scientific article published on 01 March 1989

Cytokines alter target cell susceptibility to lysis: I. Evaluation of non-major histocompatibility complex-restricted effectors reveals differential effects on natural and lymphokine-activated killing

scientific article published in April 1990

Cytolytic T-cell clones define HLA-A2-restricted human cutaneous melanoma peptide epitopes: correlation with T-cell receptor usage

scientific article

Cytolytic cells induce HMGB1 release from melanoma cell lines

scientific article published on 12 September 2006

Cytosolic HMGB1 controls the cellular autophagy/apoptosis checkpoint during inflammation.

scientific article

DAMPs and autophagy: cellular adaptation to injury and unscheduled cell death

scientific article published on 06 February 2013

DAMPs, ageing, and cancer: The 'DAMP Hypothesis'.

scientific article published on 30 October 2014

DNA released from neutrophil extracellular traps (NETs) activates pancreatic stellate cells and enhances pancreatic tumor growth

scientific article published on 11 June 2019

DNA vaccines targeting dendritic cells for the immunotherapy of cancer

scientific article published on 01 January 1998

Damage associated molecular pattern molecule-induced microRNAs (DAMPmiRs) in human peripheral blood mononuclear cells

scientific article

Damage associated molecular pattern molecules

scientific article

Defining best practices for tissue procurement in immuno-oncology clinical trials: consensus statement from the Society for Immunotherapy of Cancer Surgery Committee

scientific article published on 01 November 2020

Defining the critical hurdles in cancer immunotherapy

scientific article published on 14 December 2011

Delayed reactions to contrast media after interleukin-2 immunotherapy

scientific article published on April 1, 1992

Dendritic Cell Based Therapy of Cancer

scientific article published on January 1, 1997

Dendritic cell/peptide cancer vaccines: clinical responsiveness and epitope spreading

scientific article published on 01 May 2000

Dendritic cells prolong tumor-specific T-cell survival and effector function after interaction with tumor targets

scientific article published on 01 March 2001

Dendritic cells promote T-cell survival or death depending upon their maturation state and presentation of antigen

scientific article published on 01 May 2000

Dendritic cells pulsed with apoptotic squamous cell carcinoma have anti-tumor effects when combined with interleukin-2

scientific article published on 01 August 2001

Depletion of high mobility group box 1(HMGB1) in dendritic cells (DCs) suppresses tumorigenesis and promotes viral clearance

scientific article published on 6 November 2014

Detection of naturally processed and HLA-A1-presented melanoma T-cell epitopes defined by CD8(+) T-cells' release of granulocyte-macrophage colony-stimulating factor but not by cytolysis

scientific article

Development of Dendritic Cell-Based Genetic Vaccines for Cancer

scientific article published on January 1, 1997

Development of long-term cell lines and lymphoid clones reactive against murine and human tumors: a new approach to the adoptive immunotherapy of cancer

scientific article published on 01 August 1982

Dicer-regulated microRNAs 222 and 339 promote resistance of cancer cells to cytotoxic T-lymphocytes by down-regulation of ICAM-1.

scholarly article

Different measures of HMGB1 location in cancer immunology

scientific article published on 29 October 2019

Differential antitumor effects of administration of recombinant IL-18 or recombinant IL-12 are mediated primarily by Fas-Fas ligand- and perforin-induced tumor apoptosis, respectively

scientific article published on 01 July 1999

Differential effects of IL-12 on the generation of alloreactive CTL mediated by murine and human dendritic cells: a critical role for nitric oxide

scientific article published on May 1, 2003

Differential regulation of epidermal and dermal dendritic cells by IL-12 and Flt3 ligand

scientific article published on 01 December 1999

Direct molecular interactions between HMGB1 and TP53 in colorectal cancer

scientific article published on May 1, 2012

Effect of vascular endothelial growth factor and FLT3 ligand on dendritic cell generation in vivo

scientific article published on 01 September 1999

Effective cytokine gene therapy against an intracranial glioma using a retrovirally transduced IL-4 plus HSVtk tumor vaccine

scientific article published in February 1999

Effective eradication of established murine tumors with IL-12 gene therapy using a polycistronic retroviral vector.

scientific article

Efficacy of adoptive therapy with tumor-infiltrating lymphocytes and recombinant interleukin-2 in advanced cutaneous melanoma: a systematic review and meta-analysis

scientific article published on 01 December 2019

Efficacy of adoptive transfer of expanded fetal liver-derived precursor syngeneic and allogeneic murine NK cells against solid tumors

scientific article published on 4 November 2015

Emerging concepts in biomarker discovery; the US-Japan Workshop on Immunological Molecular Markers in Oncology

scientific article

Endogenous HMGB1 regulates autophagy

scientific article

Endothelial activation during interleukin 2 immunotherapy. A possible mechanism for the vascular leak syndrome

scientific article published on 01 March 1988

Enhanced Neutrophil Extracellular Trap Formation in Acute Pancreatitis Contributes to Disease Severity and Is Reduced by Chloroquine

scientific article published on 24 January 2019

Enhancement of anti-tumor immunity by injection of fibroblasts genetically engineered to produce IL-12 and to express CD70.

scientific article published on January 1998

Enhancement of antitumor immunity by expression of CD70 (CD27 ligand) or CD154 (CD40 ligand) costimulatory molecules in tumor cells

scientific article published on May 1, 1998

Ethyl pyruvate administration inhibits hepatic tumor growth

scientific article

Ethyl pyruvate decreases HMGB1 release and ameliorates murine colitis

scientific article published on 19 May 2009

Expansion of tumor-infiltrating lymphocytes from human tumors using the T-cell growth factors interleukin-2 and interleukin-4

scientific article published on 01 November 1993

Extracellular DNA promotes colorectal tumor cell survival after cytotoxic chemotherapy

scientific article published on 28 March 2018

FLT3 ligand administration inhibits tumor growth in murine melanoma and lymphoma

scientific article published on 01 February 1998

FLT3 ligand induces the generation of functionally active dendritic cells in mice

scientific article published on 01 August 1997

FLT3-ligand administration inhibits liver metastases: role of NK cells

scientific article published on 01 December 1998

FLT3: receptor and ligand. Biology and potential clinical application

scientific article published on 01 March 1998

Feature Selection for Classification of SELDI-TOF-MS Proteomic Profiles

scientific article published in January 2005

Fibroblasts genetically engineered to secrete interleukin 12 can suppress tumor growth and induce antitumor immunity to a murine melanoma in vivo.

scientific article published on January 1994

Flow-cytometric determination of peptide-class I complex formation. Identification of p53 peptides that bind to HLA-A2.

scientific article published on February 1994

Focus on FOCIS: interleukin 2 treatment associated autoimmunity.

scientific article published on May 2008

Gene therapy of cancer: a pilot study of IL-4-gene-modified fibroblasts admixed with autologous tumor to elicit an immune response

scientific article published in January 1994

Gene therapy of malignant gliomas: a phase I study of IL-4-HSV-TK gene-modified autologous tumor to elicit an immune response

scientific article published in March 2000

Gene transfer into humans--immunotherapy of patients with advanced melanoma, using tumor-infiltrating lymphocytes modified by retroviral gene transduction

scientific article

Gene-based strategies for the immunotherapy of cancer

scientific article published on July 1, 1997

Generation of anti-p53 cytotoxic T lymphocytes from human peripheral blood using autologous dendritic cells

scientific article published on June 1999

Genetically marking human cells--results of the first clinical gene transfer studies.

scientific article published on June 1995

Genetically modified bone marrow‐derived dendritic cells expressing tumor‐associated viral or “self” antigens induce antitumor immunity in vivo

scientific article published on October 1, 1997

Growth stimulation of human head and neck squamous cell carcinoma cell lines by interleukin 4.

scientific article published in January 1996

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Gutting it Out: Developing Effective Immunotherapies for Patients With Colorectal Cancer

scientific article published on 06 January 2021

HIV-1-specific CTL responses primed in vitro by blood-derived dendritic cells and Th1-biasing cytokines

scientific article published on 01 March 1999

HLA association with response and toxicity in melanoma patients treated with interleukin 2-based immunotherapy

scientific article

HMGB1 Controls Liver Cancer Initiation through YAP-dependent Aerobic Glycolysis.

scientific article published on 17 November 2017

HMGB1 Promotes Myeloid Egress and Limits Lymphatic Clearance of Malignant Pleural Effusions

scientific article published on 04 September 2020

HMGB1 as a potential biomarker and therapeutic target for severe COVID-19

scientific article published on 07 December 2020

HMGB1 as an autophagy sensor in oxidative stress

scientific article published on 01 August 2011

HMGB1 in cancer: good, bad, or both?

scientific article published on 30 May 2013

HMGB1 in health and disease

scientific article

HMGB1 release and redox regulates autophagy and apoptosis in cancer cells

scientific article

HMGB1-induced autophagy promotes chemotherapy resistance in leukemia cells

scientific article published on October 7, 2010

HMGB1: The Central Cytokine for All Lymphoid Cells

scientific article published on March 20, 2013

HSPA5 Regulates Ferroptotic Cell Death in Cancer Cells

scientific article published on 27 January 2017

Helper Activity of Natural Killer Cells During the Dendritic Cell-mediated Induction of Melanoma-specific Cytotoxic T Cells

scientific article published on April 1, 2011

Hepatic ischemia/reperfusion injury involves functional TLR4 signaling in nonparenchymal cells.

scientific article

High Mobility Group Box 1 (HMGB1) Activates an Autophagic Response to Oxidative Stress

scientific article published on June 6, 2011

High mobility group B1 protein suppresses the human plasmacytoid dendritic cell response to TLR9 agonists.

scientific article published in December 2006

High mobility group box 1 (HMGB1) phenotypic role revealed with stress

scientific article

High mobility group box I (HMGB1) release from tumor cells after treatment: implications for development of targeted chemoimmunotherapy

scientific article published on September 2007

High-Mobility Group Box 1 Is Essential for Mitochondrial Quality Control

scientific article published on June 8, 2011

High-Mobility Group Box 1 Promotes Hepatocellular Carcinoma Progression through miR-21-Mediated Matrix Metalloproteinase Activity

scientific article

High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: analysis of 270 patients treated between 1985 and 1993

scientific article (publication date: July 1999)

High-mobility group box 1 activates caspase-1 and promotes hepatocellular carcinoma invasiveness and metastases

scientific article published on June 1, 2012

High-mobility group box 1 and cancer

scientific article

High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal

scientific article (publication date: April 2005)

High-mobility group box 1, oxidative stress, and disease

scientific article published on April 2011

Host immune response in renal cell cancer: Interleukin-4 (IL-4) and IL-10 mRNA are frequently detected in freshly collected tumor-infiltrating lymphocytes

article

Human gene marker/therapy clinical protocols

scientific article published on 01 August 1996

Human gene marker/therapy clinical protocols

scientific article published on 01 December 1996

Human gene marker/therapy clinical protocols

scientific article published on 01 December 1999

Human gene marker/therapy clinical protocols

scientific article published on 01 April 2000

Human gene marker/therapy clinical protocols

scientific article published on 01 December 1997

Human gene transfer: characterization of human tumor-infiltrating lymphocytes as vehicles for retroviral-mediated gene transfer in man

scientific article published on January 1990

Human intestinal V delta 1+ T cells obtained from patients with colon cancer respond exclusively to SEB but not to SEA.

scientific article published on April 1995

Human intestinal Vdelta1+ lymphocytes recognize tumor cells of epithelial origin

scientific article

Human lymphokine-activated killer cell activity. Role of IL-2, IL-4, and IL-7

scientific article published on 01 December 1991

Human lymphokine-activated killer cells: further isolation and characterization of the precursor and effector cell

scientific article

Hypoxia induced HMGB1 and mitochondrial DNA interactions mediate tumor growth in hepatocellular carcinoma through Toll-like receptor 9

scientific article published on 12 February 2015

IB-03IDH MUTANT GLIOMAS ARE RESISTANT TO NATURAL KILLER CELL-MEDIATED CYTOLYSIS.

scientific article

IDH mutant gliomas escape natural killer cell immune surveillance by downregulation of NKG2D ligand expression

scientific article published on 25 April 2016

IFN-alpha-expressing tumor cells enhance generation and promote survival of tumor-specific CTLs

scientific article

IFN-gamma-inducing factor/IL-18 administration mediates IFN-gamma- and IL-12-independent antitumor effects

scientific article published on February 15, 1998

IL-12 gene therapy using direct injection of tumors with genetically engineered autologous fibroblasts

scientific article published in December 1995

IL-12-engineered dendritic cells serve as effective tumor vaccine adjuvants in vivo

scientific article published on 01 October 1996

IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis

scientific article published on November 2005

IL-2-based immunotherapy alters circulating neutrophil Fc receptor expression and chemotaxis

scientific article published on 01 May 1990

IL-4 regulates IL-2 induction of lymphokine-activated killer activity from human lymphocytes

scientific article published on May 1989

IL-6/IFN-beta-2 as a circulating hormone. Induction by cytokine administration in humans

scientific article published on 01 March 1989

IMPS-45IDH MUTANT GLIOMAS ESCAPE NATURAL KILLER CELL IMMUNE SURVEILLANCE THROUGH DOWNREGULATION OF NKG2D LIGANDS.

scientific article

Identification of Meth A sarcoma-derived class I major histocompatibility complex-associated peptides recognized by a specific CD8+ cytotoxic T lymphocyte.

scientific article published on January 1995

Identification of T-cell epitopes: rapid isolation of class I-presented peptides from viable cells by mild acid elution.

scientific article published on August 1993

Identification of baicalein as a ferroptosis inhibitor by natural product library screening

scientific article

Identification of human melanoma peptides recognized by class I restricted tumor infiltrating T lymphocytes

scientific article published on 01 October 1993

Identification of wild-type and mutant p53 peptides binding to HLA-A2 assessed by a peptide loading-deficient cell line assay and a novel major histocompatibility complex class I peptide binding assay

scientific article published on March 1994

Imaging analysis of STAT1 and NF-kappaB translocation in dendritic cells at the single cell level

scientific article published on 05 October 2004

Imaging analysis of STAT1 and NF-kappaB translocation in dendritic cells at the single cell level

scientific article published in January 2005

Immunohistochemical correlates of response to recombinant interleukin-2-based immunotherapy in humans

scientific article published on 01 December 1989

Immunological effects of interleukin 12 administered by bolus intravenous injection to patients with cancer

scientific article published on 01 January 1999

Importance of C16 ceramide accumulation during apoptosis in prostate cancer cells

scientific article published on February 2006

In Situ Interleukin-4 Gene Expression in Cancer Patients Treated with Genetically Modified Tumor Vaccine

scientific article published on May 1, 1995

In vitro growth of cytotoxic human lymphocytes. II. Use of T cell growth factor (TCGF) to clone human T cells

scientific article published on 01 June 1980

In vitro growth of cytotoxic human lymphocytes. III. The preparation of lectin-free T cell growth factor (TCGF) and an analysis of its activity

scientific article published on 01 June 1981

In vivo administration of purified Jurkat-derived interleukin 2 in mice

scientific article

In vivo administration of purified human interleukin 2. I. Half-life and immunologic effects of the Jurkat cell line-derived interleukin 2.

scientific article published on January 1985

In vivo administration of purified human interleukin 2. II. Half life, immunologic effects, and expansion of peripheral lymphoid cells in vivo with recombinant IL 2.

scientific article published on October 1985

In vivo administration of purified human interleukin-2 to patients with cancer: development of interleukin-2 receptor positive cells and circulating soluble interleukin-2 receptors following interleukin-2 administration

scientific article published on 01 April 1987

In vivo expansion of two distinct dendritic cells in mouse livers and its impact on liver immune regulation

scientific article published on 01 December 2006

In vivo induction of IL-6 by administration of exogenous cytokines and detection of de novo serum levels of IL-6 in tumor-bearing mice

scientific article published on 01 July 1989

Increasing numbers of hepatic dendritic cells promote HMGB1-mediated ischemia-reperfusion injury

scientific article published on 24 October 2006

Induction of antitumor immunity by direct intratumoral injection of a recombinant adenovirus vector expressing interleukin-12.

scientific article published in January 1999

Induction of systemic and therapeutic antitumor immunity using intratumoral injection of dendritic cells genetically modified to express interleukin 12

scientific article published on 01 August 1999

Induction of tumor antigen-specific immunity using plasmid DNA immunization in mice

scientific article published on 01 January 1999

Inhibiting Autophagy in Renal Cell Cancer and the Associated Tumor Endothelium

scientific article published on 01 May 2019

Inhibiting autophagy: a novel approach for the treatment of renal cell carcinoma

scientific article published on July 2013

Inhibiting systemic autophagy during interleukin 2 immunotherapy promotes long-term tumor regression.

scientific article

Inhibition of Aurora Kinase A Induces Necroptosis in Pancreatic Carcinoma

scientific article

Innate immunity mediated by the cytokine IL-1 homologue 4 (IL-1H4/IL-1F7) induces IL-12-dependent adaptive and profound antitumor immunity

scientific article (publication date: 2003)

Inside, outside, upside down: damage-associated molecular-pattern molecules (DAMPs) and redox

scientific article

Insights from immuno-oncology: the Society for Immunotherapy of Cancer Statement on access to IL-6-targeting therapies for COVID-19

scientific article published on 01 April 2020

Interferon-alpha gene therapy in combination with CD80 transduction reduces tumorigenicity and growth of established tumor in poorly immunogenic tumor models

scientific article

Interferon-α gene therapy for cancer: retroviral transduction of fibroblasts and particle-mediated transfection of tumor cells are both effective strategies for gene delivery in murine tumor models

scientific article published on October 1, 1997

Interleukin 12 gene therapy of cancer by peritumoral injection of transduced autologous fibroblasts: outcome of a phase I study

scientific article

Interleukin 2 and psoriasis

scientific article published on 01 December 1988

Interleukin 2 promotes conjugate formation by purified LAK precursors and T lymphocytes: evaluation of conjugates using flow cytometric techniques

scientific article published on 01 June 1988

Interleukin 4 promotes the growth of tumor-infiltrating lymphocytes cytotoxic for human autologous melanoma

scientific article

Interleukin-1 receptor antagonist is not detrimental to human islet cell insulin secretion but decreases insulin content

scientific article published on 01 April 1994

Interleukin-10 promotes the maintenance of antitumor CD8(+) T-cell effector function in situ

scientific article

Interleukin-12 and B7.1 co-stimulation cooperate in the induction of effective antitumor immunity and therapy of established tumors.

scientific article published in June 1996

Interleukin-12 and Flt3 ligand differentially promote dendropoiesis in vivo

scientific article published on 01 September 2000

Interleukin-12 promotes the proliferation and cytolytic maturation of immune effectors: implications for the immunotherapy of cancer

scientific article published on 01 August 1993

Interleukin-12 transduced dendritic cells induce regression of established murine neuroblastoma

scientific article

Interleukin-12: biological properties and clinical application

scientific article published on August 2007

Interleukin-17 augments tumor necrosis factor-alpha-induced elaboration of proangiogenic factors from fibroblasts

scientific article

Interleukin-17 enhances bFGF-, HGF- and VEGF-induced growth of vascular endothelial cells

scientific article

Interleukin-17 promotes angiogenesis and tumor growth

scientific article published on 31 October 2002

Interleukin-18 (IL-18) synergizes with IL-2 to enhance cytotoxicity, interferon-gamma production, and expansion of natural killer cells

scientific article published on 01 February 2001

Interleukin-18 as a novel, distinct, and distant member of the interleukin-1 family promoting development of the adaptive immune response: the interleukin-18 issue of the Journal of Immunotherapy

scientific article published on 01 March 2002

Interleukin-1F7B (IL-1H4/IL-1F7) is processed by caspase-1 and mature IL-1F7B binds to the IL-18 receptor but does not induce IFN-gamma production

scientific article (publication date: 21 April 2002)

Interleukin-2: developing additional cytokine gene therapies using fibroblasts or dendritic cells to enhance tumor immunity

scientific article

Interleukin-3 induces proliferation but not lymphokine activated killer activity from human and murine mononuclear cells

scientific article published on 01 May 1990

Interleukin-7 (IL-7) Knockout Mice. Implications for Lymphopoiesis and Organ-Specific Immunity

scientific article published on January 1, 1998

Interleukin-7 (IL-7) in colorectal cancer: IL-7 is produced by tissues from colorectal cancer and promotes preferential expansion of tumour infiltrating lymphocytes

scientific article published on 01 February 1997

Interleukin‐12 Gene Therapy Prevents Establishment of SCC VII Squamous Cell Carcinomas, Inhibits Tumor Growth, and Elicits Long‐term Antitumor Immunity in Syngeneic C3H Mice

scientific article published on February 1, 1998

Intracellular HMGB1 as a novel tumor suppressor of pancreatic cancer

scientific article

Intracellular Hmgb1 inhibits inflammatory nucleosome release and limits acute pancreatitis in mice

scientific article published on 17 December 2013

Intraperitoneal administration of interleukin-2 in patients with cancer

scientific article

Intravenous administration of recombinant human macrophage colony-stimulating factor to patients with metastatic cancer: a phase I study

scientific article published on 01 October 1992

Islet cell transplantation facilitated by gene transfer

scientific article published on December 1992

Isoforms of Neuropilin-2 Denote Unique Tumor-Associated Macrophages in Breast Cancer

scientific article published on 27 April 2022

JTC801 Induces pH-dependent Death Specifically in Cancer Cells and Slows Growth of Tumors in Mice

scientific article published on 14 December 2017

Life after death: targeting high mobility group box 1 in emergent cancer therapies

scientific article published on January 18, 2013

Limb-sparing surgery for soft tissue sarcomas: wound related morbidity in patients undergoing wide local excision.

scientific article published in September 1987

Local IL-4 delivery enhances immune reactivity to murine tumors: gene therapy in combination with IL-2.

scientific article published in March 1994

Local administration of IL-12-transfected dendritic cells induces antitumor immune responses to colon adenocarcinoma in the liver in mice

scientific article published in November 2002

Longitudinal Analysis of T and B Cell Receptor Repertoire Transcripts Reveal Dynamic Immune Response in COVID-19 Patients

scientific article published on 30 September 2020

Low-dose cisplatin administration in murine cecal ligation and puncture prevents the systemic release of HMGB1 and attenuates lethality

scientific article

Lymphatics, lymph nodes and the immune system: barriers and gateways for cancer spread

scientific article published on August 2012

Lymphokine-activated killer (LAK) cell phenomenon. IV. Lysis by LAK cell clones of fresh human tumor cells from autologous and multiple allogeneic tumors

scientific article published on 01 July 1985

Lymphokine-activated killer (LAK) cells. Analysis of factors relevant to the immunotherapy of human cancer

scientific article published in March 1985

Lysis of fresh and cultured autologous tumor by human lymphocytes cultured in T-cell growth factor

scientific article published on 01 November 1981

Lysis of human solid tumors by autologous cells sensitized in vitro to alloantigens

scientific article published on 01 July 1981

Making cold malignant pleural effusions hot: driving novel immunotherapies

scientific article published on 22 January 2019

Masquerader: high mobility group box-1 and cancer

scientific article

Mass spectrometric identification of a naturally processed melanoma peptide recognized by CD8+ cytotoxic T lymphocytes

scientific article

Mass spectrometric identification of increased C16 ceramide levels during apoptosis

scientific article published on October 1999

Mechanisms of immunologic antitumor therapy: lessons from the laboratory and clinical applications

scientific article published on June 1990

Mechanistic insights into achievement of cardiac allograft long-term survival by treatment with immature dendritic cells and sub-dose sirolimus

scientific article published on 25 January 2006

Meeting report: The 13th Annual Meeting of the Translational Research Cancer Centers Consortium (TrC3); Immune Suppression and the Tumor Microenvironment, Columbus, Ohio; March 1-2, 2010.

scientific article published on September 2010

Metabolic regulation by HMGB1-mediated autophagy and mitophagy

scientific article published on 01 October 2011

Methods for generation of genetically modified fibroblasts for immunotherapy of cancer

scientific article published on 01 January 1997

MicroRNAs in immune regulation--opportunities for cancer immunotherapy

scientific article

Mitochondrial lipid alterations during Fas- and radiation-induced apoptosis

scientific article

Monocytes promote natural killer cell interferon gamma production in response to the endogenous danger signal HMGB1

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Multianalyte profiling of serum cytokines for detection of pancreatic cancer

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Murine dendritic cell-induced tumor apoptosis is partially mediated by nitric oxide

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Murine dendritic cells express functional delta-type opioid receptors

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Murine models of cancer cytokine gene therapy using interleukin-12.

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Ménage à Trois in stress: DAMPs, redox and autophagy

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NIH conference. New approaches to the immunotherapy of cancer using interleukin-2.

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NK cell HMGB1 mediates IL-2-induced “systemic autophagic” toxicity

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Natural killer, but not natural killer T, cells play a necessary role in the promotion of an innate antitumor response induced by IL-18

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Natural killer-dendritic cell cross-talk in cancer immunotherapy

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Neuroblastoma-derived gangliosides inhibit dendritic cell generation and function

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New treatment options for patients with melanoma: review of melanoma-derived T-cell epitope-based peptide vaccines.

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Not just nuclear proteins: 'novel' autophagy cancer treatment targets - p53 and HMGB1

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Novel chemokine-like activities of histones in tumor metastasis

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Nuclear DAMP complex-mediated RAGE-dependent macrophage cell death

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Observations on the systemic administration of autologous lymphokine-activated killer cells and recombinant interleukin-2 to patients with metastatic cancer

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Oncolytic virus promotes tumor-reactive infiltrating lymphocytes for adoptive cell therapy

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Outcomes of Neoadjuvant Chemotherapy Versus Chemoradiation in Localized Pancreatic Cancer: A Case-Control Matched Analysis

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PAMPs and DAMPs: signal 0s that spur autophagy and immunity

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PINK1 and PARK2 Suppress Pancreatic Tumorigenesis through Control of Mitochondrial Iron-Mediated Immunometabolism

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PKM2 regulates the Warburg effect and promotes HMGB1 release in sepsis

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PanIN-specific regulation of Wnt signaling by HIF2α during early pancreatic tumorigenesis

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Partial purification of murine tumor-associated peptide epitopes common to histologically distinct tumors, melanoma and sarcoma, that are presented by H-2Kb molecules and recognized by CD8+ tumor-infiltrating lymphocytes

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Pathologic findings associated with interleukin-2-based immunotherapy for cancer: a postmortem study of 19 patients

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Paucity of dendritic cells in pancreatic cancer

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Pediatric cancers are infiltrated predominantly by macrophages and contain a paucity of dendritic cells: a major nosologic difference with adult tumors

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Peptide-pulsed dendritic cells induce antigen-specific CTL-mediated protective tumor immunity

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Peritumoral CD1a-Positive Dendritic Cells Are Associated With Improved Survival in Patients With Tongue Carcinoma

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Perpetual change: autophagy, the endothelium, and response to vascular injury

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Pharmacologic administration of interleukin-2.

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Phase I evaluation of intravenous recombinant human interleukin 12 in patients with advanced malignancies

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Platelet-derived HMGB1 is a critical mediator of thrombosis.

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Platelet-derived high-mobility group box 1 promotes recruitment and suppresses apoptosis of monocytes

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Potent antitumor effects mediated by local expression of the mature form of the interferon-gamma inducing factor, interleukin-18 (IL-18).

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Potent antitumor effects of intra-arterial injection of fibroblasts genetically engineered to express IL-12 in liver metastasis model of rat: no additional benefit of using retroviral producer cell

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Principles and current strategies for targeting autophagy for cancer treatment

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Prognostic Value of the Systemic Immune-Inflammation Index (SII) After Neoadjuvant Therapy for Patients with Resected Pancreatic Cancer

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Programmed necrosis induced by asbestos in human mesothelial cells causes high-mobility group box 1 protein release and resultant inflammation.

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Progress in tuberculosis vaccine development and host-directed therapies--a state of the art review.

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Prolactin Promotes Fibrosis and Pancreatic Cancer Progression

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Quercetin prevents LPS-induced high-mobility group box 1 release and proinflammatory function

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RAGE (Receptor for Advanced Glycation Endproducts), RAGE ligands, and their role in cancer and inflammation.

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RAGE is essential for oncogenic KRAS-mediated hypoxic signaling in pancreatic cancer

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RAGE regulates autophagy and apoptosis following oxidative injury

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RAGE-specific single chain Fv for PET imaging of pancreatic cancer.

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Rapid extracellular degradation of synthetic class I peptides by human dendritic cells

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Rapid generation of potent and tumor-specific cytotoxic T lymphocytes by interleukin 18 using dendritic cells and natural killer cells

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Recognition of human renal cell carcinoma and melanoma by HLA-A2-restricted cytotoxic T lymphocytes is mediated by shared peptide epitopes and up-regulated by interferon-gamma

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Report on the ISBTC mini-symposium on biologic effects of targeted therapeutics.

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Report on the Keystone symposium: cellular immunity and the immunotherapy of cancer II

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Results of clinical trials with the administration of interleukin 2 and adoptive immunotherapy with activated cells in patients with cancer

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Retroviral delivery of viral interleukin-10 into myeloid dendritic cells markedly inhibits their allostimulatory activity and promotes the induction of T-cell hyporesponsiveness

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Retrovirus-mediated transfer of viral IL-10 gene prolongs murine cardiac allograft survival

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Role of interleukin-12 (IL12) as an anti-tumour agent: experimental biology and clinical application

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S100A4 and uric acid promote mesenchymal stromal cell induction of IL-10+/IDO+ lymphocytes.

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Safety and Biologic Response of Pre-operative Autophagy Inhibition in Combination with Gemcitabine in Patients with Pancreatic Adenocarcinoma

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Separation and functional studies of the human lymphokine-activated killer cell.

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Serum Proteomic Profiling and Analysis

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Serum and nutrient deprivation increase autophagic flux in intervertebral disc annulus fibrosus cells: an in vitro experimental study

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Serum interleukin-27 in relation to risk of hepatocellular carcinoma in two nested case-control studies

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Signaling of high mobility group box 1 (HMGB1) through toll-like receptor 4 in macrophages requires CD14.

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Spontaneous apoptosis of CD8+ T lymphocytes in peripheral blood of patients with advanced melanoma

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Strange attractors: DAMPs and autophagy link tumor cell death and immunity

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Successful culture and selection of cytokine gene-modified human dermal fibroblasts for the biologic therapy of patients with cancer

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Successful management of hepatic abscesses by percutaneous catheter drainage in chronic granulomatous disease

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Sweating the small stuff: microRNAs and genetic changes define pancreatic cancer

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Synergistic interleukin-18 and low-dose interleukin-2 promote regression of established murine neuroblastoma in vivo

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Systemic administration of cellular IL-10 induces an effective, specific, and long-lived immune response against established tumors in mice

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Systemic administration of interleukin-2 in humans

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Systemic inflammation and remote organ injury following trauma require HMGB1

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TCR usage in CTLs recognizing melanoma/melanocyte antigens

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TLR4-dependent upregulation of the platelet NLRP3 inflammasome promotes platelet aggregation in a murine model of hindlimb ischemia

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TRAIL, Fasl and a blocking anti-DR5 antibody augment paclitaxel-induced apoptosis in human non-small-cell lung cancer

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Targeting Immune Checkpoints in Esophageal Cancer: A High Mutational Load Tumor

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Targeting damage-associated molecular pattern molecules (DAMPs) and DAMP receptors in melanoma.

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The Adaptome as Biomarker for Assessing Cancer Immunity and Immunotherapy

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The Beclin 1 network regulates autophagy and apoptosis

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The HMGB1/RAGE inflammatory pathway promotes pancreatic tumor growth by regulating mitochondrial bioenergetics

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The Multifaceted Effects of Autophagy on the Tumor Microenvironment

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The NLRP3 inflammasome and bruton's tyrosine kinase in platelets co-regulate platelet activation, aggregation, and in vitro thrombus formation.

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The Power of Negative Thinking: Which Cells Limit Tumor Immunity?

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The Receptor for Advanced Glycation End Products Activates the AIM2 Inflammasome in Acute Pancreatitis.

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The Receptor for Advanced Glycation End-Products (RAGE) Protects Pancreatic Tumor Cells Against Oxidative Injury

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The Society for Immunotherapy of Cancer consensus statement on tumour immunotherapy for the treatment of cutaneous melanoma

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The Tumor Suppressor p53 Limits Ferroptosis by Blocking DPP4 Activity

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The Unknown Unknowns: Recovering Gamma-Delta T Cells for Control of Human Immunodeficiency Virus (HIV)

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The VE-PTP Inhibitor AKB-9778 Improves Antitumor Activity and Diminishes the Toxicity of Interleukin 2 (IL-2) Administration

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The biology of interleukin-2 efficacy in the treatment of patients with renal cell carcinoma

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The chemokine receptors CXCR4/CXCR7 and their primary heterodimeric ligands CXCL12 and CXCL12/high mobility group box 1 in pancreatic cancer growth and development: finding flow

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The dendritic cell and human cancer vaccines

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The enhanced tumor selectivity of an oncolytic vaccinia lacking the host range and antiapoptosis genes SPI-1 and SPI-2.

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The expression of the receptor for advanced glycation endproducts (RAGE) is permissive for early pancreatic neoplasia

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The ferroptosis inducer erastin enhances sensitivity of acute myeloid leukemia cells to chemotherapeutic agents

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The grateful dead: damage-associated molecular pattern molecules and reduction/oxidation regulate immunity

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The immunopathology of sequential tumor biopsies in patients treated with interleukin-2. Correlation of response with T-cell infiltration and HLA-DR expression.

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The in vivo distribution of autologous human and murine lymphoid cells grown in T cell growth factor (TCGF): implications for the adoptive immunotherapy of tumors

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The myeloid response to pancreatic carcinogenesis is regulated by the receptor for advanced glycation end-products

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The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion

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The platelet NLRP3 inflammasome is upregulated in a murine model of pancreatic cancer and promotes platelet aggregation and tumor growth

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The receptor for advanced glycation end products (RAGE) enhances autophagy and neutrophil extracellular traps in pancreatic cancer

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The receptor for advanced glycation end products (RAGE) sustains autophagy and limits apoptosis, promoting pancreatic tumor cell survival

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The receptor for advanced glycation end products promotes pancreatic carcinogenesis and accumulation of myeloid-derived suppressor cells

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The role of interleukin-2, interleukin-12, and dendritic cells in cancer therapy

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The systemic administration of purified interleukin 2 enhances the ability of sensitized murine lymphocytes to cure a disseminated syngeneic lymphoma

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The use of dendritic cells for cancer vaccination.

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Therapeutic and specific antitumor immunity induced by co-administration of immature dendritic cells and adenoviral vector expressing biologically active IL-18.

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Therapy of murine tumors with p53 wild-type and mutant sequence peptide-based vaccines

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Therapy of murine tumors with tumor peptide-pulsed dendritic cells: dependence on T cells, B7 costimulation, and T helper cell 1-associated cytokines

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Toward a comprehensive view of cancer immune responsiveness: a synopsis from the SITC workshop

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Tumor escape from immune recognition: lethal recurrent melanoma in a patient associated with downregulation of the peptide transporter protein TAP-1 and loss of expression of the immunodominant MART-1/Melan-A antigen.

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Tumor escape from immune recognition: loss of HLA-A2 melanoma cell surface expression is associated with a complex rearrangement of the short arm of chromosome 6.

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Tumor recognition by the cellular immune system: new aspects of tumor immunology.

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Tumor's other immune targets: dendritic cells

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Tumor-Cell Death, Autophagy, and Immunity

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Usage of T-cell receptor V beta chain genes in fresh and cultured tumor-infiltrating lymphocytes from human melanoma

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Use of T-cell growth factors (interleukins 2, 4, 7, 10, and 12) in the evaluation of T-cell reactivity to melanoma

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Use of tumor-infiltrating lymphocytes and interleukin-2 in the immunotherapy of patients with metastatic melanoma. A preliminary report

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Vaccination of metastatic colorectal cancer patients with matured dendritic cells loaded with multiple major histocompatibility complex class I peptides

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Viral interleukin 10 (IL-10), the human herpes virus 4 cellular IL-10 homologue, induces local anergy to allogeneic and syngeneic tumors

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Workshop on cancer biometrics: identifying biomarkers and surrogates of cancer in patients: a meeting held at the Masur Auditorium, National Institutes of Health.

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You eat what you are: autophagy inhibition as a therapeutic strategy in leukemia

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Zinc in innate and adaptive tumor immunity.

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miR-17-92 expression in differentiated T cells - implications for cancer immunotherapy

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microRNA 30A promotes autophagy in response to cancer therapy

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p53/HMGB1 complexes regulate autophagy and apoptosis.

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